Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats

Journal of Neurophysiology

Volumn 95, Issue 1, 2006, Pages 18-25

  McGaraughty, Steve ^a   Chu, Katharine L ^a   Faltynek, Connie R ^a   Jarvis, Michael F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 425619; CAPSAICIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; 1 ISOQUINOLIN 5 YL 3 (4 TRIFLUOROMETHYL BENZYL) UREA; 1-ISOQUINOLIN-5-YL-3-(4-TRIFLUOROMETHYL-BENZYL)-UREA; DRUG DERIVATIVE; FREUND ADJUVANT; ISOQUINOLINE DERIVATIVE; TRPV1 PROTEIN, RAT; UREA; VANILLOID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; CELL DAMAGE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; NERVE CELL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; THERMAL STIMULATION; ACTION POTENTIAL; ANIMAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; EVOKED SOMATOSENSORY RESPONSE; HYPERALGESIA; MALE; PATHOPHYSIOLOGY; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; EVOKED POTENTIALS, SOMATOSENSORY; FREUND'S ADJUVANT; GANGLIA, SPINAL; HYPERALGESIA; ISOQUINOLINES; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TRPV CATION CHANNELS; UREA;

EID: 33644805715     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00560.2005     Document Type: Article

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