-
1
-
-
0344464720
-
Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
-
R. Nusse Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface Development 130 2003 5297 5305
-
(2003)
Development
, vol.130
, pp. 5297-5305
-
-
Nusse, R.1
-
2
-
-
2942738996
-
The Hedgehog response network: Sensors, switches, and routers
-
L. Lum, and P.A. Beachy The Hedgehog response network: sensors, switches, and routers Science 304 2004 1755 1759
-
(2004)
Science
, vol.304
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
3
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
K. Willert, J.D. Brown, E. Danenberg, A.W. Duncan, I.L. Weissman, and T. Reya Wnt proteins are lipid-modified and can act as stem cell growth factors Nature 423 2003 448 452
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
-
4
-
-
13644269949
-
Wnt signalling and the mechanistic basis of tumour development
-
M. Ilyas Wnt signalling and the mechanistic basis of tumour development J. Pathol. 205 2005 130 144
-
(2005)
J. Pathol.
, vol.205
, pp. 130-144
-
-
Ilyas, M.1
-
5
-
-
19644373254
-
Wnt signaling in disease and in development
-
R. Nusse Wnt signaling in disease and in development Cell Res. 15 2005 28 32
-
(2005)
Cell Res.
, vol.15
, pp. 28-32
-
-
Nusse, R.1
-
6
-
-
18344377028
-
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations
-
B.A. He, N. Reguart, L. You, J. Mazieres, Z.D. Xu, and A.Y. Lee Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations Oncogene 24 2005 3054 3058
-
(2005)
Oncogene
, vol.24
, pp. 3054-3058
-
-
He, B.A.1
Reguart, N.2
You, L.3
Mazieres, J.4
Xu, Z.D.5
Lee, A.Y.6
-
7
-
-
0033118492
-
A new secreted protein that binds to Wnt proteins and inhibits their activities
-
J.C. Hsieh, L. Kodjabachian, M.L. Rebbert, A. Rattner, P.M. Smallwood, and C.H. Samos A new secreted protein that binds to Wnt proteins and inhibits their activities Nature 398 1999 431 436
-
(1999)
Nature
, vol.398
, pp. 431-436
-
-
Hsieh, J.C.1
Kodjabachian, L.2
Rebbert, M.L.3
Rattner, A.4
Smallwood, P.M.5
Samos, C.H.6
-
8
-
-
9144234206
-
The extracellular matrix component WIF-1 is expressed during, and can modulate, retinal development
-
D.D. Hunter, M.L. Zhang, J.W. Ferguson, M. Koch, and W.J. Brunken The extracellular matrix component WIF-1 is expressed during, and can modulate, retinal development Mol. Cell. Neurosci. 27 2004 477 488
-
(2004)
Mol. Cell. Neurosci.
, vol.27
, pp. 477-488
-
-
Hunter, D.D.1
Zhang, M.L.2
Ferguson, J.W.3
Koch, M.4
Brunken, W.J.5
-
9
-
-
0141995804
-
WIF-1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
-
C. Wissmann, P.J. Wild, S. Kaiser, S. Roepcke, R. Stoehr, and M. Woenckhaus WIF-1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer J. Pathol. 201 2003 204 212
-
(2003)
J. Pathol.
, vol.201
, pp. 204-212
-
-
Wissmann, C.1
Wild, P.J.2
Kaiser, S.3
Roepcke, S.4
Stoehr, R.5
Woenckhaus, M.6
-
10
-
-
3142679453
-
Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
-
J. Mazieres, B. He, L. You, Z.D. Xu, A.Y. Lee, and I. Mikami Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer Cancer Res. 64 2004 4717 4720
-
(2004)
Cancer Res.
, vol.64
, pp. 4717-4720
-
-
Mazieres, J.1
He, B.2
You, L.3
Xu, Z.D.4
Lee, A.Y.5
Mikami, I.6
-
11
-
-
10144237223
-
Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells
-
T. Ohigashi, R. Mizuno, J. Nakashima, K. Marumo, and M. Murai Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells Prostate 62 2005 61 68
-
(2005)
Prostate
, vol.62
, pp. 61-68
-
-
Ohigashi, T.1
Mizuno, R.2
Nakashima, J.3
Marumo, K.4
Murai, M.5
-
12
-
-
1442335374
-
Wnt inhibitory factor-1: A candidate for a new player in tumorigenesis of intestinal epithelial cells
-
M. Cebrat, L. Strzadala, and P. Kisielow Wnt inhibitory factor-1: a candidate for a new player in tumorigenesis of intestinal epithelial cells Cancer Letters 206 2004 107 113
-
(2004)
Cancer Letters
, vol.206
, pp. 107-113
-
-
Cebrat, M.1
Strzadala, L.2
Kisielow, P.3
-
14
-
-
5344273899
-
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
-
W.G. Lu, V. Yamamoto, B. Ortega, and D. Baltimore Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth Cell 119 2004 97 108
-
(2004)
Cell
, vol.119
, pp. 97-108
-
-
Lu, W.G.1
Yamamoto, V.2
Ortega, B.3
Baltimore, D.4
-
15
-
-
0029752981
-
H-Ryk, an unusual receptor kinase - Isolation and analysis of expression in ovarian cancer
-
X.C. Wang, R. Katso, R. Butler, A.M. Hanby, R. Poulsom, and T. Jones H-Ryk, an unusual receptor kinase - isolation and analysis of expression in ovarian cancer Mol. Med. 2 1996 189 203
-
(1996)
Mol. Med.
, vol.2
, pp. 189-203
-
-
Wang, X.C.1
Katso, R.2
Butler, R.3
Hanby, A.M.4
Poulsom, R.5
Jones, T.6
-
16
-
-
0033871087
-
Overexpression of h-Ryk in epithelial ovarian cancer: Prognostic significance of receptor expression
-
R.M.T. Katso, S. Manek, H. Ganjavi, S. Biddolph, M.F.L. Charnock, and M. Bradburn Overexpression of h-Ryk in epithelial ovarian cancer: prognostic significance of receptor expression Clin. Cancer Res. 6 2000 3271 3281
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3271-3281
-
-
Katso, R.M.T.1
Manek, S.2
Ganjavi, H.3
Biddolph, S.4
Charnock, M.F.L.5
Bradburn, M.6
-
17
-
-
0033563245
-
Overexpression of h-Ryk in mouse fibroblasts confers transforming ability in vitro and in vivo: Correlation with up-regulation in epithelial ovarian cancer
-
R.M.T. Katso, S. Manek, S. Biddolph, R. Whittaker, M.F.L. Charnock, M. Wells, and T.S. Ganesan Overexpression of h-Ryk in mouse fibroblasts confers transforming ability in vitro and in vivo: correlation with up-regulation in epithelial ovarian cancer Cancer Res. 59 1999 2265 2270
-
(1999)
Cancer Res.
, vol.59
, pp. 2265-2270
-
-
Katso, R.M.T.1
Manek, S.2
Biddolph, S.3
Whittaker, R.4
Charnock, M.F.L.5
Wells, M.6
Ganesan, T.S.7
-
18
-
-
0034426014
-
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk
-
M.M. Halford, J. Armes, M. Buchert, V. Meskenaite, D. Grail, and M.L. Hibbs Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk Nature Genet. 25 2000 414 418
-
(2000)
Nature Genet.
, vol.25
, pp. 414-418
-
-
Halford, M.M.1
Armes, J.2
Buchert, M.3
Meskenaite, V.4
Grail, D.5
Hibbs, M.L.6
-
19
-
-
4544329969
-
C. elegans LIN-18 is a Ryk ortholog in parallel to LIN-17/frizzled in Wnt and functions signalling
-
T. Inoue, H.S. Oz, D. Wiland, S. Gharib, R. Deshpande, and R.J. Hill C. elegans LIN-18 is a Ryk ortholog in parallel to LIN-17/frizzled in Wnt and functions signalling Cell 118 2004 795 806
-
(2004)
Cell
, vol.118
, pp. 795-806
-
-
Inoue, T.1
Oz, H.S.2
Wiland, D.3
Gharib, S.4
Deshpande, R.5
Hill, R.J.6
-
20
-
-
0028829060
-
Molecular cloning of linotte in Drosophila - A novel gene that functions in adults during associative learning
-
G.M. Bolwig, M. Del Vecchio, G. Hannon, and T. Tully Molecular cloning of linotte in Drosophila - a novel gene that functions in adults during associative learning Neuron 15 1995 829 842
-
(1995)
Neuron
, vol.15
, pp. 829-842
-
-
Bolwig, G.M.1
Del Vecchio, M.2
Hannon, G.3
Tully, T.4
-
21
-
-
0029152179
-
The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human Ryk gene product
-
J.M. Dura, E. Taillebourg, and T. Preat The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human Ryk gene product FEBS Letters 370 1995 250 254
-
(1995)
FEBS Letters
, vol.370
, pp. 250-254
-
-
Dura, J.M.1
Taillebourg, E.2
Preat, T.3
-
22
-
-
0031649606
-
Embryonic expression and activity of doughnut, a second Ryk homolog in Drosophila
-
A.C. Oates, J.L. Bonkovsky, D.V. Irvine, L.E. Kelly, J.B. Thomas, and A.F. Wilks Embryonic expression and activity of doughnut, a second Ryk homolog in Drosophila Mech. Dev. 78 1998 165 169
-
(1998)
Mech. Dev.
, vol.78
, pp. 165-169
-
-
Oates, A.C.1
Bonkovsky, J.L.2
Irvine, D.V.3
Kelly, L.E.4
Thomas, J.B.5
Wilks, A.F.6
-
23
-
-
0033614488
-
A Drosophila Derailed homolog, Doughnut, expressed in invaginating cells during embryogenesis
-
S. Savant-Bhonsale, M. Friese, P. McCoon, and D.J. Montell A Drosophila Derailed homolog, Doughnut, expressed in invaginating cells during embryogenesis Gene 231 1999 155 161
-
(1999)
Gene
, vol.231
, pp. 155-161
-
-
Savant-Bhonsale, S.1
Friese, M.2
McCoon, P.3
Montell, D.J.4
-
24
-
-
13244292984
-
Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog
-
B. Glise, C.A. Miller, M. Crozatier, M.A. Halbisen, S. Wise, and D.J. Olson Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog Dev. Cell 8 2005 255 266
-
(2005)
Dev. Cell
, vol.8
, pp. 255-266
-
-
Glise, B.1
Miller, C.A.2
Crozatier, M.3
Halbisen, M.A.4
Wise, S.5
Olson, D.J.6
-
25
-
-
13244257603
-
The Drosophila ortholog of the human Wnt inhibitor factor shifted controls the diffusion of lipid-modified hedgehog
-
N. Gorfinkiel, J. Sierra, A. Callejo, C. Ibañez, and I. Guerrero The Drosophila ortholog of the human Wnt inhibitor factor shifted controls the diffusion of lipid-modified hedgehog Dev. Cell 8 2005 241 253
-
(2005)
Dev. Cell
, vol.8
, pp. 241-253
-
-
Gorfinkiel, N.1
Sierra, J.2
Callejo, A.3
Ibañez, C.4
Guerrero, I.5
-
26
-
-
0037431230
-
Wnt-mediated axon guidance via the Drosophila derailed receptor
-
S. Yoshikawa, R.D. McKinnon, M. Kokel, and J.B. Thomas Wnt-mediated axon guidance via the Drosophila derailed receptor Nature 422 2003 583 588
-
(2003)
Nature
, vol.422
, pp. 583-588
-
-
Yoshikawa, S.1
McKinnon, R.D.2
Kokel, M.3
Thomas, J.B.4
-
27
-
-
2942742564
-
Novel lipid modifications of secreted protein signals
-
R.K. Mann, and P.A. Beachy Novel lipid modifications of secreted protein signals Annu. Rev. Biochem. 73 2004 891 923
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 891-923
-
-
Mann, R.K.1
Beachy, P.A.2
-
28
-
-
0029889988
-
PHD: Predicting one-dimensional protein structure by profile-based neural networks
-
B. Rost PHD: predicting one-dimensional protein structure by profile-based neural networks Methods Enzymol. 266 1996 525 539
-
(1996)
Methods Enzymol.
, vol.266
, pp. 525-539
-
-
Rost, B.1
-
29
-
-
0033003335
-
Protein backbone angle restraints from searching a database for chemical shift and sequence homology
-
G. Cornilescu, F. Delaglio, and A. Bax Protein backbone angle restraints from searching a database for chemical shift and sequence homology J. Biomol. NMR 13 1999 289 302
-
(1999)
J. Biomol. NMR
, vol.13
, pp. 289-302
-
-
Cornilescu, G.1
Delaglio, F.2
Bax, A.3
-
30
-
-
0027104123
-
Ryk, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs
-
C.M. Hovens, S.A. Stacker, A. Andres, A.G. Harpur, A. Ziemiecki, and A.F. Wilks Ryk, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs Proc. Natl Acad. Sci. USA 89 1992 11818 11822
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 11818-11822
-
-
Hovens, C.M.1
Stacker, S.A.2
Andres, A.3
Harpur, A.G.4
Ziemiecki, A.5
Wilks, A.F.6
-
31
-
-
0035138936
-
Revelations of the Ryk receptor
-
M.M. Halford, and S.A. Stacker Revelations of the Ryk receptor Bioessays 23 2001 34 45
-
(2001)
Bioessays
, vol.23
, pp. 34-45
-
-
Halford, M.M.1
Stacker, S.A.2
-
32
-
-
0031715982
-
A database and tools for 3-D protein structure comparison and alignment using the combinatorial extension (CE) algorithm
-
I.N. Shindyalov, and P.E. Bourne A database and tools for 3-D protein structure comparison and alignment using the combinatorial extension (CE) algorithm Protein Eng. 11 1998 739 747
-
(1998)
Protein Eng.
, vol.11
, pp. 739-747
-
-
Shindyalov, I.N.1
Bourne, P.E.2
-
33
-
-
0027440362
-
Protein structure comparison by alignment of distance matrices
-
L. Holm, and C. Sander Protein structure comparison by alignment of distance matrices J. Mol. Biol. 233 1993 123 136
-
(1993)
J. Mol. Biol.
, vol.233
, pp. 123-136
-
-
Holm, L.1
Sander, C.2
-
34
-
-
0034603198
-
Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator
-
G.R. Hoffman, N. Nassar, and R.A. Cerione Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator Cell 100 2000 345 356
-
(2000)
Cell
, vol.100
, pp. 345-356
-
-
Hoffman, G.R.1
Nassar, N.2
Cerione, R.A.3
-
35
-
-
0036094156
-
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection
-
C.S. Hung, J. Bouckaert, D. Hung, J. Pinkner, C. Widberg, and A. DeFusco Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection Mol. Microbiol. 44 2002 903 915
-
(2002)
Mol. Microbiol.
, vol.44
, pp. 903-915
-
-
Hung, C.S.1
Bouckaert, J.2
Hung, D.3
Pinkner, J.4
Widberg, C.5
Defusco, A.6
-
36
-
-
0031570337
-
A modulator of Rho family G proteins, RhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm
-
N.H. Keep, M. Barnes, I. Barsukov, R. Badii, L.Y. Lian, and A.W. Segal A modulator of Rho family G proteins, RhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm Structure 5 1997 623 633
-
(1997)
Structure
, vol.5
, pp. 623-633
-
-
Keep, N.H.1
Barnes, M.2
Barsukov, I.3
Badii, R.4
Lian, L.Y.5
Segal, A.W.6
-
37
-
-
0020997912
-
Dictionary of protein secondary structure - Pattern-recognition of hydrogen-bonded and geometrical features
-
W. Kabsch, and C. Sander Dictionary of protein secondary structure - pattern-recognition of hydrogen-bonded and geometrical features Biopolymers 22 1983 2577 2637
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
38
-
-
0000088628
-
Processing of multidimensional NMR data with the new software PROSA
-
P. Güntert, V. Dötsch, G. Wider, and K. Wüthrich Processing of multidimensional NMR data with the new software PROSA J. Biomol. NMR 2 1992 619 629
-
(1992)
J. Biomol. NMR
, vol.2
, pp. 619-629
-
-
Güntert, P.1
Dötsch, V.2
Wider, G.3
Wüthrich, K.4
-
39
-
-
0343459675
-
The program XEASY for computer-supported NMR spectral analysis
-
C. Bartels, T. Xia, P. Güntert, M. Billeter, and K. Wüthrich The program XEASY for computer-supported NMR spectral analysis J. Biomol. NMR 5 1995 1 10
-
(1995)
J. Biomol. NMR
, vol.5
, pp. 1-10
-
-
Bartels, C.1
Xia, T.2
Güntert, P.3
Billeter, M.4
Wüthrich, K.5
-
40
-
-
0031576336
-
Torsion angle dynamics for NMR structure calculation with the new program DYANA
-
P. Güntert, C. Mumenthaler, and K. Wüthrich Torsion angle dynamics for NMR structure calculation with the new program DYANA J. Mol. Biol. 273 1997 283 298
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 283-298
-
-
Güntert, P.1
Mumenthaler, C.2
Wüthrich, K.3
-
41
-
-
0030236215
-
The new program OPAL for molecular dynamics simulations and energy refinements of biological macromolecules
-
P. Luginbühl, P. Güntert, M. Billeter, and K. Wüthrich The new program OPAL for molecular dynamics simulations and energy refinements of biological macromolecules J. Biomol. NMR 8 1996 136 146
-
(1996)
J. Biomol. NMR
, vol.8
, pp. 136-146
-
-
Luginbühl, P.1
Güntert, P.2
Billeter, M.3
Wüthrich, K.4
-
42
-
-
0030339738
-
AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
-
R.A. Laskowski, J.A.C. Rullmann, M.W. MacArthur, R. Kaptein, and J.M. Thornton AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR J. Biomol. NMR 8 1996 477 486
-
(1996)
J. Biomol. NMR
, vol.8
, pp. 477-486
-
-
Laskowski, R.A.1
Rullmann, J.A.C.2
MacArthur, M.W.3
Kaptein, R.4
Thornton, J.M.5
-
43
-
-
0029881007
-
MOLMOL: A program for display and analysis of macromolecular structures
-
R. Koradi, M. Billeter, and K. Wüthrich MOLMOL: a program for display and analysis of macromolecular structures J. Mol. Graph. 14 1996 51 55
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 51-55
-
-
Koradi, R.1
Billeter, M.2
Wüthrich, K.3
-
44
-
-
0028063876
-
Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor(1-76) in solution and comparison with the DNA-binding domain of the 434 repressor
-
P. Sevilla-Sierra, G. Otting, and K. Wüthrich Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor(1-76) in solution and comparison with the DNA-binding domain of the 434 repressor J. Mol. Biol. 235 1993 1003 1020
-
(1993)
J. Mol. Biol.
, vol.235
, pp. 1003-1020
-
-
Sevilla-Sierra, P.1
Otting, G.2
Wüthrich, K.3
|