MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome

European Journal of Neuroscience

Volumn 23, Issue 7, 2006, Pages 1766-1774

  Zeng, B Y ^a   Iravani, M M ^a   Lin, S T ^a   Irifune, M ^a   Kuoppamaki M ^a   Al Barghouthy, G ^a   Smith, L ^a   Jackson, M J ^a   Rose, S ^a   Medhurst, A D ^b   Jenner, P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Common marmoset; MPTP; Parkinson's disease; Proteasome activity; Proteasome subunits; Ubiquitin proteasome pathway

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CHYMOTRYPSIN; PEPTIDE HYDROLASE; PROTEASOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRYPSIN; TYROSINE 3 MONOOXYGENASE; UBIQUITIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL DEATH; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; GLOBUS PALLIDUS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MARMOSET; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; WESTERN BLOTTING;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; BLOTTING, WESTERN; BRAIN; CALLITHRIX; IMMUNOHISTOCHEMISTRY; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; TYROSINE 3-MONOOXYGENASE;

EID: 33645450436     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04718.x     Document Type: Article

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