-
1
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos G.D., Davis S., Gale N.W., Rudge J.S., Wiegand S.J., Holash J. Vascular-specific growth factors and blood vessel formation. Nature. 407:2000;242-248
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
2
-
-
0031278261
-
Profound effects on vascular development caused by perturbations during organogenesis
-
Auerbach R., Auerbach W. Profound effects on vascular development caused by perturbations during organogenesis. Am. J. Pathol. 151:1997;1183-1186
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1183-1186
-
-
Auerbach, R.1
Auerbach, W.2
-
5
-
-
0032504752
-
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
-
Asahara T., Chen D., Takahashi T., Fujikawa K., Kearney M., Magner M., Yancopoulos G.D., Isner J.M. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ. Res. 83:1998;233-240
-
(1998)
Circ. Res.
, vol.83
, pp. 233-240
-
-
Asahara, T.1
Chen, D.2
Takahashi, T.3
Fujikawa, K.4
Kearney, M.5
Magner, M.6
Yancopoulos, G.D.7
Isner, J.M.8
-
6
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
-
Davis S., Aldrich T.H., Jones P.F., Acheson A., Compton D.L., Jain V., Ryan T.E., Bruno J., Radziejewski C., Maisonpierre P.C., Yancopoulos G.D. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell. 87:1996;1161-1169
-
(1996)
Cell
, vol.87
, pp. 1161-1169
-
-
Davis, S.1
Aldrich, T.H.2
Jones, P.F.3
Acheson, A.4
Compton, D.L.5
Jain, V.6
Ryan, T.E.7
Bruno, J.8
Radziejewski, C.9
Maisonpierre, P.C.10
Yancopoulos, G.D.11
-
7
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri C., Jones P.F., Patan S., Bartunkova S., Maisonpierre P.C., Davis S., Sato T.N., Yancopoulos G.D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 87:1996;1171-1180
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
Sato, T.N.7
Yancopoulos, G.D.8
-
8
-
-
0009587472
-
Angiopoietin-1 inhibits irradiation- and mannitol-induced apoptosis in endothelial cells
-
Kwak H.J., Lee S.J., Lee Y.H., Ryu C.H., Koh K.N., Choi H.Y., Koh G.Y. Angiopoietin-1 inhibits irradiation- and mannitol-induced apoptosis in endothelial cells. Circulation. 101:2000;2317-2324
-
(2000)
Circulation
, vol.101
, pp. 2317-2324
-
-
Kwak, H.J.1
Lee, S.J.2
Lee, Y.H.3
Ryu, C.H.4
Koh, K.N.5
Choi, H.Y.6
Koh, G.Y.7
-
9
-
-
0033573099
-
Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells
-
Fujikawa K., de Aos Scherpenseel I., Jain S.K., Presman E., Christensen R.A., Varticovski L. Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells. Exp. Cell Res. 253:1999;663-672
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 663-672
-
-
Fujikawa, K.1
De Aos Scherpenseel, I.2
Jain, S.K.3
Presman, E.4
Christensen, R.A.5
Varticovski, L.6
-
10
-
-
0034737422
-
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
-
Papapetropoulos A., Fulton D., Mahboubi K., Kalb R.G., O'Connor D.S., Li F., Altieri D.C., Sessa W.C. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J. Biol. Chem. 275:2000;9102-9105
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9102-9105
-
-
Papapetropoulos, A.1
Fulton, D.2
Mahboubi, K.3
Kalb, R.G.4
O'Connor, D.S.5
Li, F.6
Altieri, D.C.7
Sessa, W.C.8
-
11
-
-
0034724736
-
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt
-
Morales-Ruiz M., Fulton D., Sowa G., Languino L.R., Fujio Y., Walsh K., Sessa W.C. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ. Res. 86:2000;892-896
-
(2000)
Circ. Res.
, vol.86
, pp. 892-896
-
-
Morales-Ruiz, M.1
Fulton, D.2
Sowa, G.3
Languino, L.R.4
Fujio, Y.5
Walsh, K.6
Sessa, W.C.7
-
12
-
-
0033826581
-
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
-
Kureishi Y., Luo Z., Shiojima I., Bialik A., Fulton D., Lefer D.J., Sessa W.C., Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat. Med. 6:2000;1004-1010
-
(2000)
Nat. Med.
, vol.6
, pp. 1004-1010
-
-
Kureishi, Y.1
Luo, Z.2
Shiojima, I.3
Bialik, A.4
Fulton, D.5
Lefer, D.J.6
Sessa, W.C.7
Walsh, K.8
-
13
-
-
0032560058
-
Angiopoietin-1 induces sprouting angiogenesis in vitro
-
Koblizek T.I., Weiss C., Yancopoulos G.D., Deutsch U., Risau W. Angiopoietin-1 induces sprouting angiogenesis in vitro. Curr. Biol. 8:1998;529-532
-
(1998)
Curr. Biol.
, vol.8
, pp. 529-532
-
-
Koblizek, T.I.1
Weiss, C.2
Yancopoulos, G.D.3
Deutsch, U.4
Risau, W.5
-
14
-
-
0342657703
-
Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion
-
Kim I., Kim H.G., Moon S.O., Chae S.W., So J.N., Koh K.N., Ahn B.C., Koh G.Y. Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion. Circ. Res. 86:2000;952-959
-
(2000)
Circ. Res.
, vol.86
, pp. 952-959
-
-
Kim, I.1
Kim, H.G.2
Moon, S.O.3
Chae, S.W.4
So, J.N.5
Koh, K.N.6
Ahn, B.C.7
Koh, G.Y.8
-
15
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
Shiojima I., Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res. 90:2002;1243-1250
-
(2002)
Circ. Res.
, vol.90
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
17
-
-
0033597752
-
Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Clambda do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription
-
Kotani K., Ogawa W., Hino Y., Kitamura T., Ueno H., Sano W., Sutherland C., Granner D.K., Kasuga M. Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Clambda do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription. J. Biol. Chem. 274:1999;21305-21312
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21305-21312
-
-
Kotani, K.1
Ogawa, W.2
Hino, Y.3
Kitamura, T.4
Ueno, H.5
Sano, W.6
Sutherland, C.7
Granner, D.K.8
Kasuga, M.9
-
18
-
-
13144254247
-
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
-
Lin P., Buxton J.A., Acheson A., Radziejewski C., Maisonpierre P.C., Yancopoulos G.D., Channon K.M., Hale L.P., Dewhirst M.W., George S.E., Peters K.G. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc. Natl. Acad. Sci. U. S. A. 95:1998;8829-8834
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8829-8834
-
-
Lin, P.1
Buxton, J.A.2
Acheson, A.3
Radziejewski, C.4
Maisonpierre, P.C.5
Yancopoulos, G.D.6
Channon, K.M.7
Hale, L.P.8
Dewhirst, M.W.9
George, S.E.10
Peters, K.G.11
-
19
-
-
0031965353
-
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
-
Lin P., Sankar S., Shan S., Dewhirst M.W., Polverini P.J., Quinn T.Q., Peters K.G. Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ. 9:1998;49-58
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 49-58
-
-
Lin, P.1
Sankar, S.2
Shan, S.3
Dewhirst, M.W.4
Polverini, P.J.5
Quinn, T.Q.6
Peters, K.G.7
-
20
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng L., Donnelly E., McMahon G., Lin P.C., Sierra-Rivera E., Oshinka H., Hallahan D.E. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res. 61:2001;2413-2419
-
(2001)
Cancer Res.
, vol.61
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
Lin, P.C.4
Sierra-Rivera, E.5
Oshinka, H.6
Hallahan, D.E.7
-
21
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
Gerber H.P., McMurtrey A., Kowalski J., Yan M., Keyt B.A., Dixit V., Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem. 273:1998;30336-30343
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
22
-
-
0030726988
-
Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth
-
Lin P., Polverini P., Dewhirst M., Shan S., Rao P.S., Peters K. Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. J. Clin. Invest. 100:1997;2072-2078
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2072-2078
-
-
Lin, P.1
Polverini, P.2
Dewhirst, M.3
Shan, S.4
Rao, P.S.5
Peters, K.6
-
23
-
-
0033522927
-
Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
-
Fujio Y., Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J. Biol. Chem. 274:1999;16349-16354
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16349-16354
-
-
Fujio, Y.1
Walsh, K.2
-
24
-
-
0034525423
-
Kinases: Positive and negative regulators of apoptosis
-
Franklin R.A., McCubrey J.A. Kinases: positive and negative regulators of apoptosis. Leukemia. 14:2000;2019-2034
-
(2000)
Leukemia
, vol.14
, pp. 2019-2034
-
-
Franklin, R.A.1
McCubrey, J.A.2
-
25
-
-
0033558798
-
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
-
Gupta K., Kshirsagar S., Li W., Gui L., Ramakrishnan S., Gupta P., Law P.Y., Hebbel R.P. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp. Cell Res. 247:1999;495-504
-
(1999)
Exp. Cell Res.
, vol.247
, pp. 495-504
-
-
Gupta, K.1
Kshirsagar, S.2
Li, W.3
Gui, L.4
Ramakrishnan, S.5
Gupta, P.6
Law, P.Y.7
Hebbel, R.P.8
-
26
-
-
0034699326
-
Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis
-
Baek J.H., Jang J.E., Kang C.M., Chung H.Y., Kim N.D., Kim K.W. Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis. Oncogene. 19:2000;4621-4631
-
(2000)
Oncogene
, vol.19
, pp. 4621-4631
-
-
Baek, J.H.1
Jang, J.E.2
Kang, C.M.3
Chung, H.Y.4
Kim, N.D.5
Kim, K.W.6
-
27
-
-
0033517840
-
Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells
-
Tran J., Rak J., Sheehan C., Saibil S.D., LaCasse E., Korneluk R.G., Kerbel R.S. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem. Biophys. Res. Commun. 264:1999;781-788
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 781-788
-
-
Tran, J.1
Rak, J.2
Sheehan, C.3
Saibil, S.D.4
Lacasse, E.5
Korneluk, R.G.6
Kerbel, R.S.7
-
28
-
-
0035049227
-
Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator-activated receptor-gamma
-
Inoue M., Itoh H., Tanaka T., Chun T.H., Doi K., Fukunaga Y., Sawada N., Yamshita J., Masatsugu K., Saito T., Sakaguchi S., Sone M., Yamahara K., Yurugi T., Nakao K. Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator-activated receptor-gamma. Arterioscler., Thromb., Vasc. Biol. 21:2001;560-566
-
(2001)
Arterioscler., Thromb., Vasc. Biol.
, vol.21
, pp. 560-566
-
-
Inoue, M.1
Itoh, H.2
Tanaka, T.3
Chun, T.H.4
Doi, K.5
Fukunaga, Y.6
Sawada, N.7
Yamshita, J.8
Masatsugu, K.9
Saito, T.10
Sakaguchi, S.11
Sone, M.12
Yamahara, K.13
Yurugi, T.14
Nakao, K.15
-
29
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
Pai R., Soreghan B., Szabo I.L., Pavelka M., Baatar D., Tarnawski A.S. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat. Med. 8:2002;289-293
-
(2002)
Nat. Med.
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
Pavelka, M.4
Baatar, D.5
Tarnawski, A.S.6
-
30
-
-
0033119572
-
Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase
-
Wang D., Huang H.J., Kazlauskas A., Cavenee W.K. Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res. 59:1999;1464-1472
-
(1999)
Cancer Res.
, vol.59
, pp. 1464-1472
-
-
Wang, D.1
Huang, H.J.2
Kazlauskas, A.3
Cavenee, W.K.4
-
31
-
-
0030735593
-
Detection of vascular endothelial growth factor (VEGF) protein in vascular and non-vascular cells of the normal and oxygen-injured rat retina
-
Robbins S.G., Conaway J.R., Ford B.L., Roberto K.A., Penn J.S. Detection of vascular endothelial growth factor (VEGF) protein in vascular and non-vascular cells of the normal and oxygen-injured rat retina. Growth Factors. 14:1997;229-241
-
(1997)
Growth Factors
, vol.14
, pp. 229-241
-
-
Robbins, S.G.1
Conaway, J.R.2
Ford, B.L.3
Roberto, K.A.4
Penn, J.S.5
-
32
-
-
0038237021
-
Nutritional regulation of white adipocyte vascular endothelial growth factor (VEGF)
-
Wang X., McCormick K., Mick G. Nutritional regulation of white adipocyte vascular endothelial growth factor (VEGF). Horm. Metab. Res. 35:2003;211-216
-
(2003)
Horm. Metab. Res.
, vol.35
, pp. 211-216
-
-
Wang, X.1
McCormick, K.2
Mick, G.3
-
33
-
-
1842478183
-
Hypoxic regulation of angiopoietin-2 expression in endothelial cells
-
Pichiule P., Chavez J.C., LaManna J.C. Hypoxic regulation of angiopoietin-2 expression in endothelial cells. J. Biol. Chem. 279:2003;12171-12180
-
(2003)
J. Biol. Chem.
, vol.279
, pp. 12171-12180
-
-
Pichiule, P.1
Chavez, J.C.2
Lamanna, J.C.3
-
34
-
-
0141760474
-
Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoietin-2 and epidermal production of vascular endothelial growth factor
-
Cerimele F., Brown L.F., Bravo F., Ihler G.M., Kouadio P., Arbiser J.L. Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoietin-2 and epidermal production of vascular endothelial growth factor. Am. J. Pathol. 163:2003;1321-1327
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 1321-1327
-
-
Cerimele, F.1
Brown, L.F.2
Bravo, F.3
Ihler, G.M.4
Kouadio, P.5
Arbiser, J.L.6
-
35
-
-
0141640863
-
Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors
-
Yamakawa M., Liu L.X., Date T., Belanger A.J., Vincent K.A., Akita G.Y., Kuriyama T., Cheng S.H., Gregory R.J., Jiang C. Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors. Circ. Res. 93:2003;664-673
-
(2003)
Circ. Res.
, vol.93
, pp. 664-673
-
-
Yamakawa, M.1
Liu, L.X.2
Date, T.3
Belanger, A.J.4
Vincent, K.A.5
Akita, G.Y.6
Kuriyama, T.7
Cheng, S.H.8
Gregory, R.J.9
Jiang, C.10
-
37
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre P.C., Suri C., Jones P.F., Bartunkova S., Wiegand S.J., Radziejewski C., Compton D., McClain J., Aldrich T.H., Papadopoulos N., Daly T.J., Davis S., Sato T.N., Yancopoulos G.D. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science. 277:1997;55-60
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
38
-
-
0036153335
-
Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn
-
Mochizuki Y., Nakamura T., Kanetake H., Kanda S. Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn. J. Cell Sci. 115:2002;175-183
-
(2002)
J. Cell Sci.
, vol.115
, pp. 175-183
-
-
Mochizuki, Y.1
Nakamura, T.2
Kanetake, H.3
Kanda, S.4
-
39
-
-
13044292625
-
Angiopoietins 3 and 4: Diverging gene counterparts in mice and humans
-
Valenzuela D.M., Griffiths J.A., Rojas J., Aldrich T.H., Jones P.F., Zhou H., McClain J., Copeland N.G., Gilbert D.J., Jenkins N.A., Huang T., Papadopoulos N., Maisonpierre P.C., Davis S., Yancopoulos G.D. Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc. Natl. Acad. Sci. U. S. A. 96:1999;1904-1909
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1904-1909
-
-
Valenzuela, D.M.1
Griffiths, J.A.2
Rojas, J.3
Aldrich, T.H.4
Jones, P.F.5
Zhou, H.6
McClain, J.7
Copeland, N.G.8
Gilbert, D.J.9
Jenkins, N.A.10
Huang, T.11
Papadopoulos, N.12
Maisonpierre, P.C.13
Davis, S.14
Yancopoulos, G.D.15
|