Comparative studies on mucosal and intravenous transmission of simian immunodeficiency virus (SIVsm): Evolution of coreceptor use varies with pathogenic outcome

Journal of General Virology

Volumn 87, Issue 3, 2006, Pages 581-594

  Laurén, Anna ^a   Vödrös, Dalma ^a,b,d   Thorstensson, Rigmor ^c   Fenyö, Eva Maria ^a  

^a LUND UNIVERSITY   (Sweden)

^b NATIONAL CENTER FOR EPIDEMIOLOGY   (Hungary)

^c SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^d EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR6; ORPHAN RECEPTOR GPR15; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

ACUTE DISEASE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CD4 LYMPHOCYTE COUNT; CERCOCEBUS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL INFECTION; HOMOSEXUALITY; HUMAN; HUMAN CELL; INOCULATION; INTRAVENOUS DRUG ABUSE; MACACA; MOLECULAR EVOLUTION; MONKEY DISEASE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECEPTOR BINDING; RECTUM MUCOSA; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CELL INTERACTION; VIRUS ISOLATION; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS TRANSMISSION; VIRUS VIRULENCE;

ANIMALS; CELL LINE; CERCOCEBUS ATYS; DISEASE PROGRESSION; DISEASE TRANSMISSION, HORIZONTAL; EVOLUTION, MOLECULAR; HUMANS; LEUKOCYTES, MONONUCLEAR; MACACA FASCICULARIS; RECEPTORS, CCR5; RECEPTORS, CXCR4; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RECEPTORS, VIRUS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRULENCE; VIRUS REPLICATION;

ANIMALIA; CERCOCEBUS; CERCOCEBUS TORQUATUS ATYS; MACACA; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 33644607571     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81408-0     Document Type: Article

References (59)

1. Alkhatib, G., Liao, F., Berger, E. A., Farber, J. M. & Peden, K. W. C. (1997). A new SIV co-receptor, STRL33. Nature 388, 238.
2. Antonsson, L., Boketoft, A., Garzino-Demo, A., Olde, B. & Owman, C. (2003). Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4. AIDS 17, 2571-2579.
3. Björndal, Å., Deng, H., Jansson, M. & 7 other authors (1997). Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype. J Virol 71, 7478-7487.
4. Bleul, C. C., Wu, L., Hoxie, J. A., Springer, T. A. & Mackay, C. R. (1997). The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A 94, 1925-1930.
5. Brelot, A., Heveker, N., Pleskoff, O., Sol, N. & Alizon, M. (1997). Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity. J Virol 71, 4744-4751.
6. Chen, Z., Zhou, P., Ho, D. D., Landau, N. R. & Marx, P. A. (1997). Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry. J Virol 71, 2705-2714.
7. Cilliers, T., Nhlapo, J., Coetzer, M., Orlovic, D., Ketas, T., Olson, W. C., Moore, J. P., Trkola, A. & Morris, L. (2003). The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C. J Virol 77, 4449-4456.
8. Clapham, P. R. & McKnight, Á. (2002). Cell surface receptors, virus entry and tropism of primate lentiviruses. J Gen Virol 83, 1809-1829.
9. Deng, H., Liu, R., Ellmeier, W. & 12 other authors (1996). Identification of a major co-receptor for primary isolates of HIV-1. Nature 381, 661-666.
10. Deng, H. K., Unutmaz, D., KewalRamani, V. N. & Littman, D. R. (1997). Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 388, 296-300.
11. Doranz, B. J., Orsini, M. J., Turner, J. D., Hoffman, T. L., Berson, J. F., Hoxie, J. A., Peiper, S. C., Brass, L. F. & Doms, R. W. (1999). Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. J Virol 73, 2752-2761.
12. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381, 667-673.
13. Edinger, A. L., Amedee, A., Miller, K. & 11 other authors (1997). Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains. Proc Natl Acad Sci U S A 94, 4005-4010.
14. Eskild, A., Magnus, P., Brekke, T. & 7 other authors (1997). The impact of exposure group on the progression rate to acquired immunodeficiency syndrome. A comparison between intravenous drug users, homosexual men and heterosexually infected subjects. Scand J Infect Dis 29, 103-109.
15. Farzan, M., Choe, H., Martin, K. & 10 other authors (1997). Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J Exp Med 186, 405-411.
16. Feng, Y., Broder, C. C., Kennedy, P. E. & Berger, E. A. (1996). HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272, 872-877.
17. Forte, S., Harmon, M.-E., Pineda, M. J. & Overbaugh, J. (2003). Early- and intermediate-stage variants of simian immunodeficiency virus replicate efficiently in cells lacking CCR5. J Virol 77, 9723-9727.
18. Fultz, P. N., McClure, H. M., Anderson, D. C., Swenson, R. B., Anand, R. & Srinivasan, A. (1986). Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys). Proc Natl Acad Sci U S A 83, 5286-5290.
19. Gerlach, L. O., Skerlj, R. T., Bridger, G. J. & Schwartz, T. W. (2001). Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor. J Biol Chem 276, 14153-14160.
20. 262 of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100. Mol Pharmacol 60, 164-173.
21. Hengge, U. R., Franz, B., Hoersch, S. & Goos, M. (2003). Course of HIV disease does not depend on risk group: 7.5-year follow-up in 296 patients. Int J STD AIDS 14, 451-457.
22. Hirsch, V. M., Edmondson, P., Murphey-Corb, M., Arbeille, B., Johnson, P. R. & Mullins, J. I. (1989). SIV adaptation to human cells. Nature 341, 573-574.
23. SM PBj: evidence of macrophage-dependent viral amplification. Nat Med 4, 1401-1408.
24. Karlsson, A., Parsmyr, K., Sandström, E., Fenyö, E. M. & Albert, J. (1994). MT-2 cell tropism as prognostic marker for disease progression in human immunodeficiency virus type 1 infection. J Clin Microbiol 32, 364-370.
25. Karlsson, I., Antonsson, L., Shi, Y., Karlsson, A., Albert, J., Leitner, T., Olde, B., Owman, C. & Fenyö, E. M. (2003). HIV biological variability unveiled: frequent isolations and chimeric receptors reveal unprecedented variation of coreceptor use. AIDS 17, 2561-2569.
26. Karlsson, I., Antonsson, L., Shi, Y. & 7 other authors (2004). Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype. J Virol 78, 11807-11815.
27. Kestler, H., Kodama, T., Ringler, D. & 8 other authors (1990). Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus. Science 248, 1109-1112.
28. Kimata, J. T., Gosink, J. J., KewalRamani, V. N., Rudensey, L. M., Littman, D. R. & Overbaugh, J. (1999a). Coreceptor specificity of temporal variants of simian immunodeficiency virus Mne. J Virol 73, 1655-1660.
29. Kimata, J. T., Kuller, L., Anderson, D. B., Dailey, P. & Overbaugh, J. (1999b). Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression. Nat Med 5, 535-541.
30. Labrosse, B., Brelot, A., Heveker, N., Sol, N., Schols, D., De Clercq, E. & Alizon, M. (1998). Determinants for sensitivity of human immunodeficiency virus coreceptor CXCR4 to the bicyclam AMD3100. J Virol 72, 6381-6388.
31. Laurén, A., Thorstensson, R. & Fenyö, E. M. (2006). Comparative studies on mucosal and intravenous transmission of simian immunodeficiency virus (SIVsm): the kinetics of evolution to neutralization resistance are related to progression rate of disease. J Gen Virol 87, 595-606.
32. Letvin, N. L., Daniel, M. D., Sehgal, P. K. & 7 other authors (1985). Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science 230, 71-73.
33. + T cells. Nature 434, 1148-1152.
34. Lu, Y., Brosio, P., Lafaile, M., Li, J., Collman, R. G., Sodroski, J. & Miller, C. J. (1996). Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques. J Virol 70, 3045-3050.
35. Mäkitalo, B., Böttiger, P., Biberfeld, G. & Thorstensson, R. (2000). Cell-mediated immunity to low doses of SIVsm in cynomolgus macaques did not confer protection against mucosal rechallenge. Vaccine 19, 298-307.
36. mac239. J Virol 71, 2522-2527.
37. Margulies, B. J., Hauer, D. A. & Clements, J. E. (2001). Identification and comparison of eleven rhesus macaque chemokine receptors. AIDS Res Hum Retroviruses 17, 981-986.
38. + T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097.
39. + cells. Nat Med 8, 150-156.
40. Mörner, A., Björndal, Å., Albert, J., KewalRamani, V. N., Littman, D. R., Inoue, R., Thorstensson, R., Fenyö, E. M. & Björling, E. (1999). Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage. J Virol 73, 2343-2349.
41. Nilsson, C., Thorstensson, R., Gilljam, G. & 7 other authors (1995). Protection against monkey-cell grown cell-free HIV-2 challenge in macaques immunized with native HIV-2 envelope glycoprotein gp125. Vaccine Res 4, 165-175.
42. Owen, S. M., Masciotra, S., Novembre, F., Yee, J., Switzer, W. M., Ostyula, M. & Lal, R. B. (2000). Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cells. J Virol 74, 5702-5708.
43. Pehrson, P., Lindback, S., Lidman, C., Gaines, H. & Giesecke, J. (1997). Longer survival after HIV infection for injecting drug users than for homosexual men: implications for immunology. AIDS 11, 1007-1012.
44. Pöhlmann, S., Stolte, N., Münch, J., Ten Haaft, P., Heeney, J. L., Stahl-Hennig, C. & Kirchhoff, F. (1999). Co-receptor usage of BOB/GPR15 in addition to CCR5 has no significant effect on replication of simian immunodeficiency virus in vivo. J Infect Dis 180, 1494-1502.
45. Prins, M. & Veugelers, P. J. (1997). Comparison of progression and non-progression in injecting drug users and homosexual men with documented dates of HIV-1 seroconversion. European Seroconverter Study and the Tricontinental Seroconverter Study. AIDS 11, 621-631.
46. Quesada-Rolander, M., Mäkitalo, B., Thorstensson, R., Zhang, Y.-J., Castaños-Velez, E., Biberfeld, G. & Putkonen, P. (1996). Protection against mucosal SIVsm challenge in macaques infected with a chimeric SIV that expresses HIV type 1 envelope. AIDS Res Hum Retroviruses 12, 993-999.
47. Rudensey, L. M., Kimata, J. T., Benveniste, R. E. & Overbaugh, J. (1995). Progression to AIDS in macaques is associated with changes in the replication, tropism, and cytopathic properties of the simian immunodeficiency virus variant population. Virology 207, 528-542.
48. Schols, D. & De Clercq, E. (1998). The simian immunodeficiency virus mnd(GB-1) strain uses CXCR4, not CCR5, as coreceptor for entry in human cells. J Gen Virol 79, 2203-2205.
49. Spijkerman, I. J., Koot, M., Prins, M., Keet, I. P., van den Hoek, A. J., Miedema, F. & Coutinho, R. A. (1995). Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men. AIDS 9, 1085-1092.
50. Stahl-Hennig, C., Steinman, R. M., Tenner-Racz, K. & 7 other authors (1999). Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus. Science 285, 1261-1265.
51. Stalmeijer, E. H. B., van Rij, R. P., Boeser-Nunnink, B., Visser, J. A., Naarding, M. A., Schols, D. & Schuitemaker, H. (2004). In vivo evolution of X4 human immunodeficiency virus type 1 variants in the natural course of infection coincides with decreasing sensitivity to CXCR4 antagonists. J Virol 78, 2722-2728.
52. Ten Haaft, P., Verstrepen, B., Überla, K., Rosenwirth, B. & Heeney, J. (1998). A pathogenic threshold of virus load defined in simian immunodeficiency virus- or simian-human immunodeficiency virus-infected macaques. J Virol 72, 10281-10285.
53. Thorstensson, R., Walther, L., Putkonen, P., Albert, J. & Biberfeld, G. (1991). A capture enzyme immunoassay for detection of HIV-2/SIV antigen. J Acquir Immune Defic Syndr 4, 374-379.
54. + T cell depletion and viral replication in SIV infection. Science 280, 427-431.
55. Vödrös, D., Thorstensson, R., Biberfeld, G., Schols, D., De Clercq, E. & Fenyö, E. M. (2001a). Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally infected with simian immunodeficiency virus (SIVsm). Virology 291, 12-21.
56. Vödrös, D., Tscherning-Casper, C., Navea, L., Schols, D., De Clercq, E. & Fenyö, E. M. (2001b). Quantitative evaluation of HIV-1 coreceptor use in the GHOST(3) cell assay. Virology 291, 1-11.
57. Vödrös, D., Thorstensson, R., Doms, R. W., Fenyö, E. M. & Reeves, J. D. (2003). Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques. Virology 316, 17-28.
58. Zhang, L., He, T., Talal, A., Wang, G., Frankel, S. S. & Ho, D. D. (1998). In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5. J Virol 72, 5035-5045.
59. + T cells. Science 286, 1353-1357.