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Volumn 14, Issue 6, 2005, Pages 1481-1485

Exploration of genetic alterations in human endometrial cancer and melanoma: Distinct tumorigenic pathways that share a frequent abnormal PI3K/AKT cascade

Author keywords

Endometrial cancer; Melanoma; Mutation; P13K AKT cascade; PTEN; RAF; RAS

Indexed keywords

A RAF KINASE; B RAF KINASE; BRAF PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS PROTEIN;

EID: 33644665451     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.14.6.1481     Document Type: Article
Times cited : (20)

References (27)
  • 1
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I and Sawyers CL: The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501, 2002. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 2
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J: Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3: 11-22, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 6
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • DOI 10.1074/jbc.273.22.13375
    • Maehama T and Dixon JE: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378, 1998. (Pubitemid 28268370)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.22 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 9
  • 10
    • 0030911052 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
    • DOI 10.1016/S0092-8674(00)80226-3
    • Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A and Downward J: Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 89: 457-467, 1997. (Pubitemid 27220890)
    • (1997) Cell , vol.89 , Issue.3 , pp. 457-467
    • Rodriguez-Viciana, P.1    Warne, P.H.2    Khwaja, A.3    Marte, B.M.4    Pappin, D.5    Das, P.6    Waterfield, M.D.7    Ridley, A.8    Downward, J.9
  • 12
    • 1542510675 scopus 로고    scopus 로고
    • B-Raf Is Dispensable for K-Ras-Mediated Oncogenesis in Human Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-3862
    • Kim JS, Lee C, Foxworth A and Waldman T: B-Raf is dispensable for K-Ras-mediated oncogenesis in human cancer cells. Cancer Res 64: 1932-1937, 2004. (Pubitemid 38339436)
    • (2004) Cancer Research , vol.64 , Issue.6 , pp. 1932-1937
    • Kim, J.-S.1    Lee, C.2    Foxworth, A.3    Waldman, T.4
  • 14
    • 0034185044 scopus 로고    scopus 로고
    • Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer
    • Ikeda T, Yoshinaga K, Suzuki A, Sakurada A, Ohmori H and Horii A: Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer. Oncol Rep 7: 567-570, 2000.
    • (2000) Oncol Rep , vol.7 , pp. 567-570
    • Ikeda, T.1    Yoshinaga, K.2    Suzuki, A.3    Sakurada, A.4    Ohmori, H.5    Horii, A.6
  • 15
    • 3543056881 scopus 로고    scopus 로고
    • Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression
    • DOI 10.1101/gad.1213804
    • Mao JH, To MD, Perez-Losada J, Wu D, Del Rosario R and Balmain A: Mutually exclusive mutations of the PTEN and ras pathways in skin tumor progression. Genes Dev 18: 1800-1805, 2004. (Pubitemid 39025090)
    • (2004) Genes and Development , vol.18 , Issue.15 , pp. 1800-1805
    • Mao, J.-H.1    To, M.D.2    Perez-Losada, J.3    Wu, D.4    Del, R.R.5    Balmain, A.6
  • 16
    • 1442274619 scopus 로고    scopus 로고
    • Genetic Interaction between NRAS and BRAF Mutations and PTEN/MMAC1 Inactivation in Melanoma
    • DOI 10.1046/j.0022-202X.2004.22243.x
    • Tsao H, Goel V, Wu H, Yang G and Haluska FG: Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol 122: 337-341, 2004. (Pubitemid 38281053)
    • (2004) Journal of Investigative Dermatology , vol.122 , Issue.2 , pp. 337-341
    • Tsao, H.1    Goel, V.2    Wu, H.3    Yang, G.4    Haluska, F.G.5
  • 17
    • 0029854322 scopus 로고    scopus 로고
    • Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a I-cM region of common allelic loss
    • DOI 10.1002/(SICI)1098-2264(199610)17:2<88::AID
    • Kimura M, Abe T, Sunamura M, Matsuno S and Horii A: Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a 1-cM region of common allelic loss. Genes Chromosomes Cancer 17: 88-93, 1996. (Pubitemid 26395526)
    • (1996) Genes Chromosomes and Cancer , vol.17 , Issue.2 , pp. 88-93
    • Kimura, M.1    Abe, T.2    Sunamura, M.3    Matsuno, S.4    Horii, A.5
  • 20
    • 1342299898 scopus 로고    scopus 로고
    • Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas
    • DOI 10.1093/carcin/bgh049
    • Fransen K, Klintenas M, Osterstrom A, Dimberg J, Monstein HJ and Söderkvist P: Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas. Carcinogenesis 25: 527-533, 2004. (Pubitemid 38528645)
    • (2004) Carcinogenesis , vol.25 , Issue.4 , pp. 527-533
    • Fransen, K.1    Klintenas, M.2    Osterstrom, A.3    Dimberg, J.4    Monstein, H.-J.5    Soderkvist, P.6
  • 21
    • 0032960108 scopus 로고    scopus 로고
    • The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair protein
    • Kondo E, Horii A and Fukushige S: The human PMS2L proteins do not interact with hMLHl, a major DNA mismatch repair protein. J Biochem 125: 818-825, 1999. (Pubitemid 29192505)
    • (1999) Journal of Biochemistry , vol.125 , Issue.4 , pp. 818-825
    • Kondo, E.1    Horii, A.2    Fukushige, S.3
  • 22
    • 0034085811 scopus 로고    scopus 로고
    • Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines
    • Tsao H, Zhang X, Fowlkes K and Haluska FG: Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines. Cancer Res 60: 1800-1804, 2000. (Pubitemid 30207633)
    • (2000) Cancer Research , vol.60 , Issue.7 , pp. 1800-1804
    • Tsao, H.1    Zhang, X.2    Fowlkes, K.3    Haluska, F.G.4
  • 24
    • 0034096201 scopus 로고    scopus 로고
    • Protein phosphatases and the regulation of mitogen-activated protein kinase signalling
    • Keyse SM: Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr Opin Cell Biol 12: 186-192, 2000.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 186-192
    • Keyse, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.