The allosteric properties of hemoglobin: Insights from natural and site directed mutants

Current Protein and Peptide Science

Volumn 7, Issue 1, 2006, Pages 17-45

  Bellelli, Andrea ^a   Brunori, Maurizio ^a   Miele, Adriana Erica ^a   Panetta, Gianna ^a   Vallone, Beatrice ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Allosteric core; Cooperativity; Human hemoglobin; Naturally occurring mutants; Site directed mutants

Indexed keywords

GLUTAMIC ACID; HEME; HEMOGLOBIN; HEMOGLOBIN A; MYOGLOBIN; NITRIC OXIDE; OXYGEN; POLYPEPTIDE; LIGAND;

ALLOSTERISM; ALPHA CHAIN; AMINO ACID SEQUENCE; AUTOOXIDATION; BETA CHAIN; BIOCHEMISTRY; BIOREACTOR; CARBOXY TERMINAL SEQUENCE; CHIMERA; FLUID RESUSCITATION; HEMOGLOBINOPATHY; HUMAN; LIGAND BINDING; MACROMOLECULE; MOLECULAR MECHANICS; NONHUMAN; OXYGEN AFFINITY; POINT MUTATION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; PROTEIN CONFORMATION; PROTEIN QUATERNARY STRUCTURE;

ALLOSTERIC REGULATION; HEMOGLOBINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY;

EID: 33645127489     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920306775474121     Document Type: Review

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