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Volumn 17, Issue 2, 2006, Pages 139-151

Genetic variants predisposing to cardiovascular disease

Author keywords

Cardiovascular disease; Environment; Genetic

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANGIOTENSINOGEN; APOLIPOPROTEIN A5; APOLIPOPROTEIN E; APOLIPOPROTEIN M; ARYLDIALKYLPHOSPHATASE 1; DIMETHYLARGININASE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN CONVERTING ENZYME; GENE PRODUCT; LIPOPROTEIN LIPASE; LYMPHOTOXIN; MONOCYTE ENHANCER FACTOR 2A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHODIESTERASE IV; PROTEIN; PROTEIN ALOX5AP; UNCLASSIFIED DRUG;

EID: 33645509725     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mol.0000217895.67444.de     Document Type: Review
Times cited : (54)

References (130)
  • 1
    • 0037319447 scopus 로고    scopus 로고
    • Genetic and environment contributions to atherosclerosis phenotypes in men and women: Heritability of carotid intima-media thickness in the Framingham Heart Study
    • Fox CS, Polak JF, Chazaro I, et al. Genetic and environment contributions to atherosclerosis phenotypes in men and women: heritability of carotid intima-media thickness in the Framingham Heart Study. Stroke 2003; 34:397-401.
    • (2003) Stroke , vol.34 , pp. 397-401
    • Fox, C.S.1    Polak, J.F.2    Chazaro, I.3
  • 2
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 2004; 431:931-945.
    • (2004) Nature , vol.431 , pp. 931-945
  • 3
    • 27944462277 scopus 로고    scopus 로고
    • Genetic determinants of blood pressure regulation
    • Marteau JB, Zaiou M, Siest G, Visvikis-Siest S. Genetic determinants of blood pressure regulation. J Hypertension 2005; 23:2127-2143. The authors highlight the genetic basis of hypertension and discuss limitations to clinical applications of genotypic information in the diagnosis.
    • (2005) J Hypertension , vol.23 , pp. 2127-2143
    • Marteau, J.B.1    Zaiou, M.2    Siest, G.3    Visvikis-Siest, S.4
  • 4
    • 0032892245 scopus 로고    scopus 로고
    • Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: The British Regional Heart Study
    • Ebrahim S, Papacosta O, Whincup P, et al. Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study. Stroke 1999; 30:841-850.
    • (1999) Stroke , vol.30 , pp. 841-850
    • Ebrahim, S.1    Papacosta, O.2    Whincup, P.3
  • 5
    • 0029828316 scopus 로고    scopus 로고
    • Association between angiotensin converting enzyme gene polymorphism and carotid atherosclerosis
    • Kauma H, Paivansalo M, Savolainen MJ, et al. Association between angiotensin converting enzyme gene polymorphism and carotid atherosclerosis. J Hypertens 1996; 14:1183-1187.
    • (1996) J Hypertens , vol.14 , pp. 1183-1187
    • Kauma, H.1    Paivansalo, M.2    Savolainen, M.J.3
  • 6
    • 0033374852 scopus 로고    scopus 로고
    • Relationship of angiotensin-converting enzyme gene polymorphism to carotid wall thickness in middle-aged men
    • Huang XH, Loimaala A, Nenonen A, et al. Relationship of angiotensin-converting enzyme gene polymorphism to carotid wall thickness in middle-aged men. J Mol Med 1999; 77:853-858.
    • (1999) J Mol Med , vol.77 , pp. 853-858
    • Huang, X.H.1    Loimaala, A.2    Nenonen, A.3
  • 7
    • 0032807534 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population
    • Hung J, McQuillan BM, Nidorf M, et al. Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population. Arterioscler Thromb Vasc Biol 1999; 19:1969-1974.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1969-1974
    • Hung, J.1    McQuillan, B.M.2    Nidorf, M.3
  • 8
    • 1242337374 scopus 로고    scopus 로고
    • A study of gene-environment interaction on the gene for angiotensin converting enzyme: A combined functional and population based approach
    • Sayed-Tabatabaei FA, Schut AF, Hofman A, et al. A study of gene-environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach. J Med Genet 2004; 41:99-103.
    • (2004) J Med Genet , vol.41 , pp. 99-103
    • Sayed-Tabatabaei, F.A.1    Schut, A.F.2    Hofman, A.3
  • 9
    • 13244255684 scopus 로고    scopus 로고
    • Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: The Rotterdam Study
    • Sayed-Tabatabaei FA, Schut AF, Vasquez AA, et al. Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study. J Med Genet 2005; 42:26-30.
    • (2005) J Med Genet , vol.42 , pp. 26-30
    • Sayed-Tabatabaei, F.A.1    Schut, A.F.2    Vasquez, A.A.3
  • 10
    • 0026675062 scopus 로고
    • Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
    • Cambien F, Poirier O, Lecerf L, et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359:641-644.
    • (1992) Nature , vol.359 , pp. 641-644
    • Cambien, F.1    Poirier, O.2    Lecerf, L.3
  • 11
    • 0037409232 scopus 로고    scopus 로고
    • Polymorphisms in the RAS and cardiac function
    • van Berlo JH, Pinto YM. Polymorphisms in the RAS and cardiac function. Int J Biochem Cell Biol 2003; 35:932-943.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 932-943
    • Van Berlo, J.H.1    Pinto, Y.M.2
  • 12
    • 0141678882 scopus 로고    scopus 로고
    • Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis
    • Ye S, Dhillon S, Seear R, et al. Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis. Heart 2003; 89:1195-1199.
    • (2003) Heart , vol.89 , pp. 1195-1199
    • Ye, S.1    Dhillon, S.2    Seear, R.3
  • 13
    • 4644363099 scopus 로고    scopus 로고
    • Possible synergic effect of angiotensin-I converting enzyme gene insertion/deletion polymorphism and angiotensin-II type-1 receptor 1166A/C gene polymorphism on ischemic heart disease in patients with Kawasaki disease
    • Fukazawa R, Sonobe T, Hamamoto K, et al. Possible synergic effect of angiotensin-I converting enzyme gene insertion/deletion polymorphism and angiotensin-II type-1 receptor 1166A/C gene polymorphism on ischemic heart disease in patients with Kawasaki disease. Pediatr Res 2004; 56:597-601.
    • (2004) Pediatr Res , vol.56 , pp. 597-601
    • Fukazawa, R.1    Sonobe, T.2    Hamamoto, K.3
  • 14
    • 12344315341 scopus 로고    scopus 로고
    • Carotid artery intima-media thickness and angiotensin-converting enzyme gene polymorphism in the offspring of parents with premature stroke
    • Varda NM, Peterlin B, Bradac SU, Gregoric A. Carotid artery intima-media thickness and angiotensin-converting enzyme gene polymorphism in the offspring of parents with premature stroke. Acta Paediatr 2005; 94:33-37.
    • (2005) Acta Paediatr , vol.94 , pp. 33-37
    • Varda, N.M.1    Peterlin, B.2    Bradac, S.U.3    Gregoric, A.4
  • 15
    • 0003571561 scopus 로고    scopus 로고
    • Fauci A, Braunwald E, Isselbacher K, et al. editors. New York McGraw-Hill
    • Fauci A, Braunwald E, Isselbacher K, et al. editors. Harrison's principles of internal medicine. 14th ed. New York McGraw-Hill; 1998.
    • (1998) Harrison's Principles of Internal Medicine. 14th Ed.
  • 16
    • 0028944631 scopus 로고
    • Genetic control of blood pressure and the angiotensinogen locus
    • U S A
    • Kim HS, Krege JH, Kluckman KD, et al. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci U S A 1995; 92:2735-2739.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 2735-2739
    • Kim, H.S.1    Krege, J.H.2    Kluckman, K.D.3
  • 17
    • 0026669336 scopus 로고
    • Molecular basis of human hypertension: Role of angiotensinogen
    • Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992; 71:169-180.
    • (1992) Cell , vol.71 , pp. 169-180
    • Jeunemaitre, X.1    Soubrier, F.2    Kotelevtsev, Y.V.3
  • 18
    • 0032915912 scopus 로고    scopus 로고
    • Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
    • Winkelmann BR, Russ AP, Nauck M, et al. Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease. Am Heart J 1999; 137:698-705.
    • (1999) Am Heart J , vol.137 , pp. 698-705
    • Winkelmann, B.R.1    Russ, A.P.2    Nauck, M.3
  • 19
    • 0038796602 scopus 로고    scopus 로고
    • Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease
    • Sethi AA, Nordestgaard BG, Gronholdt ML, et al. Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease. Hypertension 2003; 41:1202-1211.
    • (2003) Hypertension , vol.41 , pp. 1202-1211
    • Sethi, A.A.1    Nordestgaard, B.G.2    Gronholdt, M.L.3
  • 20
    • 0342526616 scopus 로고    scopus 로고
    • Angiotensinogen mutations and risk for ischemic heart disease, myocardial infarction, and ischemic cerebrovascular disease: Six case-control studies from the Copenhagen City Heart Study
    • Sethi AA, Tybjaerg-Hansen A, Gronholdt ML, et al. Angiotensinogen mutations and risk for ischemic heart disease, myocardial infarction, and ischemic cerebrovascular disease: six case-control studies from the Copenhagen City Heart Study. Ann Intern Med 2001; 134:941-954.
    • (2001) Ann Intern Med , vol.134 , pp. 941-954
    • Sethi, A.A.1    Tybjaerg-Hansen, A.2    Gronholdt, M.L.3
  • 21
    • 0037771145 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: A meta-analysis
    • Sethi AA, Nordestgaard BG, Tybjaerg-Hansen A. Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis. Arterioscler Thromb Vasc Biol 2003; 23:1269-1275.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1269-1275
    • Sethi, A.A.1    Nordestgaard, B.G.2    Tybjaerg-Hansen, A.3
  • 22
    • 0034749041 scopus 로고    scopus 로고
    • Polymorphisms in the angiotensinogen gene are associated with carotid intimal-medial thickening in females from a community-based population
    • Chapman CM, Palmer LJ, McQuillan BM, et al. Polymorphisms in the angiotensinogen gene are associated with carotid intimal-medial thickening in females from a community-based population. Atherosclerosis 2001; 159:209-217.
    • (2001) Atherosclerosis , vol.159 , pp. 209-217
    • Chapman, C.M.1    Palmer, L.J.2    McQuillan, B.M.3
  • 23
    • 20244376442 scopus 로고    scopus 로고
    • Cardiovascular phenotype of young adults and angiotensinogen alleles
    • Sarzani R, Dessi-Fulgheri P, Mazzara D, et al. Cardiovascular phenotype of young adults and angiotensinogen alleles. J Hypertens 2001; 19:2171-2178.
    • (2001) J Hypertens , vol.19 , pp. 2171-2178
    • Sarzani, R.1    Dessi-Fulgheri, P.2    Mazzara, D.3
  • 24
    • 0242637502 scopus 로고    scopus 로고
    • Angiotensinogen gene M235T polymorphism and reduction in wall thickness in response to antihypertensive treatment
    • Lond
    • Bozec E, Fassot C, Tropeano AI, et al. Angiotensinogen gene M235T polymorphism and reduction in wall thickness in response to antihypertensive treatment. Clin Sci (Lond) 2003; 105:637-644.
    • (2003) Clin Sci , vol.105 , pp. 637-644
    • Bozec, E.1    Fassot, C.2    Tropeano, A.I.3
  • 25
    • 27744482456 scopus 로고    scopus 로고
    • Angiotensinogen M235T polymorphism is associated with coronary artery disease severity
    • Lanz JR, Pereira AC, Lemos PA, et al. Angiotensinogen M235T polymorphism is associated with coronary artery disease severity. Clin Chim Acta 2005; 362:176-181.
    • (2005) Clin Chim Acta , vol.362 , pp. 176-181
    • Lanz, J.R.1    Pereira, A.C.2    Lemos, P.A.3
  • 26
    • 16844373836 scopus 로고    scopus 로고
    • Association of angiotensinogen haplotypes with angiotensinogen levels but not with blood pressure or coronary artery disease: The Ludwigshafen Risk and Cardiovascular Health Study
    • Renner W, Nauck M, Winkelmann BR, et al. Association of angiotensinogen haplotypes with angiotensinogen levels but not with blood pressure or coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study. J Mol Med 2005; 83:235-239.
    • (2005) J Mol Med , vol.83 , pp. 235-239
    • Renner, W.1    Nauck, M.2    Winkelmann, B.R.3
  • 27
    • 0035006125 scopus 로고    scopus 로고
    • APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort)
    • Pallaud C, Sass C, Zannad F, et al. APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort). Clin Genet 2001; 59:316-324.
    • (2001) Clin Genet , vol.59 , pp. 316-324
    • Pallaud, C.1    Sass, C.2    Zannad, F.3
  • 28
    • 0033545888 scopus 로고    scopus 로고
    • Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
    • McQuillan BM, Beilby JP, Nidorf M, et al. Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS) Circulation 1999; 99:2383-2388.
    • (1999) Circulation , vol.99 , pp. 2383-2388
    • McQuillan, B.M.1    Beilby, J.P.2    Nidorf, M.3
  • 29
    • 0037477386 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population
    • Inamoto N, Katsuya T, Kokubo Y, et al. Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population. Stroke 2003; 34:1628-1633.
    • (2003) Stroke , vol.34 , pp. 1628-1633
    • Inamoto, N.1    Katsuya, T.2    Kokubo, Y.3
  • 30
    • 0042919553 scopus 로고    scopus 로고
    • Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: A Multicenter Case-Control Study in China
    • Li Z, Sun L, Zhang H, et al. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China. Stroke 2003; 34:2085-2090.
    • (2003) Stroke , vol.34 , pp. 2085-2090
    • Li, Z.1    Sun, L.2    Zhang, H.3
  • 31
    • 3042642830 scopus 로고    scopus 로고
    • The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor
    • Jiang S, Hsu YH, Xu X, et al. The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. Thromb Res 2004; 113:361-369.
    • (2004) Thromb Res , vol.113 , pp. 361-369
    • Jiang, S.1    Hsu, Y.H.2    Xu, X.3
  • 32
    • 0142219380 scopus 로고    scopus 로고
    • Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level
    • Spotila LD, Jacques PF, Berger PB, et al. Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level. Am J Epidemiol 2003; 158:871-877.
    • (2003) Am J Epidemiol , vol.158 , pp. 871-877
    • Spotila, L.D.1    Jacques, P.F.2    Berger, P.B.3
  • 33
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modification of low density lipoprotein that increases its atherogenicity
    • Steinberg D, Parthasarathy TE, Carew TE, et al. Beyond cholesterol: modification of low density lipoprotein that increases its atherogenicity. N Engl J Med 1989; 320:915-924.
    • (1989) N Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, T.E.2    Carew, T.E.3
  • 34
    • 0002198623 scopus 로고    scopus 로고
    • Paraoxonase polymorphism MetLeu54 is associated with modified serum concentrations of the enzyme: A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes
    • Garin MC, James RW, Dussoix P, et al. Paraoxonase polymorphism MetLeu54 is associated with modified serum concentrations of the enzyme: a possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes. J Clin Invest 1997; 99:62-66.
    • (1997) J Clin Invest , vol.99 , pp. 62-66
    • Garin, M.C.1    James, R.W.2    Dussoix, P.3
  • 35
    • 0033973018 scopus 로고    scopus 로고
    • Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations
    • Leviev I, James RW. Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations. Arterioscler Thromb Vasc Biol 2000; 20:516-521.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 516-521
    • Leviev, I.1    James, R.W.2
  • 36
    • 0242661468 scopus 로고    scopus 로고
    • Northwick Park Heart Study II. Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II
    • Robertson KS, Hawe E, Miller GJ, et al. Northwick Park Heart Study II. Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II. Biochim Biophys Acta 2003; 1639:203-212.
    • (2003) Biochim Biophys Acta , vol.1639 , pp. 203-212
    • Robertson, K.S.1    Hawe, E.2    Miller, G.J.3
  • 37
    • 1542331537 scopus 로고    scopus 로고
    • Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: Meta-analysis of 43 studies
    • Wheeler JG, Keavney BD, Watkins H, et al. Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies. Lancet 2004; 363:689-695. The most important metaanalysis of PON polymorphisms.
    • (2004) Lancet , vol.363 , pp. 689-695
    • Wheeler, J.G.1    Keavney, B.D.2    Watkins, H.3
  • 38
    • 4143081781 scopus 로고    scopus 로고
    • Paraoxonase polymorphisms and coronary heart disease
    • Durrington PN, Mackness B, Mackness MI. Paraoxonase polymorphisms and coronary heart disease. Lancet 2004; 364:579-580.
    • (2004) Lancet , vol.364 , pp. 579-580
    • Durrington, P.N.1    Mackness, B.2    Mackness, M.I.3
  • 39
    • 0038579858 scopus 로고    scopus 로고
    • Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status
    • Jarvik GP, Jampsa R, Richter RJ, et al. Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. Pharmacogenetics 2003; 13:291-295.
    • (2003) Pharmacogenetics , vol.13 , pp. 291-295
    • Jarvik, G.P.1    Jampsa, R.2    Richter, R.J.3
  • 40
    • 0038717034 scopus 로고    scopus 로고
    • Independent effects of the -219 G>T and epsilon 2/epsilon 3/epsilon 4 polymorphisms in the apolipoprotein E gene on coronary artery disease: The Southampton Atherosclerosis Study
    • Ye S, Dunleavey L, Bannister W, et al. Independent effects of the -219 G>T and epsilon 2/epsilon 3/epsilon 4 polymorphisms in the apolipoprotein E gene on coronary artery disease: the Southampton Atherosclerosis Study. Eur J Hum Genet 2003; 11:437-443.
    • (2003) Eur J Hum Genet , vol.11 , pp. 437-443
    • Ye, S.1    Dunleavey, L.2    Bannister, W.3
  • 41
    • 0034013067 scopus 로고    scopus 로고
    • Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations: The ECTIM study
    • Lambert JC, Brousseau T, Defosse V, et al. Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations: the ECTIM study. Hum Mol Genet 2000; 9:57-61.
    • (2000) Hum Mol Genet , vol.9 , pp. 57-61
    • Lambert, J.C.1    Brousseau, T.2    Defosse, V.3
  • 42
    • 0032874367 scopus 로고    scopus 로고
    • APOE genotype as a risk factor for ischemic cerebrovascular disease: A meta-analysis
    • McCarron MO, Delong D, Alberts MJ. APOE genotype as a risk factor for ischemic cerebrovascular disease: a meta-analysis. Neurology 1999; 53:1308-1311.
    • (1999) Neurology , vol.53 , pp. 1308-1311
    • McCarron, M.O.1    Delong, D.2    Alberts, M.J.3
  • 43
    • 0842310801 scopus 로고    scopus 로고
    • Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults
    • Pezzini A, Grassi M, Del Zotto E, et al. Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults. Stroke 2004; 35:438-442.
    • (2004) Stroke , vol.35 , pp. 438-442
    • Pezzini, A.1    Grassi, M.2    Del Zotto, E.3
  • 44
    • 11144358458 scopus 로고    scopus 로고
    • The impact of APOE on myocardial infarction, stroke, and dementia: The Rotterdam Study
    • Slooter AJ, Cruts M, Hofman A, et al. The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study. Neurology 2004; 62:1196-1198.
    • (2004) Neurology , vol.62 , pp. 1196-1198
    • Slooter, A.J.1    Cruts, M.2    Hofman, A.3
  • 45
    • 1842850661 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism and carotid atherosclerosis in patients with coronary disease
    • Fernandez-Miranda C, Aranda JL, Martin MA, et al. Apolipoprotein E polymorphism and carotid atherosclerosis in patients with coronary disease. Int J Cardiol 2004; 94:209-212.
    • (2004) Int J Cardiol , vol.94 , pp. 209-212
    • Fernandez-Miranda, C.1    Aranda, J.L.2    Martin, M.A.3
  • 46
    • 16644370972 scopus 로고    scopus 로고
    • Association of APOE genotype with carotid atherosclerosis in men and women: The Framingham Heart Study
    • Elosua R, Ordovas JM, Cupples LA, et al. Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. J Lipid Res 2004; 45:1868-1875. This paper illustrates the importance of sex stratification and the role of diabetes in the APOE-atherosclerosis interaction. The results were confirmed by meta-analysis.
    • (2004) J Lipid Res , vol.45 , pp. 1868-1875
    • Elosua, R.1    Ordovas, J.M.2    Cupples, L.A.3
  • 47
    • 1342301462 scopus 로고    scopus 로고
    • Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure
    • Schut AF, Sayed-Tabatabaei FA, Witteman JC, et al. Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure. J Hypertens 2004; 22:313-319.
    • (2004) J Hypertens , vol.22 , pp. 313-319
    • Schut, A.F.1    Sayed-Tabatabaei, F.A.2    Witteman, J.C.3
  • 48
    • 1542360033 scopus 로고    scopus 로고
    • The G-217A variant of the angiotensinogen gene affects basal transcription and is associated with hypertension in a Taiwanese population
    • Wu SJ, Chiang FT, Jiang JR, et al. The G-217A variant of the angiotensinogen gene affects basal transcription and is associated with hypertension in a Taiwanese population. J Hypertens 2003; 21:2061-2067.
    • (2003) J Hypertens , vol.21 , pp. 2061-2067
    • Wu, S.J.1    Chiang, F.T.2    Jiang, J.R.3
  • 49
    • 3843067473 scopus 로고    scopus 로고
    • Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: Single locus genotype vs. haplotype analysis
    • Wu SJ, Chiang FT, Chen WJ, et al. Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype vs. haplotype analysis. Physiol Genomics 2004; 17:79-86.
    • (2004) Physiol Genomics , vol.17 , pp. 79-86
    • Wu, S.J.1    Chiang, F.T.2    Chen, W.J.3
  • 50
    • 0141962650 scopus 로고    scopus 로고
    • Genetic variants of angiotensin II receptors and cardiovascular risk in hypertension
    • Jones A, Dhamrait SS, Payne JR, et al. Genetic variants of angiotensin II receptors and cardiovascular risk in hypertension. Hypertension 2003; 42:500-506.
    • (2003) Hypertension , vol.42 , pp. 500-506
    • Jones, A.1    Dhamrait, S.S.2    Payne, J.R.3
  • 51
    • 0345832332 scopus 로고    scopus 로고
    • The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore
    • Lai CQ, Tai ES, Tan CE, et al. The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore. J Lipid Res 2003; 44:2365-2373.
    • (2003) J Lipid Res , vol.44 , pp. 2365-2373
    • Lai, C.Q.1    Tai, E.S.2    Tan, C.E.3
  • 52
    • 1242341216 scopus 로고    scopus 로고
    • The influence of APOAV polymorphisms (T-1131>C and S19>W) on plasma triglyceride levels and risk of myocardial infarction
    • Hubacek JA, Skodova Z, Adamkova V, et al. The influence of APOAV polymorphisms (T-1131>C and S19>W) on plasma triglyceride levels and risk of myocardial infarction. Clin Genet 2004; 65:126-130.
    • (2004) Clin Genet , vol.65 , pp. 126-130
    • Hubacek, J.A.1    Skodova, Z.2    Adamkova, V.3
  • 53
    • 20244385557 scopus 로고    scopus 로고
    • Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese
    • Liu H, Zhang S, Lin J, et al. Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese. Metabolism 2005; 54:568-572.
    • (2005) Metabolism , vol.54 , pp. 568-572
    • Liu, H.1    Zhang, S.2    Lin, J.3
  • 54
    • 10744231400 scopus 로고    scopus 로고
    • Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease
    • Szalai C, Keszei M, Duba J, et al. Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease. Atherosclerosis 2004; 173:109-114.
    • (2004) Atherosclerosis , vol.173 , pp. 109-114
    • Szalai, C.1    Keszei, M.2    Duba, J.3
  • 55
    • 12144291123 scopus 로고    scopus 로고
    • Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans
    • Austin MA, Talmud PJ, Farin FM, et al. Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans. Biochim Biophys Acta 2004; 1688:1-9.
    • (2004) Biochim Biophys Acta , vol.1688 , pp. 1-9
    • Austin, M.A.1    Talmud, P.J.2    Farin, F.M.3
  • 56
    • 0141841622 scopus 로고    scopus 로고
    • A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia
    • Kao JT, Wen HC, Chien KL, et al. A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia. Hum Mol Genet 2003; 12:2533-2539.
    • (2003) Hum Mol Genet , vol.12 , pp. 2533-2539
    • Kao, J.T.1    Wen, H.C.2    Chien, K.L.3
  • 57
    • 10744220794 scopus 로고    scopus 로고
    • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
    • Helgadottir A, Manolescu A, Thorleifsson G, et al. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 2004; 36:233-239. A well designed study including linkage analysis, microsatellite association study, LD mapping, haplotype association and screening for SNPs in ALOX5AP, which clearly defines this molecule as a new candidate gene for CAD.
    • (2004) Nat Genet , vol.36 , pp. 233-239
    • Helgadottir, A.1    Manolescu, A.2    Thorleifsson, G.3
  • 58
    • 6344240884 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction
    • Cornelis MC, El-Sohemy A, Campos H. Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction. J Med Genet 2004; 41:758-762.
    • (2004) J Med Genet , vol.41 , pp. 758-762
    • Cornelis, M.C.1    El-Sohemy, A.2    Campos, H.3
  • 59
    • 2542598663 scopus 로고    scopus 로고
    • Endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298→Asp and T-786→C polymorphisms
    • Paradossi U, Ciofini E, Clerico A, et al. Endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298→Asp and T-786→C polymorphisms. Stroke 2004; 35:1305-1309.
    • (2004) Stroke , vol.35 , pp. 1305-1309
    • Paradossi, U.1    Ciofini, E.2    Clerico, A.3
  • 60
    • 3242784995 scopus 로고    scopus 로고
    • Estrogen receptor beta polymorphisms are associated with bone mass in women and men: The Framingham Study
    • Shearman AM, Karasik D, Gruenthal KM, et al. Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study. J Bone Miner Res 2004; 19:773-781.
    • (2004) J Bone Miner Res , vol.19 , pp. 773-781
    • Shearman, A.M.1    Karasik, D.2    Gruenthal, K.M.3
  • 61
    • 2942711549 scopus 로고    scopus 로고
    • Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction
    • Schuit SC, Oei HH, Witteman JC, et al. Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA 2004; 291:2969-2977.
    • (2004) JAMA , vol.291 , pp. 2969-2977
    • Schuit, S.C.1    Oei, H.H.2    Witteman, J.C.3
  • 62
    • 18744407845 scopus 로고    scopus 로고
    • Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
    • Ozaki K, Ohnishi Y, Iida A, et al. Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet 2002; 32:650-654.
    • (2002) Nat Genet , vol.32 , pp. 650-654
    • Ozaki, K.1    Ohnishi, Y.2    Iida, A.3
  • 63
    • 11044220307 scopus 로고    scopus 로고
    • Transcription factor MEF2A mutations in patients with coronary artery disease
    • Bhagavatula MR, Fan C, Shen GQ, et al. Transcription factor MEF2A mutations in patients with coronary artery disease. Hum Mol Genet 2004; 13:3181-3188. Two percent of the CAD/MI population may carry mutations in the MEF2A gene.
    • (2004) Hum Mol Genet , vol.13 , pp. 3181-3188
    • Bhagavatula, M.R.1    Fan, C.2    Shen, G.Q.3
  • 64
    • 33644845453 scopus 로고    scopus 로고
    • The Pro279Leu variant in the transcription factor MEF2A is associated with myocardial infarction
    • 15 June [E-pub ahead of print]
    • Gonzalez P, Garcia-Castro M, Reguero JR, et al. The Pro279Leu variant in the transcription factor MEF2A is associated with myocardial infarction. J Med Genet 2005; 15 June [E-pub ahead of print].
    • (2005) J Med Genet
    • Gonzalez, P.1    Garcia-Castro, M.2    Reguero, J.R.3
  • 65
    • 10744230695 scopus 로고    scopus 로고
    • Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese
    • Nojiri T, Morita H, Imai Y, et al. Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese. Int J Cardiol 2003; 92:181-186.
    • (2003) Int J Cardiol , vol.92 , pp. 181-186
    • Nojiri, T.1    Morita, H.2    Imai, Y.3
  • 66
    • 18244397178 scopus 로고    scopus 로고
    • Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis
    • Bevan S, Porteous L, Sitzer M, Markus HS. Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis. Stroke 2005; 36:949-953.
    • (2005) Stroke , vol.36 , pp. 949-953
    • Bevan, S.1    Porteous, L.2    Sitzer, M.3    Markus, H.S.4
  • 67
    • 1542316808 scopus 로고    scopus 로고
    • PON1 M/L55 mutation protects high-risk patients against coronary artery disease
    • Oliveira SA, Mansur AP, Ribeiro CC, et al. PON1 M/L55 mutation protects high-risk patients against coronary artery disease. Int J Cardiol 2004; 94:73-77.
    • (2004) Int J Cardiol , vol.94 , pp. 73-77
    • Oliveira, S.A.1    Mansur, A.P.2    Ribeiro, C.C.3
  • 68
    • 0142209179 scopus 로고    scopus 로고
    • Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: A meta-analysis
    • Masud S, Ye S, SAS Group. Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis. J Med Genet 2003; 40:773-780.
    • (2003) J Med Genet , vol.40 , pp. 773-780
    • Masud, S.1    Ye, S.2
  • 69
    • 1642580752 scopus 로고    scopus 로고
    • Association of the Lewis genotype with cardiovascular risk factors and subclinical carotid atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study
    • Cakir B, Heiss G, Pankow JS, et al. Association of the Lewis genotype with cardiovascular risk factors and subclinical carotid atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) study. J Intern Med 2004; 255:40-51.
    • (2004) J Intern Med , vol.255 , pp. 40-51
    • Cakir, B.1    Heiss, G.2    Pankow, J.S.3
  • 70
    • 4644287673 scopus 로고    scopus 로고
    • Adducin, renal intermediate phenotypes, and hypertension
    • Bianchi G, Manunta P. Adducin, renal intermediate phenotypes, and hypertension. Hypertension 2004; 44:394-395.
    • (2004) Hypertension , vol.44 , pp. 394-395
    • Bianchi, G.1    Manunta, P.2
  • 71
    • 0037477383 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: A meta-analysis
    • Sayed-Tabatabaei FA, Houwing-Duistermaat JJ, van Duijn CM, et al. Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis. Stroke 2003; 34:1634-1639.
    • (2003) Stroke , vol.34 , pp. 1634-1639
    • Sayed-Tabatabaei, F.A.1    Houwing-Duistermaat, J.J.2    Van Duijn, C.M.3
  • 72
    • 2142645180 scopus 로고    scopus 로고
    • The quest for cardiovascular health in the genomic era: Nutrigenetics and plasma lipoproteins
    • Ordovas JM. The quest for cardiovascular health in the genomic era: nutrigenetics and plasma lipoproteins. Proc Nutr Soc 2004; 63:145-152.
    • (2004) Proc Nutr Soc , vol.63 , pp. 145-152
    • Ordovas, J.M.1
  • 73
    • 0142010558 scopus 로고    scopus 로고
    • Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease
    • Boekholdt SM, Thompson JF. Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease. J Lipid Res 2003; 44:1080-1093.
    • (2003) J Lipid Res , vol.44 , pp. 1080-1093
    • Boekholdt, S.M.1    Thompson, J.F.2
  • 74
    • 1642368920 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase genotype and ischemic heart disease: Meta-analysis of 26 studies involving 23028 subjects
    • Casas JP, Bautista LE, Humphries SE, Hingorani AD. Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects. Circulation 2004; 109:1359-1365.
    • (2004) Circulation , vol.109 , pp. 1359-1365
    • Casas, J.P.1    Bautista, L.E.2    Humphries, S.E.3    Hingorani, A.D.4
  • 75
    • 20444445722 scopus 로고    scopus 로고
    • Homocysteine, MTHFR and risk of venous thrombosis: A meta-analysis of published epidemiological studies
    • Den Heijer M, Lewington S, Clarke R. Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies. J Thromb Haemost 2005; 3:292-299.
    • (2005) J Thromb Haemost , vol.3 , pp. 292-299
    • Den Heijer, M.1    Lewington, S.2    Clarke, R.3
  • 76
    • 23644439454 scopus 로고    scopus 로고
    • The association of the PON1 Q192R polymorphism with coronary heart disease: Findings from the British Women's Heart and Health cohort study and a meta-analysis
    • Lawlor DA, Day IN, Gaunt TR, et al. The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis. BMC Genet 2004; 5:17.
    • (2004) BMC Genet , vol.5 , pp. 17
    • Lawlor, D.A.1    Day, I.N.2    Gaunt, T.R.3
  • 77
    • 0242362217 scopus 로고    scopus 로고
    • The factor V HR2 haplotype and the risk of venous thrombosis: A meta-analysis
    • Castaman G, Faioni EM, Tosetto A, Bernardi F. The factor V HR2 haplotype and the risk of venous thrombosis: a meta-analysis. Haematologica 2003; 88:1182-1189.
    • (2003) Haematologica , vol.88 , pp. 1182-1189
    • Castaman, G.1    Faioni, E.M.2    Tosetto, A.3    Bernardi, F.4
  • 78
    • 0344827206 scopus 로고    scopus 로고
    • Mutation of MEF2A in an inherited disorder with features of coronary artery disease
    • Wang L, Fan C, Topol SE, et al. Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science 2003; 302:1578-1581.
    • (2003) Science , vol.302 , pp. 1578-1581
    • Wang, L.1    Fan, C.2    Topol, S.E.3
  • 79
    • 6344289071 scopus 로고    scopus 로고
    • Microarray applications: Emerging technologies and perspectives
    • Mathias G. Microarray applications: emerging technologies and perspectives. Drug Discov Today 2004; 9:915-917.
    • (2004) Drug Discov Today , vol.9 , pp. 915-917
    • Mathias, G.1
  • 80
    • 0037417973 scopus 로고    scopus 로고
    • Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis
    • U S A
    • Spanbroek R, Grabner R, Lotzer K, et al. Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci U S A 2003; 100:1238-1243.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 1238-1243
    • Spanbroek, R.1    Grabner, R.2    Lotzer, K.3
  • 81
    • 13844289142 scopus 로고    scopus 로고
    • Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population
    • Helgadottir A, Gretarsdottir S, St Clair D, et al. Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. Am J Hum Genet 2005; 76:505-509.
    • (2005) Am J Hum Genet , vol.76 , pp. 505-509
    • Helgadottir, A.1    Gretarsdottir, S.2    St. Clair, D.3
  • 82
    • 16844368834 scopus 로고    scopus 로고
    • ALOX5AP gene and the PDE4D gene in a central European population of stroke patients
    • Lohmussaar E, Gschwendtner A, Mueller JC, et al. ALOX5AP gene and the PDE4D gene in a central European population of stroke patients. Stroke 2005; 36:731-736.
    • (2005) Stroke , vol.36 , pp. 731-736
    • Lohmussaar, E.1    Gschwendtner, A.2    Mueller, J.C.3
  • 83
    • 18244403498 scopus 로고    scopus 로고
    • Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: A randomized trial
    • Hakonarson H, Thorvaldsson S, Helgadottir A, et al. Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial. JAMA 2005; 293:2245-2256.
    • (2005) JAMA , vol.293 , pp. 2245-2256
    • Hakonarson, H.1    Thorvaldsson, S.2    Helgadottir, A.3
  • 84
    • 3843138430 scopus 로고    scopus 로고
    • Lack of association of polymorphisms of the lymphotoxin alpha gene with myocardial infarction in Japanese
    • Yamada A, Ichihara S, Murase Y. Lack of association of polymorphisms of the lymphotoxin alpha gene with myocardial infarction in Japanese. J Mol Med 2004; 82:477-483.
    • (2004) J Mol Med , vol.82 , pp. 477-483
    • Yamada, A.1    Ichihara, S.2    Murase, Y.3
  • 85
    • 0142027222 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, lymphotoxin-alpha, and interleukin-10 gene polymorphisms and restenosis after coronary artery stenting
    • Koch W, Tiroch K, von Beckerath N, et al. Tumor necrosis factor-alpha, lymphotoxin-alpha, and interleukin-10 gene polymorphisms and restenosis after coronary artery stenting. Cytokine 2003; 24:161-171.
    • (2003) Cytokine , vol.24 , pp. 161-171
    • Koch, W.1    Tiroch, K.2    Von Beckerath, N.3
  • 86
    • 4644324638 scopus 로고    scopus 로고
    • A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease
    • PROCARDIS Consortium. A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease. Eur J Hum Genet 2004; 12:770-774.
    • (2004) Eur J Hum Genet , vol.12 , pp. 770-774
  • 87
    • 26944479729 scopus 로고    scopus 로고
    • Association of the lymphotoxin-alpha gene Thr26Asn polymorphism with severity of coronary atherosclerosis
    • Laxton R, Pearce E, Kyriakou T, Ye S. Association of the lymphotoxin-alpha gene Thr26Asn polymorphism with severity of coronary atherosclerosis. Genes Immun 2005; 6:539-541.
    • (2005) Genes Immun , vol.6 , pp. 539-541
    • Laxton, R.1    Pearce, E.2    Kyriakou, T.3    Ye, S.4
  • 88
    • 7944229479 scopus 로고    scopus 로고
    • An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene
    • Nakayama T, Soma M, Sato N, et al. An association study in essential hypertension using functional polymorphisms in lymphotoxin-alpha gene. Am J Hypertens 2004; 17:1045-1049.
    • (2004) Am J Hypertens , vol.17 , pp. 1045-1049
    • Nakayama, T.1    Soma, M.2    Sato, N.3
  • 89
    • 2342480580 scopus 로고    scopus 로고
    • Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro
    • Ozaki K, Inoue K, Sato H, et al. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro. Nature 2004; 429:72-75. LGALS2 is significantly associated with susceptibility to MI. These findings suggest a link between the LTA cascade and the pathogenesis of MI.
    • (2004) Nature , vol.429 , pp. 72-75
    • Ozaki, K.1    Inoue, K.2    Sato, H.3
  • 90
    • 0039136346 scopus 로고    scopus 로고
    • A novel human apolipoprotein (apoM)
    • Xu N, Dahlback B. A novel human apolipoprotein (apoM). J Biol Chem 1999; 274:31286-31290.
    • (1999) J Biol Chem , vol.274 , pp. 31286-31290
    • Xu, N.1    Dahlback, B.2
  • 91
    • 0036293085 scopus 로고    scopus 로고
    • Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1 alpha on the expression of apolipoprotein M in HepG2 cells
    • Xu N, Zhang XY, Dong X, et al. Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1 alpha on the expression of apolipoprotein M in HepG2 cells. Biochem Biophys Res Commun 2002; 292:944-950.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 944-950
    • Xu, N.1    Zhang, X.Y.2    Dong, X.3
  • 92
    • 0344412888 scopus 로고    scopus 로고
    • Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1 alpha: Haploinsufficiency is associated with reduced serum apolipoprotein M levels
    • Richter S, Shih DQ, Pearson ER, et al. Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1 alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels. Diabetes 2003; 52:2989-2995.
    • (2003) Diabetes , vol.52 , pp. 2989-2995
    • Richter, S.1    Shih, D.Q.2    Pearson, E.R.3
  • 93
    • 3042613704 scopus 로고    scopus 로고
    • Transforming growth factor-beta downregulates apolipoprotein M in HepG2 cells
    • Xu N, Hurtig M, Zhang XY, et al. Transforming growth factor-beta downregulates apolipoprotein M in HepG2 cells. Biochim Biophys Acta 2004; 1683:33-37.
    • (2004) Biochim Biophys Acta , vol.1683 , pp. 33-37
    • Xu, N.1    Hurtig, M.2    Zhang, X.Y.3
  • 94
    • 3843114406 scopus 로고    scopus 로고
    • Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo
    • Xu N, Nilsson-Ehle P, Hurtig M, Ahren B. Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo. Biochem Biophys Res Commun 2004; 321:916-921. Leptin is physiologically regulating apoM synthesis in vivo.
    • (2004) Biochem Biophys Res Commun , vol.321 , pp. 916-921
    • Xu, N.1    Nilsson-Ehle, P.2    Hurtig, M.3    Ahren, B.4
  • 95
    • 17644393111 scopus 로고    scopus 로고
    • Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis
    • Wolfrum C, Poy MN, Stoffel M. Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis. Nat Med 2005; 11:418-422. ApoM could inhibit formation of atherosclerotic lesions in vivo.
    • (2005) Nat Med , vol.11 , pp. 418-422
    • Wolfrum, C.1    Poy, M.N.2    Stoffel, M.3
  • 96
    • 2542422805 scopus 로고    scopus 로고
    • Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population
    • Kabbara A, Payet N, Cottel D, et al. Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population. Neurosci Lett 2004; 363:139-143.
    • (2004) Neurosci Lett , vol.363 , pp. 139-143
    • Kabbara, A.1    Payet, N.2    Cottel, D.3
  • 97
    • 18244401151 scopus 로고    scopus 로고
    • Localization of a susceptibility gene for common forms of stroke to 5q12
    • Gretarsdottir S, Sveinbjornsdottir S, Jonsson HH, et al. Localization of a susceptibility gene for common forms of stroke to 5q12. Am J Hum Genet 2002; 70:593-603.
    • (2002) Am J Hum Genet , vol.70 , pp. 593-603
    • Gretarsdottir, S.1    Sveinbjornsdottir, S.2    Jonsson, H.H.3
  • 98
    • 0141819194 scopus 로고    scopus 로고
    • The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
    • Gretarsdottir S, Thorleifsson G, Reynisdottir ST, et al. The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet 2003; 353:131-138.
    • (2003) Nat Genet , vol.353 , pp. 131-138
    • Gretarsdottir, S.1    Thorleifsson, G.2    Reynisdottir, S.T.3
  • 99
    • 27144436415 scopus 로고    scopus 로고
    • Dimethylarginine dimethlyaminohydrolase and endothelial dysfunction in the failing heart
    • Chen Y, Li Y, Zhang P, et al. Dimethylarginine dimethlyaminohydrolase and endothelial dysfunction in the failing heart. Am J Physiol Heart Circ Physiol 2005; 289:H2212-H2219.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Chen, Y.1    Li, Y.2    Zhang, P.3
  • 100
    • 0141645386 scopus 로고    scopus 로고
    • Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells
    • Jones LC, Tran CT, Leiper JM, et al. Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. Biochem Biophys Res Commun 2003; 310:836-843.
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 836-843
    • Jones, L.C.1    Tran, C.T.2    Leiper, J.M.3
  • 101
    • 10744220261 scopus 로고    scopus 로고
    • Regulation of the major isoform of human endothelin-converting enzyme-1 by a strong housekeeping promoter modulated by polymorphic microsatellites
    • Funke-Kaiser H, Thomas A, Bremer J, et al. Regulation of the major isoform of human endothelin-converting enzyme-1 by a strong housekeeping promoter modulated by polymorphic microsatellites. J Hypertens 2003; 21:2111-2124.
    • (2003) J Hypertens , vol.21 , pp. 2111-2124
    • Funke-Kaiser, H.1    Thomas, A.2    Bremer, J.3
  • 102
    • 0037440673 scopus 로고    scopus 로고
    • Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation
    • Funke-Kaiser H, Reichenberger F, Kopke K, et al. Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation. Hum Mol Genet 2003; 12:423-433.
    • (2003) Hum Mol Genet , vol.12 , pp. 423-433
    • Funke-Kaiser, H.1    Reichenberger, F.2    Kopke, K.3
  • 103
    • 2142650178 scopus 로고    scopus 로고
    • Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: The EVA study
    • Funalot B, Courbon D, Brousseau T, et al. Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: the EVA study. J Hypertens 2004; 22:739-743.
    • (2004) J Hypertens , vol.22 , pp. 739-743
    • Funalot, B.1    Courbon, D.2    Brousseau, T.3
  • 104
    • 0029585975 scopus 로고
    • Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)
    • Valdenaire O, Rohrbacher E, Mattei MG. Organization of the gene encoding the human endothelin-converting enzyme (ECE-1). J Biol Chem 1995; 270:29794-29798.
    • (1995) J Biol Chem , vol.270 , pp. 29794-29798
    • Valdenaire, O.1    Rohrbacher, E.2    Mattei, M.G.3
  • 105
    • 16544386240 scopus 로고    scopus 로고
    • Expression profiling of cardiovascular disease
    • Archacki S, Wang Q. Expression profiling of cardiovascular disease. Hum Genomics 2004; 1:355-370.
    • (2004) Hum Genomics , vol.1 , pp. 355-370
    • Archacki, S.1    Wang, Q.2
  • 106
    • 0032890205 scopus 로고    scopus 로고
    • Mortality in treated heterozygous familial hypercholesterolemia: Implications for clinical management
    • Scientific Steering Committee on behalf of the Simon Broome Register Group. Mortality in treated heterozygous familial hypercholesterolemia: implications for clinical management. Atherosclerosis 1999; 142:105-112.
    • (1999) Atherosclerosis , vol.142 , pp. 105-112
  • 107
    • 0344081920 scopus 로고    scopus 로고
    • Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors
    • Pauciullo P, Giannino A, De Michele M, et al. Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors. Metabolism 2003; 52:1433-1438.
    • (2003) Metabolism , vol.52 , pp. 1433-1438
    • Pauciullo, P.1    Giannino, A.2    De Michele, M.3
  • 108
    • 10744228935 scopus 로고    scopus 로고
    • The androgen receptor gene CAG polymorphism is associated with the severity of coronary artery disease in men
    • Alevizaki M, Cimponeriu AT, Garofallaki M, et al. The androgen receptor gene CAG polymorphism is associated with the severity of coronary artery disease in men. Clin Endocrinol 2003; 59:749-755.
    • (2003) Clin Endocrinol , vol.59 , pp. 749-755
    • Alevizaki, M.1    Cimponeriu, A.T.2    Garofallaki, M.3
  • 109
    • 10244248483 scopus 로고    scopus 로고
    • Polymorphism R92Q of the tumour necrosis factor receptor 1 gene is associated with myocardial infarction and carotid intima-media thickness: The ECTIM, AXA, EVA and GENIC studies
    • Poirier O, Nicaud V, Gariepy J, et al. Polymorphism R92Q of the tumour necrosis factor receptor 1 gene is associated with myocardial infarction and carotid intima-media thickness: the ECTIM, AXA, EVA and GENIC studies. Eur J Hum Genet 2004; 12:213-219.
    • (2004) Eur J Hum Genet , vol.12 , pp. 213-219
    • Poirier, O.1    Nicaud, V.2    Gariepy, J.3
  • 110
    • 3242771549 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima-media thickness of the carotid artery in hypertensive patients
    • The Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA)
    • Brandstrom H, Stiger F, Kahan T, et al. A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima-media thickness of the carotid artery in hypertensive patients. The Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) Blood Press 2004; 13:152-157.
    • (2004) Blood Press , vol.13 , pp. 152-157
    • Brandstrom, H.1    Stiger, F.2    Kahan, T.3
  • 111
    • 0346502718 scopus 로고    scopus 로고
    • Identification of new genes differentially expressed in coronary artery disease by expression profiling
    • Archacki SR, Angheloiu G, Tian XL, et al. Identification of new genes differentially expressed in coronary artery disease by expression profiling. Physiol Genomics 2003; 15:65-74.
    • (2003) Physiol Genomics , vol.15 , pp. 65-74
    • Archacki, S.R.1    Angheloiu, G.2    Tian, X.L.3
  • 112
    • 4744362880 scopus 로고    scopus 로고
    • Genetic and environmental contributions to carotid intima-media thickness and obesity phenotypes in the Northern Manhattan Family Study
    • Juo SH, Lin HF, Rundek T, et al. Genetic and environmental contributions to carotid intima-media thickness and obesity phenotypes in the Northern Manhattan Family Study. Stroke 2004; 35:2243-2247.
    • (2004) Stroke , vol.35 , pp. 2243-2247
    • Juo, S.H.1    Lin, H.F.2    Rundek, T.3
  • 113
    • 2342591299 scopus 로고    scopus 로고
    • Large scale association analysis for identification of genes underlying premature coronary heart disease: Cumulative perspective from analysis of 111 candidate genes
    • McCarthy JJ, Parker A, Salem R, et al. Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes. J Med Genet 2004; 41:334-341.
    • (2004) J Med Genet , vol.41 , pp. 334-341
    • McCarthy, J.J.1    Parker, A.2    Salem, R.3
  • 114
    • 0142107360 scopus 로고    scopus 로고
    • Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors
    • Hirashiki A, Yamada Y, Murase Y, et al. Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors. J Am Coll Cardiol 2003; 42:1429-1437.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1429-1437
    • Hirashiki, A.1    Yamada, Y.2    Murase, Y.3
  • 115
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • Delerive P, Fruchart C, Staels B. Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 2001; 169:453-459.
    • (2001) J Endocrinol , vol.169 , pp. 453-459
    • Delerive, P.1    Fruchart, C.2    Staels, B.3
  • 116
    • 10744223422 scopus 로고    scopus 로고
    • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia
    • Tao L, Liu HR, Gao E, et al. Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. Circulation 2003; 108:2805-2811.
    • (2003) Circulation , vol.108 , pp. 2805-2811
    • Tao, L.1    Liu, H.R.2    Gao, E.3
  • 117
    • 13944283346 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and cardiovascular remodeling
    • Schiffrin EL. Peroxisome proliferator-activated receptors and cardiovascular remodeling. Am J Physiol Heart Circ Physiol 2004; 288:H1037-H1043.
    • (2004) Am J Physiol Heart Circ Physiol , vol.288
    • Schiffrin, E.L.1
  • 118
    • 0345097385 scopus 로고    scopus 로고
    • Gene-gene interaction of PPARgamma and ApoE affects coronary heart disease risk
    • Peng DQ, Zhao SP, Nie S, Li J. Gene-gene interaction of PPARgamma and ApoE affects coronary heart disease risk. Int J Cardiol 2003; 92:257-263.
    • (2003) Int J Cardiol , vol.92 , pp. 257-263
    • Peng, D.Q.1    Zhao, S.P.2    Nie, S.3    Li, J.4
  • 119
    • 1342343901 scopus 로고    scopus 로고
    • The Leu554Phe polymorphism in the E-selectin gene is associated with blood pressure in overweight people
    • Marteau JB, Sass C, Pfister M, et al. The Leu554Phe polymorphism in the E-selectin gene is associated with blood pressure in overweight people. J Hypertens 2004; 22:305-311.
    • (2004) J Hypertens , vol.22 , pp. 305-311
    • Marteau, J.B.1    Sass, C.2    Pfister, M.3
  • 120
    • 1642268936 scopus 로고    scopus 로고
    • Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges
    • Martin S, Nicaud V, Humphries SE, et al. Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges. Biochim Biophys Acta 2003; 1637:217-225.
    • (2003) Biochim Biophys Acta , vol.1637 , pp. 217-225
    • Martin, S.1    Nicaud, V.2    Humphries, S.E.3
  • 121
    • 1842864853 scopus 로고    scopus 로고
    • Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels
    • Pennacchio LA, Olivier M, Hubacek JA, et al. Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Molec Genet 2002; 11:3031-3038.
    • (2002) Hum Molec Genet , vol.11 , pp. 3031-3038
    • Pennacchio, L.A.1    Olivier, M.2    Hubacek, J.A.3
  • 122
    • 0242288462 scopus 로고    scopus 로고
    • The single nucleotide polymorphism -1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia
    • Evans D, Buchwald A, Beil FU. The single nucleotide polymorphism -1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia. J Mol Med 2003; 81:645-654.
    • (2003) J Mol Med , vol.81 , pp. 645-654
    • Evans, D.1    Buchwald, A.2    Beil, F.U.3
  • 123
    • 0242367272 scopus 로고    scopus 로고
    • Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: The Bogalusa Heart Study
    • Xin X, Srinivasan SR, Chen W, et al. Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study. Metabolism 2003; 52:1337-1342.
    • (2003) Metabolism , vol.52 , pp. 1337-1342
    • Xin, X.1    Srinivasan, S.R.2    Chen, W.3
  • 124
    • 23444456177 scopus 로고    scopus 로고
    • Hypertriglyceridemia: Interaction between APOE and APOAV variants
    • Hubacek JA, Horinek A, Skodova Z, et al. Hypertriglyceridemia: interaction between APOE and APOAV variants. Clin Chem 2005; 51:1311-1313.
    • (2005) Clin Chem , vol.51 , pp. 1311-1313
    • Hubacek, J.A.1    Horinek, A.2    Skodova, Z.3
  • 125
    • 2542456397 scopus 로고    scopus 로고
    • The lipoprotein lipase S447X polymorphism and plasma lipids: Interactions with APOE polymorphisms, smoking, and alcohol consumption
    • Lee J, Tan CS, Chia KS, et al. The lipoprotein lipase S447X polymorphism and plasma lipids: interactions with APOE polymorphisms, smoking, and alcohol consumption. J Lipid Res 2004; 45:1132-1139.
    • (2004) J Lipid Res , vol.45 , pp. 1132-1139
    • Lee, J.1    Tan, C.S.2    Chia, K.S.3
  • 126
    • 0348134971 scopus 로고    scopus 로고
    • West of Scotland Coronary Prevention Study. Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men
    • Skogsberg J, McMahon AD, Karpe F, et al. West of Scotland Coronary Prevention Study. Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men. J Intern Med 2003; 254:597-604.
    • (2003) J Intern Med , vol.254 , pp. 597-604
    • Skogsberg, J.1    McMahon, A.D.2    Karpe, F.3
  • 127
    • 22244458270 scopus 로고    scopus 로고
    • Angiotensin converting enzyme gene, smoking and mortality in a population-based study
    • Arias-Vasquez A, Sayed-Tabatabaei FA, Schut AF, et al. Angiotensin converting enzyme gene, smoking and mortality in a population-based study. Eur J Clin Invest 2005; 35:444-449.
    • (2005) Eur J Clin Invest , vol.35 , pp. 444-449
    • Arias-Vasquez, A.1    Sayed-Tabatabaei, F.A.2    Schut, A.F.3
  • 128
    • 0142157175 scopus 로고    scopus 로고
    • Effects of the hepatic lipase gene and physical activity on coronary heart disease risk
    • Hokanson JE, Kamboh MI, Scarboro S, et al. Effects of the hepatic lipase gene and physical activity on coronary heart disease risk. Am J Epidemiol 2003; 158:836-843.
    • (2003) Am J Epidemiol , vol.158 , pp. 836-843
    • Hokanson, J.E.1    Kamboh, M.I.2    Scarboro, S.3
  • 129
    • 0347990586 scopus 로고    scopus 로고
    • Lipoprotein lipase is a gene for insulin resistance in Mexican Americans
    • Goodarzi MO, Guo X, Taylor KD, et al. Lipoprotein lipase is a gene for insulin resistance in Mexican Americans. Diabetes 2004; 53:214-220.
    • (2004) Diabetes , vol.53 , pp. 214-220
    • Goodarzi, M.O.1    Guo, X.2    Taylor, K.D.3
  • 130
    • 7644225300 scopus 로고    scopus 로고
    • Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers
    • Jerrard-Dunne P, Sitzer M, Risley P, et al. Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers. Stroke 2004; 35:2438-2443.
    • (2004) Stroke , vol.35 , pp. 2438-2443
    • Jerrard-Dunne, P.1    Sitzer, M.2    Risley, P.3


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