메뉴 건너뛰기




Volumn 8, Issue 1, 2000, Pages 33-41

A linkage disequilibrium map of the MHC region based on the analysis of 14 loci haplotypes in 50 French families

Author keywords

CEPH families; French population; HLA haplotypes; Linkage disequilibrium; MHC; Population genetics

Indexed keywords

HLA A ANTIGEN;

EID: 17644449674     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200391     Document Type: Article
Times cited : (64)

References (67)
  • 1
    • 0003051762 scopus 로고    scopus 로고
    • The human major histocompatibility complex
    • Campbell RD, Trowsdale J: The human major histocompatibility complex. Immunol Today 1997; 18: 1.
    • (1997) Immunol Today , vol.18 , pp. 1
    • Campbell, R.D.1    Trowsdale, J.2
  • 2
    • 8044253412 scopus 로고    scopus 로고
    • Nomenclature for factors of the HLA system, 1996
    • Bodmer JG, Marsh SGE, Albert ED et al: Nomenclature for factors of the HLA system, 1996. Tissue Antigens 1997; 49: 297-321.
    • (1997) Tissue Antigens , vol.49 , pp. 297-321
    • Bodmer, J.G.1    Marsh, S.G.E.2    Albert, E.D.3
  • 3
    • 0018121719 scopus 로고
    • A haplotype study of HLA complex with special reference to the HLA-DR series and to Bf, C2, and Glyoxylase I polymorphisms
    • Dausset J, Legrand L, Lepage V et al: A haplotype study of HLA complex with special reference to the HLA-DR series and to Bf, C2, and Glyoxylase I polymorphisms. Tissue Antigens 1978; 12: 297-307.
    • (1978) Tissue Antigens , vol.12 , pp. 297-307
    • Dausset, J.1    Legrand, L.2    Lepage, V.3
  • 4
    • 0016176701 scopus 로고
    • Human migrations and linkage disequilibrium of HLA system
    • Degos L, Dausset J: Human migrations and linkage disequilibrium of HLA system. Immunogenet 1974; 3: 195-210.
    • (1974) Immunogenet , vol.3 , pp. 195-210
    • Degos, L.1    Dausset, J.2
  • 6
    • 0001924594 scopus 로고
    • Estimation of allele and haplotype frequencies for HLA and complement loci
    • Tsuji K, Aizawa M, Sasazuki T (eds). Oxford University Press: Oxford
    • Imanishi T, Akaza T, Kimura A, Tokunaga K, Gojobori T: Estimation of allele and haplotype frequencies for HLA and complement loci. In: Tsuji K, Aizawa M, Sasazuki T (eds). HLA 1991. Oxford University Press: Oxford, 1992, vol 1, pp 76-79.
    • (1992) HLA 1991 , vol.1 , pp. 76-79
    • Imanishi, T.1    Akaza, T.2    Kimura, A.3    Tokunaga, K.4    Gojobori, T.5
  • 7
    • 0026536466 scopus 로고
    • Sequence differences between HLA-B and TNF distinguish different MHC ancestral haplotypes
    • Abraham LJ, Leelayuwat C, Grimsley G et al: Sequence differences between HLA-B and TNF distinguish different MHC ancestral haplotypes. Tissue Antigens 1992; 39: 117-121.
    • (1992) Tissue Antigens , vol.39 , pp. 117-121
    • Abraham, L.J.1    Leelayuwat, C.2    Grimsley, G.3
  • 9
    • 0023430504 scopus 로고
    • Gametic disequilibrium measures: Proceed with caution
    • Hedrick PW: Gametic disequilibrium measures: proceed with caution. Genetics 1987; 117: 331-341.
    • (1987) Genetics , vol.117 , pp. 331-341
    • Hedrick, P.W.1
  • 10
    • 0023796209 scopus 로고    scopus 로고
    • On measures of gametic disequilibrium
    • Lewontin RC: On measures of gametic disequilibrium. Genetics 1998; 120: 849-852.
    • (1998) Genetics , vol.120 , pp. 849-852
    • Lewontin, R.C.1
  • 11
    • 0026546828 scopus 로고
    • Polymorphism, recombination, and linkage disequilibrium within the HLA class II region
    • Begovich AB, McClure GR, Suraj VC et al: Polymorphism, recombination, and linkage disequilibrium within the HLA class II region. J Immunol 1992; 148: 249-258.
    • (1992) J Immunol , vol.148 , pp. 249-258
    • Begovich, A.B.1    McClure, G.R.2    Suraj, V.C.3
  • 12
    • 0027943066 scopus 로고
    • Major histocompatibility complex class II haplotypes and linkage disequilibrium values observed in the CEPH families
    • Carrington M, Stephens JC, Klitz W, Begovich AB, Erlich HA, Mann D: Major histocompatibility complex class II haplotypes and linkage disequilibrium values observed in the CEPH families. Hum Immunol 1994; 41: 234-240.
    • (1994) Hum Immunol , vol.41 , pp. 234-240
    • Carrington, M.1    Stephens, J.C.2    Klitz, W.3    Begovich, A.B.4    Erlich, H.A.5    Mann, D.6
  • 13
    • 0028811072 scopus 로고
    • Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region
    • Klitz W, Stephens C, Grote M, Carrington M: Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region. Am J Hum Genet 1995; 57: 1436-1444.
    • (1995) Am J Hum Genet , vol.57 , pp. 1436-1444
    • Klitz, W.1    Stephens, C.2    Grote, M.3    Carrington, M.4
  • 14
    • 0029057472 scopus 로고
    • Molecular mapping of a recombination hotspot located in the second intron of the human TAP2 locus
    • Cullen M, Erlich H, Klitz W, Carrington M: Molecular mapping of a recombination hotspot located in the second intron of the human TAP2 locus. Am J Hum Genet 1995; 56: 1350-1358.
    • (1995) Am J Hum Genet , vol.56 , pp. 1350-1358
    • Cullen, M.1    Erlich, H.2    Klitz, W.3    Carrington, M.4
  • 15
    • 0031025043 scopus 로고    scopus 로고
    • Characterization of recombination in the HLA class II region
    • Cullen M, Noble J, Erlich H et al: Characterization of recombination in the HLA class II region. Am J Hum Genet 1997; 60: 397-407.
    • (1997) Am J Hum Genet , vol.60 , pp. 397-407
    • Cullen, M.1    Noble, J.2    Erlich, H.3
  • 16
    • 0028911335 scopus 로고
    • Recombination rates across the HLa complex: Use of microsatellites as a rapid screen for recombinant chromosomes
    • Martin M, Mann D, Carrington M: Recombination rates across the HLA complex: use of microsatellites as a rapid screen for recombinant chromosomes. Hum Mol Genet 1995; 4: 423-428.
    • (1995) Hum Mol Genet , vol.4 , pp. 423-428
    • Martin, M.1    Mann, D.2    Carrington, M.3
  • 17
    • 0031409270 scopus 로고    scopus 로고
    • Genetic variability and linkage disequilibrium within the DP region in the CEPH families
    • Moonsamy PV, Klitz W, Tilanus MG, Begovich AB: Genetic variability and linkage disequilibrium within the DP region in the CEPH families. Hum Immunol 1997; 58: 112-121.
    • (1997) Hum Immunol , vol.58 , pp. 112-121
    • Moonsamy, P.V.1    Klitz, W.2    Tilanus, M.G.3    Begovich, A.B.4
  • 18
    • 0014351929 scopus 로고
    • Serotyping for homotransplantation. Refinement of microdroplet lymphocyte cytotoxicity test
    • Mittal KK, Mickey MR, Singal DP, Terasaki PI: Serotyping for homotransplantation. Refinement of microdroplet lymphocyte cytotoxicity test. Transplant 1968; 6: 913-927.
    • (1968) Transplant , vol.6 , pp. 913-927
    • Mittal, K.K.1    Mickey, M.R.2    Singal, D.P.3    Terasaki, P.I.4
  • 19
    • 0007753537 scopus 로고
    • Technique de recherche des anticorps lymophocytotoxiques et determination des groupes tissulaires HLA
    • Allagille D (ed). Flammarion Médecine-Sciences: Paris
    • Colombani J, Hors J: Technique de recherche des anticorps lymophocytotoxiques et determination des groupes tissulaires HLA. In: Allagille D (ed). Techniques en Hématologie. Flammarion Médecine-Sciences: Paris, 1972, pp 251-254.
    • (1972) Techniques en Hématologie , pp. 251-254
    • Colombani, J.1    Hors, J.2
  • 21
    • 0020575713 scopus 로고
    • Determination of the second component of C' by electroimmunoassay in sera from patients ' with systemic lupus erythematosis
    • Ueda A, Kusabat T, Yanase T: Determination of the second component of C' by electroimmunoassay in sera from patients ' with systemic lupus erythematosis. Clin Exp Immunol 1983; 53: 217-224.
    • (1983) Clin Exp Immunol , vol.53 , pp. 217-224
    • Ueda, A.1    Kusabat, T.2    Yanase, T.3
  • 22
    • 0016248833 scopus 로고
    • A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement
    • Gaither TA, Ailing DW, Franck MM: A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement. J Immunol 1974; 113: 574-583.
    • (1974) J Immunol , vol.113 , pp. 574-583
    • Gaither, T.A.1    Ailing, D.W.2    Franck, M.M.3
  • 23
    • 0015266012 scopus 로고
    • Genetic polymorphism in human glycine rich B glycoprotein
    • Alper CA, Boenisch T, Watson L: Genetic polymorphism in human glycine rich B glycoprotein. J Exp Med 1972; 135: 68-80.
    • (1972) J Exp Med , vol.135 , pp. 68-80
    • Alper, C.A.1    Boenisch, T.2    Watson, L.3
  • 24
    • 0025914603 scopus 로고
    • DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene
    • Nedospasov SA, Udalova IA, Kuprash DV, Turetskaya RL: DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene. J Immunol 1991; 147: 1053-1059.
    • (1991) J Immunol , vol.147 , pp. 1053-1059
    • Nedospasov, S.A.1    Udalova, I.A.2    Kuprash, D.V.3    Turetskaya, R.L.4
  • 26
    • 0026689178 scopus 로고
    • Performing the exact test of Hardy-Weinberg proportion for multiple alleles
    • Guo S, Thompson E: Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 1992; 48: 361-372.
    • (1992) Biometrics , vol.48 , pp. 361-372
    • Guo, S.1    Thompson, E.2
  • 27
    • 0029178096 scopus 로고
    • An exact test for population differentiation
    • Raymond M, Rousset F: An exact test for population differentiation. Evolution 1995; 49: 1280-1283.
    • (1995) Evolution , vol.49 , pp. 1280-1283
    • Raymond, M.1    Rousset, F.2
  • 28
    • 0028333697 scopus 로고
    • Linkage disequilibrium in growing and stable populations
    • Slatkin M: Linkage disequilibrium in growing and stable populations. Genetics 1994; 137: 331-336.
    • (1994) Genetics , vol.137 , pp. 331-336
    • Slatkin, M.1
  • 30
    • 0017886236 scopus 로고
    • The homozygosity test of neutrality
    • Watterson GA: The homozygosity test of neutrality. Genetics 1978; 88: 405-417.
    • (1978) Genetics , vol.88 , pp. 405-417
    • Watterson, G.A.1
  • 31
    • 0022590865 scopus 로고
    • The homozygosity test after a change in population size
    • Watterson GA: The homozygosity test after a change in population size. Genetics 1986; 112: 899-907.
    • (1986) Genetics , vol.112 , pp. 899-907
    • Watterson, G.A.1
  • 32
    • 0015310384 scopus 로고
    • The sampling theory of selectivity neutral alleles
    • Ewens WJ: The sampling theory of selectivity neutral alleles. Theoret Pop Biol 1972; 3: 87-112.
    • (1972) Theoret Pop Biol , vol.3 , pp. 87-112
    • Ewens, W.J.1
  • 34
    • 0004283639 scopus 로고    scopus 로고
    • UCLA Tissue Typing Laboratory: Los Angeles
    • Terasaki PI, Gjertson DW (eds). HLA 1997.UCLA Tissue Typing Laboratory: Los Angeles, 1997.
    • (1997) HLA 1997
    • Terasaki, P.I.1    Gjertson, D.W.2
  • 35
    • 0031179347 scopus 로고    scopus 로고
    • High resolution of HLA-C typing by PCR-SSP: Identification of allelic frequencies and linkage disequilibrium in 604 unrelated random UK Caucasoids and a comparison with serology
    • Bunce M, Barnardo MCNM, Procter J, Marsh SGE, Vilches C, Welsh KI: High resolution of HLA-C typing by PCR-SSP: identification of allelic frequencies and linkage disequilibrium in 604 unrelated random UK Caucasoids and a comparison with serology. Tissue Antigens 1997; 50: 100-111.
    • (1997) Tissue Antigens , vol.50 , pp. 100-111
    • Bunce, M.1    Barnardo, M.C.N.M.2    Procter, J.3    Marsh, S.G.E.4    Vilches, C.5    Welsh, K.I.6
  • 36
    • 0027765609 scopus 로고
    • Tumor necrosis factor microsatellites in four European populations
    • Crouau-Roy B, Briant L, Bouissou C et al: Tumor necrosis factor microsatellites in four European populations. Hum Immunol 1993; 38: 213-216.
    • (1993) Hum Immunol , vol.38 , pp. 213-216
    • Crouau-Roy, B.1    Briant, L.2    Bouissou, C.3
  • 38
    • 0031467672 scopus 로고    scopus 로고
    • First report of recombination between the HLA-DR and HLA-DQ loci within a family
    • Sullivan KA, Wolfe MA, Lopez M, Jaspan JB, Bryer-Ash M: First report of recombination between the HLA-DR and HLA-DQ loci within a family. Hum Immunol 1997; 57: 37-43.
    • (1997) Hum Immunol , vol.57 , pp. 37-43
    • Sullivan, K.A.1    Wolfe, M.A.2    Lopez, M.3    Jaspan, J.B.4    Bryer-Ash, M.5
  • 40
    • 0030977020 scopus 로고    scopus 로고
    • Diversity associated with the second expressed HLA-DRB locus in the human population
    • Robbins F, Hurley CK, Tang T et al: Diversity associated with the second expressed HLA-DRB locus in the human population. Immunogenet 1997; 46: 104-110.
    • (1997) Immunogenet , vol.46 , pp. 104-110
    • Robbins, F.1    Hurley, C.K.2    Tang, T.3
  • 41
    • 0029070889 scopus 로고
    • HLA class II linkage disequilibrium and haplotype evolution in the Cayapa Indians of Ecuador
    • Trachtenberg EA, Erlich HA, Rickards O, DeStefano GF, Klitz W: HLA class II linkage disequilibrium and haplotype evolution in the Cayapa Indians of Ecuador. Am J Hum Genet 1995; 57: 415-424.
    • (1995) Am J Hum Genet , vol.57 , pp. 415-424
    • Trachtenberg, E.A.1    Erlich, H.A.2    Rickards, O.3    DeStefano, G.F.4    Klitz, W.5
  • 42
    • 0027508146 scopus 로고
    • Absence of strong HLA-DR/DQ-DP linkage disequilibrium in the British and French Canadian Caucasoid populations
    • Howell WM, Evans PR, Devereux SA, Sage DA, Smoth JL, Haegert DG: Absence of strong HLA-DR/DQ-DP linkage disequilibrium in the British and French Canadian Caucasoid populations. Europ J Immunogenet 1993; 20: 363-371.
    • (1993) Europ J Immunogenet , vol.20 , pp. 363-371
    • Howell, W.M.1    Evans, P.R.2    Devereux, S.A.3    Sage, D.A.4    Smoth, J.L.5    Haegert, D.G.6
  • 43
    • 0028266123 scopus 로고
    • Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region
    • Jorde LB, Watkins WS, Carlson M et al: Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region. Am J Hum Genet 1994; 54: 884-898.
    • (1994) Am J Hum Genet , vol.54 , pp. 884-898
    • Jorde, L.B.1    Watkins, W.S.2    Carlson, M.3
  • 45
    • 0027749428 scopus 로고
    • Histocompatibility matching for bone marrow transplantation donor-recipient pairs in the 4AOHW cell panel
    • Christiansen FT, Tay G, Smith LK et al: Histocompatibility matching for bone marrow transplantation donor-recipient pairs in the 4AOHW cell panel. Hum Immunol 1993; 38: 42-51.
    • (1993) Hum Immunol , vol.38 , pp. 42-51
    • Christiansen, F.T.1    Tay, G.2    Smith, L.K.3
  • 48
    • 0025817428 scopus 로고
    • MHC class-II molecules and autoimmunity
    • Nepom GT, Erlich H: MHC class-II molecules and autoimmunity. Annu Rev Immunol 1991; 9: 493-525.
    • (1991) Annu Rev Immunol , vol.9 , pp. 493-525
    • Nepom, G.T.1    Erlich, H.2
  • 49
    • 0030249137 scopus 로고    scopus 로고
    • Distribution of HLA class II alleles and haplotypes in insulin-dependent Moroccan diabetics
    • Izaabel H, Garchon H-J, Beaurin G et al: Distribution of HLA class II alleles and haplotypes in insulin-dependent Moroccan diabetics. Hum Immunol 1996; 49: 137-143.
    • (1996) Hum Immunol , vol.49 , pp. 137-143
    • Izaabel, H.1    Garchon, H.-J.2    Beaurin, G.3
  • 50
    • 0023764283 scopus 로고
    • Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
    • Hughes AL, Nei M: Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection. Nature 1988; 335: 167-170.
    • (1988) Nature , vol.335 , pp. 167-170
    • Hughes, A.L.1    Nei, M.2
  • 51
    • 0040771786 scopus 로고
    • Nucleotide substitution at major histocompatibility complex class II loci: Evidence for overdominant selection
    • Hughes AL, Nei M: Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection. Proc Natl Acad Sci USA 1989; 86: 958-962.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 958-962
    • Hughes, A.L.1    Nei, M.2
  • 52
    • 0029088874 scopus 로고
    • Natural selection on the peptide-binding regions of major histocompatibility complex molecules
    • Hughes AL, Hughes MK: Natural selection on the peptide-binding regions of major histocompatibility complex molecules. Immunogenet 1995; 42: 233-243.
    • (1995) Immunogenet , vol.42 , pp. 233-243
    • Hughes, A.L.1    Hughes, M.K.2
  • 53
    • 0028361982 scopus 로고
    • Intensity of natural selection at the major histocompatibility complex loci in primates
    • Satta Y, O'hUigin C, Takahata N, Klein J: Intensity of natural selection at the major histocompatibility complex loci in primates. Proc Natl Acad Sci USA 1994; 91: 7184-7188.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7184-7188
    • Satta, Y.1    O'HUigin, C.2    Takahata, N.3    Klein, J.4
  • 54
    • 0025255468 scopus 로고
    • Allelic geneaology under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci
    • Takahata N, Nei M: Allelic geneaology under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics 1990; 124: 967-978.
    • (1990) Genetics , vol.124 , pp. 967-978
    • Takahata, N.1    Nei, M.2
  • 55
    • 0013282068 scopus 로고
    • Trans-species polymorphism of HLA molecules, founder principle, and human evolution
    • Klein J, Klein D (eds). Springer-Verlag: Heidelberg
    • Takahata N: Trans-species polymorphism of HLA molecules, founder principle, and human evolution. In: Klein J, Klein D (eds). Molecular Evolution of the Major Histocompatibility Complex. Springer-Verlag: Heidelberg, 1991, pp 29-49.
    • (1991) Molecular Evolution of the Major Histocompatibility Complex , pp. 29-49
    • Takahata, N.1
  • 56
    • 0022968265 scopus 로고
    • Contrasting evolutionary histories among tightly linked HLA loci
    • Klitz W, Thomson G, Baur MP: Contrasting evolutionary histories among tightly linked HLA loci. Am J Hum Genet 1986; 39: 340-349.
    • (1986) Am J Hum Genet , vol.39 , pp. 340-349
    • Klitz, W.1    Thomson, G.2    Baur, M.P.3
  • 57
    • 0026768995 scopus 로고
    • HLA-DR polymorphism in a Senegalese Mandenka population: DNA oligotyping and population genetics of DRB1 specificities
    • Tiercy J-M, Sanchez-Mazas A, Excoffier L et al: HLA-DR polymorphism in a Senegalese Mandenka population: DNA oligotyping and population genetics of DRB1 specificities. Am J Hum Genet 1992; 51: 592-602.
    • (1992) Am J Hum Genet , vol.51 , pp. 592-602
    • Tiercy, J.-M.1    Sanchez-Mazas, A.2    Excoffier, L.3
  • 59
    • 0028242990 scopus 로고
    • HLA-DPB1 DNA polymorphism in the Swiss population: Linkage disequilibrium with other HLA loci and population genetic affinities
    • Grundschober C, Sanchez-Mazas A, Excoffier L, Langaney A, Jeannet M, Tiercy J-M: HLA-DPB1 DNA polymorphism in the Swiss population: linkage disequilibrium with other HLA loci and population genetic affinities. Eur J Immunogenet 1994; 21: 143-157.
    • (1994) Eur J Immunogenet , vol.21 , pp. 143-157
    • Grundschober, C.1    Sanchez-Mazas, A.2    Excoffier, L.3    Langaney, A.4    Jeannet, M.5    Tiercy, J.-M.6
  • 60
    • 0027989667 scopus 로고
    • Design and sample-size considerations in the detection of linkage disequilibrium with a disease locus
    • Olson JM, Wijsman EM: Design and sample-size considerations in the detection of linkage disequilibrium with a disease locus. Am J Hum Genet 1994; 55: 574-580.
    • (1994) Am J Hum Genet , vol.55 , pp. 574-580
    • Olson, J.M.1    Wijsman, E.M.2
  • 61
    • 0030827879 scopus 로고    scopus 로고
    • The effect of marker heterozygosity on the power to detect linkage disequilibrium
    • Ott J, Rabinowitz D: The effect of marker heterozygosity on the power to detect linkage disequilibrium. Genetics 1997; 147: 927-930.
    • (1997) Genetics , vol.147 , pp. 927-930
    • Ott, J.1    Rabinowitz, D.2
  • 62
    • 0030716298 scopus 로고    scopus 로고
    • The HLA A1-B8 haplotype extends 6Mb beyond HLA-A: Associations between HLA-A, B, F and 15 microsatellite markers
    • Worwood M, Raha Chowdhury R, Robson KJH, Pointon J, Shearman JD, Darke C: The HLA A1-B8 haplotype extends 6Mb beyond HLA-A: associations between HLA-A, B, F and 15 microsatellite markers. Tissue Antigens 1997; 50: 521-526.
    • (1997) Tissue Antigens , vol.50 , pp. 521-526
    • Worwood, M.1    Raha Chowdhury, R.2    Robson, K.J.H.3    Pointon, J.4    Shearman, J.D.5    Darke, C.6
  • 63
    • 9344224529 scopus 로고    scopus 로고
    • A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
    • Feder JN, Gnirke A, Thomas W et al: A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996; 13: 399-409.
    • (1996) Nat Genet , vol.13 , pp. 399-409
    • Feder, J.N.1    Gnirke, A.2    Thomas, W.3
  • 65
    • 0003808971 scopus 로고    scopus 로고
    • Human genetic variation and its impact on public health and medicine
    • Stearns SC (ed). Oxford University Press: Oxford
    • Hill AVS, Sanchez-Mazas A, Barbujani G et al: Human genetic variation and its impact on public health and medicine. In: Stearns SC (ed). Evolution in Health and Disease. Oxford University Press: Oxford, 1999, pp 62-74.
    • (1999) Evolution in Health and Disease , pp. 62-74
    • Hill, A.V.S.1    Sanchez-Mazas, A.2    Barbujani, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.