Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection

Molecular Microbiology

Volumn 44, Issue 4, 2002, Pages 903-915

  Hung, Chia Suei ^a   Bouckaert, Julie ^a,b   Hung, Danielle ^a   Pinkner, Jerome ^a   Widberg, Charlotte ^a   DeFusco, Anthony ^c   Auguste, C Gale ^c   Strouse, Robert ^c   Langermann, Solomon ^c   Waksman, Gabriel ^a   Hultgren, Scott J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; MANNOSE; MANNOSE BINDING PROTEIN; MANNOTRIOSE; PROTEIN FIMH; TRIOSE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ATTENUATION; BACTERIAL STRAIN; BACTERIUM ADHERENCE; BINDING AFFINITY; BINDING SITE; BLADDER; CONTROLLED STUDY; CRYSTALLOGRAPHY; EPITHELIUM CELL; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STRAIN DIFFERENCE; STRUCTURE ACTIVITY RELATION; URINARY TRACT; URINARY TRACT INFECTION;

ADHESINS, BACTERIAL; ADHESINS, ESCHERICHIA COLI; AMINO ACID SEQUENCE; BACTERIAL ADHESION; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; HUMANS; MANNOSE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; URINARY BLADDER; URINARY TRACT INFECTIONS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0036094156     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.02915.x     Document Type: Article

References (50)

1. Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic
2. PapD-like chaperones provide the missing information for folding of pilin proteins
3. Type 1 fimbriae mutants of Escherichia coli K12: Characterization of recognized afimbriate strains and construction of new fim deletion mutants
4. The crystal structures of Man (α1-3) Man (α1-O) Me and Man (α1-6) Man (α1-O) Me in complex with concanavalin A
5. The structure, function, synthesis, and genetic control of bacterial pili and a model for DNA and RNA transport in Gram-negative bacteria
6. Crystallography and NMR system: A new software suite for macromolecular structure determination
7. X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli
8. Shiga toxin binds human platelets via globotriaosylceramide (Pk antigen) and a novel platelet glycosphingolipid
9. Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor
10. Measurement of invasion by gentamicin resistance
11. An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium
12. Carbohydrate specificity of the surface lectins of Escherichia coli, Klebsiella pneumoniae and Salmonella typhimurium
13. Carbohydrate-binding sites of the mannose-specific fimbrial lectins of Enterobacteria
14. Aromatic α-glycosides of mannose are powerful inhibitors of the adherence of type 1 fimbriated Escherichia coli to yeast and intestinal cells
15. Molecular cloning of the plasmid RP4 primase region in a multi-hostrange tacP expression vector
16. Two cases of non-O157: H7 Escherichia coli hemolytic uremic syndrome caused by urinary tract infection
17. Diagnosis and treatment of uncomplicated urinary tract infections
18. Mannose-sensitive hemagglutination in the absence of piliation in Escherichia coli
19. Probing conserved surfaces on PapD
20. FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae
21. Induction of apoptosis in normal human renal tubular epithelial cells by Escherichia coli Shiga toxins 1 and 2
22. Bacterial adhesins: Structural studies reveal chaperone function and pilus biogenesis
23. Basement membrane carbohydrate as a target for bacterial adhesion: Binding of type 1 fimbriae of Salmonella enterica and Escherichia colito laminin
24. Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination
25. Type 1 pilus-mediated invasion of bladder epithelial cells by uropathogenic Escherichia coli
26. Shiga toxin-producing Escherichia coli urinary tract infection associated with hemolyticuremic syndrome in an adult and possible adverse effect of ofloxacin therapy
27. The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit
28. Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli
29. Refined structure of concanavalin A complexed with α-methyl-D-mannopy-rannoside at 2.0 Å resolution and comparison with the saccharide free structure
30. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
31. Enterohemorrhagic Escherichia coli: A family of emerging pathogens
32. Organization and expression of genes responsible for type 1 piliation in Escherichia coli
33. Processing of X-ray diffraction data collected in oscillation mode
34. Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors
35. Amino acid residue Ala-62 in the FimH fimbrial adhesin is critical for the adhesiveness of meningitis-associated Escherichia coli to collagens
36. Genetic analyses of bacterial biofilm formation
37. Bacteriophage I vectors
38. Structural basis of chaperone function and pilus biogenesis
39. PapD-like chaperones and pilus biogenesis
40. Functional flexibility of the FimH adhesin: Insights from arandom mutant library
41. Interactive surface in the PapD chaperone cleft is conserved in pilus chaperone superfamily and essential in subunit recognition and assembly
42. Diversity of the Escherichia coli type 1 fimbrial lectin. Differential binding to mannosides and uroepithelial cells
43. Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin
44. Quantitative differences in adhesiveness of type 1 fimbriated Escherichia coli due to structural differences in fimH genes
45. Valency conversion in the type 1 fimbrial adhesin of Escherichia coli
46. Bacterial adhesins: Common themes and variations in architecture and assembly
47. Hemolytic-uremic syndrome following urinary tract infection with enterohemorrhagic Escherichia coli: Case report and review
48. Structural requirements for the glycolipid receptor of human uropathogenic E. coli
49. Host/vector interactions which affect the variability of recombinant phage lambda clones
50. In vitro binding of type 1-fimbriated Escherichia coli to uroplakins 1a and 1b: Relation to urinary tract infections