Melanocortin modulation of inflammatory cytokine and neuroendocrine responses to endotoxin in the monkey

Endocrinology

Volumn 147, Issue 4, 2006, Pages 1878-1883

  Vulliémoz, Nicolas R ^a   Xiao, Ennian ^a   Xia Zhang, Linna ^a   Ferin, Michel ^a   Wardlaw, Sharon L ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; CORTICOTROPIN; ENDOTOXIN; HORMONE RECEPTOR STIMULATING AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MELANOCORTIN; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; HYPOPHYSIS ADRENAL SYSTEM; MONKEY; NEUROENDOCRINE SYSTEM; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL;

ADRENOCORTICOTROPIC HORMONE; ALPHA-MSH; ANIMALS; CYTOKINES; FEMALE; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LIPOPOLYSACCHARIDES; MACACA MULATTA; MELANOCYTE-STIMULATING HORMONES; PITUITARY-ADRENAL SYSTEM; RECEPTORS, MELANOCORTIN;

EID: 33645528940     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-1430     Document Type: Article

References (41)

1. Catania A, Lipton JM 1993 α-Melanocyte stimulating hormone in the modulation of host reactions. Endocr Rev 14:564-576
2. Huang QH, Hruby VJ, Tatro JB 1998 Systemic α-MSH suppresses LPS fever via central melanocortin receptors independently of its suppression of corticosterone and IL-6 release. Am J Physiol 275:R524-R530
3. Daynes RA, Robertson BA, Cho BH, Burnham DK, Newton R 1987 α-Melanocyte-stimulating hormone exhibits target cell selectivity in its capacity to affect interleukin 1-inducible responses in vivo and in vitro. J Immunol 139:103-109
4. Weiss JM, Sundar SK, Cierpial MA, Ritchie JC 1991 Effects of interleukin-1 infused into brain are antagonized by α-MSH in a dose-dependent manner. Eur J Pharmacol. 192:177-179
5. Getting SJ, Gibbs L, Clark AJ, Flower RJ, Perretti M 1999 POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. J Immunol 162:7446-7453
6. Catania A, Gatti S, Colombo G, Lipton JM 2004 Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol Rev 56:1-29
7. Huang QH, Hruby VJ, Tatro JB 1999 Role of central melanocortins in endotoxin-induced anorexia. Am J Physiol 276:R864-R871
8. Manna SK, Aggarwal BB 1998 α-Melanocyte-stimulating hormone inhibits the nuclear transcription factor NF-κB activation induced by various inflammatory agents. J Immunol 161:2873-2880
9. Macaluso A, McCoy D, Ceriani G, Watanabe T, Biltz J, Catania A, Lipton JM 1994 Antiinflammatory influences of α-MSH molecules: central neurogenic and peripheral actions. J Neurosci 14:2377-2382
10. Bhardwaj RS, Schwarz A, Becher E, Mahnke K, Aragane Y, Schwarz T, Luger TA 1996 Pro-opiomelanocortin-derived peptides induce IL-10 production in human monocytes. J Immunol 156:2517-2521
11. Taherzadeh S, Sharma S, Chhajlani V, Gantz I, Rajora N, Demitri MT, Kelly L, Zhao H, Ichiyama T, Catania A, Lipton JM 1999 α-MSH and its receptors in regulation of tumor necrosis factor-α production by human monocyte/macrophages. Am J Physiol 276:R1289-R1294
12. Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M 2003 Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. J Immunol 170:3323-3330
13. Lam CW, Getting SJ 2004 Melanocortin receptor type 3 as a potential target for anti-inflammatory therapy. Curr Drug Targets Inflamm Allergy 3:311-315
14. Huang QH, Entwistle ML, Alvaro JD, Duman RS, Hruby VJ, Tatro JB 1997 Antipyretic role of endogenous melanocortins mediated by central melanocortin receptors during endotoxin-induced fever. J Neurosci 17:3343-3351
15. Papadopoulos AD, Wardlaw SL 1999 Endogenous α-MSH modulates the hypothalamic-pituitary-adrenal response to the cytokine interleukin-1β. J Neuroendocrinol 11:315-319
16. Xiao E, Xia-Zhang L, Vulliemoz NR, Ferin M, Wardlaw SL 2003 Agouti-related protein stimulates the hypothalamic-pituitary-adrenal (HPA) axis and enhances the HPA response to interleukin-1 in the primate. Endocrinology 144:1736-1741
17. Grieco P, Balse PM, Weinberg D, MacNeil T, Hruby VJ 2000 D-Amino acid scan of γ-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity. J Med Chem 43:4998-5002
18. Puder JJ, Freda PU, Goland RS, Wardlaw SL 2001 Estrogen modulates the hypothalamic-pituitary-adrenal and inflammatory cytokine responses to endotoxin in women. J Clin Endocrinol Metab 86:2403-2408
19. Xiao E, Xia-Zhang L, Ferin M, Wardlaw SL 2001 Differential effects of estradiol on the adrenocorticotropin responses to interleukin-6 and interleukin-1 in the monkey. Endocrinology 142:2736-2741
20. 2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors. J Med Chem 38:3454-3461
21. Xiao E, Xia-Zhang L, Vulliemoz NR, Ferin M, Wardlaw SL 2003 Leptin modulates inflammatory cytokine and neuroendocrine responses to endotoxin in the primate. Endocrinology 144:350-353
22. Landman RE, Puder JJ, Xiao E, Freda PU, Ferin M, Wardlaw SL 2003 Endotoxin stimulates leptin in the human and nonhuman primate. J Clin Endocrinol Metab 88:1285-1291
23. Xiao E, Xia L, Ferin M, Wardlaw SL 1999 Intracerebroventricular injection of interleukin-1 stimulates the release of high levels of interleukin-6 and interleukin-1 receptor antagonist into peripheral blood in the primate. J Neuroimmunol 97:70-76
24. Lotti T, Bianchi B, Ghersetich I, Brazzini B, Hercogova J 2002 Can the brain inhibit inflammation generated in the skin? The lesson of γ-melanocyte-stimulating hormone. Int J Dermatol 41:311-318
25. Shih ST, Khorram O, Lipton JM, McCann SM 1986 Central administration of α-MSH antiserum augments fever in the rabbit. Am J Physiol 250:R803-R806
26. Getting SJ, Allcock GH, Flower R, Perretti M 2001 Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties. J Leukocyte Biol 69:98-104
27. 1 receptors are constitutively expressed on leucocyte subpopulations with antigen presenting and cytotoxic functions. Clin Exp Immunol 126:441-446
28. Akbulut S, Byersdorfer CA, Larsen CP, Zimmer SL, Humphreys TD, Clarke BL 2001 Expression of the melanocortin 5 receptor on rat lymphocytes. Biochem Biophys Res Commun 281:1086-1092
29. Emeson RB, Eipper BA 1986 Characterization of pro-ACTH/endorphin-derived peptides in rat hypothalamus. J Neurosci 6:837-849
30. Smith AI, Funder JW 1988 Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues. Endocr Rev 9:159-179
31. Blalock JE 1999 Proopiomelanocortin and the immune-neuroendocrine connection. Ann NY Acad Sci 885:161-172
32. Lipton JM, Macaluso A, Hiltz ME, Catania A 1991 Central administration of the peptide α-MSH inhibits inflammation in the skin. Peptides 12:795-798
33. Marks DL, Butler AA, Turner R, Brookhart G, Cone RD 2003 Differential role of melanocortin receptor subtypes in cachexia. Endocrinology 144:1513-1523
34. Turnbull AV, Rivier CL 1999 Regulation of the hypothalamic-pituitary- adrenal axis by cytokines: actions and mechanisms of action. Physiol Rev 79:1-71
35. Shalts E, Feng YJ, Ferin M, Wardlaw SL 1992 α-Melanocyte- stimulating hormone antagonizes the neuroendocrine effects of corticotropin-releasing factor and interleukin-1α in the primate. Endocrinology 131:132-138
36. Lyson K, McCann SM 1993 α-Melanocyte-stimulating hormone abolishes IL-1- and IL-6-induced corticotropin-releasing factor release from the hypothalamus in vitro. Neuroendocrinology 58:191-195
37. Zelazowski P, Patchev VK, Zelazowska EB, Chrousos GP, Gold PW, Sternberg EM 1993 Release of hypothalamic corticotropin-releasing hormone and arginine-vasopressin by interleukin 1β and α MSH: studies in rats with different susceptibility to inflammatory disease. Brain Res 631:22-26
38. Ichiyama T, Sakai T, Catania A, Barsh GS, Furukawa S, Lipton JM 1999 Systemically administered α-melanocyte-stimulating peptides inhibit NF-κB activation in experimental brain inflammation. Brain Res 836:31-37
39. Scholzen TE, Sunderkotter C, Kalden DH, Brzoska T, Fastrich M, Fisbeck T, Armstrong CA, Ansel JC, Luger TA 2003 α-Melanocyte stimulating hormone prevents lipopolysaccharide-induced vasculitis by down-regulating endothelial cell adhesion molecule expression. Endocrinology 144:360-370
40. Taylor AW 2005 The immunomodulating neuropeptide α-melanocyte- stimulating hormone (α-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages. J Neuroimmunol 162:43-50
41. Star RA, Rajora N, Huang J, Stock RC, Catania A, Lipton JM 1995 Evidence of autocrine modulation of macrophage nitric oxide synthase by α-melanocyte-stimulating hormone. Proc Natl Acad Sci USA 92:8016-8020