Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history

PLoS Genetics

Volumn 2, Issue 1, 2006, Pages 81-92

  Traherne, James A ^a   Horton, Roger ^b   Roberts, Anne N ^a   Miretti, Marcos M ^b   Hurles, Matthew E ^b   Stewart, C Andrew ^a   Ashurst, Jennifer L ^b   Atrazhev, Alexey M ^c   Coggill, Penny ^b   Palmer, Sophie ^b   Almeida, Jeff ^b   Sims, Sarah ^b   Wilming, Laurens G ^b   Rogers, Jane ^b   De Jong, Pieter J ^d   Carrington, Mary ^e   Elliott, John F ^c   Sawcer, Stephen ^f   Todd, John A ^a   Trowsdale, John ^a   Beck, Stephan ^b   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF ALBERTA   (Canada)

^d CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; HLA DR3 ANTIGEN;

ALLELE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CELL LINE; DISEASE ASSOCIATION; GENE LOCUS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR CLONING; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMOSOME MAP; DNA SEQUENCE; GENETIC RECOMBINATION; GENETICS; MOLECULAR EVOLUTION;

BACTERIA (MICROORGANISMS);

CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CLONING, MOLECULAR; EVOLUTION, MOLECULAR; HAPLOTYPES; HLA-DR ANTIGENS; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

EID: 33645775299     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020009     Document Type: Article

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