-
1
-
-
0036727746
-
Genetics, cytokines and human infectious disease: Lessons from weakly pathogenic mycobacteria and salmonellae
-
Ottenhoff, T. H., Verreck, F. A., Lichtenauer-Kaligis, E. G., Hoeve, M. A., Sanal, O. and Van Diesel, J. T., Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae. Nat. Genet. 2002. 32: 97-105.
-
(2002)
Nat. Genet.
, vol.32
, pp. 97-105
-
-
Ottenhoff, T.H.1
Verreck, F.A.2
Lichtenauer-Kaligis, E.G.3
Hoeve, M.A.4
Sanal, O.5
Van Diesel, J.T.6
-
2
-
-
0037261363
-
Severe Mycobacterium bovis BCG infections in a large series of novel IL-12 receptor beta 1 deficient patients and evidence for the existence of partial IL-12 receptor beta 1 deficiency
-
Lichtenauer-Kaligis, E. G., de Boer, T., Verreck, F. A., van Voorden, J., Hoeve, M. A., van Diesel, J., Sanal, O. and Ottenhoff, T. H., Severe Mycobacterium bovis BCG infections in a large series of novel IL-12 receptor beta 1 deficient patients and evidence for the existence of partial IL-12 receptor beta 1 deficiency. Eur. J. Immunol. 2003. 33: 59-69.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 59-69
-
-
Lichtenauer-Kaligis, E.G.1
de Boer, T.2
Verreck, F.A.3
van Voorden, J.4
Hoeve, M.A.5
van Diesel, J.6
Sanal, O.7
Ottenhoff, T.H.8
-
3
-
-
0037450808
-
Low penetrance, broad resistance and a favorable outcome of interleukin 12 receptor β1 deficiency: Medical and immunological implications
-
Fieschi, C., Dupuis, S., Catherinot, E., Feinberg, J., Bustsmante, J., Breiman, A., Altare, F., Baretto, R, Le Deist, F., Kayal, S. et al., Low penetrance, broad resistance and a favorable outcome of interleukin 12 receptor β1 deficiency: medical and immunological implications. J. Exp. Med. 2003. 197: 527-535.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 527-535
-
-
Fieschi, C.1
Dupuis, S.2
Catherinot, E.3
Feinberg, J.4
Bustsmante, J.5
Breiman, A.6
Altare, F.7
Baretto, R.8
Le Deist, F.9
Kayal, S.10
-
4
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, F. et al., Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000. 13: 715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, F.10
-
5
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
-
Parham, C., Chirica, M., Timans, J., Vaisberg, E., Travis, M., Cheung, J., Pflanz, S., Zhang, R., Singh, K. P., Vega, F. et al., A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J. Immunol. 2002. 168: 5699-5708.
-
(2002)
J. Immunol.
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
-
6
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cue, D. J., Sherlock, J., Chen, Y., Murphy, C. A., Joyce, B., Seymour, B., Lucian, L., To, W., Kwan, S., Churakova, T. et al., Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003. 421: 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cue, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
7
-
-
0034698827
-
Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rβ1): Evidence for an IL- 12Rβ1-independent pathway of IL-12 responsiveness in human T cells
-
Verhagen, C. E., de Boer, T., Smits, H. H., Verreck, F. A., Wierange, E. A., Kurimoto, M., Lammas, D. A., Kumararatne, D. S., Sanal, O., Kroon, F. P. et al., Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rβ1): evidence for an IL- 12Rβ1-independent pathway of IL-12 responsiveness in human T cells. J. Exp. Med. 2000. 192: 517-528.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 517-528
-
-
Verhagen, C.E.1
de Boer, T.2
Smits, H.H.3
Verreck, F.A.4
Wierange, E.A.5
Kurimoto, M.6
Lammas, D.A.7
Kumararatne, D.S.8
Sanal, O.9
Kroon, F.P.10
-
8
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G. and Glimcher, L. H., A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000. 100: 655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
9
-
-
0035910037
-
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells
-
Lighvani, A. A., Frucht, D. M., Jankovic, D., Yamane, H., Aliberti, J., Hissong, B. D., Nguyen, B. V., Gadina, M., Sher, A., Paul, W. E. and O'Shea, J. J., T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. USA 2001. 98: 15137-15142.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15137-15142
-
-
Lighvani, A.A.1
Frucht, D.M.2
Jankovic, D.3
Yamane, H.4
Aliberti, J.5
Hissong, B.D.6
Nguyen, B.V.7
Gadina, M.8
Sher, A.9
Paul, W.E.10
O'Shea, J.J.11
-
10
-
-
0028303170
-
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells
-
Kubin, M., Kamoun, M. and Trinchieri, G., Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J. Exp. Med. 1994. 180: 211-222.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 211-222
-
-
Kubin, M.1
Kamoun, M.2
Trinchieri, G.3
-
11
-
-
0035059368
-
Interleukin-18 regulates both Th1 and Th2 responses
-
Nakanishi, K., Yoshimoto, T., Tsutsui, H. and Okamura, H., Interleukin-18 regulates both Th1 and Th2 responses. Annu. Rev. Immunol. 2001. 19: 423-474.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 423-474
-
-
Nakanishi, K.1
Yoshimoto, T.2
Tsutsui, H.3
Okamura, H.4
-
12
-
-
0032577295
-
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
-
de Jong, R., Altars, F., Haagen, I. A., Elferink, D. G., de Boer, T., Breda Vriesman, P. J., Kabel, P. J., Draaisma, J. M., Van Diesel, J. T., Kroon, F. P. et al., Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. Science 1998. 280: 1435-1438.
-
(1998)
Science
, vol.280
, pp. 1435-1438
-
-
de Jong, R.1
Altars, F.2
Haagen, I.A.3
Elferink, D.G.4
de Boer, T.5
Breda Vriesman, P.J.6
Kabel, P.J.7
Draaisma, J.M.8
Van Diesel, J.T.9
Kroon, F.P.10
-
13
-
-
0037365157
-
Genetic variations in the interleukin-12/ interleukin-23 receptor (β1) chain, and implications for IL-12 and IL-23 receptor structure and function
-
Van de Vosse, E., Lichtenauer-Kaligis, E. G., van Dissel, J. T. and Ottenhoff T. H., Genetic variations in the interleukin-12/ interleukin-23 receptor (β1) chain, and implications for IL-12 and IL-23 receptor structure and function. Immunogenetics 2003. 54: 817-829.
-
(2003)
Immunogenetics
, vol.54
, pp. 817-829
-
-
Van de Vosse, E.1
Lichtenauer-Kaligis, E.G.2
van Dissel, J.T.3
Ottenhoff, T.H.4
-
14
-
-
0037218610
-
Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency
-
Cleary, A. M., Tu, W., Enright, A., Giffon, T., Dewaal-Malefyt, R., Gutierrez, K. and Lewis, D. B., Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency. J. Immunol. 2003. 170: 597-603.
-
(2003)
J. Immunol.
, vol.170
, pp. 597-603
-
-
Cleary, A.M.1
Tu, W.2
Enright, A.3
Giffon, T.4
Dewaal-Malefyt, R.5
Gutierrez, K.6
Lewis, D.B.7
-
15
-
-
0031707741
-
Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans
-
Decken, K., Kohler, G., Palmer-Lehmann, K., Wunderlin, A., Mattner, F., Magram, J., Gately, M. K. and Alber, G., Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans. Infect. Immun. 1998. 66: 4994-5000.
-
(1998)
Infect. Immun.
, vol.66
, pp. 4994-5000
-
-
Decken, K.1
Kohler, G.2
Palmer-Lehmann, K.3
Wunderlin, A.4
Mattner, F.5
Magram, J.6
Gately, M.K.7
Alber, G.8
-
16
-
-
0344958627
-
IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes
-
Brombacher, F., Dorfmuller A., Magram, J., Dai, W. J., Kohler, G., Wunderlin, A., Palmer-Lehmann, K., Gately, M. K. and Alber, A., IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes. Int. Immunol. 1999. 11: 325-332.
-
(1999)
Int. Immunol.
, vol.11
, pp. 325-332
-
-
Brombacher, F.1
Dorfmuller, A.2
Magram, J.3
Dai, W.J.4
Kohler, G.5
Wunderlin, A.6
Palmer-Lehmann, K.7
Gately, M.K.8
Alber, A.9
-
17
-
-
0034541139
-
IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites
-
Wu, C., Wang, X, Gadina, M., O'Shea, J. J., Presky D. H. and Magram, J., IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites. J. Immunol. 2000. 165: 6221-6228.
-
(2000)
J. Immunol.
, vol.165
, pp. 6221-6228
-
-
Wu, C.1
Wang, X.2
Gadina, M.3
O'Shea, J.J.4
Presky, D.H.5
Magram, J.6
-
18
-
-
0036467445
-
Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present
-
Cooper, A. M., Kipnis, A., Turner, J., Magram, J., Ferrante, J. and Orme, I. M., Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present. J. Immunol. 2002. 168: 1322-1327.
-
(2002)
J. Immunol.
, vol.168
, pp. 1322-1327
-
-
Cooper, A.M.1
Kipnis, A.2
Turner, J.3
Magram, J.4
Ferrante, J.5
Orme, I.M.6
-
19
-
-
0036127059
-
In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70
-
Elkins, K. L., Cooper, A., Colombini, S. M., Cowley, S. C. and Kieffer, T. L., In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70. Infect Immun. 2002. 70: 1936-1948.
-
(2002)
Infect. Immun.
, vol.70
, pp. 1936-1948
-
-
Elkins, K.L.1
Cooper, A.2
Colombini, S.M.3
Cowley, S.C.4
Kieffer, T.L.5
-
20
-
-
0036604062
-
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells
-
Belladonna, M. L., Renauld, J. C., Bianchi, R., Vacca, C., Fallsrino, F., Orabona, C., Fioretti, M. C., Grohmann, U. and Puccetti, P., IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. J. Immunol. 2002. 168: 5448-5454.
-
(2002)
J. Immunol.
, vol.168
, pp. 5448-5454
-
-
Belladonna, M.L.1
Renauld, J.C.2
Bianchi, R.3
Vacca, C.4
Fallsrino, F.5
Orabona, C.6
Fioretti, M.C.7
Grohmann, U.8
Puccetti, P.9
-
21
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
Wiekowski, M. T., Leach, M. W., Evans, E. W., Sullivan, L., Chen, S. C., Vassileva, G., Bazan, J. F., Gorman, D. M., Kastelein, R. A., Narula, S. and Lira, S. A., Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J. Immunol. 2001. 166: 7563-7570.
-
(2001)
J. Immunol.
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
Bazan, J.F.7
Gorman, D.M.8
Kastelein, R.A.9
Narula, S.10
Lira, S.A.11
-
22
-
-
0037449737
-
Interleukin 23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin 17
-
Aggarwal, S., Ghilardi, N., Xie, M. H., de Sauvage, F. J. and Gurney, A. L., Interleukin 23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin 17. J. Biol. Chem. 2002. 278: 1910-1914.
-
(2002)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
de Sauvage, F.J.4
Gurney, A.L.5
-
23
-
-
0242584872
-
Cutting Edge: Roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection
-
Happel, K. I., Zheng, M., Young, E., Quinton, L. J., Lockhart, E., Ramsay, A. J., Shellito, J. E., Schurr, J. R., Bagby, G. J., Nelson, S. and Kolls, J. K., Cutting Edge: Roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J. Immunol. 2003. 170: 4432-4436.
-
(2003)
J. Immunol.
, vol.170
, pp. 4432-4436
-
-
Happel, K.I.1
Zheng, M.2
Young, E.3
Quinton, L.J.4
Lockhart, E.5
Ramsay, A.J.6
Shellito, J.E.7
Schurr, J.R.8
Bagby, G.J.9
Nelson, S.10
Kolls, J.K.11
|