Protection against mucosal SIV(sm) challenge in macaques infected with a chimeric SIV that expresses HIV type 1 envelope

AIDS Research and Human Retroviruses

Volumn 12, Issue 11, 1996, Pages 993-999

  Quesada Rolander, Marlene ^a   Mäkitalo, Barbro ^a   Thorstensson, Rigmor ^a   Zhang, Yi Jun ^a   Castaños Velez, Esmeralda ^b   Biberfeld, Gunnel ^a   Putkonen, Per ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CROSS REACTING ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS ANTIGEN; VIRUS DNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL MODEL; ANTIBODY TITER; ANTIGEN DETECTION; ARTICLE; CHIMERA; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHESUS MONKEY; T LYMPHOCYTE SUBPOPULATION; VIRAL GENETICS; VIRUS CELL INTERACTION; VIRUS ENVELOPE; VIRUS REPLICATION; ANIMAL; ANTIBODY PRODUCTION; BLOOD TRANSFUSION; CD4 LYMPHOCYTE COUNT; CYTOTOXIC T LYMPHOCYTE; DISEASE MODEL; ENVELOPE GENE; GENETICS; IMMUNOLOGY; MACACA; MONKEY DISEASE; MUCOSAL IMMUNITY; SIMIAN IMMUNODEFICIENCY VIRUS; VIROLOGY;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ANTIBODY FORMATION; BLOOD TRANSFUSION; CD4 LYMPHOCYTE COUNT; CHIMERA; DISEASE MODELS, ANIMAL; GENES, ENV; HIV-1; IMMUNITY, MUCOSAL; MACACA FASCICULARIS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0029659042     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1996.12.993     Document Type: Article

References (27)

1. Alter HJ, Eichberg JW, Masur H, Saxinger WC, Gallo R, Macher AM, Lane HC, and Fauci AS: Transmission of HTLV-III infection from human plasma to chimpanzees: An animal model for AIDS. Science 1984;226:549-552.
2. Putkonen P, Böttiger B, Warstedt K, Thorstensson R, Albert J, and Biberfeld G: Experimental infection of cynomolgus monkeys (Macaca fascicularis) with HIV-2. J Acquir Immune Defic Syndr 1989;2:366-373.
3. Desrosiers RC: The simian immunodeficiency viruses. Annu Rev Immunol 1990;8:557-578.
4. sm) closely related to HIV-2. Nature (London) 1989;339:389-392.
5. Putkonen P, Kaaya E, Böttiger D, Li S-L, Nilsson C, Biberfeld P, and Biberfeld G: Clinical features and predictive markers of disease progression in cynomolgus monkeys experimentally infected with simian immunodeficiency virus. AIDS 1992;6:257-263.
6. Saag MS, Hahn BH, Gibbons J, Li Y, Parks ES, Parks WP, and Shaw GM: Extensive variation of human immunodeficiency virus type-1 in vivo. Nature (London) 1988;334:440-444.
7. Li J, Lord CI, Haseltine W, Letvin NL, and Sodroski J: Infection of cynomolgus monkeys with a chimeric HIV-1/SIV virus that expresses the HIV-1 envelope glycoproteins. J Acquir Immune Defic Syndr 1992;5:639-646.
8. Sakuragi S, Shibata R, Mukai R, Komatsu T, Fukasawa M, Sakai H, Sakuragi J-I, Kawamura M, Ibuki K, Hayami M, and Adachi A: Infection of macaque monkeys with a chimeric human and simian immunodeficiency virus. J Gen Virol 1992;73:2983-2987.
9. Fultz PN, McClure H, Andersson DC, Swenson RB, Anand R, and Srinivasan A: Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys). Proc Natl Acad Sci USA 1986;83:5286-5290.
10. Nilsson C, Thorstensson R, Gilljam G, Sjölander S, Hild K, Broliden K, Åkerblom L, Morein B, Biberfeld G, and Putkonen P: Protection against monkey-cell grown cell-free HIV-2 challenge in macaques immunized with native HIV-2 envelope glycoprotein. Vaccine Res 1995;4:165-175.
11. Thorstensson R, Walther L, Putkonen P, Albert J, and Biberfeld G: A capture immunoassay for detection of HIV-2/SIV antigen. J Acquir Immune Defic Syndr 1991;4:374-379.
12. Grankvist O, Bredberg-Rådén U, Gustafsson Å, Albert J, Albino P, Andreasson PÅ, Nauclér A, Biberfeld G, and Wadell G: Improved detection of HIV-2 DNA in clinical samples using a nested primer-based polymerase chain reaction. J Acquir Immune Defic Syndr 1992;5:286-293.
13. Bredberg-Rådén U, Urassa E, Grankvist O, Massawe A, Lyamuya E, Kawo G, Msemo G, Kazimoto T, Mgone J, Mbena E, Karlsson K, Mhalu F, and Biberfeld G: Early diagnosis of HIV-1 infection in infants in Dar es Salaam, Tanzania. Clin Diag Virol 1995;4:163-173.
14. mac). AIDS 1988;2:195-199.
15. SBL-6669 in nonpathogenic infection of macaques. Virology 1994;200:583-589.
16. Andersson S, Mäkitalo B, Thorstensson R, Franchini G, Tartaglia J, Limbach K, Paoletti E, Putkonen P, and Biberfeld G: Immunogenicity and protective efficacy of an HIV-2 recombinant canarypox (ALVAC) vaccine candidate in cynomolgus monkeys. Submitted (1996).
17. Pantaleo G, Menzo S, Vaccarezza M, Graziosi C, Cohen OJ, Demarest JF, Montefiori D, Orenstein JM, Fox C, Schrager LK, Margolick JB, Buchbinder S, Giorgi JV, and Fauci AS: Studies in subjects with long-term nohprogressive human immunodeficiency virus infection. N Engl J Med 1995;332:209-216.
18. Putkonen P, Walther L, Zhang Y-J, Nilsson C, Albert J, Biberfeld P, Thorstensson R, and Biberfeld G: Long-term protection against SIV-induced disease in macaques vaccinated with a live attenuated HIV-2 vaccine. Nature Med 1995;1:914-918.
19. Almond N, Kent K, Cranage M, Rud E, Clarke B, and Stott EJ: Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus infected cells. Lancet 1995;345:1342-1344.
20. Letvin N, Li J, Halloran M, Cranage M, Rud EW, and Sodroski J: Prior infection with a nonpathogenic simian human immunodeficency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus. J Virol 1995;69:4569-4571.
21. Berman PW, Gregory TJ, Riddle L, Nakamura GR, Champe MA, Porter JP, Wurm FM, Herschberg RD, Cobb EK, and Eichberg JW: Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160. Nature (London) 1990;345:622-625.
22. Tabor E and Gerety RJ: Possible role of immune responses to hepatitis B core antigen in protection against hepatitis B infections. Lancet 1984;1:172.
23. Taylor PM and Askonas BA: Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo. Immunology 1986;58: 417-420.
24. Gotch F, Gallimore A, McAdam S, and McMichael A: Cytotoxic T lymphocyte epitopes shared between HIV-1, HIV-2, and SIV. J Med Primatol 1993;22:119-123.
25. Ho DD, Samgadharan M, Hirsch M, Scooley RT, Rota TR, Kennedy RC, Chanh TC, and Sato VL: Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins. J Virol 1987;61:2024-2028.
26. Walker CM, Moody DJ, Stites DP, and Levy JA: CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 1986;234:1563-1566.
27. Gallimore A, Cranage M, Cook N, Almond N, Bootman J, Rud E, Silvera P, Dennis M, Corcoran T, Stott J, McMichael A, and Gotch F: Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques. Nature Med 1995;1:1167-1173.