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Volumn 28, Issue 5, 2005, Pages 333-342

The role of BAFF in autoimmune diseases

Author keywords

B cell homeostasis; BAFF; rheumatic disease; self reactive B cells

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; MEMBRANE PROTEIN; TNFRSF13C PROTEIN, HUMAN; TNFSF13B PROTEIN, HUMAN; TNFSF13B PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 33644693521     PISSN: 09114300     EISSN: 13497413     Source Type: Journal    
DOI: 10.2177/jsci.28.333     Document Type: Article
Times cited : (15)

References (64)
  • 1
    • 0033538468 scopus 로고    scopus 로고
    • BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
    • Moore P. A., Belvedere O., Orr A., et al.: BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285: 260–263, 1999.
    • (1999) Science , vol.285 , pp. 260-263
    • Moore, P.A.1    Belvedere, O.2    Orr, A.3
  • 2
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
    • Schneider P., MacKay F., Steiner V., et al.: BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 189: 1747–1756, 1999.
    • (1999) J Exp Med , vol.189 , pp. 1747-1756
    • Schneider, P.1    MacKay, F.2    Steiner, V.3
  • 3
    • 0032915632 scopus 로고    scopus 로고
    • TALL-1 is a novel member of the TNF family that is downregulated by mitogens.
    • Shu H. B., Hu W. H., Johnson H: TALL-1 is a novel member of the TNF family that is downregulated by mitogens. J Leukoc Biol 65: 680–683, 1999.
    • (1999) J Leukoc Biol , vol.65 , pp. 680-683
    • Shu, H.B.1    Hu, W.H.2    Johnson, H.3
  • 4
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL.
    • Litinskiy M. B., Nardelli B., Hilbert D. M., et al.: DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 3: 822–829, 2002.
    • (2002) Nat Immunol , vol.3 , pp. 822-829
    • Litinskiy, M.B.1    Nardelli, B.2    Hilbert, D.M.3
  • 5
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells.
    • Nardelli B., Belvedere O., Roschke V., et al.: Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 97: 198–204, 2001.
    • (2001) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1    Belvedere, O.2    Roschke, V.3
  • 6
    • 10744223505 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity.
    • Hanada T., Yoshida H., Kato S., et al.: Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity. Immunity 19: 437–450, 2003.
    • (2003) Immunity , vol.19 , pp. 437-450
    • Hanada, T.1    Yoshida, H.2    Kato, S.3
  • 7
    • 0036221083 scopus 로고    scopus 로고
    • Structural basis of BLyS receptor recognition.
    • Oren D. A., Li Y., Volovik Y., et al.: Structural basis of BLyS receptor recognition. Nat Struct Biol 9: 288–292, 2002.
    • (2002) Nat Struct Biol , vol.9 , pp. 288-292
    • Oren, D.A.1    Li, Y.2    Volovik, Y.3
  • 8
    • 0036300545 scopus 로고    scopus 로고
    • Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes.
    • Karpusas M., Cachero T. G., Qian F., et al.: Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes. J Mol Biol 315: 1145–1154, 2002.
    • (2002) J Mol Biol , vol.315 , pp. 1145-1154
    • Karpusas, M.1    Cachero, T.G.2    Qian, F.3
  • 9
    • 0036183318 scopus 로고    scopus 로고
    • Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.
    • Liu Y., Xu L., Opalka N., et al.: Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell 108: 383–394, 2002.
    • (2002) Cell , vol.108 , pp. 383-394
    • Liu, Y.1    Xu, L.2    Opalka, N.3
  • 10
    • 0141643347 scopus 로고    scopus 로고
    • DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF.
    • Gavin A. L., Ait-Azzouzene D., Ware C. F., et al.: DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. J Biol Chem 278: 38220–38228, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 38220-38228
    • Gavin, A.L.1    Ait-Azzouzene, D.2    Ware, C.F.3
  • 11
    • 0032555931 scopus 로고    scopus 로고
    • APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.
    • Hahne M., Kataoka T., Schroter M., et al.: APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med 188: 1185–1190, 1998.
    • (1998) J Exp Med , vol.188 , pp. 1185-1190
    • Hahne, M.1    Kataoka, T.2    Schroter, M.3
  • 12
    • 0034652484 scopus 로고    scopus 로고
    • APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death.
    • Kelly K., Manos E., Jensen G., et al.: APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res 60: 1021–1027, 2000.
    • (2000) Cancer Res , vol.60 , pp. 1021-1027
    • Kelly, K.1    Manos, E.2    Jensen, G.3
  • 13
    • 0034764499 scopus 로고    scopus 로고
    • Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase.
    • Lopez-Fraga M., Fernandez R., Albar J. P., et al.: Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase. EMBO Rep 2: 945–951, 2001.
    • (2001) EMBO Rep , vol.2 , pp. 945-951
    • Lopez-Fraga, M.1    Fernandez, R.2    Albar, J.P.3
  • 14
    • 0037108490 scopus 로고    scopus 로고
    • BLyS and APRIL form biologically active het-erotrimers that are expressed in patients with systemic immune-based rheumatic diseases.
    • Roschke V., Sosnovtseva S., Ward C. D., et al.: BLyS and APRIL form biologically active het-erotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol 169: 4314–4321, 2002.
    • (2002) J Immunol , vol.169 , pp. 4314-4321
    • Roschke, V.1    Sosnovtseva, S.2    Ward, C.D.3
  • 15
    • 0036847318 scopus 로고    scopus 로고
    • An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein.
    • Pradet-Balade B., Medema J. P., Lopez-Fraga M., et al.: An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein. Embo J 21: 5711–5720, 2002.
    • (2002) Embo J , vol.21 , pp. 5711-5720
    • Pradet-Balade, B.1    Medema, J.P.2    Lopez-Fraga, M.3
  • 16
    • 0036634390 scopus 로고    scopus 로고
    • BAFF: a fundamental survival factor for B cells.
    • Mackay F., Browning JL: BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2: 465–475, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 465-475
    • Mackay, F.1    Browning, J.L.2
  • 17
    • 20044366916 scopus 로고    scopus 로고
    • Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.
    • Hymowitz S. G., Patel D. R., Wallweber H. J., et al.: Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J Biol Chem 280: 7218–7227, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 7218-7227
    • Hymowitz, S.G.1    Patel, D.R.2    Wallweber, H.J.3
  • 18
    • 1942469307 scopus 로고    scopus 로고
    • Engineering an APRIL-specific B cell maturation antigen.
    • Patel D. R., Wallweber H. J., Yin J., et al.: Engineering an APRIL-specific B cell maturation antigen. J Biol Chem 279: 16727–16735, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 16727-16735
    • Patel, D.R.1    Wallweber, H.J.2    Yin, J.3
  • 19
    • 0042858250 scopus 로고    scopus 로고
    • Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF.
    • Pelletier M., Thompson J. S., Qian F., et al.: Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF. J Biol Chem 278: 33127–33133, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 33127-33133
    • Pelletier, M.1    Thompson, J.S.2    Qian, F.3
  • 20
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifi-cally interacts with BAFF.
    • Thompson J. S., Bixler S. A., Qian F., et al.: BAFF-R, a newly identified TNF receptor that specifi-cally interacts with BAFF. Science 293: 2108–2111, 2001.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1    Bixler, S.A.2    Qian, F.3
  • 21
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency.
    • Yan M., Brady J. R., Chan B., et al.: Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 11: 1547–1552, 2001.
    • (2001) Curr Biol , vol.11 , pp. 1547-1552
    • Yan, M.1    Brady, J.R.2    Chan, B.3
  • 22
    • 20844432040 scopus 로고    scopus 로고
    • Identification of proteoglycans as the APRIL-specific binding partners.
    • Ingold K., Zumsteg A., Tardivel A., et al.: Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 201: 1375–1383, 2005.
    • (2005) J Exp Med , vol.201 , pp. 1375-1383
    • Ingold, K.1    Zumsteg, A.2    Tardivel, A.3
  • 23
    • 18844447818 scopus 로고    scopus 로고
    • The role of APRIL and BAFF in lymphocyte activation.
    • Schneider P: The role of APRIL and BAFF in lymphocyte activation. Curr Opin Immunol 17: 282–289, 2005.
    • (2005) Curr Opin Immunol , vol.17 , pp. 282-289
    • Schneider, P.1
  • 24
    • 16544363235 scopus 로고    scopus 로고
    • lymphocyte malignancies: exploitation of BLyS and APRIL and their receptors.
    • Jelinek D. F., Darce J.R. Human B., lymphocyte malignancies: exploitation of BLyS and APRIL and their receptors. Curr Dir Autoim-mun 8: 266–288, 2005.
    • (2005) Curr Dir Autoim-mun , vol.8 , pp. 266-288
    • Jelinek, D.F.1    Darce, J.R.2    Human, B.3
  • 25
    • 18644369740 scopus 로고    scopus 로고
    • BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
    • Kayagaki N., Yan M., Seshasayee D., et al.: BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 17: 515–524, 2002.
    • (2002) Immunity , vol.17 , pp. 515-524
    • Kayagaki, N.1    Yan, M.2    Seshasayee, D.3
  • 26
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.
    • Mackay F., Woodcock S. A., Lawton P., et al.: Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190: 1697–1710, 1999.
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3
  • 27
    • 4544318248 scopus 로고    scopus 로고
    • The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.
    • Tardivel A., Tinel A., Lens S., et al.: The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol 34: 509–518, 2004.
    • (2004) Eur J Immunol , vol.34 , pp. 509-518
    • Tardivel, A.1    Tinel, A.2    Lens, S.3
  • 28
    • 4043146475 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.
    • Shulga-Morskaya S., Dobles M., Walsh M. E., et al.: B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol 173: 2331–2341, 2004.
    • (2004) J Immunol , vol.173 , pp. 2331-2341
    • Shulga-Morskaya, S.1    Dobles, M.2    Walsh, M.E.3
  • 29
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.
    • Sasaki Y., Casola S., Kutok J. L., et al.: TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol 173: 2245–2252, 2004.
    • (2004) J Immunol , vol.173 , pp. 2245-2252
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3
  • 30
    • 0042697684 scopus 로고    scopus 로고
    • Enforced bcl-xL gene expression restored splenic B lymphocyte development in BAFF-R mutant mice.
    • Amanna I. J., Dingwall J. P., Hayes CE: Enforced bcl-xL gene expression restored splenic B lymphocyte development in BAFF-R mutant mice. J Immunol 170: 4593–4600, 2003.
    • (2003) J Immunol , vol.170 , pp. 4593-4600
    • Amanna, I.J.1    Dingwall, J.P.2    Hayes, C.E.3
  • 31
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells.
    • O'Connor B. P., Raman V. S., Erickson L. D., et al.: BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 199: 91–98, 2004.
    • (2004) J Exp Med , vol.199 , pp. 91-98
    • O'Connor, B.P.1    Raman, V.S.2    Erickson, L.D.3
  • 32
    • 1442288757 scopus 로고    scopus 로고
    • Autoimmunity, complement activation, tissue injury and reciprocal Effects.
    • Tsokos G. C., Fleming SD: Autoimmunity, complement activation, tissue injury and reciprocal Effects. Curr Dir Autoimmun 7: 149–164, 2004.
    • (2004) Curr Dir Autoimmun , vol.7 , pp. 149-164
    • Tsokos, G.C.1    Fleming, S.D.2
  • 33
    • 0034544489 scopus 로고    scopus 로고
    • Quantitative genetic variation in CD19 expression correlates with autoimmunity.
    • Sato S., Hasegawa M., Fujimoto M., et al.: Quantitative genetic variation in CD19 expression correlates with autoimmunity. J Immunol 165: 6635–6643, 2000.
    • (2000) J Immunol , vol.165 , pp. 6635-6643
    • Sato, S.1    Hasegawa, M.2    Fujimoto, M.3
  • 34
    • 12144286821 scopus 로고    scopus 로고
    • BAFF/ BLyS can potentiate B-cell selection with the B-cell coreceptor complex.
    • Hase H., Kanno Y., Kojima M., et al.: BAFF/ BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood 103: 2257–2265, 2004.
    • (2004) Blood , vol.103 , pp. 2257-2265
    • Hase, H.1    Kanno, Y.2    Kojima, M.3
  • 35
    • 9144244817 scopus 로고    scopus 로고
    • Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function.
    • Gorelik L., Cutler A. H., Thill G., et al.: Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function. J Immunol 172: 762–766, 2004.
    • (2004) J Immunol , vol.172 , pp. 762-766
    • Gorelik, L.1    Cutler, A.H.2    Thill, G.3
  • 36
    • 0038446862 scopus 로고    scopus 로고
    • Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function.
    • Vora K. A., Wang L. C., Rao S. P., et al.: Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function. J Immunol 171: 547–551, 2003.
    • (2003) J Immunol , vol.171 , pp. 547-551
    • Vora, K.A.1    Wang, L.C.2    Rao, S.P.3
  • 37
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.
    • Balazs M., Martin F., Zhou T., et al.: Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17: 341–352, 2002.
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balazs, M.1    Martin, F.2    Zhou, T.3
  • 38
    • 0034596831 scopus 로고    scopus 로고
    • Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response.
    • Do R. K., Hatada E., Lee H., et al.: Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J Exp Med 192: 953–964, 2000.
    • (2000) J Exp Med , vol.192 , pp. 953-964
    • Do, R.K.1    Hatada, E.2    Lee, H.3
  • 39
    • 7244223338 scopus 로고    scopus 로고
    • BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses.
    • Ye Q., Wang L., Wells A. D., et al.: BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol 34: 2750–2759, 2004.
    • (2004) Eur J Immunol , vol.34 , pp. 2750-2759
    • Ye, Q.1    Wang, L.2    Wells, A.D.3
  • 40
    • 16844364286 scopus 로고    scopus 로고
    • The BAFF/ APRIL system: life beyond B lymphocytes.
    • Ng L. G., Mackay C. R., Mackay F: The BAFF/ APRIL system: life beyond B lymphocytes. Mol Immunol 42: 763–772, 2005.
    • (2005) Mol Immunol , vol.42 , pp. 763-772
    • Ng, L.G.1    Mackay, C.R.2    Mackay, F.3
  • 41
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.
    • Gross J. A., Johnston J., Mudri S., et al.: TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404: 995–999, 2000.
    • (2000) Nature , vol.404 , pp. 995-999
    • Gross, J.A.1    Johnston, J.2    Mudri, S.3
  • 42
    • 12944249540 scopus 로고    scopus 로고
    • Severe B cell hyperplasia and autoimmune disease in TALL- 1 transgenic mice.
    • Khare S. D., Sarosi I., Xia X. Z., et al.: Severe B cell hyperplasia and autoimmune disease in TALL- 1 transgenic mice. Proc Natl Acad Sci U S A 97: 3370–3375, 2000.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3370-3375
    • Khare, S.D.1    Sarosi, I.2    Xia, X.Z.3
  • 43
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice.
    • Yan M., Wang H., Chan B., et al.: Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2: 638–643, 2001.
    • (2001) Nat Immunol , vol.2 , pp. 638-643
    • Yan, M.1    Wang, H.2    Chan, B.3
  • 44
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.
    • Lesley R., Xu Y., Kalled S. L., et al.: Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 20: 441–453, 2004.
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1    Xu, Y.2    Kalled, S.L.3
  • 45
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.
    • Thien M., Phan T. G., Gardam S., et al.: Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 20: 785–798, 2004.
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3
  • 46
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.
    • Cheema G. S., Roschke V., Hilbert D. M., et al.: Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44: 1313–1319, 2001.
    • (2001) Arthritis Rheum , vol.44 , pp. 1313-1319
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3
  • 47
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus.
    • Zhang J., Roschke V., Baker K. P., et al.: Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 166: 6–10, 2001.
    • (2001) J Immunol , vol.166 , pp. 6-10
    • Zhang, J.1    Roschke, V.2    Baker, K.P.3
  • 48
    • 10744224617 scopus 로고    scopus 로고
    • B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations.
    • Stohl W., Metyas S., Tan S. M., et al.: B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum 48: 3475–3486, 2003.
    • (2003) Arthritis Rheum , vol.48 , pp. 3475-3486
    • Stohl, W.1    Metyas, S.2    Tan, S.M.3
  • 49
    • 2942750585 scopus 로고    scopus 로고
    • Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus.
    • Stohl W., Metyas S., Tan S. M., et al.: Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus. Ann Rheum Dis 63: 1096–1103, 2004.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1096-1103
    • Stohl, W.1    Metyas, S.2    Tan, S.M.3
  • 50
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome.
    • Groom J., Kalled S. L., Cutler A. H., et al.: Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 109: 59–68, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 59-68
    • Groom, J.1    Kalled, S.L.2    Cutler, A.H.3
  • 51
    • 0037310430 scopus 로고    scopus 로고
    • The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome.
    • Mariette X., Roux S., Zhang J., et al.: The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome. Ann Rheum Dis 62: 168–171, 2003.
    • (2003) Ann Rheum Dis , vol.62 , pp. 168-171
    • Mariette, X.1    Roux, S.2    Zhang, J.3
  • 52
    • 23644454110 scopus 로고    scopus 로고
    • Is periodontal disease mediated by salivary baff in sjogren's syndrome?
    • Pers J. O., d'Arbonneau F., Devauchelle-Pensec V., et al.: Is periodontal disease mediated by salivary baff in sjogren's syndrome? Arthritis Rheum 52: 2411–2414, 2005.
    • (2005) Arthritis Rheum , vol.52 , pp. 2411-2414
    • Pers, J.O.1    d'Arbonneau, F.2    Devauchelle-Pensec, V.3
  • 53
    • 0034918211 scopus 로고    scopus 로고
    • TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice.
    • Wang H., Marsters S. A., Baker T., et al.: TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice. Nat Immunol 2: 632–637, 2001.
    • (2001) Nat Immunol , vol.2 , pp. 632-637
    • Wang, H.1    Marsters, S.A.2    Baker, T.3
  • 54
    • 5144223503 scopus 로고    scopus 로고
    • Altered B lymphocyte function induces systemic autoimmunity in systemic sclerosis.
    • Sato S., Fujimoto M., Hasegawa M., et al.: Altered B lymphocyte function induces systemic autoimmunity in systemic sclerosis. Mol Immunol 41: 1123–1133, 2004.
    • (2004) Mol Immunol , vol.41 , pp. 1123-1133
    • Sato, S.1    Fujimoto, M.2    Hasegawa, M.3
  • 55
    • 85024752599 scopus 로고    scopus 로고
    • Elevated Serum BAFF Levels in Patients with Systemic Sclerosis (SSc): Enhanced BAFF Signaling in SSc B Lymphocytes
    • Matsushita T., Hasegawa M., Yanaba K., et al.: Elevated Serum BAFF Levels in Patients with Systemic Sclerosis (SSc): Enhanced BAFF Signaling in SSc B Lymphocytes. Arthritis Rheum: in press.
    • Arthritis Rheum: in press.
    • Matsushita, T.1    Hasegawa, M.2    Yanaba, K.3
  • 56
    • 0036262665 scopus 로고    scopus 로고
    • CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
    • Saito E., Fujimoto M., Hasegawa M., et al.: CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse. J Clin Invest 109: 1453–1462, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 1453-1462
    • Saito, E.1    Fujimoto, M.2    Hasegawa, M.3
  • 57
    • 20244384231 scopus 로고    scopus 로고
    • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma.
    • Krumbholz M., Theil D., Derfuss T., et al.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 201: 195–200, 2005.
    • (2005) J Exp Med , vol.201 , pp. 195-200
    • Krumbholz, M.1    Theil, D.2    Derfuss, T.3
  • 58
    • 1242340285 scopus 로고    scopus 로고
    • Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.
    • Magliozzi R., Columba-Cabezas S., Serafini B., et al.: Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. J Neuroimmunol 148: 11–23, 2004.
    • (2004) J Neuroimmunol , vol.148 , pp. 11-23
    • Magliozzi, R.1    Columba-Cabezas, S.2    Serafini, B.3
  • 59
    • 16244423682 scopus 로고    scopus 로고
    • The role of BAFF in immune function and implications for autoimmunity.
    • Kalled S.L.: The role of BAFF in immune function and implications for autoimmunity. Immunol Rev 204: 43–54, 2005.
    • (2005) Immunol Rev , vol.204 , pp. 43-54
    • Kalled, S.L.1
  • 60
    • 12344297875 scopus 로고    scopus 로고
    • TACI and BAFF-R mediate isotype switching in B cells.
    • Castigli E., Wilson S. A., Scott S., et al.: TACI and BAFF-R mediate isotype switching in B cells. J Exp Med 201: 35–39, 2005.
    • (2005) J Exp Med , vol.201 , pp. 35-39
    • Castigli, E.1    Wilson, S.A.2    Scott, S.3
  • 61
    • 23044443492 scopus 로고    scopus 로고
    • Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.
    • Salzer U., Chapel H. M., Webster A. D., et al.: Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat Genet 37: 820–828, 2005.
    • (2005) Nat Genet , vol.37 , pp. 820-828
    • Salzer, U.1    Chapel, H.M.2    Webster, A.D.3
  • 62
    • 0242495115 scopus 로고    scopus 로고
    • Generation and characterization of Lym-phoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.
    • Baker K. P., Edwards B. M., Main S. H., et al.: Generation and characterization of Lym-phoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator. Arthritis Rheum 48: 3253–3265, 2003.
    • (2003) Arthritis Rheum , vol.48 , pp. 3253-3265
    • Baker, K.P.1    Edwards, B.M.2    Main, S.H.3
  • 63
    • 0346026830 scopus 로고    scopus 로고
    • Safety, pharmacokinetic and pharmacodynamic results of a phase 1 single and double dose-escalation study of LymphoStat-B (human monoclonal antibody to BLyS) in SLE patients
    • (Suppl.)
    • Furie R., Stohl W., Ginzler E., et al.: Safety, pharmacokinetic and pharmacodynamic results of a phase 1 single and double dose-escalation study of LymphoStat-B (human monoclonal antibody to BLyS) in SLE patients. Arthritis Rheum 48 (Suppl.): S377, 2003.
    • (2003) Arthritis Rheum , vol.48 , pp. S377
    • Furie, R.1    Stohl, W.2    Ginzler, E.3
  • 64
    • 16544361842 scopus 로고    scopus 로고
    • BlySfulness does not equal blissfulness in systemic lupus erythematosus: a therapeutic role for BLyS antagonists
    • Stohl W: BlySfulness does not equal blissfulness in systemic lupus erythematosus: a therapeutic role for BLyS antagonists. Curr Dir Autoimmun 8:289–304, 2005.
    • (2005) Curr Dir Autoimmun , vol.8 , pp. 289-304
    • Stohl, W.1


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