Crystallographic, molecular modeling, and biophysical characterization of the valineβ67 (E11) → threonine variant of hemoglobin

Biochemistry

Volumn 35, Issue 6, 1996, Pages 1935-1945

  Pechik, Igor ^a,b,f   Ji, Xinhua ^a   Fidelis, Krzysztof ^a,c   Karavitis, Michael ^d   Moult, John ^a   Brinigar, William S ^e   Fronticelli, Clara ^d   Gilliland, Gary L ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^c LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e Temple University   (United States)

^f Temple University ^*

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; DEOXYHEMOGLOBIN; HEME; HEMIN; HEMOGLOBIN VARIANT; MYOGLOBIN; NITRIC OXIDE; THREONINE; VALINE; WATER;

ARTICLE; AUTOOXIDATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HYDROGEN BOND; INFRARED SPECTROSCOPY; MOLECULAR MODEL; OXYGEN AFFINITY; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BIOPHYSICS; CARBOXYHEMOGLOBIN; CRYSTALLOGRAPHY, X-RAY; ELECTROCHEMISTRY; HEME; HEMOGLOBIN A; HEMOGLOBINS; HUMANS; MODELS, MOLECULAR; NITRIC OXIDE; OXIDATION-REDUCTION; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; THREONINE; VARIATION (GENETICS);

OXY; SUIDAE;

EID: 0030068978     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9519967     Document Type: Article

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