Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis

Development

Volumn 127, Issue 21, 2000, Pages 4691-4700

  Tucker, A S ^a   Headon, D J ^a   Schneider, P ^a   Ferguson, B M ^a   Overbeek, P ^a   Tschopp, J ^a   Sharpe, P T ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

Downless; EDA; EDAR; Enamel knot; Tooth; Tubby

Indexed keywords

COLLAGEN; CYSTEINE; ECTODYSPLASIN A; LIGAND; MEMBRANE PROTEIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR DERIVATIVE; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENAMEL; EPITHELIUM; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC CODE; GERM CELL; HAIR DISEASE; HAIR FOLLICLE; IN VITRO STUDY; MESENCHYME; MORPHOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SWEAT GLAND; SWEAT GLAND DISEASE; TOOTH DEVELOPMENT; TOOTH MALFORMATION;

AMELOGENESIS; ANIMALS; APOPTOSIS; ECTODYSPLASINS; EDAR RECEPTOR; EMBRYONIC AND FETAL DEVELOPMENT; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MORPHOGENESIS; MUTATION; ODONTOGENESIS; ORGAN CULTURE TECHNIQUES; PHENOTYPE; RECEPTORS, ECTODYSPLASIN; RECEPTORS, TUMOR NECROSIS FACTOR; TOOTH; TOOTH GERM;

ANIMALIA;

EID: 0033693832     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Death receptors: Signaling and modulation
2. The anhidrotic ectodermal dsyplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats
3. The ontogeny of molar pattern
4. Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas
5. Clinical and radiographic dental findings in X-linked hypohidrotic ectodermal dysplasia
6. Analysis of epithelial-mesenchmal interactions in the initial morphogenesis of the mammalian tooth
7. Anhidotic ectodermal dysplasia (EDA) protein expressed in MCF-7 cells associates with cell membrane and induces rounding
8. A totally sex-linked gene in the house mouse
9. The death domain: A module shared by proteins with diverse cellular functions
10. Cloning of Tabby, the murine homologue of the human EDA gene: Evidence for a membrane associated protein with a short collagenous domain
11. An apparent new member of the TNF superfamily is encoded for by the EDA1 gene: Evidence from mutation and two-hybrid analysis
12. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
13. Genes and genotypes affecting the teeth of the mouse
14. The molars of the tabby mouse, and a test of the 'single activated X-chromosome' hypothesis
15. The glandular aspect of the tabby syndrome in the mouse
16. Involvement of a novel TNF receptor homolog in hair follicle development
17. β-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
18. Evidence for the role of the enamel knot as a control centre in mammalian tooth cusp formation: Non dividing cells express growth factor Fgf-4 gene
19. Mammalian molar cusp patterns: Developmental mechanisms of diversity
20. The life history of an embryonic signalling center: BMP4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot
21. X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by a mutation in a novel transmembrane protein
22. Lef-1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development
23. Site of action of the crinkled (cr) locus in the mouse
24. Alterations in the incisor development in the Tabby mouse
25. FasL independent, FADD-mediated activation of the Fas death pathway by anti-cancer drugs
26. Characterisation of the mouse Tabby protein, mutation of which causes ectodermal dysplasia
27. Ectodysplasin, a protein required for epithelial morphogensis, is a novel TNF homologue and promotes cell-matrix adhesion
28. The gene defective in anhidrotic ectodermal dysplasia is expressed in developing epithelium, neuroectoderm, thymus and bone
29. Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations
30. Mutations in the human homolog of the mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia
31. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
32. Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF
33. Expression of Wnt signalling pathway genes during tooth development
34. The effect of Tetracyclin on osteogenesis in vitro
35. BAFF, a novel ligand of the TNF family stimulates B cell growth
36. Production of recombinant TRAIL and TRAIL receptors: Fc chimeric proteins
37. Aspects of the tabby-crinkled-downless syndrome I. The development of tabby teeth
38. Aspects of the tabby-crinkled-downless syndrome II. Observations on the reaction to changes of genetic background
39. Short communication: The teeth of the 'Sleek' mouse
40. The Tabby phenotype is caused by mutations in a mouse homoloue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains
41. The Downless (dl) and Sleek (D1(Sleek)) mutations, Chromosome 10
42. The culture of mature organs in a synthetic medium
43. Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development
44. Molecular genetics of tooth morphogenesis and patterning: The right shape in the right place
45. Apoptosis in the developing tooth: Association with an embryonic signalling centre and suppression by EGF and FGF-4
46. The enamel knot as a signalling centre in the developing mouse tooth
47. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1 deficient mice
48. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate