A biophysical investigation of recombinant hemoglobins with aromatic B10 mutations in the distal heme pockets

Biochemistry

Volumn 44, Issue 19, 2005, Pages 7207-7217

  Wiltrout, Mary Ellen ^a   Giovannelli, Janel L ^a   Simplaceanu, Virgil ^a   Lukin, Jonathan A ^a,b   Ho, Nancy T ^a   Ho, Chien ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; MOLECULAR DYNAMICS; MUTAGENS; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PROTONS; RATE CONSTANTS; SPECTROPHOTOMETRY;

AROMATIC B10 MUTATIONS; BIMOLECULAR RATE CONSTANTS; FUNCTIONAL PROPERTIES; HEMOGLOBINS;

AMINO ACIDS;

AMINO ACID; HEME; NITRIC OXIDE; RECOMBINANT HEMOGLOBIN;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; AUTOOXIDATION; BETA CHAIN; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; MUTATION; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROPHOTOMETRY;

ADULT; AMINO ACID SUBSTITUTION; AZIDES; HEME; HEMOGLOBIN A; HEMOGLOBINS; HUMANS; LEUCINE; NITRIC OXIDE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; OXYGEN; PHENYLALANINE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; THERMODYNAMICS; TRYPTOPHAN;

ESCHERICHIA COLI;

EID: 18544388369     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048289a     Document Type: Article

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