메뉴 건너뛰기




Volumn 163, Issue 3, 2006, Pages 224-234

Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors α and γ in breast

Author keywords

Breast; Human; MBP; MEHP; PPAR

Indexed keywords

ISOPROTEIN; N BUTYLPHTHALATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 33645864928     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.11.001     Document Type: Article
Times cited : (49)

References (51)
  • 3
    • 0031890427 scopus 로고    scopus 로고
    • Effects of xenoestrogenic environmental pollutants on the proliferation of a human breast cancer cell line (MCF-7)
    • Blom A., Ekman E., Johannisson A., Norrgren L., and Pesonen M. Effects of xenoestrogenic environmental pollutants on the proliferation of a human breast cancer cell line (MCF-7). Arch. Environ. Contam. Toxicol. 34 3 (1998) 306-310
    • (1998) Arch. Environ. Contam. Toxicol. , vol.34 , Issue.3 , pp. 306-310
    • Blom, A.1    Ekman, E.2    Johannisson, A.3    Norrgren, L.4    Pesonen, M.5
  • 6
    • 0033767327 scopus 로고    scopus 로고
    • Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development
    • Colon I., Caro D., Bourdony C.J., and Rosario O. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ. Health Perspect. 108 9 (2000) 895-900
    • (2000) Environ. Health Perspect. , vol.108 , Issue.9 , pp. 895-900
    • Colon, I.1    Caro, D.2    Bourdony, C.J.3    Rosario, O.4
  • 7
    • 0027948537 scopus 로고
    • Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats
    • Davis B.J., Maronpot R.R., and Heindel J.J. Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats. Toxicol. Appl. Pharmacol. 128 2 (1994) 216-223
    • (1994) Toxicol. Appl. Pharmacol. , vol.128 , Issue.2 , pp. 216-223
    • Davis, B.J.1    Maronpot, R.R.2    Heindel, J.J.3
  • 8
    • 0022390449 scopus 로고
    • Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin
    • Diwan B.A., Ward J.M., Rice J.M., Colburn N.H., and Spangler E.F. Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin. Carcinogenesis 6 3 (1985) 343-347
    • (1985) Carcinogenesis , vol.6 , Issue.3 , pp. 343-347
    • Diwan, B.A.1    Ward, J.M.2    Rice, J.M.3    Colburn, N.H.4    Spangler, E.F.5
  • 9
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E., Muller C., Koshizuka K., Williamson E.A., Park D., Asou H., Shintaku P., Said J.W., Heber D., and Koeffler H.P. Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc. Natl. Acad. Sci. U.S.A. 95 15 (1998) 8806-8811
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.15 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 10
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans R.M. The steroid and thyroid hormone receptor superfamily. Science 240 4854 (1988) 889-895
    • (1988) Science , vol.240 , Issue.4854 , pp. 889-895
    • Evans, R.M.1
  • 11
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman B.M., Chen J., and Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc. Natl. Acad. Sci. U.S.A. 94 9 (1997) 4312-4317
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , Issue.9 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 12
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., and Evans R.M. 15-Deoxy-delta 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83 5 (1995) 803-812
    • (1995) Cell , vol.83 , Issue.5 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 13
    • 1942470331 scopus 로고    scopus 로고
    • Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
    • Gupta R.A., Wang D., Katkuri S., Wang H., Dey S.K., and DuBois R.N. Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat. Med. 10 3 (2004) 245-247
    • (2004) Nat. Med. , vol.10 , Issue.3 , pp. 245-247
    • Gupta, R.A.1    Wang, D.2    Katkuri, S.3    Wang, H.4    Dey, S.K.5    DuBois, R.N.6
  • 14
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He T.C., Chan T.A., Vogelstein B., and Kinzler K.W. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99 3 (1999) 335-345
    • (1999) Cell , vol.99 , Issue.3 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 15
    • 0024565234 scopus 로고
    • Inhibition of FSH-stimulated cAMP accumulation by mono(2-ethylhexyl) phthalate in primary rat Sertoli cell cultures
    • Heindel J.J., and Chapin R.E. Inhibition of FSH-stimulated cAMP accumulation by mono(2-ethylhexyl) phthalate in primary rat Sertoli cell cultures. Toxicol. Appl. Pharmacol. 97 2 (1989) 377-385
    • (1989) Toxicol. Appl. Pharmacol. , vol.97 , Issue.2 , pp. 377-385
    • Heindel, J.J.1    Chapin, R.E.2
  • 16
    • 0041352906 scopus 로고    scopus 로고
    • Activation of PPARa and PPARg by environmental phthalate monoesters
    • Hurst C.H., and Waxman D.J. Activation of PPARa and PPARg by environmental phthalate monoesters. Toxicol. Sci. 74 2 (2003) 297-308
    • (2003) Toxicol. Sci. , vol.74 , Issue.2 , pp. 297-308
    • Hurst, C.H.1    Waxman, D.J.2
  • 17
    • 33645891927 scopus 로고    scopus 로고
    • International Agency for Research on Cancer, 2003. World Cancer Report. Stewart BaK, IARC Press, Lyon.
  • 18
    • 0027314960 scopus 로고
    • The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor
    • Issemann I., Prince R.A., Tugwood J.D., and Green S. The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor. Biochimie 75 3-4 (1993) 251-256
    • (1993) Biochimie , vol.75 , Issue.3-4 , pp. 251-256
    • Issemann, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 20
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., Heyman R.A., and Evans R.M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358 6389 (1992) 771-774
    • (1992) Nature , vol.358 , Issue.6389 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 21
    • 0020444298 scopus 로고
    • The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice
    • Kluwe W.M., Haseman J.K., Douglas J.F., and Huff J.E. The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice. J. Toxicol. Environ. Health 10 4-5 (1982) 797-815
    • (1982) J. Toxicol. Environ. Health , vol.10 , Issue.4-5 , pp. 797-815
    • Kluwe, W.M.1    Haseman, J.K.2    Douglas, J.F.3    Huff, J.E.4
  • 22
    • 0034721937 scopus 로고    scopus 로고
    • Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators
    • Kodera Y., Takeyama K., Murayama A., Suzawa M., Masuhiro Y., and Kato S. Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators. J. Biol. Chem. 275 43 (2000) 33201-33204
    • (2000) J. Biol. Chem. , vol.275 , Issue.43 , pp. 33201-33204
    • Kodera, Y.1    Takeyama, K.2    Murayama, A.3    Suzawa, M.4    Masuhiro, Y.5    Kato, S.6
  • 23
    • 0029977518 scopus 로고    scopus 로고
    • A human peroxisome-proliferator-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs
    • Lambe K.G., and Tugwood J.D. A human peroxisome-proliferator-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs. Eur. J. Biochem. 239 1 (1996) 1-7
    • (1996) Eur. J. Biochem. , vol.239 , Issue.1 , pp. 1-7
    • Lambe, K.G.1    Tugwood, J.D.2
  • 24
    • 0037380046 scopus 로고    scopus 로고
    • Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells
    • Lampen A., Zimnik S., and Nau H. Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells. Toxicol. Appl. Pharmacol. 188 1 (2003) 14-23
    • (2003) Toxicol. Appl. Pharmacol. , vol.188 , Issue.1 , pp. 14-23
    • Lampen, A.1    Zimnik, S.2    Nau, H.3
  • 26
    • 0023625630 scopus 로고
    • The use of multivariate analysis to compare peroxisome induction data on phthalate esters in rats
    • Lin L.I. The use of multivariate analysis to compare peroxisome induction data on phthalate esters in rats. Toxicol. Ind. Health 3 2 (1987) 25-48
    • (1987) Toxicol. Ind. Health , vol.3 , Issue.2 , pp. 25-48
    • Lin, L.I.1
  • 27
    • 0035341453 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells
    • Lovekamp T.N., and Davis B.J. Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells. Toxicol. Appl. Pharmacol. 172 3 (2001) 217-224
    • (2001) Toxicol. Appl. Pharmacol. , vol.172 , Issue.3 , pp. 217-224
    • Lovekamp, T.N.1    Davis, B.J.2
  • 28
    • 0037295361 scopus 로고    scopus 로고
    • Mechanisms of phthalate ester toxicity in the female reproductive system
    • Lovekamp-Swan T., and Davis B.J. Mechanisms of phthalate ester toxicity in the female reproductive system. Environ. Health Perspect. 111 2 (2003) 139-145
    • (2003) Environ. Health Perspect. , vol.111 , Issue.2 , pp. 139-145
    • Lovekamp-Swan, T.1    Davis, B.J.2
  • 29
    • 0032585881 scopus 로고    scopus 로고
    • trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals
    • Maloney E.K., and Waxman D.J. trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals. Toxicol. Appl. Pharmacol. 161 2 (1999) 209-218
    • (1999) Toxicol. Appl. Pharmacol. , vol.161 , Issue.2 , pp. 209-218
    • Maloney, E.K.1    Waxman, D.J.2
  • 31
    • 0035325333 scopus 로고    scopus 로고
    • Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?
    • Melnick R.L. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?. Environ. Health Perspect. 109 5 (2001) 437-442
    • (2001) Environ. Health Perspect. , vol.109 , Issue.5 , pp. 437-442
    • Melnick, R.L.1
  • 33
    • 0027993220 scopus 로고
    • The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo
    • Miyata K.S., McCaw S.E., Marcus S.L., Rachubinski R.A., and Capone J.P. The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo. Gene 148 2 (1994) 327-330
    • (1994) Gene , vol.148 , Issue.2 , pp. 327-330
    • Miyata, K.S.1    McCaw, S.E.2    Marcus, S.L.3    Rachubinski, R.A.4    Capone, J.P.5
  • 35
    • 0034021024 scopus 로고    scopus 로고
    • Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation
    • Mylchreest E., Wallace D.G., Cattley R.C., and Foster P.M. Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation. Toxicol. Sci. 55 1 (2000) 143-151
    • (2000) Toxicol. Sci. , vol.55 , Issue.1 , pp. 143-151
    • Mylchreest, E.1    Wallace, D.G.2    Cattley, R.C.3    Foster, P.M.4
  • 36
    • 2142698524 scopus 로고    scopus 로고
    • Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro
    • Okubo T., Suzuki T., Yokoyama Y., Kano K., and Kano I. Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro. Biol. Pharm. Bull. 26 8 (2003) 1219-1224
    • (2003) Biol. Pharm. Bull. , vol.26 , Issue.8 , pp. 1219-1224
    • Okubo, T.1    Suzuki, T.2    Yokoyama, Y.3    Kano, K.4    Kano, I.5
  • 37
    • 0035956850 scopus 로고    scopus 로고
    • Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
    • Park B.H., Vogelstein B., and Kinzler K.W. Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc. Natl. Acad. Sci. U.S.A. 98 5 (2001) 2598-2603
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , Issue.5 , pp. 2598-2603
    • Park, B.H.1    Vogelstein, B.2    Kinzler, K.W.3
  • 38
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
    • Peters J.M., Cattley R.C., and Gonzalez F.J. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 18 11 (1997) 2029-2033
    • (1997) Carcinogenesis , vol.18 , Issue.11 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 39
    • 0042335764 scopus 로고    scopus 로고
    • Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line
    • Pignatelli M., Cocca C., Santos A., and Perez-Castillo A. Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line. Oncogene 22 35 (2003) 5446-5450
    • (2003) Oncogene , vol.22 , Issue.35 , pp. 5446-5450
    • Pignatelli, M.1    Cocca, C.2    Santos, A.3    Perez-Castillo, A.4
  • 40
    • 0036865166 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism
    • Smith S.A. Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism. Biochem. Soc. Trans. 30 Pt 6 (2002) 1086-1090
    • (2002) Biochem. Soc. Trans. , vol.30 , Issue.PART 6 , pp. 1086-1090
    • Smith, S.A.1
  • 41
    • 0031601757 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptors
    • Sorensen H.N., Treuter E., and Gustafsson J.A. Regulation of peroxisome proliferator-activated receptors. Vitam. Horm. 54 (1998) 121-166
    • (1998) Vitam. Horm. , vol.54 , pp. 121-166
    • Sorensen, H.N.1    Treuter, E.2    Gustafsson, J.A.3
  • 43
    • 0036256981 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor β expression in the human breast epithelial cell lines of tumorigenic and non-tumorigenic origin
    • Suchanek K.M., May F.J., Lee W.J., Holman N.A., and Roberts-Thomson S.J. Peroxisome proliferator-activated receptor β expression in the human breast epithelial cell lines of tumorigenic and non-tumorigenic origin. Int. J. Biochem. Cell Biol. 34 9 (2002) 1051-1058
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , Issue.9 , pp. 1051-1058
    • Suchanek, K.M.1    May, F.J.2    Lee, W.J.3    Holman, N.A.4    Roberts-Thomson, S.J.5
  • 47
    • 0242443317 scopus 로고    scopus 로고
    • Expression of steroid receptor coactivators and corepressors in human endometrial hyperplasia and carcinoma with relevance to steroid receptors and Ki-67 expression
    • Uchikawa J., Shiozawa T., Shih H.C., Miyamoto T., Feng Y.Z., Kashima H., Oka K., and Konishi I. Expression of steroid receptor coactivators and corepressors in human endometrial hyperplasia and carcinoma with relevance to steroid receptors and Ki-67 expression. Cancer 98 10 (2003) 2207-2213
    • (2003) Cancer , vol.98 , Issue.10 , pp. 2207-2213
    • Uchikawa, J.1    Shiozawa, T.2    Shih, H.C.3    Miyamoto, T.4    Feng, Y.Z.5    Kashima, H.6    Oka, K.7    Konishi, I.8
  • 48
    • 0023524992 scopus 로고
    • Diethylhexylphthalate as an environmental contaminant-a review
    • Wams T.J. Diethylhexylphthalate as an environmental contaminant-a review. Sci. Total Environ. 66 (1987) 1-16
    • (1987) Sci. Total Environ. , vol.66 , pp. 1-16
    • Wams, T.J.1
  • 49
    • 0031969263 scopus 로고    scopus 로고
    • Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice
    • Ward J.M., Peters J.M., Perella C.M., and Gonzalez F.J. Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice. Toxicol. Pathol. 26 2 (1998) 240-246
    • (1998) Toxicol. Pathol. , vol.26 , Issue.2 , pp. 240-246
    • Ward, J.M.1    Peters, J.M.2    Perella, C.M.3    Gonzalez, F.J.4
  • 50
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
    • Willson T.M., et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J. Med. Chem. 39 3 (1996) 665-668
    • (1996) J. Med. Chem. , vol.39 , Issue.3 , pp. 665-668
    • Willson, T.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.