Reovirus oncolysis: The Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 30, 2004, Pages 11099-11104

  Norman, Kara L ^a   Hirasawa, Kensuke ^a   Yang, An Dao ^a   Shields, Michael A ^a   Lee, Patrick W K ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Ras signaling pathway; Reovirus cancer therapy

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN RLF; RAF PROTEIN; RAL PROTEIN; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER THERAPY; CELL STRAIN 3T3; CELL TRANSFORMATION; CYTOLYSIS; MOUSE; MUTATION; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REOVIRUS; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION;

3T3 CELLS; ANIMALS; DNA, VIRAL; GTP PHOSPHOHYDROLASES; L CELLS (CELL LINE); MICE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RAL GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAS PROTEINS; REOVIRIDAE; REOVIRIDAE INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFECTION; VIRUS REPLICATION;

ANIMALIA; REOVIRUS SP.; RNA VIRUSES;

EID: 3342958748     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404310101     Document Type: Article

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