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Volumn 172, Issue 3, 2006, Pages 1411-1425

Estimating diversifying selection and functional constraint in the presence of recombination

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BAYES THEOREM; CODON; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC VARIABILITY; MATHEMATICAL MODEL; MOLECULAR EVOLUTION; MOLECULAR MODEL; NEISSERIA MENINGITIDIS; NONHUMAN; PHYLOGENETIC TREE CONSTRUCTION METHOD; POPULATION GENETIC PARAMETERS; PORB GENE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIMULATION;

EID: 33645229840     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.105.044917     Document Type: Article
Times cited : (214)

References (58)
  • 1
    • 0034897709 scopus 로고    scopus 로고
    • Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution
    • ANISIMOVA, M., J. P. BIELAWSKI and Z. YANG, 2001 Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution. Mol. Biol. Evol. 18: 1585-1592.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 1585-1592
    • Anisimova, M.1    Bielawski, J.P.2    Yang, Z.3
  • 2
    • 0036272936 scopus 로고    scopus 로고
    • Accuracy and power of Bayes prediction of amino acid sites under positive selection
    • ANISIMOVA, M., J. P. BIELAWSKI and Z. YANG, 2002 Accuracy and power of Bayes prediction of amino acid sites under positive selection. Mol. Biol. Evol. 19: 950-958.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 950-958
    • Anisimova, M.1    Bielawski, J.P.2    Yang, Z.3
  • 3
    • 0042208362 scopus 로고    scopus 로고
    • Effect of recombination on the accuracy of the likelihood method for detecting positive selection at amino acid sites
    • ANISIMOVA, M., R. NIELSEN and Z. YANG, 2003 Effect of recombination on the accuracy of the likelihood method for detecting positive selection at amino acid sites. Genetics 164: 1229-1236.
    • (2003) Genetics , vol.164 , pp. 1229-1236
    • Anisimova, M.1    Nielsen, R.2    Yang, Z.3
  • 4
    • 0037223888 scopus 로고    scopus 로고
    • The evolutionary genomics of pathogen recombination
    • AWADALLA, P., 2003 The evolutionary genomics of pathogen recombination. Nat. Rev. Genet. 4: 50-60.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 50-60
    • Awadalla, P.1
  • 5
    • 0034625046 scopus 로고    scopus 로고
    • Rapid evolution in plant chitinases: Molecular targets of selection in plant-pathogen coevolution
    • USA
    • BISHOP, J. G., A. M. DEAN and T. MITCHELL-OLDS, 2000 Rapid evolution in plant chitinases: molecular targets of selection in plant-pathogen coevolution. Proc. Natl. Acad. Sci. USA 97: 5322-5327.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 5322-5327
    • Bishop, J.G.1    Dean, A.M.2    Mitchell-Olds, T.3
  • 6
    • 0035986890 scopus 로고    scopus 로고
    • Bayesian model adequacy and choice in phylogenetics
    • BOLLBACK, J. P., 2002 Bayesian model adequacy and choice in phylogenetics. Mol. Biol. Evol. 19: 1171-1180.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1171-1180
    • Bollback, J.P.1
  • 7
    • 33645024781 scopus 로고    scopus 로고
    • Posterior mapping and posterior predictive distributions
    • edited by R. NIELSEN. Springer-Verlag, New York
    • BOLLBACK, J. P., 2005 Posterior mapping and posterior predictive distributions, pp. 439-462 in Statistical Methods in Molecular Evolution, edited by R. NIELSEN. Springer-Verlag, New York.
    • (2005) Statistical Methods in Molecular Evolution , pp. 439-462
    • Bollback, J.P.1
  • 8
    • 3843062475 scopus 로고    scopus 로고
    • Mapping sites of positive selection and amino acid diversification in the HIV genome
    • DE OLIVEIRA, T., M. SALEMI, M. GORDON, A. VANDAMME, E. J. VAN RENSBURG et al., 2004 Mapping sites of positive selection and amino acid diversification in the HIV genome. Genetics 167: 1047-1058.
    • (2004) Genetics , vol.167 , pp. 1047-1058
    • De Oliveira, T.1    Salemi, M.2    Gordon, M.3    Vandamme, A.4    Van Rensburg, E.J.5
  • 9
    • 0032954440 scopus 로고    scopus 로고
    • Structural and evolutionary inference from molecular variation in Neisseria porins
    • DERRICK, J. P., R. URWIN, J. SUKER, I. M. FEAVERS and M. C. J. MAIDEN, 1999 Structural and evolutionary inference from molecular variation in Neisseria porins. Infect. Immun. 67: 2406-2413.
    • (1999) Infect. Immun. , vol.67 , pp. 2406-2413
    • Derrick, J.P.1    Urwin, R.2    Suker, J.3    Feavers, I.M.4    Maiden, M.C.J.5
  • 11
    • 0035675042 scopus 로고    scopus 로고
    • Estimating recombination rates from population genetic data
    • FEARNHEAD, P., and P. DONNELLY, 2001 Estimating recombination rates from population genetic data. Genetics 159: 1299-1318.
    • (2001) Genetics , vol.159 , pp. 1299-1318
    • Fearnhead, P.1    Donnelly, P.2
  • 12
    • 0019797407 scopus 로고
    • Evolutionary trees from DNA sequences: A maximum likelihood approach
    • FELSENSTEIN, J., 1981 Evolutionary trees from DNA sequences: a maximum likelihood approach. J. Mol. Evol. 17: 368-376.
    • (1981) J. Mol. Evol. , vol.17 , pp. 368-376
    • Felsenstein, J.1
  • 13
    • 3242811414 scopus 로고    scopus 로고
    • Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates
    • FILIP, L. C., and N. I. MUNDY, 2004 Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates. Mol. Biol. Evol. 21: 1504-1511.
    • (2004) Mol. Biol. Evol. , vol.21 , pp. 1504-1511
    • Filip, L.C.1    Mundy, N.I.2
  • 14
    • 0035057075 scopus 로고    scopus 로고
    • Molecular evolution of transferrin: Evidence for positive selection in salmonids
    • FORD, M. J., 2001 Molecular evolution of transferrin: evidence for positive selection in salmonids. Mol. Biol. Evol. 18: 639-647.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 639-647
    • Ford, M.J.1
  • 15
    • 0028168856 scopus 로고
    • A codon-based model of nucleotide substitution for protein-coding DNA sequences
    • GOLDMAN, N., and Z. YANG, 1994 A codon-based model of nucleotide substitution for protein-coding DNA sequences. Mol. Biol. Evol. 11: 725-736.
    • (1994) Mol. Biol. Evol. , vol.11 , pp. 725-736
    • Goldman, N.1    Yang, Z.2
  • 16
    • 77956889087 scopus 로고
    • Reversible jump Markov chain Monte Carlo computation and Bayesian model determination
    • GREEN, P. J., 1995 Reversible jump Markov chain Monte Carlo computation and Bayesian model determination. Biometrika 82: 711-732.
    • (1995) Biometrika , vol.82 , pp. 711-732
    • Green, P.J.1
  • 17
    • 0000557367 scopus 로고    scopus 로고
    • An ancestral recombination graph
    • edited by P. DONNELLY and S. TAVARE. Springer-Verlag, Berlin/Heidelberg, Germany/New York
    • GRIFFITHS, R. C., and P. MARJORAM, 1997 An ancestral recombination graph, pp. 257-270 in Progress in Population Genetics and Human Evolution, edited by P. DONNELLY and S. TAVARE. Springer-Verlag, Berlin/Heidelberg, Germany/New York.
    • (1997) Progress in Population Genetics and Human Evolution , pp. 257-270
    • Griffiths, R.C.1    Marjoram, P.2
  • 19
    • 0020744702 scopus 로고
    • Properties of a neutral allele model with intragenic recombination
    • HUDSON, R. R., 1983 Properties of a neutral allele model with intragenic recombination. Theor. Popul. Biol. 23: 183-201.
    • (1983) Theor. Popul. Biol. , vol.23 , pp. 183-201
    • Hudson, R.R.1
  • 20
    • 0022211482 scopus 로고
    • Statistical properties of the number of recombination events in the history of a sample of DNA-sequences
    • HUDSON, R. R., and N. L. KAPLAN, 1985 Statistical properties of the number of recombination events in the history of a sample of DNA-sequences. Genetics 111: 147-164.
    • (1985) Genetics , vol.111 , pp. 147-164
    • Hudson, R.R.1    Kaplan, N.L.2
  • 21
    • 2942656772 scopus 로고    scopus 로고
    • Bayesian estimation of positively selected sites
    • HUELSENBECK, J. P., and K. A. DYER, 2004 Bayesian estimation of positively selected sites. J. Mol. Evol. 58: 661-672.
    • (2004) J. Mol. Evol. , vol.58 , pp. 661-672
    • Huelsenbeck, J.P.1    Dyer, K.A.2
  • 22
    • 0034462725 scopus 로고    scopus 로고
    • Carried meningococci in the Czech Republic: A diverse recombining population
    • JOLLEY, K. A., J. KALMUSOVA, E. J. FEIL, S. GUPTA, M. MUSILEK et al., 2000 Carried meningococci in the Czech Republic: a diverse recombining population. J. Clin. Microbiol. 38: 4492-4498.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 4492-4498
    • Jolley, K.A.1    Kalmusova, J.2    Feil, E.J.3    Gupta, S.4    Musilek, M.5
  • 23
    • 14544305228 scopus 로고    scopus 로고
    • The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis
    • JOLLEY, K. A., D. J. WILSON, P. KRIZ, G. MCVEAN and M. C. J. MAIDEN, 2005 The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis. Mol. Biol. Evol. 22: 562-569.
    • (2005) Mol. Biol. Evol. , vol.22 , pp. 562-569
    • Jolley, K.A.1    Wilson, D.J.2    Kriz, P.3    McVean, G.4    Maiden, M.C.J.5
  • 24
    • 0002556819 scopus 로고
    • On the genealogy of large populations
    • KINGMAN, J. F. C., 1982 On the genealogy of large populations. J. Appl. Probab. 19A: 27-43.
    • (1982) J. Appl. Probab. , vol.19 A , pp. 27-43
    • Kingman, J.F.C.1
  • 25
    • 17744396121 scopus 로고    scopus 로고
    • Not so different after all: A comparison of methods for detecting amino-acid sites under selection
    • KOSAKOVSKY POND, S. L., and S. D. FROST, 2005 Not so different after all: a comparison of methods for detecting amino-acid sites under selection. Mol. Biol. Evol. 22: 1208-1222.
    • (2005) Mol. Biol. Evol. , vol.22 , pp. 1208-1222
    • Kosakovsky Pond, S.L.1    Frost, S.D.2
  • 26
    • 0033756316 scopus 로고    scopus 로고
    • Maximum likelihood estimation of recombination rates from population data
    • KUHNER,M. K., J. YAMATO and J. FELSENSTEIN, 2000 Maximum likelihood estimation of recombination rates from population data. Genetics 156: 1393-1401.
    • (2000) Genetics , vol.156 , pp. 1393-1401
    • Kuhner, M.K.1    Yamato, J.2    Felsenstein, J.3
  • 27
    • 0347361674 scopus 로고    scopus 로고
    • Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data
    • LI, N., and M. STEPHENS, 2003 Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics 165: 2213-2233.
    • (2003) Genetics , vol.165 , pp. 2213-2233
    • Li, N.1    Stephens, M.2
  • 28
    • 0036470051 scopus 로고    scopus 로고
    • Protein explorer: Easy yet powerful macromolecular visualization
    • MARTZ, E., 2002 Protein explorer: easy yet powerful macromolecular visualization. Trends Biochem. Sci. 27: 107-109.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 107-109
    • Martz, E.1
  • 29
    • 17444412589 scopus 로고    scopus 로고
    • Detecting amino acid sites under positive selection and purifying selection
    • MASSINGHAM, T., and N. GOLDMAN, 2005 Detecting amino acid sites under positive selection and purifying selection. Genetics 169: 1753-1762.
    • (2005) Genetics , vol.169 , pp. 1753-1762
    • Massingham, T.1    Goldman, N.2
  • 30
    • 0036199914 scopus 로고    scopus 로고
    • A coalescent-based method for detecting and estimating recombination from gene sequences
    • MCVEAN, G., P. AWADALLA and P. FEARNHEAD, 2002 A coalescent-based method for detecting and estimating recombination from gene sequences. Genetics 160: 1231-1241.
    • (2002) Genetics , vol.160 , pp. 1231-1241
    • McVean, G.1    Awadalla, P.2    Fearnhead, P.3
  • 31
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • MCVEAN, G. A. T., S. R. MYERS, S. HUNT, P. DELOUKAS, D. R. BENTLEY et al., 2004 The fine-scale structure of recombination rate variation in the human genome. Science 304: 581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.T.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5
  • 32
    • 0042742904 scopus 로고
    • Posterior predictive P-values
    • MENG, X.-L., 1994 Posterior predictive P-values. Ann. Stat. 22: 1142-1160.
    • (1994) Ann. Stat. , vol.22 , pp. 1142-1160
    • Meng, X.-L.1
  • 33
    • 0034751729 scopus 로고    scopus 로고
    • The correlation between linkage disequilibrium and distance: Implications for recombination in hominid mitochondria
    • MEUNIER, J., and A. EYRE-WALKER, 2001 The correlation between linkage disequilibrium and distance: implications for recombination in hominid mitochondria. Mol. Biol. Evol. 18: 2132-2135.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 2132-2135
    • Meunier, J.1    Eyre-Walker, A.2
  • 34
    • 21444455535 scopus 로고    scopus 로고
    • Dual multiple change-point model leads to more accurate recombination detection
    • MININ, V. N., K. S. DORMAN, F. FANG and M. A. SUCHARD, 2005 Dual multiple change-point model leads to more accurate recombination detection. Bioinformatics 21: 3034-3042.
    • (2005) Bioinformatics , vol.21 , pp. 3034-3042
    • Minin, V.N.1    Dorman, K.S.2    Fang, F.3    Suchard, M.A.4
  • 35
    • 0036739297 scopus 로고    scopus 로고
    • Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thaliana
    • MONDRAGON-PALOMINO, M., B. C. MEYERS, R. W. MICHELMORE AND B. S. GAUT, 2002 Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thaliana. Genome Res. 12: 1305-1315.
    • (2002) Genome Res. , vol.12 , pp. 1305-1315
    • Mondragon-Palomino, M.1    Meyers, B.C.2    Michelmore, R.W.3    Gaut, B.S.4
  • 36
    • 3242789545 scopus 로고    scopus 로고
    • Differential selection of genes of cucumber mosaic virus subgroups
    • MOURY, B., 2004 Differential selection of genes of cucumber mosaic virus subgroups. Mol. Biol. Evol. 21: 1602-1611.
    • (2004) Mol. Biol. Evol. , vol.21 , pp. 1602-1611
    • Moury, B.1
  • 37
    • 0342614926 scopus 로고    scopus 로고
    • Codon usage tabulated from international DNA sequence databases: Status for the year 2000
    • NAKAMURA, Y., T. GOJOBORI and T. IKEMURA, 2000 Codon usage tabulated from international DNA sequence databases: status for the year 2000. Nucleic Acids Res. 28: 292.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 292
    • Nakamura, Y.1    Gojobori, T.2    Ikemura, T.3
  • 38
    • 0036366690 scopus 로고    scopus 로고
    • Detecting positively selected amino acid sites using posterior predictive p-values
    • edited by R. B. ALTMAN, A. K. DUNKER, L. HUNTER, K. LAUDERDALE AND T. E. KLEIN. World Scientific, Singapore
    • NIELSEN, R., and J. P. HUELSENBECK, 2002 Detecting positively selected amino acid sites using posterior predictive p-values, pp. 576-588 in Pacific Symposium on Biocomputing, Proceedings, edited by R. B. ALTMAN, A. K. DUNKER, L. HUNTER, K. LAUDERDALE AND T. E. KLEIN. World Scientific, Singapore.
    • (2002) Pacific Symposium on Biocomputing, Proceedings , pp. 576-588
    • Nielsen, R.1    Huelsenbeck, J.P.2
  • 39
    • 0031972161 scopus 로고    scopus 로고
    • Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene
    • NIELSEN, R., and Z. YANG, 1998 Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene. Genetics 148: 929-936.
    • (1998) Genetics , vol.148 , pp. 929-936
    • Nielsen, R.1    Yang, Z.2
  • 40
    • 0034732226 scopus 로고    scopus 로고
    • Complete DNA sequence of a serogroup a strain of Neisseria meningitidis Z2491
    • PARKHILL, J., M. ACHTMAN, K. D. JAMES, S. D. BENTLEY, C. CHURCHER et al., 2000 Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature 404: 502-506.
    • (2000) Nature , vol.404 , pp. 502-506
    • Parkhill, J.1    Achtman, M.2    James, K.D.3    Bentley, S.D.4    Churcher, C.5
  • 41
    • 0035095812 scopus 로고    scopus 로고
    • The interaction of protein structure, selection, and recombination on the evolution of the type-1 fimbrial major subunit (fimA) from Escherichia coli
    • PEEK, A. S., V. SOUZA, L. E. EGUIARTE and B. S. GAUT, 2001 The interaction of protein structure, selection, and recombination on the evolution of the type-1 fimbrial major subunit (fimA) from Escherichia coli. J. Mol. Evol. 52: 193-204.
    • (2001) J. Mol. Evol. , vol.52 , pp. 193-204
    • Peek, A.S.1    Souza, V.2    Eguiarte, L.E.3    Gaut, B.S.4
  • 42
    • 0000439370 scopus 로고
    • Bayesianly justifiable and relevant frequency calculations for the applied statistician
    • RUBIN, D. B., 1984 Bayesianly justifiable and relevant frequency calculations for the applied statistician. Ann. Stat. 12: 1151-1172.
    • (1984) Ann. Stat. , vol.12 , pp. 1151-1172
    • Rubin, D.B.1
  • 43
    • 0033793521 scopus 로고    scopus 로고
    • Consequences of recombination on traditional phylogenetic analysis
    • SCHIERUP, M. H., and J. HEIN, 2000 Consequences of recombination on traditional phylogenetic analysis. Genetics 156: 879-891.
    • (2000) Genetics , vol.156 , pp. 879-891
    • Schierup, M.H.1    Hein, J.2
  • 44
    • 0037986694 scopus 로고    scopus 로고
    • Potential impact of recombination on sitewise approaches for detecting positive natural selection
    • SHRINER, D., D. C. NICKLE, M. A. JENSEN and J. I. MULLINS, 2003 Potential impact of recombination on sitewise approaches for detecting positive natural selection. Genet. Res. 81: 115-121.
    • (2003) Genet. Res. , vol.81 , pp. 115-121
    • Shriner, D.1    Nickle, D.C.2    Jensen, M.A.3    Mullins, J.I.4
  • 45
    • 0028906959 scopus 로고
    • Sequence evolution of the porB gene of Neisseria gonorrhoeae and Neisseria meningitidis - Evidence of positive Darwinian selection
    • SMITH, N. H., J. M. SMITH and B. G. SPRATT, 1995 Sequence evolution of the porB gene of Neisseria gonorrhoeae and Neisseria meningitidis - evidence of positive Darwinian selection. Mol. Biol. Evol. 12: 363-370.
    • (1995) Mol. Biol. Evol. , vol.12 , pp. 363-370
    • Smith, N.H.1    Smith, J.M.2    Spratt, B.G.3
  • 46
    • 0344441428 scopus 로고    scopus 로고
    • Estimating recombination rates from population-genetic data
    • STUMPF, M. P. H., and G. A. T. MCVEAN, 2003 Estimating recombination rates from population-genetic data. Nat. Rev. Genet. 4: 959-968.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 959-968
    • Stumpf, M.P.H.1    McVean, G.A.T.2
  • 47
    • 0036803331 scopus 로고    scopus 로고
    • Oh brother, where art thou? A Bayes factor test for recombination with uncertain heritage
    • SUCHARD, M. A., R. E. WEISS, K. S. DORMAN and J. S. SINSHEIMER, 2002 Oh brother, where art thou? A Bayes factor test for recombination with uncertain heritage. Syst. Biol. 51: 715-728.
    • (2002) Syst. Biol. , vol.51 , pp. 715-728
    • Suchard, M.A.1    Weiss, R.E.2    Dorman, K.S.3    Sinsheimer, J.S.4
  • 48
    • 0037230001 scopus 로고    scopus 로고
    • Pervasive adaptive evolution in mammalian fertilization proteins
    • SWANSON, W. J., R. NIELSEN and Q. YANG, 2003 Pervasive adaptive evolution in mammalian fertilization proteins. Mol. Biol. Evol. 20: 18-20.
    • (2003) Mol. Biol. Evol. , vol.20 , pp. 18-20
    • Swanson, W.J.1    Nielsen, R.2    Yang, Q.3
  • 49
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • TAJIMA, F., 1989 Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123: 585-595.
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 50
    • 0036297139 scopus 로고    scopus 로고
    • Phylogenetic evidence for adaptive evolution of dengue viruses in nature
    • TWIDDY, S. S., C. H. WOELK and E. C. HOLMES, 2002 Phylogenetic evidence for adaptive evolution of dengue viruses in nature. J. Gen. Virol. 83: 1679-1689.
    • (2002) J. Gen. Virol. , vol.83 , pp. 1679-1689
    • Twiddy, S.S.1    Woelk, C.H.2    Holmes, E.C.3
  • 51
    • 0036791109 scopus 로고    scopus 로고
    • Phylogenetic evidence for frequent positive selection and recombination in the meningococcal surface antigen PorB
    • URWIN, R., E. C. HOLMES,A. J. FOX, J. P. DERRICK and M. C. J. MAIDEN, 2002 Phylogenetic evidence for frequent positive selection and recombination in the meningococcal surface antigen PorB. Mol. Biol. Evol. 19: 1686-1694.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1686-1694
    • Urwin, R.1    Holmes, E.C.2    Fox, A.J.3    Derrick, J.P.4    Maiden, M.C.J.5
  • 52
    • 0034758281 scopus 로고    scopus 로고
    • Gene genealogies in a metapopulation
    • WAKELEY, J., and N. ALIACAR, 2001 Gene genealogies in a metapopulation. Genetics 159: 893-905.
    • (2001) Genetics , vol.159 , pp. 893-905
    • Wakeley, J.1    Aliacar, N.2
  • 54
    • 20144387806 scopus 로고    scopus 로고
    • Comparison of fine-scale recombination rates in humans and chimpanzees
    • WINCKLER, W., S. R. MYERS, D. J. RICHTER, R. C. ONOFRIO, G. J. MCDONALD et al., 2005 Comparison of fine-scale recombination rates in humans and chimpanzees. Science 308: 107-111.
    • (2005) Science , vol.308 , pp. 107-111
    • Winckler, W.1    Myers, S.R.2    Richter, D.J.3    Onofrio, R.C.4    Mcdonald, G.J.5
  • 55
    • 8544225780 scopus 로고    scopus 로고
    • Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sites
    • WONG, W. S., Z. YANG, N. GOLDMAN and R. NIELSEN, 2004 Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sites. Genetics 168: 1041-1051.
    • (2004) Genetics , vol.168 , pp. 1041-1051
    • Wong, W.S.1    Yang, Z.2    Goldman, N.3    Nielsen, R.4
  • 56
    • 0030683599 scopus 로고    scopus 로고
    • PAML: A program package for phylogenetic analysis by maximum likelihood
    • YANG, Z., 1997 PAML: a program package for phylogenetic analysis by maximum likelihood. Comput. Appl. Biosci. 13: 555-556.
    • (1997) Comput. Appl. Biosci. , vol.13 , pp. 555-556
    • Yang, Z.1
  • 57
    • 0036134765 scopus 로고    scopus 로고
    • Codon-substitution models to detect adaptive evolution that account for heterogeneous selective pressures among site classes
    • YANG, Z., ANDW. J. SWANSON, 2002 Codon-substitution models to detect adaptive evolution that account for heterogeneous selective pressures among site classes. Mol. Biol. Evol. 19: 49-57.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 49-57
    • Yang, Z.1    Swanson, W.J.2
  • 58
    • 0034097381 scopus 로고    scopus 로고
    • Codon-substitution models for heterogeneous selection pressure at amino acid sites
    • YANG, Z., R. NIELSEN, N. GOLDMAN and A. M. PEDERSEN, 2000 Codon-substitution models for heterogeneous selection pressure at amino acid sites. Genetics 155: 431-449.
    • (2000) Genetics , vol.155 , pp. 431-449
    • Yang, Z.1    Nielsen, R.2    Goldman, N.3    Pedersen, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.