메뉴 건너뛰기




Volumn 13, Issue 5, 2006, Pages 843-851

NF-κB-related genetic diseases

Author keywords

CYLD; Cylindromatosis; Incontinentia pigmenti, anhidrotic ectodermal dysplasia with immunodeficiency; NEMO; NF B

Indexed keywords

I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3; CYLD PROTEIN, HUMAN; I KAPPA B; I KAPPA B KINASE; IKBKG PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

EID: 33645987311     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401841     Document Type: Review
Times cited : (72)

References (76)
  • 1
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination : The control of NF-κB activity
    • Karin M and Ben-Neriah Y (2000) Phosphorylation meets ubiquitination : the control of NF-κB activity. Ann. Rev. Immunol. 18: 621-663
    • (2000) Ann. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 2
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS and Ghosh S (2004) Signaling to NF-κB. Genes Dev. 18: 2195-2224
    • (2004) Genes Dev. , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 3
    • 0034175930 scopus 로고    scopus 로고
    • The IKK complex: An integrator of all signals that activate NF-κB?
    • Israël A (2000) The IKK complex: An integrator of all signals that activate NF-κB? Trends Cell Biol. 10: 129-133
    • (2000) Trends Cell Biol. , vol.10 , pp. 129-133
    • Israël, A.1
  • 4
    • 0036187476 scopus 로고    scopus 로고
    • TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
    • Chen G, Cao P and Goeddel DV (2002) TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. Mol. Cell 9: 401-410
    • (2002) Mol. Cell , vol.9 , pp. 401-410
    • Chen, G.1    Cao, P.2    Goeddel, D.V.3
  • 5
    • 3042523535 scopus 로고    scopus 로고
    • Activation of transcription factor NF-κB requires ELKS, an IκB kinase regulatory subunit
    • Ducut Sigala JL, Bottero V, Young DB, Shevchenko A, Mercurio F and Verma IM (2004) Activation of transcription factor NF-κB requires ELKS, an IκB kinase regulatory subunit. Science 304: 1963-1967
    • (2004) Science , vol.304 , pp. 1963-1967
    • Ducut Sigala, J.L.1    Bottero, V.2    Young, D.B.3    Shevchenko, A.4    Mercurio, F.5    Verma, I.M.6
  • 7
    • 0032589261 scopus 로고    scopus 로고
    • IKKγ mediates the interaction of cellular IκB kinases with the tax transforming protein of human T cell leukemia virus type 1
    • Chu ZL, Shin YA, Yang JM, DiDonato JA and Ballard DW (1999) IKKγ mediates the interaction of cellular IκB kinases with the tax transforming protein of human T cell leukemia virus type 1. J. Biol. Chem. 274: 15297-15300
    • (1999) J. Biol. Chem. , vol.274 , pp. 15297-15300
    • Chu, Z.L.1    Shin, Y.A.2    Yang, J.M.3    DiDonato, J.A.4    Ballard, D.W.5
  • 8
    • 0033712615 scopus 로고    scopus 로고
    • Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
    • Zhang SQ, Kovalenko A, Cantarella G and Wallach D (2000) Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation. Immunity 12: 301-311
    • (2000) Immunity , vol.12 , pp. 301-311
    • Zhang, S.Q.1    Kovalenko, A.2    Cantarella, G.3    Wallach, D.4
  • 9
    • 3142546430 scopus 로고    scopus 로고
    • The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains
    • Agou F, Traincard F, Vinolo E, Courtois G, Yamaoka S, Israël A and Véron M (2004) The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains. J. Biol. Chem. 279: 27861-27869
    • (2004) J. Biol. Chem. , vol.279 , pp. 27861-27869
    • Agou, F.1    Traincard, F.2    Vinolo, E.3    Courtois, G.4    Yamaoka, S.5    Israël, A.6    Véron, M.7
  • 10
    • 0036724051 scopus 로고    scopus 로고
    • The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation
    • Makris C, Roberts JL and Karin M (2002) The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation. Mol. Cell. Biol. 22: 6573-6581
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6573-6581
    • Makris, C.1    Roberts, J.L.2    Karin, M.3
  • 11
    • 0033051635 scopus 로고    scopus 로고
    • Isolation of full-length cDNA and chromosomal localization of human NF-κB modulator NEMO to Xq28
    • Jin D and Jeang KT (1999) Isolation of full-length cDNA and chromosomal localization of human NF-κB modulator NEMO to Xq28. J. Biochem. Sci. 6: 115-120
    • (1999) J. Biochem. Sci. , vol.6 , pp. 115-120
    • Jin, D.1    Jeang, K.T.2
  • 13
    • 0027403249 scopus 로고
    • Incontinentia pigmenti (Bloch-Sulzberger syndrome)
    • Landi SJ and Donnai D (1993) Incontinentia pigmenti (Bloch-Sulzberger syndrome). J. Med. Genet. 30: 53-59
    • (1993) J. Med. Genet. , vol.30 , pp. 53-59
    • Landi, S.J.1    Donnai, D.2
  • 14
    • 0036696739 scopus 로고    scopus 로고
    • Incontinentia pigmenti: A review and update on the molecular basis of pathophysiology
    • Berlin AL, Paller AS and Chan LS (2002) Incontinentia pigmenti: A review and update on the molecular basis of pathophysiology. J. Am. Acad. Dermatol. 47: 169-187
    • (2002) J. Am. Acad. Dermatol. , vol.47 , pp. 169-187
    • Berlin, A.L.1    Paller, A.S.2    Chan, L.S.3
  • 15
    • 0027360939 scopus 로고
    • Incontinentia pigmenti: Clinical and neuroradiologic features
    • Manago S and Barbagallo A (1993) Incontinentia pigmenti: Clinical and neuroradiologic features. Brain Dev. 15: 362-366
    • (1993) Brain Dev. , vol.15 , pp. 362-366
    • Manago, S.1    Barbagallo, A.2
  • 16
    • 0029062691 scopus 로고
    • Intracranial assessment of incontinentia pigmenti using magnetic resonance imaging, angiography, and spectroscopic imaging
    • Lee AG, Goldberg MF, Gillard JH, Barker PB and Bryan RN (1995) Intracranial assessment of incontinentia pigmenti using magnetic resonance imaging, angiography, and spectroscopic imaging. Arch. Pediatr. Adolesc. Med. 149: 573-580
    • (1995) Arch. Pediatr. Adolesc. Med. , vol.149 , pp. 573-580
    • Lee, A.G.1    Goldberg, M.F.2    Gillard, J.H.3    Barker, P.B.4    Bryan, R.N.5
  • 17
    • 0142248341 scopus 로고    scopus 로고
    • Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti
    • Hennel SJ, Ekert PG, Volpe JJ and Inder TE (2003) Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti. Pediatr. Neurol. 29: 148-150
    • (2003) Pediatr. Neurol. , vol.29 , pp. 148-150
    • Hennel, S.J.1    Ekert, P.G.2    Volpe, J.J.3    Inder, T.E.4
  • 18
    • 0027274091 scopus 로고
    • Interaction of incontinentia pigmenti and factor VIII mutations in a female with biased X inactivation, resulting in haemophilia
    • Coleman R, Genet SA, Harper JI and Wilkie AO (1993) Interaction of incontinentia pigmenti and factor VIII mutations in a female with biased X inactivation, resulting in haemophilia. J. Med. Genet. 30: 497-500
    • (1993) J. Med. Genet. , vol.30 , pp. 497-500
    • Coleman, R.1    Genet, S.A.2    Harper, J.I.3    Wilkie, A.O.4
  • 22
    • 4444311888 scopus 로고    scopus 로고
    • Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-κB activation
    • Fusco F, Bardaro T, Fimiani G, Mercadante V, Miano M, Falco G, Israël A, Courtois G, D'Urso M and Ursini MV (2004) Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-κB activation. Hum. Mol. Genet. 13: 1763-1773
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 1763-1773
    • Fusco, F.1    Bardaro, T.2    Fimiani, G.3    Mercadante, V.4    Miano, M.5    Falco, G.6    Israël, A.7    Courtois, G.8    D'Urso, M.9    Ursini, M.V.10
  • 24
    • 0034037959 scopus 로고    scopus 로고
    • Incontinentia pigmenti: An extensive second episode of a 'first-stage' vesicobullous eruption
    • van Leeuwen RL, Wintzen M and van Praag MC (2000) Incontinentia pigmenti: An extensive second episode of a 'first-stage' vesicobullous eruption. Pediatr. Dermatol. 17: 70-74
    • (2000) Pediatr. Dermatol. , vol.17 , pp. 70-74
    • van Leeuwen, R.L.1    Wintzen, M.2    van Praag, M.C.3
  • 25
    • 0037323065 scopus 로고    scopus 로고
    • Late recurrence of inflammatory first-stage lesions in incontinentia pigmenti: An unusual phenomenon and a fascinating pathologic mechanism
    • Bodak N, Hadj-Rabia S, Hamel-Teillac D, de Prost Y and Bodemer C (2003) Late recurrence of inflammatory first-stage lesions in incontinentia pigmenti: An unusual phenomenon and a fascinating pathologic mechanism. Arch. Dermatol. 139: 201-204
    • (2003) Arch. Dermatol. , vol.139 , pp. 201-204
    • Bodak, N.1    Hadj-Rabia, S.2    Hamel-Teillac, D.3    de Prost, Y.4    Bodemer, C.5
  • 26
    • 0022903301 scopus 로고
    • Acute miliary tuberculosis in a child with anhidrotic ectodermal dysplasia
    • Frix CD and Bronson DM (1986) Acute miliary tuberculosis in a child with anhidrotic ectodermal dysplasia. Pediatr. Dermatol. 3: 464-467
    • (1986) Pediatr. Dermatol. , vol.3 , pp. 464-467
    • Frix, C.D.1    Bronson, D.M.2
  • 27
    • 0026563059 scopus 로고
    • Extramedullary hematopoieisis of the cranial dura and anhidrotic ectodermal dysplasia
    • Sitton JE and Reimund EL (1992) Extramedullary hematopoieisis of the cranial dura and anhidrotic ectodermal dysplasia. Neuropediatrics 23: 108-110
    • (1992) Neuropediatrics , vol.23 , pp. 108-110
    • Sitton, J.E.1    Reimund, E.L.2
  • 28
    • 0030033284 scopus 로고    scopus 로고
    • Anhidrotic ectodermal dysplasia associated with specific antibody deficiency
    • Abinun M, Spickett G, Appleton AL, Flood T and Cant AJ (1996) Anhidrotic ectodermal dysplasia associated with specific antibody deficiency. Eur. J. Pediatr. 155: 146-147
    • (1996) Eur. J. Pediatr. , vol.155 , pp. 146-147
    • Abinun, M.1    Spickett, G.2    Appleton, A.L.3    Flood, T.4    Cant, A.J.5
  • 29
    • 0032718893 scopus 로고    scopus 로고
    • Polysaccharide specific humoral immunodeficiency in ectodermal dysplasia. Case report of a boy with two affected brothers
    • Schneider P, Kalhoff H, Horneff G, Wahn V and Diekmann L (1999) Polysaccharide specific humoral immunodeficiency in ectodermal dysplasia. Case report of a boy with two affected brothers. Klin. Padiatr. 211: 459-461
    • (1999) Klin. Padiatr. , vol.211 , pp. 459-461
    • Schneider, P.1    Kalhoff, H.2    Horneff, G.3    Wahn, V.4    Diekmann, L.5
  • 30
    • 0033658369 scopus 로고    scopus 로고
    • A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKKγ(NEMO)
    • Zonana J, Elder ME, Schneider LC, Orlow SJ, Moss C and Golabi M (2000) A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKKγ(NEMO). Am. J. Hum. Genet. 67: 1555-1562
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1555-1562
    • Zonana, J.1    Elder, M.E.2    Schneider, L.C.3    Orlow, S.J.4    Moss, C.5    Golabi, M.6
  • 32
    • 0035089759 scopus 로고    scopus 로고
    • Atypical forms of Incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-γ)
    • Aradhya S, Courtois G, Rajkovic A, Lewis AL, Levy M, Israël A and Nelson DL (2001a) Atypical forms of Incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-γ). Am. J. Hum. Genet. 68: 765-771
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 765-771
    • Aradhya, S.1    Courtois, G.2    Rajkovic, A.3    Lewis, A.L.4    Levy, M.5    Israël, A.6    Nelson, D.L.7
  • 33
    • 0035286726 scopus 로고    scopus 로고
    • Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia
    • Jain A, Ma CA, Liu S, Brown M, Cohen J and Strober W (2001) Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia. Nat. Immunol. 2: 223-228
    • (2001) Nat. Immunol. , vol.2 , pp. 223-228
    • Jain, A.1    Ma, C.A.2    Liu, S.3    Brown, M.4    Cohen, J.5    Strober, W.6
  • 34
    • 1942500166 scopus 로고    scopus 로고
    • The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation
    • Orange JS, Jain A, Ballas ZK, Schneider LC, Geha RS and Bonilla FA (2004) The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation. J. Allergy Clin. Immunol. 113: 725-733
    • (2004) J. Allergy Clin. Immunol. , vol.113 , pp. 725-733
    • Orange, J.S.1    Jain, A.2    Ballas, Z.K.3    Schneider, L.C.4    Geha, R.S.5    Bonilla, F.A.6
  • 35
    • 33646012548 scopus 로고    scopus 로고
    • Late skewed x-chromosome inactivation in incontinentia pigmenti female patient with immunodeficiency: A new mutation in NEMO gene exon 7
    • (in press)
    • Martinez-Pomar N, Muñoz-Saa I, Heine-Suñer D, Martin A, Smahi A and Matamoros N. Late skewed x-chromosome inactivation in incontinentia pigmenti female patient with immunodeficiency: A new mutation in NEMO gene exon 7. Hum. Genet. (in press)
    • Hum. Genet.
    • Martinez-Pomar, N.1    Muñoz-Saa, I.2    Heine-Suñer, D.3    Martin, A.4    Smahi, A.5    Matamoros, N.6
  • 36
    • 16644377329 scopus 로고    scopus 로고
    • Pleiotropic function of Toll-like receptors
    • Kaisho T and Akira S (2004) Pleiotropic function of Toll-like receptors. Microbes Infect. 6: 1388-1394
    • (2004) Microbes Infect. , vol.6 , pp. 1388-1394
    • Kaisho, T.1    Akira, S.2
  • 38
    • 0028127041 scopus 로고
    • Ectodermal dysplasia: A clinical classification and a causal review
    • Pinheiro M and Freire-Maia N (1994) Ectodermal dysplasia: A clinical classification and a causal review. Am. J. Med. Genet. 53: 153-162
    • (1994) Am. J. Med. Genet. , vol.53 , pp. 153-162
    • Pinheiro, M.1    Freire-Maia, N.2
  • 41
    • 0032852542 scopus 로고    scopus 로고
    • Ectodysplasin is a collagenous trimeric type II membrane protein with a tumour necrosis factor-like domain and co-localize with cytoskeletal structures at lateral and apical surfaces of cells
    • Ezer S, Bayes M, Elomaa O, Schlessinger D and Kere J (1999) Ectodysplasin is a collagenous trimeric type II membrane protein with a tumour necrosis factor-like domain and co-localize with cytoskeletal structures at lateral and apical surfaces of cells. Hum. Mol. Genet. 8: 2079-2086
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 2079-2086
    • Ezer, S.1    Bayes, M.2    Elomaa, O.3    Schlessinger, D.4    Kere, J.5
  • 42
    • 0032850832 scopus 로고    scopus 로고
    • Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion
    • Mikkola ML, Pispa J, Pekkanen M, Paulin L, Nieminen P, Kere J and Thesleff I (1999) Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion. Mech. Dev. 88: 133-146
    • (1999) Mech. Dev. , vol.88 , pp. 133-146
    • Mikkola, M.L.1    Pispa, J.2    Pekkanen, M.3    Paulin, L.4    Nieminen, P.5    Kere, J.6    Thesleff, I.7
  • 44
    • 0032775933 scopus 로고    scopus 로고
    • Involvement of a novel Tnf receptor homologue in hair follicle induction
    • Headon DJ and Overbeek PA (1999) Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet. 22: 370-374
    • (1999) Nat Genet. , vol.22 , pp. 370-374
    • Headon, D.J.1    Overbeek, P.A.2
  • 45
    • 0032811085 scopus 로고    scopus 로고
    • Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia
    • Monreal AW, Ferguson BM, Headon DJ, Street SL, Overbeek PA and Zonana J (1999) Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet. 22: 366-369
    • (1999) Nat Genet. , vol.22 , pp. 366-369
    • Monreal, A.W.1    Ferguson, B.M.2    Headon, D.J.3    Street, S.L.4    Overbeek, P.A.5    Zonana, J.6
  • 47
    • 0035951783 scopus 로고    scopus 로고
    • Ectodermal dysplasia receptor activates the nuclear factor κB, c-Jun N-terminal kinase and cell death pathways and binds to ectodysplasin A
    • Kumar A, Eby MT, Sinha S, Jasmin A and Chaudhary PM (2000) Ectodermal dysplasia receptor activates the nuclear factor κB, c-Jun N-terminal kinase and cell death pathways and binds to ectodysplasin A. J. Biol. Chem. 276: 2668-2677
    • (2000) J. Biol. Chem. , vol.276 , pp. 2668-2677
    • Kumar, A.1    Eby, M.T.2    Sinha, S.3    Jasmin, A.4    Chaudhary, P.M.5
  • 49
    • 0035862916 scopus 로고    scopus 로고
    • TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelia signaling centers and is regulated by Wnt and activin during tooth organogenesis
    • Laurikkala J, Mikkola M, Mustonen T, Aberg T, Koppinen P, Pispa J, Nieminen P, Galceran J, Grosschedl R and Thesleff I (2001) TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelia signaling centers and is regulated by Wnt and activin during tooth organogenesis. Dev. Biol. 229: 443-455
    • (2001) Dev. Biol. , vol.229 , pp. 443-455
    • Laurikkala, J.1    Mikkola, M.2    Mustonen, T.3    Aberg, T.4    Koppinen, P.5    Pispa, J.6    Nieminen, P.7    Galceran, J.8    Grosschedl, R.9    Thesleff, I.10
  • 51
    • 0037022539 scopus 로고    scopus 로고
    • Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice
    • Yan M, Zhang Z, Brady JR, Schilbach S, Fairbrother WJ and Dixit VM (2002) Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice. Curr. Biol. 12: 409-413
    • (2002) Curr. Biol. , vol.12 , pp. 409-413
    • Yan, M.1    Zhang, Z.2    Brady, J.R.3    Schilbach, S.4    Fairbrother, W.J.5    Dixit, V.M.6
  • 53
    • 0035281865 scopus 로고    scopus 로고
    • Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection
    • Mansour S, Woffendin H, Mitton S, Jeffery I, Jakins T, Kenwrick S and Murday VA (2001) Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection. Am. J. Med. Genet. 99: 172-177
    • (2001) Am. J. Med. Genet. , vol.99 , pp. 172-177
    • Mansour, S.1    Woffendin, H.2    Mitton, S.3    Jeffery, I.4    Jakins, T.5    Kenwrick, S.6    Murday, V.A.7
  • 60
    • 0142025179 scopus 로고    scopus 로고
    • Recurrent 'sterile' verrucous cyst abscesses and epidermodysplasia verruciformis-like eruption associated with idiopathic CD4 lymphopenia
    • Tobin E, Rohwedder A, Holland SM, Philips B and Carlson JA (2003) Recurrent 'sterile' verrucous cyst abscesses and epidermodysplasia verruciformis-like eruption associated with idiopathic CD4 lymphopenia. Br. J. Dermatol. 149: 627-633
    • (2003) Br. J. Dermatol. , vol.149 , pp. 627-633
    • Tobin, E.1    Rohwedder, A.2    Holland, S.M.3    Philips, B.4    Carlson, J.A.5
  • 67
    • 3442883360 scopus 로고    scopus 로고
    • Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene
    • Salhi A, Bornholdt D, Oeffner F, Malik S, Heid E, Happle R and Grzeschik KH (2004) Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene. Cancer Res. 64: 5113-5117
    • (2004) Cancer Res. , vol.64 , pp. 5113-5117
    • Salhi, A.1    Bornholdt, D.2    Oeffner, F.3    Malik, S.4    Heid, E.5    Happle, R.6    Grzeschik, K.H.7
  • 69
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
    • Trompouki E, Hatzivassiliou E, Tsichritzis T, Farmer H, Ashworth A and Mosialos G (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members. Nature 424: 793-796
    • (2003) Nature , vol.424 , pp. 793-796
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3    Farmer, H.4    Ashworth, A.5    Mosialos, G.6
  • 70
    • 0346333095 scopus 로고    scopus 로고
    • The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor
    • Regamey A, Hohl D, Liu JW, Roger T, Kogerman P, Toftgard R and Huber M (2003) The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. J. Exp. Med. 198: 1959-1964
    • (2003) J. Exp. Med. , vol.198 , pp. 1959-1964
    • Regamey, A.1    Hohl, D.2    Liu, J.W.3    Roger, T.4    Kogerman, P.5    Toftgard, R.6    Huber, M.7
  • 71
    • 0042467554 scopus 로고    scopus 로고
    • Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
    • Brummelkamp TR, Nijman SM, Dirac AM and Bernards R (2003) Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB. Nature 424: 797-801
    • (2003) Nature , vol.424 , pp. 797-801
    • Brummelkamp, T.R.1    Nijman, S.M.2    Dirac, A.M.3    Bernards, R.4
  • 72
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-κB pathway
    • Chen ZJ (2005) Ubiquitin signalling in the NF-κB pathway Nature Cell. Biology 7: 758-765
    • (2005) Nature Cell. Biology , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 73
    • 11244341060 scopus 로고    scopus 로고
    • Negative regulation of JNK signaling by the tumor suppressor CYLD
    • Reiley W, Zhang M and Sun SC (2004) Negative regulation of JNK signaling by the tumor suppressor CYLD. J. Biol. Chem. 279: 55161-55167
    • (2004) J. Biol. Chem. , vol.279 , pp. 55161-55167
    • Reiley, W.1    Zhang, M.2    Sun, S.C.3
  • 74
    • 0036775463 scopus 로고    scopus 로고
    • IRAK-4 as the central TIR signaling mediator in innate immunity
    • Suzuki N, Suzuki S and Yeh WC (2002) IRAK-4 as the central TIR signaling mediator in innate immunity. Trends Immunol. 23: 503-506
    • (2002) Trends Immunol. , vol.23 , pp. 503-506
    • Suzuki, N.1    Suzuki, S.2    Yeh, W.C.3
  • 76
    • 0043281537 scopus 로고    scopus 로고
    • Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysacharide and interleukin-1 in a patient with recurrent bacterial infections
    • Medvedev AE, Lentschat A, Kuhns DB, Blanco JCG, Salkowski C, Zhang S, Arditi M, Gallin JI and Vogel SN (2003) Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysacharide and interleukin-1 in a patient with recurrent bacterial infections. J. Exp. Med. 198: 521-531
    • (2003) J. Exp. Med. , vol.198 , pp. 521-531
    • Medvedev, A.E.1    Lentschat, A.2    Kuhns, D.B.3    Blanco, J.C.G.4    Salkowski, C.5    Zhang, S.6    Arditi, M.7    Gallin, J.I.8    Vogel, S.N.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.