메뉴 건너뛰기




Volumn 22, Issue 7, 1998, Pages 619-623

Effect of the antiobesity agent sibutramine in obese-diabetic ob/ob mice

Author keywords

Body weight; Fatty acids; Glucose; Insulin resistance; Obese diabetic ob ob mice; Sibutramine

Indexed keywords

ANTIOBESITY AGENT; FATTY ACID; GLUCOSE; INSULIN; NORADRENALIN; SEROTONIN; SIBUTRAMINE;

EID: 0031837935     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800636     Document Type: Article
Times cited : (51)

References (24)
  • 1
    • 0023814888 scopus 로고
    • The pharmacology of sibutramine hydrochloride (BTRS 54524), a new antidepressant which induces rapid noradrenergic down-regulation
    • Buckett WR, Thomas PC, Luscombe GP. The pharmacology of sibutramine hydrochloride (BTRS 54524), a new antidepressant which induces rapid noradrenergic down-regulation. Prog Neuropsychopharmacol Bio Psychiatry 1988; 12: 575-584.
    • (1988) Prog Neuropsychopharmacol Bio Psychiatry , vol.12 , pp. 575-584
    • Buckett, W.R.1    Thomas, P.C.2    Luscombe, G.P.3
  • 4
    • 0001612783 scopus 로고
    • Effects in the rat of sibutramine on food intake and the behavioural satiety sequence
    • Halford JCG, Heal DJ, Blundell JE. Effects in the rat of sibutramine on food intake and the behavioural satiety sequence. Br J Pharmacol 1995; 114: 387P
    • (1995) Br J Pharmacol , vol.114
    • Halford, J.C.G.1    Heal, D.J.2    Blundell, J.E.3
  • 5
    • 0000115414 scopus 로고
    • A study in rats of the effects of sibutramine on food intake and thermogenesis
    • Connoley IP, Heal DJ, Stock MJ. A study in rats of the effects of sibutramine on food intake and thermogenesis. Br J Pharmacol 1995; 114: 388P.
    • (1995) Br J Pharmacol , vol.114
    • Connoley, I.P.1    Heal, D.J.2    Stock, M.J.3
  • 8
    • 0002864396 scopus 로고    scopus 로고
    • Animal syndromes of non-insulin-dependent diabetes mellitus
    • Pickup JC, Williams G (eds). Blackwell Science: Oxford
    • Bailey CJ, Flatt PR. Animal syndromes of non-insulin-dependent diabetes mellitus. In: Pickup JC, Williams G (eds). Textbook of Diabetes (2nd edn). Blackwell Science: Oxford, 1997, pp23.1-23.25.
    • (1997) Textbook of Diabetes (2nd Edn) , pp. 231-2325
    • Bailey, C.J.1    Flatt, P.R.2
  • 10
    • 0019471997 scopus 로고
    • Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice
    • Flatt PR, Bailey CJ. Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice. Diabetologia 1981; 20: 573-577.
    • (1981) Diabetologia , vol.20 , pp. 573-577
    • Flatt, P.R.1    Bailey, C.J.2
  • 11
    • 0020086017 scopus 로고
    • Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice
    • Bailey CJ, Flatt PR, Atkins TW. Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice. Int J Obes 1982; 6: 11-21.
    • (1982) Int J Obes , vol.6 , pp. 11-21
    • Bailey, C.J.1    Flatt, P.R.2    Atkins, T.W.3
  • 12
    • 0022531205 scopus 로고
    • Anorectic effect of metformin in lean and genetically obese hyperglycaemic (ob/ob) mice
    • Bailey CJ, Flatt PR, Ewan C. Anorectic effect of metformin in lean and genetically obese hyperglycaemic (ob/ob) mice. Arch Int Pharmacodyn 1986; 282: 233-239.
    • (1986) Arch Int Pharmacodyn , vol.282 , pp. 233-239
    • Bailey, C.J.1    Flatt, P.R.2    Ewan, C.3
  • 13
    • 0015038855 scopus 로고
    • Determination of glucose by an automatic analyser
    • Stevens JF. Determination of glucose by an automatic analyser. Clin Chim Acta 1971; 32: 199-201.
    • (1971) Clin Chim Acta , vol.32 , pp. 199-201
    • Stevens, J.F.1
  • 14
    • 0019444348 scopus 로고
    • Development of glucose intolerance and impaired plasma insulin response to glucose in obese hyperglycaemic (ob/ob) mice
    • Flatt PR, Bailey CJ. Development of glucose intolerance and impaired plasma insulin response to glucose in obese hyperglycaemic (ob/ob) mice. Horm Metab Res 1981; 13: 556-560.
    • (1981) Horm Metab Res , vol.13 , pp. 556-560
    • Flatt, P.R.1    Bailey, C.J.2
  • 15
    • 0022445303 scopus 로고
    • Anorectic effect of fenfluramine. cholecystokinin and neurotensin in genetically obese (ob/ob) mice
    • Bailey CJ, Flatt PR. Anorectic effect of fenfluramine. cholecystokinin and neurotensin in genetically obese (ob/ob) mice. Comp Biochem Physiol 1986; 84A: 451-454.
    • (1986) Comp Biochem Physiol , vol.84 A , pp. 451-454
    • Bailey, C.J.1    Flatt, P.R.2
  • 16
    • 0020549632 scopus 로고
    • Glucose and insulin response to conditioned feeding in lean and genetically obese hyperglycemic (ob/ob) mice
    • Flatt PR, Bailey CJ. Glucose and insulin response to conditioned feeding in lean and genetically obese hyperglycemic (ob/ob) mice. Metabolism 1983; 32: 504-509.
    • (1983) Metabolism , vol.32 , pp. 504-509
    • Flatt, P.R.1    Bailey, C.J.2
  • 17
    • 0030759773 scopus 로고    scopus 로고
    • Investiation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenuline reuptake inhibitor, sibutramine, in the rat
    • Jackson HC, Bearham MC, Hutchins LJ, Mazurkiewicz SE, Needham AM, Heal DJ. Investiation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenuline reuptake inhibitor, sibutramine, in the rat. Br J Pharmacol 1997; 121: 1613-1618.
    • (1997) Br J Pharmacol , vol.121 , pp. 1613-1618
    • Jackson, H.C.1    Bearham, M.C.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Needham, A.M.5    Heal, D.J.6
  • 18
    • 0344128955 scopus 로고    scopus 로고
    • The central nervous system and diabetes mellitus
    • Pickup JC, Williams G (eds). Blackwell Science: Oxford
    • Williams G, Wilding J. The central nervous system and diabetes mellitus. In: Pickup JC, Williams G (eds). Textbook of Diabetes (2nd edn). Blackwell Science: Oxford, 1997, pp 65.1-65.30.
    • (1997) Textbook of Diabetes (2nd Edn) , pp. 651-6530
    • Williams, G.1    Wilding, J.2
  • 20
    • 0001071783 scopus 로고    scopus 로고
    • Role of β-adrenoceptors in mediating the thermogenic effects of sibutramine
    • Connoley IP, Frost I, Heal DJ, Stock MJ. Role of β-adrenoceptors in mediating the thermogenic effects of sibutramine. Br J Pharmacol 1996; 116: 170.
    • (1996) Br J Pharmacol , vol.116 , pp. 170
    • Connoley, I.P.1    Frost, I.2    Heal, D.J.3    Stock, M.J.4
  • 21
    • 0000574594 scopus 로고
    • Body composition changes following weight loss induced by sibutramine
    • Griffiths J, Bloom SR, Finer N, Jones SP, Romance FM. Body composition changes following weight loss induced by sibutramine. Int J Obes 1995; 19 (Suppl 2): 144.
    • (1995) Int J Obes , vol.19 , Issue.2 SUPPL. , pp. 144
    • Griffiths, J.1    Bloom, S.R.2    Finer, N.3    Jones, S.P.4    Romance, F.M.5
  • 22
    • 0003117454 scopus 로고
    • Obesity and nutritional factors in the pathogenesis of non-insulin-dependent diabetes mellitus
    • Pickup JC, Williams G (eds). Blackwell Science: Oxford
    • Jung RT. Obesity and nutritional factors in the pathogenesis of non-insulin-dependent diabetes mellitus. In: Pickup JC, Williams G (eds). Textbook of Diabetes (2nd edn) Blackwell Science: Oxford, 1991, pp 19.1-19.23.
    • (1991) Textbook of Diabetes (2nd Edn) , pp. 191-1923
    • Jung, R.T.1
  • 23
    • 0028129690 scopus 로고
    • Chronic fenfluramine treatment: Effects on body weight, food intake and energy expenditure
    • Stallone DD, Levitsky DA. Chronic fenfluramine treatment: effects on body weight, food intake and energy expenditure. Int J Obes 1994; 18: 679-685.
    • (1994) Int J Obes , vol.18 , pp. 679-685
    • Stallone, D.D.1    Levitsky, D.A.2
  • 24
    • 0022599255 scopus 로고
    • Effects of ephedrine and atenolol on the development of obesity and diabetes in ob/ob mice
    • Bailey CJ, Thomburn CC, Flatt PR. Effects of ephedrine and atenolol on the development of obesity and diabetes in ob/ob mice. Gen Pharmac 1986; 17: 243-246.
    • (1986) Gen Pharmac , vol.17 , pp. 243-246
    • Bailey, C.J.1    Thomburn, C.C.2    Flatt, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.