Oligomerization of the γ-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 55728-55736

  Korkhov, Vladimir M ^a   Farhan, Hesso ^a   Freissmuth, Michael ^a   Sitte, Harald H ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; ENERGY TRANSFER; HYDROGEN BONDS; HYDROPHOBICITY; NEUROLOGY; ORGANIC ACIDS; PROTEINS;

Γ-AMINOBUTYRIC ACID; FOERSTER RESONANCE ENERGY TRANSFER; HYDROPHOBIC INTERACTIONS; NEUROTRANSMITTERS; OLIGOMERIZATION;

OLIGOMERS;

BETA LACTAMASE; CARRIER PROTEIN; GAMMA AMINOBUTYRIC ACID TRANSPORTER 1; GLUTAMINE; LEUCINE; MUTANT PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; NEUROTRANSMISSION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN TRANSPORT; TRANSMEMBRANE HELIX 2;

AMINO ACID SEQUENCE; BETA-LACTAMASES; CELL LINE; DIMERIZATION; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; FLUORESCENCE RESONANCE ENERGY TRANSFER; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GENETIC COMPLEMENTATION TEST; GLUTAMIC ACID; HUMANS; HYDROGEN BONDING; KINETICS; LEUCINE; LIGHT; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM; TIME FACTORS; TYROSINE;

EID: 11244255410     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409449200     Document Type: Article

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