메뉴 건너뛰기




Volumn 496, Issue 1, 2006, Pages 1-12

Drosophila synaptotagmin I null mutants show severe alterations in vesicle populations but calcium-binding motif mutants do not

Author keywords

Neuromuscular junction; Synapse; Synaptic; Ultrastructure

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; MUTANT PROTEIN; NEUROTRANSMITTER; SYNAPTOTAGMIN; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

EID: 33645459427     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.20868     Document Type: Article
Times cited : (11)

References (75)
  • 1
    • 0027325492 scopus 로고
    • Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophlia larvae
    • Atwood HL, Govind CK, Wu CF. 1993. Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophlia larvae. J Neurobiol 24:1008-1024.
    • (1993) J Neurobiol , vol.24 , pp. 1008-1024
    • Atwood, H.L.1    Govind, C.K.2    Wu, C.F.3
  • 2
    • 0022270911 scopus 로고
    • Calcium entry and transmitter release at voltage-clamped nerve terminals of squid
    • Augustine GJ, Charlton MP, Smith SJ. 1985. Calcium entry and transmitter release at voltage-clamped nerve terminals of squid. J Physiol 367:163-181.
    • (1985) J Physiol , vol.367 , pp. 163-181
    • Augustine, G.J.1    Charlton, M.P.2    Smith, S.J.3
  • 3
    • 1842475284 scopus 로고    scopus 로고
    • Fusion pore dynamics are regulated by synaptotagmin · t-SNARE interactions
    • Bai J, Wang CT, Richards DA, Jackson MB, Chapman ER. 2004. Fusion pore dynamics are regulated by synaptotagmin · t-SNARE interactions. Neuron 41:929-942.
    • (2004) Neuron , vol.41 , pp. 929-942
    • Bai, J.1    Wang, C.T.2    Richards, D.A.3    Jackson, M.B.4    Chapman, E.R.5
  • 4
    • 20444370233 scopus 로고    scopus 로고
    • Synaptotagmin mutants Y311N and K326/327A alter the calcium dependence of neurotransmission
    • Borden CR, Stevens CF, Sullivan JM, Zhu Y. 2005. Synaptotagmin mutants Y311N and K326/327A alter the calcium dependence of neurotransmission. Mol Cell Neurosci 29:462-470.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 462-470
    • Borden, C.R.1    Stevens, C.F.2    Sullivan, J.M.3    Zhu, Y.4
  • 7
    • 0026631563 scopus 로고
    • Synaptotagmin: A calcium sensor on the synaptic vesicle surface
    • Brose N, Petrenko AG, Südhof TC, Jahn R. 1992. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science 256:1021-1025.
    • (1992) Science , vol.256 , pp. 1021-1025
    • Brose, N.1    Petrenko, A.G.2    Südhof, T.C.3    Jahn, R.4
  • 8
    • 0028970788 scopus 로고
    • 2+ regulates the interaction between synaptotagmin and syntaxin 1
    • 2+ regulates the interaction between synaptotagmin and syntaxin 1. J Biol Chem 270:23667-23671.
    • (1995) J Biol Chem , vol.270 , pp. 23667-23671
    • Chapman, E.R.1    Hanson, P.I.2    An, S.3    Jahn, R.4
  • 10
    • 0036017804 scopus 로고    scopus 로고
    • 2+-dependent reversible docking of granules to the plasma membrane
    • 2+-dependent reversible docking of granules to the plasma membrane. Traffic 3:496-511.
    • (2002) Traffic , vol.3 , pp. 496-511
    • Chieregatti, E.1    Witkin, J.W.2    Baldini, G.3
  • 14
    • 0028351171 scopus 로고
    • The effect on synaptic physiology of synaptotagmin mutations in Drosophila
    • DiAntonio A, Schwarz TL. 1994. The effect on synaptic physiology of synaptotagmin mutations in Drosophila. Neuron 12:909-920.
    • (1994) Neuron , vol.12 , pp. 909-920
    • DiAntonio, A.1    Schwarz, T.L.2
  • 15
    • 0035904238 scopus 로고    scopus 로고
    • 2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis
    • 2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis. J Cell Biol 154:1117-1123.
    • (2001) J Cell Biol , vol.154 , pp. 1117-1123
    • Earles, C.A.1    Bai, J.2    Wang, P.3    Chapman, E.R.4
  • 16
    • 0033565996 scopus 로고    scopus 로고
    • The stoned proteins regulate synaptic vesicle recycling in the presynaptic terminal
    • Fergestad T, Davis WS, Broadie K. 1999. The stoned proteins regulate synaptic vesicle recycling in the presynaptic terminal. J Neurosci 19:5847-5860.
    • (1999) J Neurosci , vol.19 , pp. 5847-5860
    • Fergestad, T.1    Davis, W.S.2    Broadie, K.3
  • 19
    • 0034613079 scopus 로고    scopus 로고
    • Drosophila AD3 mutation of synaptotagmin impairs calcium-dependent self-oligomerization activity
    • Fukuda M, Kabayama H, Mikoshiba K. 2000a. Drosophila AD3 mutation of synaptotagmin impairs calcium-dependent self-oligomerization activity. FEBS Lett 482:269-272.
    • (2000) FEBS Lett , vol.482 , pp. 269-272
    • Fukuda, M.1    Kabayama, H.2    Mikoshiba, K.3
  • 21
    • 0025879767 scopus 로고
    • Synaptotagmin II. A novel differentially distributed form of synaptotagmin
    • Geppert M, Archer BT 3rd, Sudhof TC. 1991. Synaptotagmin II. A novel differentially distributed form of synaptotagmin. J Biol Chem 266:13548-13552.
    • (1991) J Biol Chem , vol.266 , pp. 13548-13552
    • Geppert, M.1    Archer III, B.T.2    Sudhof, T.C.3
  • 24
    • 0018849155 scopus 로고
    • Presynaptic dense bars at neuromuscular synapses of the lobster, homarus americanus
    • Govind CK, De Rosa RA, Pearce J. 1980. Presynaptic dense bars at neuromuscular synapses of the lobster, homarus americanus. Cell Tissue Res 207:81-88.
    • (1980) Cell Tissue Res , vol.207 , pp. 81-88
    • Govind, C.K.1    De Rosa, R.A.2    Pearce, J.3
  • 25
    • 0018746093 scopus 로고
    • Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release
    • Heuser JE, Reese TS, Dennis MJ, Jan Y, Jan L, Evans L. 1979. Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release. J Cell Biol 81:275-300.
    • (1979) J Cell Biol , vol.81 , pp. 275-300
    • Heuser, J.E.1    Reese, T.S.2    Dennis, M.J.3    Jan, Y.4    Jan, L.5    Evans, L.6
  • 26
    • 0035921422 scopus 로고    scopus 로고
    • The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis
    • Jarousse N, Kelly RB. 2001. The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis. J Cell Biol 154:857-866.
    • (2001) J Cell Biol , vol.154 , pp. 857-866
    • Jarousse, N.1    Kelly, R.B.2
  • 27
    • 0037744845 scopus 로고    scopus 로고
    • Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif
    • Jarousse N, Wilson JD, Arac D, Rizo J, Kelly RB. 2003. Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif. Traffic 4:468-478.
    • (2003) Traffic , vol.4 , pp. 468-478
    • Jarousse, N.1    Wilson, J.D.2    Arac, D.3    Rizo, J.4    Kelly, R.B.5
  • 28
    • 0027301138 scopus 로고
    • Ultrastructure of neuromuscular junctions in Drosophila: Comparison of wild type and mutants with increased excitability
    • Jia XX, Gorczyca M, Budnik V. 1993a. Ultrastructure of neuromuscular junctions in Drosophila: comparison of wild type and mutants with increased excitability. J Neurobiol 24:1025-1044.
    • (1993) J Neurobiol , vol.24 , pp. 1025-1044
    • Jia, X.X.1    Gorczyca, M.2    Budnik, V.3
  • 29
    • 0027301138 scopus 로고
    • Ultrastructure of neuromuscular junctions in Drosophila: Comparison of wild type and mutants with increased excitability [erratum appears in J Neurobiol 1994 25:893-895]
    • Jia XX, Gorczyca M, Budnik V. 1993b. Ultrastructure of neuromuscular junctions in Drosophila: comparison of wild type and mutants with increased excitability [erratum appears in J Neurobiol 1994 25:893-895]. J Neurobiol 24:1025-1044.
    • (1993) J Neurobiol , vol.24 , pp. 1025-1044
    • Jia, X.X.1    Gorczyca, M.2    Budnik, V.3
  • 30
    • 0024511443 scopus 로고
    • Stereotypic morphology of glutamatergic synapses on identified muscle cells of Drosophila larvae
    • Johansen J, Halpern ME, Johansen KM, Keshishian H. 1989. Stereotypic morphology of glutamatergic synapses on identified muscle cells of Drosophila larvae. J Neurosci 9:710-725.
    • (1989) J Neurosci , vol.9 , pp. 710-725
    • Johansen, J.1    Halpern, M.E.2    Johansen, K.M.3    Keshishian, H.4
  • 31
    • 0028828226 scopus 로고
    • Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans
    • Jorgensen EM, Hartwieg E, Schuske K, Nonet ML, Jin Y, Horvitz HR. 1995. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans. Nature 378:196-199.
    • (1995) Nature , vol.378 , pp. 196-199
    • Jorgensen, E.M.1    Hartwieg, E.2    Schuske, K.3    Nonet, M.L.4    Jin, Y.5    Horvitz, H.R.6
  • 33
    • 0032981938 scopus 로고    scopus 로고
    • Contribution of active zone subpopulation of vesicles to evoked and spontaneous release
    • Koenig JH, Ikeda K. 1999. Contribution of active zone subpopulation of vesicles to evoked and spontaneous release. J Neurophysiol 81:1495-1505.
    • (1999) J Neurophysiol , vol.81 , pp. 1495-1505
    • Koenig, J.H.1    Ikeda, K.2
  • 34
    • 0027233507 scopus 로고
    • Calcium-induced translocation of synaptic vesicles to the active site
    • Koenig JH, Yamaoka K, Ikeda K. 1993. Calcium-induced translocation of synaptic vesicles to the active site. J Neurosci 13:2313-2322.
    • (1993) J Neurosci , vol.13 , pp. 2313-2322
    • Koenig, J.H.1    Yamaoka, K.2    Ikeda, K.3
  • 35
    • 0020603664 scopus 로고
    • Possible temperature-dependent blockage of synaptic vesicle recycling induced by a single gene mutation in Drosophila
    • Kosaka T, Ikeda K. 1983. Possible temperature-dependent blockage of synaptic vesicle recycling induced by a single gene mutation in Drosophila. J Neurobiol 14:207-225.
    • (1983) J Neurobiol , vol.14 , pp. 207-225
    • Kosaka, T.1    Ikeda, K.2
  • 36
    • 0028973239 scopus 로고
    • 2+ sensors for the fast and slow components of neurotransmitter release
    • 2+ sensors for the fast and slow components of neurotransmitter release. J Biol Chem 270:24898-24902.
    • (1995) J Biol Chem , vol.270 , pp. 24898-24902
    • Li, C.1    Davletov, B.A.2    Südhof, T.C.3
  • 39
    • 0027974130 scopus 로고
    • Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
    • Littleton JT, Stern M, Perin M, Bellen HJ. 1994. Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants. Proc Natl Acad Sci U S A 91:10888-10892.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10888-10892
    • Littleton, J.T.1    Stern, M.2    Perin, M.3    Bellen, H.J.4
  • 40
    • 0033584339 scopus 로고    scopus 로고
    • Synaptic function modulated by changes in the ratio of synaptotagmin I and IV
    • Littleton JT, Serano TL, Rubin GM, Ganetzky B, Chapman ER. 1999. Synaptic function modulated by changes in the ratio of synaptotagmin I and IV. Nature 400:757-760.
    • (1999) Nature , vol.400 , pp. 757-760
    • Littleton, J.T.1    Serano, T.L.2    Rubin, G.M.3    Ganetzky, B.4    Chapman, E.R.5
  • 42
    • 0019350409 scopus 로고
    • Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse
    • Llinás R, Steinberg IZ, Walton K. 1981. Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse. Biophys J 33:323-351.
    • (1981) Biophys J , vol.33 , pp. 323-351
    • Llinás, R.1    Steinberg, I.Z.2    Walton, K.3
  • 44
    • 0034806060 scopus 로고    scopus 로고
    • Drosophila synaptotagmin I null mutants survive to early adulthood
    • Loewen CA, Mackler JM, Reist NE. 2001. Drosophila synaptotagmin I null mutants survive to early adulthood. Genesis 31:30-36.
    • (2001) Genesis , vol.31 , pp. 30-36
    • Loewen, C.A.1    Mackler, J.M.2    Reist, N.E.3
  • 45
    • 0035898066 scopus 로고    scopus 로고
    • 2 domain of synaptotagmin disrupt synaptic transmission at Drosophila neuromuscular junctions
    • 2 domain of synaptotagmin disrupt synaptic transmission at Drosophila neuromuscular junctions. J Comp Neurol 436:4-16.
    • (2001) J Comp Neurol , vol.436 , pp. 4-16
    • Mackler, J.M.1    Reist, N.E.2
  • 47
    • 0037157825 scopus 로고    scopus 로고
    • Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I
    • Mahal LK, Sequeira SM, Gureasko JM, Söllner TH. 2002. Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I. J Cell Biol 158:273-282.
    • (2002) J Cell Biol , vol.158 , pp. 273-282
    • Mahal, L.K.1    Sequeira, S.M.2    Gureasko, J.M.3    Söllner, T.H.4
  • 48
    • 0037187635 scopus 로고    scopus 로고
    • Prime movers of synaptic vesicle exocytosis
    • Martin TF. 2002. Prime movers of synaptic vesicle exocytosis. Neuron 34:9-12.
    • (2002) Neuron , vol.34 , pp. 9-12
    • Martin, T.F.1
  • 49
    • 9344268267 scopus 로고    scopus 로고
    • Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I
    • Nicholson-Tomishima K, Ryan TA. 2004. Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I. Proc Natl Acad Sci U S A 101:16648-16652.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16648-16652
    • Nicholson-Tomishima, K.1    Ryan, T.A.2
  • 50
    • 3042796387 scopus 로고    scopus 로고
    • Synaptotagmin I synchronizes transmitter release in mouse hippocampal neurons
    • Nishiki T, Augustine GJ. 2004. Synaptotagmin I synchronizes transmitter release in mouse hippocampal neurons. J Neurosci 24:6127-6132.
    • (2004) J Neurosci , vol.24 , pp. 6127-6132
    • Nishiki, T.1    Augustine, G.J.2
  • 51
    • 0027319325 scopus 로고
    • Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotag-min
    • Nonet ML, Grundahl K, Meyer BJ, Rand JB. 1993. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotag-min. Cell 73:1291-1305.
    • (1993) Cell , vol.73 , pp. 1291-1305
    • Nonet, M.L.1    Grundahl, K.2    Meyer, B.J.3    Rand, J.B.4
  • 52
    • 0026088029 scopus 로고
    • Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans
    • Perin MS, Johnston PA, Ozcelik T, Jahn R, Francke U, Südhof TC. 1991. Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans. J Biol Chem 266:615-622.
    • (1991) J Biol Chem , vol.266 , pp. 615-622
    • Perin, M.S.1    Johnston, P.A.2    Ozcelik, T.3    Jahn, R.4    Francke, U.5    Südhof, T.C.6
  • 53
    • 0346874341 scopus 로고    scopus 로고
    • Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo
    • Poskanzer KE, Marek KW, Sweeney ST, Davis GW. 2003. Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature 426:559-563.
    • (2003) Nature , vol.426 , pp. 559-563
    • Poskanzer, K.E.1    Marek, K.W.2    Sweeney, S.T.3    Davis, G.W.4
  • 54
    • 0023491928 scopus 로고
    • Correlations between active zone ultrastructure and synaptic function studied with freeze-fracture of physiologically identified neuromuscular junctions
    • Propst JW, Ko CP. 1987. Correlations between active zone ultrastructure and synaptic function studied with freeze-fracture of physiologically identified neuromuscular junctions. J Neurosci 7:3654-3664.
    • (1987) J Neurosci , vol.7 , pp. 3654-3664
    • Propst, J.W.1    Ko, C.P.2
  • 55
    • 0032188811 scopus 로고    scopus 로고
    • Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila
    • Reist NE, Buchanan J, Li J, DiAntonio A, Buxton EM, Schwarz TL. 1998. Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila. J Neurosci 18:7662-7673.
    • (1998) J Neurosci , vol.18 , pp. 7662-7673
    • Reist, N.E.1    Buchanan, J.2    Li, J.3    Diantonio, A.4    Buxton, E.M.5    Schwarz, T.L.6
  • 58
    • 0029990813 scopus 로고    scopus 로고
    • Timing of neurotransmission at fast synapses in the mammalian brain
    • Sabatini BL, Regehr WG. 1996. Timing of neurotransmission at fast synapses in the mammalian brain. Nature 384:170-172.
    • (1996) Nature , vol.384 , pp. 170-172
    • Sabatini, B.L.1    Regehr, W.G.2
  • 59
  • 60
    • 0031019926 scopus 로고    scopus 로고
    • Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses
    • Schiavo G, Stenbeck G, Rothman JE, Söllner TH. 1997. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc Natl Acad Sci U S A 94:997-1001.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 997-1001
    • Schiavo, G.1    Stenbeck, G.2    Rothman, J.E.3    Söllner, T.H.4
  • 62
    • 0028483237 scopus 로고
    • Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions
    • Stewart BA, Atwood HL, Renger JJ, Wang J, Wu CF. 1994. Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol A175:179-191.
    • (1994) J Comp Physiol , vol.A175 , pp. 179-191
    • Stewart, B.A.1    Atwood, H.L.2    Renger, J.J.3    Wang, J.4    Wu, C.F.5
  • 63
    • 20044389482 scopus 로고    scopus 로고
    • Disruption of synaptic development and ultrastructure by Drosophila NSF2 alleles
    • Stewart BA, Pearce J, Bajec M, Khorana R. 2005. Disruption of synaptic development and ultrastructure by Drosophila NSF2 alleles. J Comp Neurol 488:101-111.
    • (2005) J Comp Neurol , vol.488 , pp. 101-111
    • Stewart, B.A.1    Pearce, J.2    Bajec, M.3    Khorana, R.4
  • 64
    • 2942556680 scopus 로고    scopus 로고
    • The synaptic vesicle cycle
    • Südhof TC. 2004. The synaptic vesicle cycle. Annu Rev Neurosci 27:509-547.
    • (2004) Annu Rev Neurosci , vol.27 , pp. 509-547
    • Südhof, T.C.1
  • 67
    • 1942520207 scopus 로고    scopus 로고
    • 2+-regulated membrane fusion by synaptotagmin and SNAREs
    • 2+-regulated membrane fusion by synaptotagmin and SNAREs. Science 304:435-438.
    • (2004) Science , vol.304 , pp. 435-438
    • Tucker, W.C.1    Weber, T.2    Chapman, E.R.3
  • 69
    • 0142073725 scopus 로고    scopus 로고
    • Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling
    • Virmani T, Han W, Liu X, Südhof TC, Kavalali ET. 2003. Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling. EMBO J 22:5347-5357.
    • (2003) EMBO J , vol.22 , pp. 5347-5357
    • Virmani, T.1    Han, W.2    Liu, X.3    Südhof, T.C.4    Kavalali, E.T.5
  • 70
    • 0035949679 scopus 로고    scopus 로고
    • Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I
    • Voets T, Moser T, Lund PE, Chow RH, Geppert M, Südhof TC, Neher E. 2001. Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I. Proc Natl Acad Sci U S A 98:11680-11685.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11680-11685
    • Voets, T.1    Moser, T.2    Lund, P.E.3    Chow, R.H.4    Geppert, M.5    Südhof, T.C.6    Neher, E.7
  • 73
    • 0037598589 scopus 로고    scopus 로고
    • Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release
    • Wucherpfennig T, Wilsch-Bräuninger M, González-Gaitán M. 2003. Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol 161:609-624.
    • (2003) J Cell Biol , vol.161 , pp. 609-624
    • Wucherpfennig, T.1    Wilsch-Bräuninger, M.2    González-Gaitán, M.3
  • 74
    • 0037027739 scopus 로고    scopus 로고
    • Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release
    • Yoshihara M, Littleton JT. 2002. Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release. Neuron 36:897-908.
    • (2002) Neuron , vol.36 , pp. 897-908
    • Yoshihara, M.1    Littleton, J.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.