Characterization of the spontaneous "aging" of the heme oxygenase from the pathological bacterium Neisseria meningitidis via cleavage of the C-terminus in contact with the substrate. Implications for functional studies and the crystal structure

Biochemistry

Volumn 45, Issue 12, 2006, Pages 3875-3886

  Liu, Yangzhong ^a   Ma, Li Hua ^a   Zhang, Xuhong ^b   Yoshida, Tadashi ^b   Satterlee, James D ^c   La Mar, Gerd N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YAMAGATA UNIVERSITY   (Japan)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CRYSTAL STRUCTURE; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; SUBSTRATES;

C-TERMINAL INTERACTION; HEME OXYGENASE; NEISSERIA MENINGITIDIS; TERMINAL SEQUENCING;

ENZYMES;

ALPHA BILIVERDIN; ARGININE; BILIVERDIN; CYANIDE; DEFEROXAMINE; DIPEPTIDE; HEME OXYGENASE; HEMIN; HISTIDINE; PYRROLE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM MUTANT; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DELETION MUTANT; HALF LIFE TIME; LIGAND BINDING; MASS SPECTROMETRY; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; HEME OXYGENASE (DECYCLIZING); MODELS, MOLECULAR; NEISSERIA MENINGITIDIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); NEISSERIA MENINGITIDIS;

EID: 33645450509     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0523097     Document Type: Article

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