-
1
-
-
0023775222
-
Ferritin: An iron storage protein with diverse functions
-
Joshi J.G., Clauberg M. Ferritin: an iron storage protein with diverse functions. Biofactors. 3:1988;207-212.
-
(1988)
Biofactors
, vol.3
, pp. 207-212
-
-
Joshi, J.G.1
Clauberg, M.2
-
2
-
-
0014348401
-
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
-
Tenhunen R., Marver H.S., Schmid R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl Acad. Sci. USA. 61:1968;748-755.
-
(1968)
Proc. Natl Acad. Sci. USA
, vol.61
, pp. 748-755
-
-
Tenhunen, R.1
Marver, H.S.2
Schmid, R.3
-
3
-
-
0014670945
-
Microsomal heme oxygenase. Characterization of the enzyme
-
Tenhunen R., Marver H.S., Schmid R. Microsomal heme oxygenase. Characterization of the enzyme. J. Biol. Chem. 244:1969;6388-6394.
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6388-6394
-
-
Tenhunen, R.1
Marver, H.S.2
Schmid, R.3
-
4
-
-
0542422859
-
Heme oxygenase mechanism: Evidence for an electrophilic ferric peroxide species
-
Ortiz de Montellano P.R. Heme oxygenase mechanism: evidence for an electrophilic ferric peroxide species. Acc. Chem. Res. 31:1998;543-549.
-
(1998)
Acc. Chem. Res.
, vol.31
, pp. 543-549
-
-
Ortiz de Montellano, P.R.1
-
7
-
-
0040141555
-
Reaction intermediates and single turnover rate constants for the oxidation of heme by human heme oxygenase-1
-
Liu Y., Ortiz de Montellano P.R. Reaction intermediates and single turnover rate constants for the oxidation of heme by human heme oxygenase-1. J. Biol. Chem. 275:2000;5297-5307.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5297-5307
-
-
Liu, Y.1
Ortiz de Montellano, P.R.2
-
8
-
-
0017900548
-
Features of the reaction of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system
-
Yoshida T., Kikuchi G. Features of the reaction of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system. J. Biol. Chem. 253:1978;4230-4236.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 4230-4236
-
-
Yoshida, T.1
Kikuchi, G.2
-
9
-
-
0017850764
-
Purification and properties of heme oxygenase from pig spleen microsomes
-
Yoshida T., Kikuchi G. Purification and properties of heme oxygenase from pig spleen microsomes. J. Biol. Chem. 253:1978;4224-4229.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 4224-4229
-
-
Yoshida, T.1
Kikuchi, G.2
-
10
-
-
0023731036
-
Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
-
Maines M.D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2:1988;2557-2568.
-
(1988)
FASEB J.
, vol.2
, pp. 2557-2568
-
-
Maines, M.D.1
-
11
-
-
0015501157
-
Immunochemical evidence for an association of heme oxygenase with the microsomal electron transport system
-
Schacter B., Nelson E., Marver H., Masters B.S. Immunochemical evidence for an association of heme oxygenase with the microsomal electron transport system. J. Biol. Chem. 247:1972;3601-3607.
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 3601-3607
-
-
Schacter, B.1
Nelson, E.2
Marver, H.3
Masters, B.S.4
-
12
-
-
0019332526
-
Oxygenated form of heme-heme oxygenase complex and requirement for second electron to initiate heme degradation from the oxygenated complex
-
Yoshida T., Noguchi M., Kikuchi G. Oxygenated form of heme-heme oxygenase complex and requirement for second electron to initiate heme degradation from the oxygenated complex. J. Biol. Chem. 255:1980;4418-4420.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 4418-4420
-
-
Yoshida, T.1
Noguchi, M.2
Kikuchi, G.3
-
14
-
-
0033980283
-
The heme oxygenase-carbon monoxide system: A regulator of hepatobilary function
-
Suematsu M., Ishimura Y. The heme oxygenase-carbon monoxide system: a regulator of hepatobilary function. Hepatology. 31:2000;3-6.
-
(2000)
Hepatology
, vol.31
, pp. 3-6
-
-
Suematsu, M.1
Ishimura, Y.2
-
15
-
-
0003514551
-
-
H.B. Dunford. New York: Wiley/VCH
-
Dunford H.B. Dunford H.B. Heme Peroxidases. 1999;Wiley/VCH, New York.
-
(1999)
Heme Peroxidases
-
-
Dunford, H.B.1
-
16
-
-
0019321508
-
The stereochemistry of peroxidase catalysis
-
Poulos T.L., Kraut J. The stereochemistry of peroxidase catalysis. J. Biol. Chem. 255:1980;8199-8205.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 8199-8205
-
-
Poulos, T.L.1
Kraut, J.2
-
18
-
-
0027440198
-
Rat liver heme oxygenase. High level expression of a truncated soluble form and nature of the meso-hydroxylating species
-
Wilks A., Ortiz de Montellano P.R. Rat liver heme oxygenase. High level expression of a truncated soluble form and nature of the meso-hydroxylating species. J. Biol. Chem. 268:1993;22357-22362.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22357-22362
-
-
Wilks, A.1
Ortiz de Montellano, P.R.2
-
19
-
-
0027998288
-
Heme oxygenase HO-1. Evidence for electrophilic oxygen addition to the porphyrin ring in the formation of alpha-meso-hydroxyheme
-
Wilks A., Torpey J., Ortiz de Montellano P.R. Heme oxygenase HO-1. Evidence for electrophilic oxygen addition to the porphyrin ring in the formation of alpha-meso-hydroxyheme. J. Biol. Chem. 269:1994;29553-29556.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29553-29556
-
-
Wilks, A.1
Torpey, J.2
Ortiz de Montellano, P.R.3
-
20
-
-
10244247769
-
Oxidation of the meso-methylmesoheme regioisomers by heme oxygenase
-
Torpey J., Ortiz de Montellano P.R. Oxidation of the meso-methylmesoheme regioisomers by heme oxygenase. J. Biol. Chem. 271:1996;26067-26073.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26067-26073
-
-
Torpey, J.1
Ortiz de Montellano, P.R.2
-
21
-
-
0030881920
-
Oxidation of α-meso-formylmesoheme by heme oxygenase
-
Torpey J., Ortiz de Montellano P.R. Oxidation of α-meso-formylmesoheme by heme oxygenase. J. Biol. Chem. 272:1997;22008-22014.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22008-22014
-
-
Torpey, J.1
Ortiz de Montellano, P.R.2
-
22
-
-
0033579192
-
Hydroperoxy-heme oxygenase generated by cryoreduction catalyzes the formation of α-meso-hydroxyheme as detected by EPR and ENDOR
-
Davydov R.M., Yoshida T., Ikeda-Saito M., Hoffman B.M. Hydroperoxy-heme oxygenase generated by cryoreduction catalyzes the formation of α-meso-hydroxyheme as detected by EPR and ENDOR. J. Am. Chem. Soc. 121:1999;10656-10657.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 10656-10657
-
-
Davydov, R.M.1
Yoshida, T.2
Ikeda-Saito, M.3
Hoffman, B.M.4
-
23
-
-
0029917163
-
Oxygen and one reducing equivalent are both required for the conversion of alpha-hydroxyhemin to verdoheme in heme oxygenase
-
Matera K.M., Takahashi S., Fujii H., Zhou H., Ishikawa K., Yoshimura T., et al. Oxygen and one reducing equivalent are both required for the conversion of alpha-hydroxyhemin to verdoheme in heme oxygenase. J. Biol. Chem. 271:1996;6618-6624.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6618-6624
-
-
Matera, K.M.1
Takahashi, S.2
Fujii, H.3
Zhou, H.4
Ishikawa, K.5
Yoshimura, T.6
-
24
-
-
0030905395
-
Heme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents
-
Liu Y., Moënne-Loccoz P., Loehr T.M., Ortiz de Montellano P.R. Heme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents. J. Biol. Chem. 272:1997;6909-6917.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6909-6917
-
-
Liu, Y.1
Moënne-Loccoz, P.2
Loehr, T.M.3
Ortiz de Montellano, P.R.4
-
25
-
-
0033603348
-
Ferric α-hydroxyheme bound to heme oxygenase can be converted to verdoheme by dioxygen in the absence of added reducing equivalents
-
Sakamoto H., Omata Y., Palmer G., Noguchi M. Ferric α-hydroxyheme bound to heme oxygenase can be converted to verdoheme by dioxygen in the absence of added reducing equivalents. J. Biol. Chem. 274:1999;18196-18200.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18196-18200
-
-
Sakamoto, H.1
Omata, Y.2
Palmer, G.3
Noguchi, M.4
-
26
-
-
0009611092
-
Molecular oxygen oxidizes the porphyrin ring of the ferric α-hydroxyheme in heme oxygenase in the absence of reducing equivalents
-
Migita C.T., Fujii H., Matera K.M., Takahashi S., Zhou H., Yoshida T. Molecular oxygen oxidizes the porphyrin ring of the ferric α-hydroxyheme in heme oxygenase in the absence of reducing equivalents. Biochim. Biophys. Acta. 1432:1999;203-213.
-
(1999)
Biochim. Biophys. Acta
, vol.1432
, pp. 203-213
-
-
Migita, C.T.1
Fujii, H.2
Matera, K.M.3
Takahashi, S.4
Zhou, H.5
Yoshida, T.6
-
27
-
-
0028955429
-
Heme oxygenase-2. Properties of the heme complex of the purified tryptic fragment of recombinant human heme oxygenase-2
-
Ishikawa K., Takeuchi N., Takahashi S., Matera K.M., Sato M., Shibahara S., et al. Heme oxygenase-2. Properties of the heme complex of the purified tryptic fragment of recombinant human heme oxygenase-2. J. Biol. Chem. 270:1995;6345-6350.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6345-6350
-
-
Ishikawa, K.1
Takeuchi, N.2
Takahashi, S.3
Matera, K.M.4
Sato, M.5
Shibahara, S.6
-
28
-
-
0028967839
-
Expression and characterization of truncated human heme oxygenase hHO-1 and a fusion protein of hHO-1 with human cytochrome P450 reductase
-
Wilks A., Black S.M., Miller W.L., Ortiz de Montellano P.R. Expression and characterization of truncated human heme oxygenase hHO-1 and a fusion protein of hHO-1 with human cytochrome P450 reductase. Biochemistry. 34:1995;4421-4427.
-
(1995)
Biochemistry
, vol.34
, pp. 4421-4427
-
-
Wilks, A.1
Black, S.M.2
Miller, W.L.3
Ortiz de Montellano, P.R.4
-
30
-
-
0034616274
-
Crystal structure of rat heme oxygenase-1 in complex with heme
-
Sugishima M., Omato Y., Kakuta Y., Sakamoto H., Noguchi M., Fukuyama K. Crystal structure of rat heme oxygenase-1 in complex with heme. FEBS Letters. 471:2000;61-66.
-
(2000)
FEBS Letters
, vol.471
, pp. 61-66
-
-
Sugishima, M.1
Omato, Y.2
Kakuta, Y.3
Sakamoto, H.4
Noguchi, M.5
Fukuyama, K.6
-
31
-
-
0037424264
-
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
-
Lad L., Schuller D.J., Shimizu H., Friedman J., Li H., Ortiz de Montellano P.R., Poulos T.L. Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1. J. Biol.Chem. 278:2003;7834-7843.
-
(2003)
J. Biol.Chem.
, vol.278
, pp. 7834-7843
-
-
Lad, L.1
Schuller, D.J.2
Shimizu, H.3
Friedman, J.4
Li, H.5
Ortiz de Montellano, P.R.6
Poulos, T.L.7
-
32
-
-
0000582319
-
Oxygen-bound heme-heme oxygenase complex: Evidence for a highly bent structure of the coordinated oxygen
-
Takahashi S., Ishikawa K., Takeuchi N., Ikeda-Saito M., Yoshida T., Rousseau D.L. Oxygen-bound heme-heme oxygenase complex: evidence for a highly bent structure of the coordinated oxygen. J. Am. Chem. Soc. 117:1995;6002-6006.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 6002-6006
-
-
Takahashi, S.1
Ishikawa, K.2
Takeuchi, N.3
Ikeda-Saito, M.4
Yoshida, T.5
Rousseau, D.L.6
-
33
-
-
0346003806
-
Crystal structure of rat heme oxygenase-1 in complex with heme bound to azide: Implication for regiospecific hydroxylation of heme at the a-meso carbon
-
Sugishima M., Sakamoto H., Higashimoto Y., Omato Y., Hayashi S., Noguchi M., Fukuyama K. Crystal structure of rat heme oxygenase-1 in complex with heme bound to azide: implication for regiospecific hydroxylation of heme at the a-meso carbon. J. Biol. Chem. 277:2002;45086-45090.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45086-45090
-
-
Sugishima, M.1
Sakamoto, H.2
Higashimoto, Y.3
Omato, Y.4
Hayashi, S.5
Noguchi, M.6
Fukuyama, K.7
-
34
-
-
0035815676
-
Disruption of an active site hydrogen bond converts human heme oxygenase-1 into a peroxidase
-
Lightning L.K., Huang H., Moenne-Loccoz P., Loehr T.M., Schuller D.J., Poulos T.L., Ortiz de Montellano P.R. Disruption of an active site hydrogen bond converts human heme oxygenase-1 into a peroxidase. J. Biol. Chem. 276:2001;10612-10619.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10612-10619
-
-
Lightning, L.K.1
Huang, H.2
Moenne-Loccoz, P.3
Loehr, T.M.4
Schuller, D.J.5
Poulos, T.L.6
Ortiz de Montellano, P.R.7
-
35
-
-
0034803953
-
A role for highly conserved carboxylate, aspartate-140, in oxygen activation and heme degradation by heme oxygenase-1
-
Fujii H., Zhang H., Tomita T., Ikeda-Saito M., Yoshida T. A role for highly conserved carboxylate, aspartate-140, in oxygen activation and heme degradation by heme oxygenase-1. J. Am. Chem. Soc. 123:2001;6475-6484.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 6475-6484
-
-
Fujii, H.1
Zhang, H.2
Tomita, T.3
Ikeda-Saito, M.4
Yoshida, T.5
-
36
-
-
0035844131
-
Solution 1H NMR of the active site of substrate-bound, cyanide-inhibited, human heme oxygenase: Comparison to the crystal structure of the water-ligated form
-
La Mar G.N., Asokan A., Espiritu B., Yeh D.C., Auclair K., Ortiz de Montellano P.R. Solution 1H NMR of the active site of substrate-bound, cyanide-inhibited, human heme oxygenase: comparison to the crystal structure of the water-ligated form. J. Biol. Chem. 276:2001;15676-15687.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15676-15687
-
-
La Mar, G.N.1
Asokan, A.2
Espiritu, B.3
Yeh, D.C.4
Auclair, K.5
Ortiz de Montellano, P.R.6
-
37
-
-
0037031935
-
Solution NMR characterization of an unusual distal H-bond network in the active site of the cyanide-inhibited human heme oxygenase complex of the symmetric substrate 2,4-dimethyldeuterohemin
-
Li Y., Syvitiski R., Auclair K., Wilks A., Ortiz de Montellano P.R., La Mar G.N. Solution NMR characterization of an unusual distal H-bond network in the active site of the cyanide-inhibited human heme oxygenase complex of the symmetric substrate 2,4-dimethyldeuterohemin. J. Biol. Chem. 277:2002;33018-33031.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33018-33031
-
-
Li, Y.1
Syvitiski, R.2
Auclair, K.3
Wilks, A.4
Ortiz de Montellano, P.R.5
La Mar, G.N.6
-
38
-
-
0037021368
-
1H NMR detection of immobilized water molecules within a strong hydrogen-bonding distal network in substrate-bound human heme oxygenase
-
Syvitski R.T., Li Y., Auclair K., L Mar G.N. 1H NMR detection of immobilized water molecules within a strong hydrogen-bonding distal network in substrate-bound human heme oxygenase. J. Am. Chem. Soc. 124:2002;14296-14297.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 14296-14297
-
-
Syvitski, R.T.1
Li, Y.2
Auclair, K.3
L Mar, G.N.4
-
39
-
-
0034088779
-
The catalytic pathway of cytochrome P450 at atomic resolution
-
Schlichting L., Berendzen J., Chu K., Stock A.M., Maves S.A., Benson D.E., et al. The catalytic pathway of cytochrome P450 at atomic resolution. Science. 287:2000;1615-1622.
-
(2000)
Science
, vol.287
, pp. 1615-1622
-
-
Schlichting, L.1
Berendzen, J.2
Chu, K.3
Stock, A.M.4
Maves, S.A.5
Benson, D.E.6
-
40
-
-
0037161809
-
The catalytic pathway of horseradish peroxidase at high resolution
-
Berglund G.I., Carlsson G.H., smith A.T., Szoke H., Henriksen A., Hajdu J. The catalytic pathway of horseradish peroxidase at high resolution. Nature. 417:2002;463-468.
-
(2002)
Nature
, vol.417
, pp. 463-468
-
-
Berglund, G.I.1
Carlsson, G.H.2
Smith, A.T.3
Szoke, H.4
Henriksen, A.5
Hajdu, J.6
-
41
-
-
0034602153
-
Replacement of the distal glycine 139 transforms human heme oxygenase-1 into a peroxidase
-
Liu Y., Lightening L.K., Huang H., Moenne-Loccoz P., Schuller D.J., Poulos T.L., et al. Replacement of the distal glycine 139 transforms human heme oxygenase-1 into a peroxidase. J. Biol. Chem. 275:2000;34501-34507.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34501-34507
-
-
Liu, Y.1
Lightening, L.K.2
Huang, H.3
Moenne-Loccoz, P.4
Schuller, D.J.5
Poulos, T.L.6
-
42
-
-
0037181030
-
Catalytic mechanism of heme oxygenase through EPR and ENDOR of cryoreduced oxy-heme oxygenase and its Asp 140 mutants
-
Davydov R., Kofman V., Fujii H., Yoshida T., Ikeda-Saito M., Hoffman B.M. Catalytic mechanism of heme oxygenase through EPR and ENDOR of cryoreduced oxy-heme oxygenase and its Asp 140 mutants. J. Am. Chem. Soc. 124:2002;1798-1808.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 1798-1808
-
-
Davydov, R.1
Kofman, V.2
Fujii, H.3
Yoshida, T.4
Ikeda-Saito, M.5
Hoffman, B.M.6
-
43
-
-
0037140787
-
Models of the low-spin iron (III) hyderperoxide intermediate of heme oxygenase: Magnetic resonance evidence for thermodynamic stabilization of the dxy electronic state at ambient temperatures
-
Rivera M., Caignan G.A., Astashkin A.V., Raitsimring A.M., Shokhireva T.K., Ann Walker F. Models of the low-spin iron (III) hyderperoxide intermediate of heme oxygenase: magnetic resonance evidence for thermodynamic stabilization of the dxy electronic state at ambient temperatures. J. Am. Chem. Soc. 124:2002;6077-6089.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 6077-6089
-
-
Rivera, M.1
Caignan, G.A.2
Astashkin, A.V.3
Raitsimring, A.M.4
Shokhireva, T.K.5
Ann Walker, F.6
-
46
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:1997;307-326.
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
47
-
-
84920325457
-
AMoRe: An automated package for molecular replacement
-
Navanza J. AMoRe: an automated package for molecular replacement. Acta Crystallog. sect. A. 54:1994;157-163.
-
(1994)
Acta Crystallog. sect. A
, vol.54
, pp. 157-163
-
-
Navanza, J.1
-
48
-
-
3543012707
-
Crystallography and NMR system: A new software suite for macromolecular structure determination
-
Brunger A.T., Adams P.D., Clore G.M., Delano W.L., Gros P., Grosse-Kunstleve R.W., et al. Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Crystallog. sect. D. 54:1998;905-921.
-
(1998)
Acta Crystallog. sect. D
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
-
49
-
-
4243384884
-
Improved methods for binding protein models in electron density maps and the location of errors in these models
-
Jones T.A., Zou J.Y., Cowan S.W., Kieldgaard M. Improved methods for binding protein models in electron density maps and the location of errors in these models. Acta Crystallog. sect. D. 54:1991;1017-1019.
-
(1991)
Acta Crystallog. sect. D
, vol.54
, pp. 1017-1019
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kieldgaard, M.4
-
51
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structure
-
Kraulis P.J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structure. J. Appl. Crystallog. 24:1991;946-950.
-
(1991)
J. Appl. Crystallog.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
52
-
-
0030815133
-
Raster3D - Photorealistic molecular graphics
-
Merritt E.A., Bacon D.J. Raster3D - photorealistic molecular graphics. Methods Enzymol. 277:1997;505-524.
-
(1997)
Methods Enzymol.
, vol.277
, pp. 505-524
-
-
Merritt, E.A.1
Bacon, D.J.2
|