Rational design approaches to chemical libraries for hit identification

Current Drug Discovery Technologies

Volumn 3, Issue 1, 2006, Pages 49-65

  Balakin, Konstantin V ^a   Kozintsev, Alexander V ^a   Kiselyov, Alex S ^a   Savchuk, Nikolay P ^a  

^a CHEMDIV INC   (United States)

Author keywords

Combinatorial library design; High throughput screening; Hit identification; Informative library design; Pharmacophores; Structure based design; Topological descriptors; Virtual screening

Indexed keywords

BENZODIAZEPINE DERIVATIVE; LIGAND; RECEPTOR;

ALGORITHM; COMBINATORIAL LIBRARY; COMPUTER PROGRAM; DRUG DESIGN; HIGH THROUGHPUT SCREENING; METHODOLOGY; MOLECULAR LIBRARY; MOLECULE; PHARMACOPHORE; PRIORITY JOURNAL; REVIEW;

COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTATIONAL BIOLOGY; DRUG DESIGN; MODELS, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645807414     PISSN: 15701638     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016306776637564     Document Type: Review

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