The artificial α1β1-contact mutant hemoglobin, Hb Phe-35β, shows only small functional abnormalities

FEBS Letters

Volumn 441, Issue 1, 1998, Pages 93-96

  Nakatsukasa, Takashi ^a   Nomura, Noriko ^a   Miyazaki, Gentaro ^a   Imai, Kiyohiro ^a   Wada, Yoshinao ^b   Ishimori, Koichiro ^c   Morishima, Isao ^c   Morimoto, Hideki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Hemoglobin; Mutagenesis; Nuclear magnetic resonance; Oxygen affinity

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A; GLOBIN; HEMOGLOBIN; OXYHEMOGLOBIN; PHENYLALANINE; RECOMBINANT PROTEIN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; HUMAN; HYDROGEN BOND; MUTAGENESIS; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTEIN STRUCTURE, FUNCTION AND VARIABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; TITRIMETRY; BINDING SITE; CHEMISTRY; KINETICS; MACROMOLECULE; METABOLISM; NUCLEAR MAGNETIC RESONANCE; POINT MUTATION; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; BINDING SITES; GLOBINS; HEMOGLOBINS; HUMANS; HYDROGEN BONDING; KINETICS; MACROMOLECULAR SUBSTANCES; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXYHEMOGLOBINS; PHENYLALANINE; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; TYROSINE;

EID: 0032217065     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01535-X     Document Type: Article

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