Solution 1H NMR investigation of the molecular and electronic structure of the active site of substrate-bound human heme oxygenase: The nature of the distal hydrogen bond donor to bound ligands

Journal of the American Chemical Society

Volumn 120, Issue 34, 1998, Pages 8875-8884

  Gorst, Carol M ^a   Wilks, Angela ^b   Yeh, Deok Cheon ^a   Ortiz De Montellano, Paul R ^b   La Mar, Gerd N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEME OXYGENASE;

ARTICLE; CHEMICAL BINDING; ENZYME ANALYSIS; ENZYME SUBSTRATE COMPLEX; HUMAN; HYDROGEN BOND; LIGAND BINDING; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

EID: 0032475409     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9815475     Document Type: Article

References (66)

1. Abbreviations used: hHO, human heme oxygenase-1; rHO, rat heme oxygenase-1; HO-1, heme oxygenase isoform 1; TOCSY, 2D total correlation spectroscopy; NOESY, 2D nuclear Overhauser spectroscopy; Mb, myoglobin; PH, protohemin IX; WEFT, water-eliminated Fourier transform.
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