The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis

Journal of Cell Biology

Volumn 154, Issue 6, 2001, Pages 1117-1123

  Earles, Cynthia A ^a   Bai, Jihong ^a   Wang, Ping ^a   Chapman, Edwin R ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

C2 domain; Exocytosis; membrane fusion; SNARE; synaptotagmin

Indexed keywords

CALCIUM ION; SNARE PROTEIN; SYNAPTOTAGMIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM BINDING; CONTROLLED STUDY; EXOCYTOSIS; GENE MUTATION; MEMBRANE FUSION; NONHUMAN; POTENTIOMETRY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM;

ANIMALS; BINDING SITES; CALCIUM; CALCIUM-BINDING PROTEINS; ELECTROCHEMISTRY; EXOCYTOSIS; LIGANDS; MEMBRANE FUSION; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NOREPINEPHRINE; PC12 CELLS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SNARE PROTEINS; SYNAPTOTAGMIN I; SYNAPTOTAGMINS; VESICULAR TRANSPORT PROTEINS;

ANIMALIA;

EID: 0035904238     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200105020     Document Type: Article

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