-
1
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
-
Adams M, Reginato MJ, Shao D, Lazar MA, and Chatterjee VK (1997) Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem 272:5128-5132.
-
(1997)
J Biol Chem
, vol.272
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
2
-
-
0036140937
-
Diclofenac antagonizes peroxisome proliferator-activated receptor-γ signaling
-
Adamson DJ, Frew D, Tatoud R, Wolf CR, and Palmer CAN (2002) Diclofenac antagonizes peroxisome proliferator-activated receptor-γ signaling. Mol Pharmacol 61:7-12.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 7-12
-
-
Adamson, D.J.1
Frew, D.2
Tatoud, R.3
Wolf, C.R.4
Palmer, C.A.N.5
-
3
-
-
0036260962
-
Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): Inhibition of cyclooxygenase and induction of NSAID-activated gene
-
Baek SJ, Wilson LC, Lee C-H, and Eling TE (2002) Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene. J Pharmacol Exp Ther 301:1126-1131.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 1126-1131
-
-
Baek, S.J.1
Wilson, L.C.2
Lee, C.-H.3
Eling, T.E.4
-
4
-
-
0031595670
-
Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells
-
Brockman JA, Gupta RA, and DuBois RN (1998) Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 115:1049-1055.
-
(1998)
Gastroenterology
, vol.115
, pp. 1049-1055
-
-
Brockman, J.A.1
Gupta, R.A.2
DuBois, R.N.3
-
5
-
-
0035033709
-
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation
-
Brown WA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, and O'Brien PE (2001) Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation. Gut 48:660-666.
-
(2001)
Gut
, vol.48
, pp. 660-666
-
-
Brown, W.A.1
Skinner, S.A.2
Malcontenti-Wilson, C.3
Vogiagis, D.4
O'Brien, P.E.5
-
6
-
-
0036796142
-
Analysis of cyclooxygenase expression in human colorectal adenomas
-
Chapple KS, Scott N, Guillou PJ, Coletta PL, and Hull MA (2002) Analysis of cyclooxygenase expression in human colorectal adenomas. Dis Colon Rectum 45:1316-1324.
-
(2002)
Dis Colon Rectum
, vol.45
, pp. 1316-1324
-
-
Chapple, K.S.1
Scott, N.2
Guillou, P.J.3
Coletta, P.L.4
Hull, M.A.5
-
8
-
-
0034282465
-
Genetic disruption of Ptgs.1, as well as of Ptgs.2, reduces intestinal tumorigenesis in Min mice
-
Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG, Smithies O, and Langenbach R (2000) Genetic disruption of Ptgs.1, as well as of Ptgs.2, reduces intestinal tumorigenesis in Min mice. Cancer Res 60:4705-4708.
-
(2000)
Cancer Res
, vol.60
, pp. 4705-4708
-
-
Chulada, P.C.1
Thompson, M.B.2
Mahler, J.F.3
Doyle, C.M.4
Gaul, B.W.5
Lee, C.6
Tiano, H.F.7
Morham, S.G.8
Smithies, O.9
Langenbach, R.10
-
9
-
-
0035252741
-
The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β-catertin/TCF-4 signaling
-
Dihlmann S, Siermann A, and von Knebel Doeberitz M (2001) The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β-catertin/TCF-4 signaling. Oncogene 20:645-653.
-
(2001)
Oncogene
, vol.20
, pp. 645-653
-
-
Dihlmann, S.1
Siermann, A.2
Von Knebel Doeberitz, M.3
-
11
-
-
0035183413
-
Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs
-
Garcia Rodriguez LA and Huerta-Alvarez C (2001) Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs. Epidemiology 12:88-93.
-
(2001)
Epidemiology
, vol.12
, pp. 88-93
-
-
Garcia Rodriguez, L.A.1
Huerta-Alvarez, C.2
-
12
-
-
0037109043
-
APC-dependent suppression of colon carcinogenesis by PPARγ
-
Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, et al. (2002) APC-dependent suppression of colon carcinogenesis by PPARγ. Proc Natl Acad Sci USA 99:13771-13776.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13771-13776
-
-
Girnun, G.D.1
Smith, W.M.2
Drori, S.3
Sarraf, P.4
Mueller, E.5
Eng, C.6
Nambiar, P.7
Rosenberg, D.W.8
Bronson, R.T.9
Edelmann, W.10
-
13
-
-
0035496616
-
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
-
Gupta RA and DuBois RN (2001) Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Cancer Rev 1:11-21.
-
(2001)
Nat Cancer Rev
, vol.1
, pp. 11-21
-
-
Gupta, R.A.1
DuBois, R.N.2
-
15
-
-
0034007387
-
A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis
-
Gurnell M, Wentworth JM, Agostini M, Adams M, Collingwood TN, Provenzano C, Browne PO, Rajanayagam O, Burris TP, Schwabe JW, et al. (2000) A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis. J Biol Chem 275:5754-5759.
-
(2000)
J Biol Chem
, vol.275
, pp. 5754-5759
-
-
Gurnell, M.1
Wentworth, J.M.2
Agostini, M.3
Adams, M.4
Collingwood, T.N.5
Provenzano, C.6
Browne, P.O.7
Rajanayagam, O.8
Burris, T.P.9
Schwabe, J.W.10
-
16
-
-
0036199569
-
Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor target genes in human colorectal cancer cells
-
Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, and Hull MA (2002) Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis 23:107-114.
-
(2002)
Carcinogenesis
, vol.23
, pp. 107-114
-
-
Hawcroft, G.1
D'Amico, M.2
Albanese, C.3
Markham, A.F.4
Pestell, R.G.5
Hull, M.A.6
-
17
-
-
0029760238
-
Effect of indomethacin suppositories on rectal polyposis in patients with familial adenomatous polyposis
-
Hirota C, Lida M, Aoyagi K, Matsumoto T, Tada S, Yao T, and Fujishima M (1996) Effect of indomethacin suppositories on rectal polyposis in patients with familial adenomatous polyposis. Cancer 78:1660-1665.
-
(1996)
Cancer
, vol.78
, pp. 1660-1665
-
-
Hirota, C.1
Lida, M.2
Aoyagi, K.3
Matsumoto, T.4
Tada, S.5
Yao, T.6
Fujishima, M.7
-
18
-
-
0028335192
-
Anti-proliferative effect of nonsteroidal anti-inflammatory drugs against human colon cancer cells
-
Hixson LJ, Alberts DS, Krutzsch M, Einsphar J, Brendel K, Gross PH, Shipp Paranka N, Baier M, Emerson S, Pamukcu R, et al. (1994) Anti-proliferative effect of nonsteroidal anti-inflammatory drugs against human colon cancer cells. Cancer Epidemiol Biomarkers Prev 3:433-438.
-
(1994)
Cancer Epidemiol Biomarkers Prev
, vol.3
, pp. 433-438
-
-
Hixson, L.J.1
Alberts, D.S.2
Krutzsch, M.3
Einsphar, J.4
Brendel, K.5
Gross, P.H.6
Shipp Paranka, N.7
Baier, M.8
Emerson, S.9
Pamukcu, R.10
-
19
-
-
0001317511
-
Studies on the absorption, distribution and excretion of indomethacin in various species
-
Hucker HB, Zacchei AG, Cox SV, Brodie DA, and Cantwell NHR (1966) Studies on the absorption, distribution and excretion of indomethacin in various species. J Pharmacol Exp Ther 153:237-249.
-
(1966)
J Pharmacol Exp Ther
, vol.153
, pp. 237-249
-
-
Hucker, H.B.1
Zacchei, A.G.2
Cox, S.V.3
Brodie, D.A.4
Cantwell, N.H.R.5
-
20
-
-
0035894284
-
2 synthases by ibuprofen, naproxen and indomethacin
-
2 synthases by ibuprofen, naproxen and indomethacin. Biochem Pharmacol 62:1587-1595.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1587-1595
-
-
Jaradat, M.S.1
Wongsud, B.2
Phornchirasilp, S.3
Rangwala, S.M.4
Shams, G.5
Sutton, M.6
Romstedt, K.J.7
Noonan, D.J.8
Feller, D.R.9
-
21
-
-
0033915552
-
Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells
-
Kang H-J, Song M-J, Choung SY, Kim SJ, and Lee M-O (2000) Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells. Biol Pharm Bull 23:815-819.
-
(2000)
Biol Pharm Bull
, vol.23
, pp. 815-819
-
-
Kang, H.-J.1
Song, M.-J.2
Choung, S.Y.3
Kim, S.J.4
Lee, M.-O.5
-
22
-
-
0036235241
-
Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue
-
Kim K-S, Baek SJ, Flake GP, Loftin CD, Calvo BF, and Eling TE (2002) Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue. Gastroenterology 122:1388-1398.
-
(2002)
Gastroenterology
, vol.122
, pp. 1388-1398
-
-
Kim, K.-S.1
Baek, S.J.2
Flake, G.P.3
Loftin, C.D.4
Calvo, B.F.5
Eling, T.E.6
-
23
-
-
0034955201
-
Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells
-
Kim TI, Jin SH, Kim WH, Kang EH, Choi KY, Kim HJ, Shin SK, and Kang JK (2001) Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells. Int J Colorectal Dis 16:167-173.
-
(2001)
Int J Colorectal Dis
, vol.16
, pp. 167-173
-
-
Kim, T.I.1
Jin, S.H.2
Kim, W.H.3
Kang, E.H.4
Choi, K.Y.5
Kim, H.J.6
Shin, S.K.7
Kang, J.K.8
-
24
-
-
0034974007
-
The analysis of nonsteroidal anti-inflammatory drug selectivity in prostaglandin G/H synthase (PGHS)-null cells
-
Kirtikara K, Swangkul S, and Ballou LR (2001) The analysis of nonsteroidal anti-inflammatory drug selectivity in prostaglandin G/H synthase (PGHS)-null cells. Inflamm Res 50:327-332.
-
(2001)
Inflamm Res
, vol.50
, pp. 327-332
-
-
Kirtikara, K.1
Swangkul, S.2
Ballou, L.R.3
-
25
-
-
0033563675
-
Nonsteroidal anti-inflammatory drugs attenuate epidermal growth factor-induced proliferation independent of prostaglandin synthesis inhibition
-
Kokoska ER, Smith GS, Wolff AB, Deshpande Y, and Millet TA (1999) Nonsteroidal anti-inflammatory drugs attenuate epidermal growth factor-induced proliferation independent of prostaglandin synthesis inhibition. J Surg Res 84:186-192.
-
(1999)
J Surg Res
, vol.84
, pp. 186-192
-
-
Kokoska, E.R.1
Smith, G.S.2
Wolff, A.B.3
Deshpande, Y.4
Millet, T.A.5
-
26
-
-
0017210803
-
Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man
-
Kwan KC, Breault GO, Umbenhauer ER, McMahon FG, and Duggan DE (1976) Kinetics of indomethacin absorption, elimination and enterohepatic circulation in man. J Pharmacokinet Biopharm 4:255-280.
-
(1976)
J Pharmacokinet Biopharm
, vol.4
, pp. 255-280
-
-
Kwan, K.C.1
Breault, G.O.2
Umbenhauer, E.R.3
McMahon, F.G.4
Duggan, D.E.5
-
27
-
-
0031013395
-
Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, and Kliewer SA (1997) Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 272:3406-3410.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
28
-
-
0035951493
-
Anti-inflammatories inhibit cancer growth - But how?
-
Marx J (2001) Anti-inflammatories inhibit cancer growth - but how? Science (Wash DC) 291:581-582.
-
(2001)
Science (Wash DC)
, vol.291
, pp. 581-582
-
-
Marx, J.1
-
29
-
-
0033152206
-
Loss-of-function mutations in PPARγ associated with human colon cancer
-
Sarraf P, Mueller E, Smith WM, Wright HM, Kum JB, Aaltonen LA, de la Chapelle A, Spiegelman BM, and Eng C (1999) Loss-of-function mutations in PPARγ associated with human colon cancer. Mol Cell 3:799-804.
-
(1999)
Mol Cell
, vol.3
, pp. 799-804
-
-
Sarraf, P.1
Mueller, E.2
Smith, W.M.3
Wright, H.M.4
Kum, J.B.5
Aaltonen, L.A.6
De la Chapelle, A.7
Spiegelman, B.M.8
Eng, C.9
-
30
-
-
0030813607
-
Nonsteroidal anti-inflammatory drugs and colorectal cancer: Evolving concepts of their chemopreventive actions
-
Shiff SJ and Rigas B (1997) Nonsteroidal anti-inflammatory drugs and colorectal cancer: evolving concepts of their chemopreventive actions. Gastroenterology 113:1992-1998.
-
(1997)
Gastroenterology
, vol.113
, pp. 1992-1998
-
-
Shiff, S.J.1
Rigas, B.2
-
31
-
-
0033575796
-
The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal anti-inflammatory drugs (NSAIDs)
-
Shiff SJ and Rigas B (1999) The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal anti-inflammatory drugs (NSAIDs). J Exp Med 190:445-450.
-
(1999)
J Exp Med
, vol.190
, pp. 445-450
-
-
Shiff, S.J.1
Rigas, B.2
-
32
-
-
0036117576
-
Characteristics of the peroxisome proliferator activated receptor γ (PPARγ) ligand induced apoptosis in colon cancer cells
-
Shimada T, Kojima K, Yoshiura K, Hirashi H, and Terano A (2002) Characteristics of the peroxisome proliferator activated receptor γ (PPARγ) ligand induced apoptosis in colon cancer cells. Gut 50:658-664.
-
(2002)
Gut
, vol.50
, pp. 658-664
-
-
Shimada, T.1
Kojima, K.2
Yoshiura, K.3
Hirashi, H.4
Terano, A.5
-
33
-
-
0034057928
-
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: Evidence of different mechanisms of action
-
Smith M-L, Hawcroff G, and Hull MA (2000) The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur J Cancer 36:664-674.
-
(2000)
Eur J Cancer
, vol.36
, pp. 664-674
-
-
Smith, M.-L.1
Hawcroff, G.2
Hull, M.A.3
-
34
-
-
0024451995
-
Antitumor activity of indomethacin in mice bearing advanced colon 26 carcinoma compared with those with early transplants
-
Tanaka Y, Tanaka T, and Ishitsuka H (1989) Antitumor activity of indomethacin in mice bearing advanced colon 26 carcinoma compared with those with early transplants. Cancer Res 49:5935-5939.
-
(1989)
Cancer Res
, vol.49
, pp. 5935-5939
-
-
Tanaka, Y.1
Tanaka, T.2
Ishitsuka, H.3
-
35
-
-
0034816925
-
Cyclooxygenase-independent actions of cyclooxygenase inhibitors
-
Tegeder I, Pfeilschifter J, and Geisslinger G (2001) Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J 15:2057-2072.
-
(2001)
FASEB J
, vol.15
, pp. 2057-2072
-
-
Tegeder, I.1
Pfeilschifter, J.2
Geisslinger, G.3
-
36
-
-
0035740372
-
Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells
-
Turchanowa L, Dauletbaev N, Milovic V, and Stein J (2001) Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells. Eur J Clin Investig 31:887-893.
-
(2001)
Eur J Clin Investig
, vol.31
, pp. 887-893
-
-
Turchanowa, L.1
Dauletbaev, N.2
Milovic, V.3
Stein, J.4
-
37
-
-
0035052916
-
Inhibition of cellular proliferation through IκB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1
-
Wang C, Fu M, D'Amico M, Albanese C, Zhou J-N, Brownlee M, Lisanti MP, Chatterjee VKK, Lazar MA, and Pestell RG (2001) Inhibition of cellular proliferation through IκB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1. Mol Cell Biol 21:3057-3070.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3057-3070
-
-
Wang, C.1
Fu, M.2
D'Amico, M.3
Albanese, C.4
Zhou, J.-N.5
Brownlee, M.6
Lisanti, M.P.7
Chatterjee, V.K.K.8
Lazar, M.A.9
Pestell, R.G.10
-
38
-
-
0036082592
-
Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor γ in rheumatoid synovial cells
-
Yamazaki R, Kusunoki N, Matsuzaki T, Hashimoto S, and Kawai S (2002) Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor γ in rheumatoid synovial cells. J Pharmacol Exp Ther 302:18-25.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 18-25
-
-
Yamazaki, R.1
Kusunoki, N.2
Matsuzaki, T.3
Hashimoto, S.4
Kawai, S.5
-
39
-
-
0034602188
-
Role of BAX in the apoptotic response to anticancer agents
-
Zhang L, Yu J, Ho Park B, Kinzler KW, and Vogelstein B (2000) Role of BAX in the apoptotic response to anticancer agents. Science (Wash DC) 290:989-992.
-
(2000)
Science (Wash DC)
, vol.290
, pp. 989-992
-
-
Zhang, L.1
Yu, J.2
Ho Park, B.3
Kinzler, K.W.4
Vogelstein, B.5
-
40
-
-
0033575760
-
Malignant transformation and antineoplastic actions of nonsteroidal anti-inflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
-
Zhang X, Morham SG, Langenbach R, and Young DA (1999) Malignant transformation and antineoplastic actions of nonsteroidal anti-inflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J Exp Med 190:451-459.
-
(1999)
J Exp Med
, vol.190
, pp. 451-459
-
-
Zhang, X.1
Morham, S.G.2
Langenbach, R.3
Young, D.A.4
|