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Volumn 15, Issue 7, 2006, Pages 1217-1224

Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; GENE PRODUCT; METHIONINE; PROTEIN XRCC3; THREONINE; UNCLASSIFIED DRUG;

EID: 33645130127     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl037     Document Type: Article
Times cited : (35)

References (36)
  • 1
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman, A.R. (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell, 108, 171-182.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 2
    • 0035801472 scopus 로고    scopus 로고
    • Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
    • Tutt, A., Bertwistle, D., Valentine, J., Gabriel, A., Swift, S., Ross, G., Griffin, C., Thacker, J. and Ashworth, A. (2001) Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J., 20, 4704-4716.
    • (2001) EMBO J. , vol.20 , pp. 4704-4716
    • Tutt, A.1    Bertwistle, D.2    Valentine, J.3    Gabriel, A.4    Swift, S.5    Ross, G.6    Griffin, C.7    Thacker, J.8    Ashworth, A.9
  • 3
    • 0033533731 scopus 로고    scopus 로고
    • Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification
    • Tutt, A., Gabriel, A., Bertwistle, D., Connor, F., Paterson, H., Peacock, J., Ross, G. and Ashworth, A. (1999) Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr. Biol., 9, 1107-1110.
    • (1999) Curr. Biol. , vol.9 , pp. 1107-1110
    • Tutt, A.1    Gabriel, A.2    Bertwistle, D.3    Connor, F.4    Paterson, H.5    Peacock, J.6    Ross, G.7    Ashworth, A.8
  • 4
    • 0033106326 scopus 로고    scopus 로고
    • Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
    • Xu, X., Weaver, Z., Linke, S.P., Li, C., Gotay, J., Wang, X.W., Harris, C.C., Ried, T. and Deng, C.X. (1999) Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol. Cell, 3, 389-395.
    • (1999) Mol. Cell , vol.3 , pp. 389-395
    • Xu, X.1    Weaver, Z.2    Linke, S.P.3    Li, C.4    Gotay, J.5    Wang, X.W.6    Harris, C.C.7    Ried, T.8    Deng, C.X.9
  • 5
    • 0032573068 scopus 로고    scopus 로고
    • BRCA1 is associated with the centrosome during mitosis
    • Hsu, L.C. and White, R.L. (1998) BRCA1 is associated with the centrosome during mitosis. Proc. Natl Acad. Sci. USA, 95, 12983-12988.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 12983-12988
    • Hsu, L.C.1    White, R.L.2
  • 6
    • 0035502955 scopus 로고    scopus 로고
    • Identification of a gamma-tubulin-binding domain in BRCA1
    • Hsu, L.C., Doan, T.P. and White, R.L. (2001) Identification of a gamma-tubulin-binding domain in BRCA1. Cancer Res., 61, 7713-7718.
    • (2001) Cancer Res. , vol.61 , pp. 7713-7718
    • Hsu, L.C.1    Doan, T.P.2    White, R.L.3
  • 7
    • 7444222440 scopus 로고    scopus 로고
    • Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2
    • Daniels, M.J., Wang, Y., Lee, M. and Venkitaraman, A.R. (2004) Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2. Science, 306, 876-879.
    • (2004) Science , vol.306 , pp. 876-879
    • Daniels, M.J.1    Wang, Y.2    Lee, M.3    Venkitaraman, A.R.4
  • 8
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce, A.J., Johnson, R.D., Thompson, L.H. and Jasin, M. (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13, 2633-2638.
    • (1999) Genes Dev. , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 9
    • 0034306365 scopus 로고    scopus 로고
    • Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation
    • Griffin, C.S., Simpson, P.J., Wilson, C.R. and Thacker, J. (2000) Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat. Cell Biol., 2, 757-761.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 757-761
    • Griffin, C.S.1    Simpson, P.J.2    Wilson, C.R.3    Thacker, J.4
  • 10
    • 0242684551 scopus 로고    scopus 로고
    • A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility
    • Rafii, S., Lindblom, A., Reed, M., Meuth, M. and Cox, A. (2003) A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility. Hum. Mol. Genet., 12, 915-923.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 915-923
    • Rafii, S.1    Lindblom, A.2    Reed, M.3    Meuth, M.4    Cox, A.5
  • 13
    • 1942502414 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia
    • Seedhouse, C., Faulkner, R., Ashraf, N., Das-Gupta, E. and Russell, N. (2004) Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia. Clin. Cancer Res., 10, 2675-2680.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2675-2680
    • Seedhouse, C.1    Faulkner, R.2    Ashraf, N.3    Das-Gupta, E.4    Russell, N.5
  • 14
    • 7244258782 scopus 로고    scopus 로고
    • DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract
    • Benhamou, S., Tuimala, J., Bouchardy, C., Dayer, P., Sarasin, A. and Hirvonen, A. (2004) DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int. J. Cancer, 112, 901-904.
    • (2004) Int. J. Cancer , vol.112 , pp. 901-904
    • Benhamou, S.1    Tuimala, J.2    Bouchardy, C.3    Dayer, P.4    Sarasin, A.5    Hirvonen, A.6
  • 16
    • 2942519280 scopus 로고    scopus 로고
    • Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry
    • Figueiredo, J.C., Knight, J.A., Briollais, L., Andrulis, I.L. and Ozcelik, H. (2004) Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry. Cancer Epidemiol. Biomarkers Prev., 13, 583-591.
    • (2004) Cancer Epidemiol. Biomarkers Prev. , vol.13 , pp. 583-591
    • Figueiredo, J.C.1    Knight, J.A.2    Briollais, L.3    Andrulis, I.L.4    Ozcelik, H.5
  • 17
    • 13944268723 scopus 로고    scopus 로고
    • The RAD51 gene family, genetic instability and cancer
    • Thacker, J. (2005) The RAD51 gene family, genetic instability and cancer. Cancer Lett., 219, 125-135.
    • (2005) Cancer Lett. , vol.219 , pp. 125-135
    • Thacker, J.1
  • 18
    • 0037071901 scopus 로고    scopus 로고
    • Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks
    • Araujo, F.D., Pierce, A.J., Stark, J.M. and Jasin, M. (2002) Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene, 21, 4176-4180.
    • (2002) Oncogene , vol.21 , pp. 4176-4180
    • Araujo, F.D.1    Pierce, A.J.2    Stark, J.M.3    Jasin, M.4
  • 19
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer, C., Kinzler, K.W. and Vogelstein, B. (1998) Genetic instabilities in human cancers. Nature, 396, 643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 21
    • 0023905947 scopus 로고
    • A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
    • Fuller, L.F. and Painter, R.B. (1988) A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat. Res., 193, 109-121.
    • (1988) Mutat. Res. , vol.193 , pp. 109-121
    • Fuller, L.F.1    Painter, R.B.2
  • 22
    • 0028174376 scopus 로고
    • Video time-lapse study of mitosis in binucleate V79 cells: Chromosome segregation and cleavage
    • Schultz, N. and Onfelt, A. (1994) Video time-lapse study of mitosis in binucleate V79 cells: Chromosome segregation and cleavage. Mutagenesis, 9, 117-123.
    • (1994) Mutagenesis , vol.9 , pp. 117-123
    • Schultz, N.1    Onfelt, A.2
  • 23
    • 0037330699 scopus 로고    scopus 로고
    • Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3
    • Hinz, J.M., Helleday, T. and Meuth, M. (2003) Reduced apoptotic response to camptothecin in CHO cells deficient in XRCC3. Carcinogenesis, 24, 249-253.
    • (2003) Carcinogenesis , vol.24 , pp. 249-253
    • Hinz, J.M.1    Helleday, T.2    Meuth, M.3
  • 24
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S.J., Reutelingsperger, C.P., McGahon, A.J., Rader, J.A., van Schie, R.C., LaFace, D.M. and Green, D.R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med., 182, 1545-1556.
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 25
    • 2542464251 scopus 로고    scopus 로고
    • XRCC3 ATPase activity is required for normal XRCC3-Rad51C complex dynamics and homologous recombination
    • Yamada, N.A., Hinz, J.M., Kopf, V.L., Segalle, K.D. and Thompson, L.H. (2004) XRCC3 ATPase activity is required for normal XRCC3-Rad51C complex dynamics and homologous recombination. J. Biol. Chem., 279, 23250-23254.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23250-23254
    • Yamada, N.A.1    Hinz, J.M.2    Kopf, V.L.3    Segalle, K.D.4    Thompson, L.H.5
  • 27
  • 29
    • 0037134898 scopus 로고    scopus 로고
    • The centrosome cycle
    • Meraldi, P. and Nigg, E.A. (2002) The centrosome cycle. FEBS Lett., 521, 9-13.
    • (2002) FEBS Lett. , vol.521 , pp. 9-13
    • Meraldi, P.1    Nigg, E.A.2
  • 30
    • 4644281946 scopus 로고    scopus 로고
    • Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
    • Vogel, C., Kienitz, A., Hofmann, I., Muller, R. and Bastians, H. (2004) Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene, 23, 6845-6853.
    • (2004) Oncogene , vol.23 , pp. 6845-6853
    • Vogel, C.1    Kienitz, A.2    Hofmann, I.3    Muller, R.4    Bastians, H.5
  • 31
    • 0036711812 scopus 로고    scopus 로고
    • Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines
    • Mohindra, A., Hays, L.E., Phillips, E.N., Preston, B.D., Helleday, T. and Meuth, M. (2002) Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines. Hum. Mol. Genet., 11, 2189-2200.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2189-2200
    • Mohindra, A.1    Hays, L.E.2    Phillips, E.N.3    Preston, B.D.4    Helleday, T.5    Meuth, M.6
  • 33
    • 0036809071 scopus 로고    scopus 로고
    • Increased recombination intermediates and homologous integration hot spots at DNA replication origins
    • Segurado, M., Gomez, M. and Antequera, F. (2002) Increased recombination intermediates and homologous integration hot spots at DNA replication origins. Mol. Cell, 10, 907-916.
    • (2002) Mol. Cell , vol.10 , pp. 907-916
    • Segurado, M.1    Gomez, M.2    Antequera, F.3
  • 34
    • 0030924656 scopus 로고    scopus 로고
    • Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
    • Ludwig, T., Chapman, D.L., Papaioannou, V.E. and Efstratiadis, A. (1997) Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev., 11, 1226-1241.
    • (1997) Genes Dev. , vol.11 , pp. 1226-1241
    • Ludwig, T.1    Chapman, D.L.2    Papaioannou, V.E.3    Efstratiadis, A.4
  • 36
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler, K.W. and Vogelstein, B. (1997) Cancer-susceptibility genes. Gatekeepers and caretakers. Nature, 386, 761-763.
    • (1997) Nature , vol.386 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.