Waterproofing the heme pocket: Role of proximal amino acid side chains in preventing hemin loss from myoglobin

Journal of Biological Chemistry

Volumn 276, Issue 12, 2001, Pages 9093-9100

  Liong, Elaine C ^a   Dou, Yi ^d   Scott, Emily E ^b   Olson, John S ^d   Phillips Jr , George N ^c  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ELECTROSTATICS; HYDROPHOBICITY; MUTAGENESIS; SOLVENTS; X RAY CRYSTALLOGRAPHY;

PORPHYRIN RING; PROSTHETIC GROUP;

HEMOGLOBIN;

AMINO ACID; GLOBIN; HEME; HEMIN; HEMOGLOBIN; HISTIDINE; ISOLEUCINE; LEUCINE; MUTANT PROTEIN; MYOGLOBIN; PORPHYRIN; SOLVENT; WATER; OXYGEN; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHEMICAL BOND; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STEREOCHEMISTRY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION; WHALE;

AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HEME; MODELS, MOLECULAR; MYOGLOBIN; OXYGEN; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; WHALES;

EID: 0035937761     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008593200     Document Type: Article

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