-
1
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman, A.R. (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell, 108, 171-182.
-
(2002)
Cell
, vol.108
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
2
-
-
0035801472
-
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
-
Tutt, A., Bertwistle, D., Valentine, J., Gabriel, A., Swift, S., Ross, G., Griffin, C., Thacker, J. and Ashworth, A. (2001) Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J., 20, 4704-4716.
-
(2001)
EMBO J.
, vol.20
, pp. 4704-4716
-
-
Tutt, A.1
Bertwistle, D.2
Valentine, J.3
Gabriel, A.4
Swift, S.5
Ross, G.6
Griffin, C.7
Thacker, J.8
Ashworth, A.9
-
3
-
-
0033533731
-
Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification
-
Tutt, A., Gabriel, A., Bertwistle, D., Connor, F., Paterson, H., Peacock, J., Ross, G. and Ashworth, A. (1999) Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr. Biol., 9, 1107-1110.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1107-1110
-
-
Tutt, A.1
Gabriel, A.2
Bertwistle, D.3
Connor, F.4
Paterson, H.5
Peacock, J.6
Ross, G.7
Ashworth, A.8
-
4
-
-
0033106326
-
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
Xu, X., Weaver, Z., Linke, S.P., Li, C., Gotay, J., Wang, X.W., Harris, C.C., Ried, T. and Deng, C.X. (1999) Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol. Cell, 3, 389-395.
-
(1999)
Mol. Cell
, vol.3
, pp. 389-395
-
-
Xu, X.1
Weaver, Z.2
Linke, S.P.3
Li, C.4
Gotay, J.5
Wang, X.W.6
Harris, C.C.7
Ried, T.8
Deng, C.X.9
-
5
-
-
0032573068
-
BRCA1 is associated with the centrosome during mitosis
-
Hsu, L.C. and White, R.L. (1998) BRCA1 is associated with the centrosome during mitosis. Proc. Natl Acad. Sci. USA, 95, 12983-12988.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 12983-12988
-
-
Hsu, L.C.1
White, R.L.2
-
6
-
-
0035502955
-
Identification of a gamma-tubulin-binding domain in BRCA1
-
Hsu, L.C., Doan, T.P. and White, R.L. (2001) Identification of a gamma-tubulin-binding domain in BRCA1. Cancer Res., 61, 7713-7718.
-
(2001)
Cancer Res.
, vol.61
, pp. 7713-7718
-
-
Hsu, L.C.1
Doan, T.P.2
White, R.L.3
-
7
-
-
7444222440
-
Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2
-
Daniels, M.J., Wang, Y., Lee, M. and Venkitaraman, A.R. (2004) Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2. Science, 306, 876-879.
-
(2004)
Science
, vol.306
, pp. 876-879
-
-
Daniels, M.J.1
Wang, Y.2
Lee, M.3
Venkitaraman, A.R.4
-
8
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce, A.J., Johnson, R.D., Thompson, L.H. and Jasin, M. (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13, 2633-2638.
-
(1999)
Genes Dev.
, vol.13
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
Jasin, M.4
-
9
-
-
0034306365
-
Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation
-
Griffin, C.S., Simpson, P.J., Wilson, C.R. and Thacker, J. (2000) Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat. Cell Biol., 2, 757-761.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 757-761
-
-
Griffin, C.S.1
Simpson, P.J.2
Wilson, C.R.3
Thacker, J.4
-
10
-
-
0242684551
-
A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility
-
Rafii, S., Lindblom, A., Reed, M., Meuth, M. and Cox, A. (2003) A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility. Hum. Mol. Genet., 12, 915-923.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 915-923
-
-
Rafii, S.1
Lindblom, A.2
Reed, M.3
Meuth, M.4
Cox, A.5
-
11
-
-
71749090715
-
Variants in DNA double-strand break repair genes and breast cancer susceptibility
-
Kuschel, B., Auranen, A., McBride, S., Novik, K.L., Antoniou, A., Lipscombe, J.M., Day, N.E., Easton, D.F., Ponder, B.A., Pharoah, P.D. et al. (2002) Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum. Mol. Genet., 11, 1399-1407.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1399-1407
-
-
Kuschel, B.1
Auranen, A.2
McBride, S.3
Novik, K.L.4
Antoniou, A.5
Lipscombe, J.M.6
Day, N.E.7
Easton, D.F.8
Ponder, B.A.9
Pharoah, P.D.10
-
12
-
-
4344620034
-
XRCC3 polymorphisms and risk of lung cancer
-
Jacobsen, N.R., Raaschou-Nielsen, O., Nexo, B., Wallin, H., Overvad, K., Tjonneland, A. and Vogel, U. (2004) XRCC3 polymorphisms and risk of lung cancer. Cancer Lett., 213, 67-72.
-
(2004)
Cancer Lett.
, vol.213
, pp. 67-72
-
-
Jacobsen, N.R.1
Raaschou-Nielsen, O.2
Nexo, B.3
Wallin, H.4
Overvad, K.5
Tjonneland, A.6
Vogel, U.7
-
13
-
-
1942502414
-
Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia
-
Seedhouse, C., Faulkner, R., Ashraf, N., Das-Gupta, E. and Russell, N. (2004) Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia. Clin. Cancer Res., 10, 2675-2680.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2675-2680
-
-
Seedhouse, C.1
Faulkner, R.2
Ashraf, N.3
Das-Gupta, E.4
Russell, N.5
-
14
-
-
7244258782
-
DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract
-
Benhamou, S., Tuimala, J., Bouchardy, C., Dayer, P., Sarasin, A. and Hirvonen, A. (2004) DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int. J. Cancer, 112, 901-904.
-
(2004)
Int. J. Cancer
, vol.112
, pp. 901-904
-
-
Benhamou, S.1
Tuimala, J.2
Bouchardy, C.3
Dayer, P.4
Sarasin, A.5
Hirvonen, A.6
-
15
-
-
0037782041
-
No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer
-
Jacobsen, N.R., Nexo, B.A., Olsen, A., Overvad, K., Wallin, H., Tjonneland, A. and Vogel, U. (2003) No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer. Cancer Epidemiol. Biomarkers Prev., 12, 584-585.
-
(2003)
Cancer Epidemiol. Biomarkers Prev.
, vol.12
, pp. 584-585
-
-
Jacobsen, N.R.1
Nexo, B.A.2
Olsen, A.3
Overvad, K.4
Wallin, H.5
Tjonneland, A.6
Vogel, U.7
-
16
-
-
2942519280
-
Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry
-
Figueiredo, J.C., Knight, J.A., Briollais, L., Andrulis, I.L. and Ozcelik, H. (2004) Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry. Cancer Epidemiol. Biomarkers Prev., 13, 583-591.
-
(2004)
Cancer Epidemiol. Biomarkers Prev.
, vol.13
, pp. 583-591
-
-
Figueiredo, J.C.1
Knight, J.A.2
Briollais, L.3
Andrulis, I.L.4
Ozcelik, H.5
-
17
-
-
13944268723
-
The RAD51 gene family, genetic instability and cancer
-
Thacker, J. (2005) The RAD51 gene family, genetic instability and cancer. Cancer Lett., 219, 125-135.
-
(2005)
Cancer Lett.
, vol.219
, pp. 125-135
-
-
Thacker, J.1
-
18
-
-
0037071901
-
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks
-
Araujo, F.D., Pierce, A.J., Stark, J.M. and Jasin, M. (2002) Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene, 21, 4176-4180.
-
(2002)
Oncogene
, vol.21
, pp. 4176-4180
-
-
Araujo, F.D.1
Pierce, A.J.2
Stark, J.M.3
Jasin, M.4
-
19
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer, C., Kinzler, K.W. and Vogelstein, B. (1998) Genetic instabilities in human cancers. Nature, 396, 643-649.
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
20
-
-
0029071063
-
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene
-
Tebbs, R.S., Zhao, Y., Tucker, J.D., Scheerer, J.B., Siciliano, M.J., Hwang, M., Liu, N., Legerski, R.J. and Thompson, L.H. (1995) Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc. Natl Acad. Sci. USA, 92, 6354-6358.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 6354-6358
-
-
Tebbs, R.S.1
Zhao, Y.2
Tucker, J.D.3
Scheerer, J.B.4
Siciliano, M.J.5
Hwang, M.6
Liu, N.7
Legerski, R.J.8
Thompson, L.H.9
-
21
-
-
0023905947
-
A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
-
Fuller, L.F. and Painter, R.B. (1988) A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat. Res., 193, 109-121.
-
(1988)
Mutat. Res.
, vol.193
, pp. 109-121
-
-
Fuller, L.F.1
Painter, R.B.2
-
22
-
-
0028174376
-
Video time-lapse study of mitosis in binucleate V79 cells: Chromosome segregation and cleavage
-
Schultz, N. and Onfelt, A. (1994) Video time-lapse study of mitosis in binucleate V79 cells: Chromosome segregation and cleavage. Mutagenesis, 9, 117-123.
-
(1994)
Mutagenesis
, vol.9
, pp. 117-123
-
-
Schultz, N.1
Onfelt, A.2
-
23
-
-
0037330699
-
Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3
-
Hinz, J.M., Helleday, T. and Meuth, M. (2003) Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3. Carcinogenesis, 24, 249-253.
-
(2003)
Carcinogenesis
, vol.24
, pp. 249-253
-
-
Hinz, J.M.1
Helleday, T.2
Meuth, M.3
-
24
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
Martin, S.J., Reutelingsperger, C.P., McGahon, A.J., Rader, J.A., van Schie, R.C., LaFace, D.M. and Green, D.R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med., 182, 1545-1556.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1545-1556
-
-
Martin, S.J.1
Reutelingsperger, C.P.2
McGahon, A.J.3
Rader, J.A.4
van Schie, R.C.5
LaFace, D.M.6
Green, D.R.7
-
25
-
-
2542464251
-
XRCC3 ATPase activity is required for normal XRCC3-Rad51C complex dynamics and homologous recombination
-
Yamada, N.A., Hinz, J.M., Kopf, V.L., Segalle, K.D. and Thompson, L.H. (2004) XRCC3 ATPase activity is required for normal XRCC3-Rad51C complex dynamics and homologous recombination. J. Biol. Chem., 279, 23250-23254.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23250-23254
-
-
Yamada, N.A.1
Hinz, J.M.2
Kopf, V.L.3
Segalle, K.D.4
Thompson, L.H.5
-
26
-
-
6344285329
-
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
-
Dodson, H., Bourke, E., Jeffers, L.J., Vagnarelli, P., Sonoda, E., Takeda, S., Earnshaw, W.C., Merdes, A. and Morrison, C. (2004) Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J., 23, 3864-3873.
-
(2004)
EMBO J.
, vol.23
, pp. 3864-3873
-
-
Dodson, H.1
Bourke, E.2
Jeffers, L.J.3
Vagnarelli, P.4
Sonoda, E.5
Takeda, S.6
Earnshaw, W.C.7
Merdes, A.8
Morrison, C.9
-
27
-
-
1442289296
-
XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells
-
Yoshihara, T., Ishida, M., Kinomura, A., Katsura, M., Tsuruga, T., Tashiro, S., Asahara, T. and Miyagawa, K. (2004) XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells. EMBO J., 23, 670-680.
-
(2004)
EMBO J.
, vol.23
, pp. 670-680
-
-
Yoshihara, T.1
Ishida, M.2
Kinomura, A.3
Katsura, M.4
Tsuruga, T.5
Tashiro, S.6
Asahara, T.7
Miyagawa, K.8
-
28
-
-
0012776441
-
Centrosomes split in the presence of impaired DNA integrity during mitosis
-
Hut, H.M., Lemstra, W., Blaauw, E.H., Van Cappellen, G.W., Kampinga, H.H. and Sibon, O.C. (2003) Centrosomes split in the presence of impaired DNA integrity during mitosis. Mol. Biol. Cell, 14, 1993-2004.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1993-2004
-
-
Hut, H.M.1
Lemstra, W.2
Blaauw, E.H.3
Van Cappellen, G.W.4
Kampinga, H.H.5
Sibon, O.C.6
-
29
-
-
0037134898
-
The centrosome cycle
-
Meraldi, P. and Nigg, E.A. (2002) The centrosome cycle. FEBS Lett., 521, 9-13.
-
(2002)
FEBS Lett.
, vol.521
, pp. 9-13
-
-
Meraldi, P.1
Nigg, E.A.2
-
30
-
-
4644281946
-
Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
-
Vogel, C., Kienitz, A., Hofmann, I., Muller, R. and Bastians, H. (2004) Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene, 23, 6845-6853.
-
(2004)
Oncogene
, vol.23
, pp. 6845-6853
-
-
Vogel, C.1
Kienitz, A.2
Hofmann, I.3
Muller, R.4
Bastians, H.5
-
31
-
-
0036711812
-
Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines
-
Mohindra, A., Hays, L.E., Phillips, E.N., Preston, B.D., Helleday, T. and Meuth, M. (2002) Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines. Hum. Mol. Genet., 11, 2189-2200.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2189-2200
-
-
Mohindra, A.1
Hays, L.E.2
Phillips, E.N.3
Preston, B.D.4
Helleday, T.5
Meuth, M.6
-
32
-
-
18344395671
-
Human MRE11 is inactivated in mismatch repair-deficient cancers
-
Giannini, G., Ristori, E., Cerignoli, F., Rinaldi, C., Zani, M., Viel, A., Ottini, L., Crescenzi, M., Martinotti, S., Bignami, M. et al. (2002) Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep., 3, 248-254.
-
(2002)
EMBO Rep.
, vol.3
, pp. 248-254
-
-
Giannini, G.1
Ristori, E.2
Cerignoli, F.3
Rinaldi, C.4
Zani, M.5
Viel, A.6
Ottini, L.7
Crescenzi, M.8
Martinotti, S.9
Bignami, M.10
-
33
-
-
0036809071
-
Increased recombination intermediates and homologous integration hot spots at DNA replication origins
-
Segurado, M., Gomez, M. and Antequera, F. (2002) Increased recombination intermediates and homologous integration hot spots at DNA replication origins. Mol. Cell, 10, 907-916.
-
(2002)
Mol. Cell
, vol.10
, pp. 907-916
-
-
Segurado, M.1
Gomez, M.2
Antequera, F.3
-
34
-
-
0030924656
-
Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
-
Ludwig, T., Chapman, D.L., Papaioannou, V.E. and Efstratiadis, A. (1997) Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev., 11, 1226-1241.
-
(1997)
Genes Dev.
, vol.11
, pp. 1226-1241
-
-
Ludwig, T.1
Chapman, D.L.2
Papaioannou, V.E.3
Efstratiadis, A.4
-
35
-
-
0030659153
-
Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation
-
Connor, F., Bertwistle, D., Mee, P.J., Ross, G.M., Swift, S., Grigorieva, E., Tybulewicz, V.L. and Ashworth, A. (1997) Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation. Nat. Genet., 17, 423-430.
-
(1997)
Nat. Genet.
, vol.17
, pp. 423-430
-
-
Connor, F.1
Bertwistle, D.2
Mee, P.J.3
Ross, G.M.4
Swift, S.5
Grigorieva, E.6
Tybulewicz, V.L.7
Ashworth, A.8
-
36
-
-
0030932869
-
Cancer-susceptibility genes. Gatekeepers and caretakers
-
Kinzler, K.W. and Vogelstein, B. (1997) Cancer-susceptibility genes. Gatekeepers and caretakers. Nature, 386, 761-763.
-
(1997)
Nature
, vol.386
, pp. 761-763
-
-
Kinzler, K.W.1
Vogelstein, B.2
|