-
1
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed, N. N., H. L. Grimes, A. Bellacosa, T. O. Chan, and P. N. Tsichlis. 1997. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA 94:3627-3632.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
2
-
-
0027518574
-
Characterization of a guanine nucleotide dissociation stimulation for a rasrelated GTPase
-
Albright, C. F., B. W. Giddings, J. Liu, M. Vito, and R. A. Weinberg. 1993. Characterization of a guanine nucleotide dissociation stimulation for a rasrelated GTPase. EMBO J. 12:339-347.
-
(1993)
EMBO J.
, vol.12
, pp. 339-347
-
-
Albright, C.F.1
Giddings, B.W.2
Liu, J.3
Vito, M.4
Weinberg, R.A.5
-
3
-
-
0031022256
-
Anchorage-dependent cell cycle progression
-
Assoian, R. K. 1997. Anchorage-dependent cell cycle progression. J. Cell Biol. 13:1-4.
-
(1997)
J. Cell Biol.
, vol.13
, pp. 1-4
-
-
Assoian, R.K.1
-
4
-
-
0029001797
-
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GT-Pases
-
Cantor, S. B., T. Urano, and L. A. Feig. 1995. Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GT-Pases. Mol. Cell. Biol. 15:4578-4584.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4578-4584
-
-
Cantor, S.B.1
Urano, T.2
Feig, L.A.3
-
5
-
-
0028136688
-
A human oncogene of the RAS superfamily unmasked by expression cDNA cloning
-
Chan, A. M.-L., T. Miki, K. A. Meyers, and S. A. Aaronson. 1991. A human oncogene of the RAS superfamily unmasked by expression cDNA cloning. Proc. Natl. Acad. Sci. USA 91:7558-7562.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7558-7562
-
-
Chan, A.M.-L.1
Miki, T.2
Meyers, K.A.3
Aaronson, S.A.4
-
6
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK
-
Coso, O. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK. Cell 81:1137-1146.
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.-C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
7
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley, S., H. Paterson, K. Pauline, and C. J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-852.
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Pauline, K.3
Marshall, C.J.4
-
8
-
-
0028113884
-
R-ras induces malignant, but not morphologic, transformation of NIH3T3 cells
-
Cox, A. D., T. R. Brtva, D. G. Lowe, and C. J. Der. 1994. R-ras induces malignant, but not morphologic, transformation of NIH3T3 cells. Oncogene 9:3281-3288.
-
(1994)
Oncogene
, vol.9
, pp. 3281-3288
-
-
Cox, A.D.1
Brtva, T.R.2
Lowe, D.G.3
Der, C.J.4
-
9
-
-
0029807471
-
Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells
-
Datta, K., A. Bellacosa, T. O. Chan, and P. N. Tsichlis. 1996. Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells. J. Biol. Chem. 271:30835-30839.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30835-30839
-
-
Datta, K.1
Bellacosa, A.2
Chan, T.O.3
Tsichlis, P.N.4
-
10
-
-
0025230372
-
Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line
-
Drivas, G. T., A. Shih, E. Coutavas, M. G. Rush, and P. D'Eustachio. 1990. Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line. Mol. Cell. Biol. 10:1793-1798.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 1793-1798
-
-
Drivas, G.T.1
Shih, A.2
Coutavas, E.3
Rush, M.G.4
D'Eustachio, P.5
-
11
-
-
0031806711
-
Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes
-
D'Souza-Schorey, C., B. Boettner, and L. Van Aelst. 1998. Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Mol. Cell. Biol. 18:3936-3946.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3936-3946
-
-
D'Souza-Schorey, C.1
Boettner, B.2
Van Aelst, L.3
-
12
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek, H., S. R. Datta, T. F. Franke, M. J. Birnbaum, R. Yao, G. M. Cooper, R. A. Segal, D. R. Kaplan, and M. E. Greenberg. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275: 661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
13
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke, T. F., S. I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
16
-
-
0028260390
-
Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation
-
Graham, S. M., A. D. Cox, G. Drivas, M. G. Rush, P. D'Eustachio, and C. J. Der. 1994. Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation. Mol. Cell. Biol. 14:4108-4115.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4108-4115
-
-
Graham, S.M.1
Cox, A.D.2
Drivas, G.3
Rush, M.G.4
D'Eustachio, P.5
Der, C.J.6
-
17
-
-
0031024083
-
R-Ras is regulated by activators and effectors distinct from those that control Ras function
-
Huff, S. Y., L. A. Quilliam, A. D. Cox, and C. J. Der. 1997. R-Ras is regulated by activators and effectors distinct from those that control Ras function. Oncogene 14:133-143.
-
(1997)
Oncogene
, vol.14
, pp. 133-143
-
-
Huff, S.Y.1
Quilliam, L.A.2
Cox, A.D.3
Der, C.J.4
-
18
-
-
0030909050
-
Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway
-
Hughes, P. E., M. W. Renshaw, M. Pfaff, J. Forsyth, V. M. Keivens, M. A. Schwartz, and M. H. Ginsberg. 1997. Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway. Cell 88:521-530.
-
(1997)
Cell
, vol.88
, pp. 521-530
-
-
Hughes, P.E.1
Renshaw, M.W.2
Pfaff, M.3
Forsyth, J.4
Keivens, V.M.5
Schwartz, M.A.6
Ginsberg, M.H.7
-
19
-
-
0030052368
-
Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS
-
Joneson, T., M. A. White, M. H. Wigler, and D. Bar-Sagi. 1996. Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science 271:810-812.
-
(1996)
Science
, vol.271
, pp. 810-812
-
-
Joneson, T.1
White, M.A.2
Wigler, M.H.3
Bar-Sagi, D.4
-
20
-
-
0029802561
-
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
-
Joneson, T., M. McDonough, D. Bar-Sagi, and L. Van Aelst. 1996. RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science 274:1374-1376.
-
(1996)
Science
, vol.274
, pp. 1374-1376
-
-
Joneson, T.1
McDonough, M.2
Bar-Sagi, D.3
Van Aelst, L.4
-
21
-
-
0029089074
-
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity
-
Jullien-Flores, V., O. Dorseuil, F. Romero, F. Letourneur, S. Saragosti, R. Berger, A. Tavitian, G. Gacon, and J. H. Camonis. 1995. Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. J. Biol. Chem. 270:22473-22477.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22473-22477
-
-
Jullien-Flores, V.1
Dorseuil, O.2
Romero, F.3
Letourneur, F.4
Saragosti, S.5
Berger, R.6
Tavitian, A.7
Gacon, G.8
Camonis, J.H.9
-
22
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh, A., P. Rodriguez-Viciana, E. Ulrich, C. Gilbert, P. Coffer, J. Downward, and G. Evan. 1997. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385:544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
23
-
-
0029890896
-
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
Khosravi-Far, R., M. A. White, J. K. Westwick, P. A. Solski, M. Chrzanowska-Wodnicka, L. Van Aelst, M. H. Wigler, and C. J. Der. 1996. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol. Cell. Biol. 16:3923-3933.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowska-Wodnicka, M.5
Van Aelst, L.6
Wigler, M.H.7
Der, C.J.8
-
24
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., P. Rodriguez-Viciana, S. Wennstrom, P. H. Warne, and J. Downward. 1997. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16:2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
25
-
-
0030723061
-
Identification and characterization of R-ras3: A novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution
-
Kimmelman, A., T. Tolkacheva, M. V. Lorenzi, M. Osada, and A. M.-L. Chan. 1997. Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution. Oncogene 15:2675-2686.
-
(1997)
Oncogene
, vol.15
, pp. 2675-2686
-
-
Kimmelman, A.1
Tolkacheva, T.2
Lorenzi, M.V.3
Osada, M.4
Chan, A.M.-L.5
-
26
-
-
0030839766
-
Phosphatidylinositol 3-kinase is required for integrin-stimulated Akt and Raf-1/mitogen-activated protein kinase pathway activation
-
King, W. G., M. D. Mattaliano, T. O. Chan, P. N. Tsichlis, and J. S. Brugge. 1997. Phosphatidylinositol 3-kinase is required for integrin-stimulated Akt and Raf-1/mitogen-activated protein kinase pathway activation. Mol. Cell. Biol. 17:4406-4418.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4406-4418
-
-
King, W.G.1
Mattaliano, M.D.2
Chan, T.O.3
Tsichlis, P.N.4
Brugge, J.S.5
-
27
-
-
0031708412
-
Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation
-
Klippel, A., M. A. Escobedo, M. S. Wachowicz, I. G. Apel, T. W. Brown, M. A. Giedlin, W. M. Kavanaugh, and L. T. Williams. 1998. Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation. Mol. Cell. Biol. 18:5699-5711.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5699-5711
-
-
Klippel, A.1
Escobedo, M.A.2
Wachowicz, M.S.3
Apel, I.G.4
Brown, T.W.5
Giedlin, M.A.6
Kavanaugh, W.M.7
Williams, L.T.8
-
28
-
-
0030298138
-
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
-
Lamarche, N., N. Tapon, L. Stowers, P. D. Burbelo, P. Aspenstrom, T. Bridges, J. Chant, and A. Hall. 1996. Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell 87:519-529.
-
(1996)
Cell
, vol.87
, pp. 519-529
-
-
Lamarche, N.1
Tapon, N.2
Stowers, L.3
Burbelo, P.D.4
Aspenstrom, P.5
Bridges, T.6
Chant, J.7
Hall, A.8
-
29
-
-
0023657439
-
Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes
-
Lowe, D. G., D. J. Capon, E. Delwart, A. Y. Sakaguchi, S. L. Naylor, and D. V. Goeddel. 1987. Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes. Cell 48:137-146.
-
(1987)
Cell
, vol.48
, pp. 137-146
-
-
Lowe, D.G.1
Capon, D.J.2
Delwart, E.3
Sakaguchi, A.Y.4
Naylor, S.L.5
Goeddel, D.V.6
-
30
-
-
0031038131
-
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways
-
Marte, B. M., P. Rodriguez-Viciana, S. Wennstrom, P. H. Warne, and J. Downward. 1997. R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways. Curr. Biol. 7:63-70.
-
(1997)
Curr. Biol.
, vol.7
, pp. 63-70
-
-
Marte, B.M.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
31
-
-
0027292678
-
Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta
-
Mischak, H., J. H. Pierce, J. Goodnight, M. G. Kazanietz, P. M. Blumberg, and J. F. Mushinski. 1993. Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta. J. Biol. Chem. 268:20110-20115.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20110-20115
-
-
Mischak, H.1
Pierce, J.H.2
Goodnight, J.3
Kazanietz, M.G.4
Blumberg, P.M.5
Mushinski, J.F.6
-
32
-
-
0032563295
-
Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinase gamma
-
Murga, C., L. Laguinge, R. Wetzker, A. Cuadrado, and J. S. Gutkind. 1998. Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinase gamma. J. Biol. Chem. 273: 19080-19085.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19080-19085
-
-
Murga, C.1
Laguinge, L.2
Wetzker, R.3
Cuadrado, A.4
Gutkind, J.S.5
-
33
-
-
0029588356
-
A putative effector of Ral has homology to Rho/Rac GTPase activating proteins
-
Park, S. H., and R. A. Weinberg. 1995. A putative effector of Ral has homology to Rho/Rac GTPase activating proteins. Oncogene 11:2349-2355.
-
(1995)
Oncogene
, vol.11
, pp. 2349-2355
-
-
Park, S.H.1
Weinberg, R.A.2
-
34
-
-
0023847924
-
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells
-
Pierce, J. H., M. Ruggiero, T. P. Fleming, P. P. Di Fiore, J. S. Greenberger, L. Varticovski, J. Schlessinger, G. Rovera, and S. A. Aaronson. 1988. Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science 239:628-631.
-
(1988)
Science
, vol.239
, pp. 628-631
-
-
Pierce, J.H.1
Ruggiero, M.2
Fleming, T.P.3
Di Fiore, P.P.4
Greenberger, J.S.5
Varticovski, L.6
Schlessinger, J.7
Rovera, G.8
Aaronson, S.A.9
-
35
-
-
0024534377
-
Changes in integrin receptors on oncogenically transformed cells
-
Plantefaber, L. C., and R. O. Hynes. 1989. Changes in integrin receptors on oncogenically transformed cells. Cell 56:281-290.
-
(1989)
Cell
, vol.56
, pp. 281-290
-
-
Plantefaber, L.C.1
Hynes, R.O.2
-
36
-
-
0029057465
-
Critical role of Rho in cell transformation by oncogenic Ras
-
Prendergast, G. C., R. Khosravi-Far, P. A. Solski, H. Kurzawa, P. F. Lebowitz, and C. J. Der. 1995. Critical role of Rho in cell transformation by oncogenic Ras. Oncogene 10:2289-2296.
-
(1995)
Oncogene
, vol.10
, pp. 2289-2296
-
-
Prendergast, G.C.1
Khosravi-Far, R.2
Solski, P.A.3
Kurzawa, H.4
Lebowitz, P.F.5
Der, C.J.6
-
37
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qiu, R.-G., J. Chen, D. Kirn, F. McCormick, and M. Symons. 1995. An essential role for Rac in Ras transformation. Nature 374:457-459.
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.-G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
38
-
-
0030992814
-
Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
-
Qiu, R. G., A. Abo, F. McCormick, and M. Symons. 1997. Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol. Cell. Biol. 17:3449-3458.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3449-3458
-
-
Qiu, R.G.1
Abo, A.2
McCormick, F.3
Symons, M.4
-
39
-
-
0029559310
-
A role for Rho in Ras transformation
-
Qiu, R. G., J. Chen, F. McCormick, and M. Symons. 1995. A role for Rho in Ras transformation. Proc. Natl. Acad. Sci. USA 92:11781-11785.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11781-11785
-
-
Qiu, R.G.1
Chen, J.2
McCormick, F.3
Symons, M.4
-
40
-
-
0032545497
-
The death effector domain of PEA-15 is involved in its regulation of integrin activation
-
Ramos, J. W., T. K. Kojima, P. E. Hughes, C. A. Fenczik, and M. H. Ginsberg. 1998. The death effector domain of PEA-15 is involved in its regulation of integrin activation. J. Biol. Chem. 273:33897-33900.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33897-33900
-
-
Ramos, J.W.1
Kojima, T.K.2
Hughes, P.E.3
Fenczik, C.A.4
Ginsberg, M.H.5
-
41
-
-
0028144704
-
R-ras interacts with ras-GAP, neurofibromin and c-raf but does not regulate cell growth or differentiation
-
Rey, I., P. Taylor-Harris, H. Van Erp, and A. Hall. 1994. R-ras interacts with ras-GAP, neurofibromin and c-raf but does not regulate cell growth or differentiation. Oncogene 9:685-692.
-
(1994)
Oncogene
, vol.9
, pp. 685-692
-
-
Rey, I.1
Taylor-Harris, P.2
Van Erp, H.3
Hall, A.4
-
42
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., P. H. Warne, A. Khwaja, B. M. Marte, D. Pappin, P. Das, M. D. Waterfield, A. Ridley, and J. Downward. 1997. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 89:457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
43
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., P. H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M. J. Fry, M. D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370:527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
44
-
-
0029990003
-
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
-
Rodriguez-Viciana, P., P. H. Warne, B. Vanhaesebroeck, M. D. Waterfield, and J. Downward. 1996. Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J. 15:2442-2451.
-
(1996)
EMBO J.
, vol.15
, pp. 2442-2451
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Vanhaesebroeck, B.3
Waterfield, M.D.4
Downward, J.5
-
45
-
-
0028136185
-
Oncogenic activation of human R-ras by point mutations analogous to those of prototype H-ras oncogenes
-
Saez, R., A. M.-L. Chan, T. Miki, and S. A. Aaronson. 1994. Oncogenic activation of human R-ras by point mutations analogous to those of prototype H-ras oncogenes. Oncogene 9:2977-2982.
-
(1994)
Oncogene
, vol.9
, pp. 2977-2982
-
-
Saez, R.1
Chan, A.M.-L.2
Miki, T.3
Aaronson, S.A.4
-
46
-
-
0030867904
-
Interleukin 3-dependent survival by the Akt protein kinase
-
Songyang, Z., D. Baltimore, L. C. Cantley, D. R. Kaplan, and T. F. Franke. 1997. Interleukin 3-dependent survival by the Akt protein kinase. Proc. Natl. Acad. Sci. USA 94:11345-11350.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11345-11350
-
-
Songyang, Z.1
Baltimore, D.2
Cantley, L.C.3
Kaplan, D.R.4
Franke, T.F.5
-
47
-
-
0028577298
-
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap
-
Spaargaren, M., and J. R. Bischoff. 1994. Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. Proc. Natl. Acad. Sci. USA 91:12609-12613.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12609-12613
-
-
Spaargaren, M.1
Bischoff, J.R.2
-
48
-
-
0028175939
-
The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner
-
Spaargaren, M., G. A. Martin, F. McCormick, M. J. Fernandez-Sarabia, and J. R. Bischof. 1994. The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner. Biochem. J. 300:303-307.
-
(1994)
Biochem. J.
, vol.300
, pp. 303-307
-
-
Spaargaren, M.1
Martin, G.A.2
McCormick, F.3
Fernandez-Sarabia, M.J.4
Bischof, J.R.5
-
49
-
-
0033548484
-
A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf
-
Sutor, S. L., B. T. Vroman, E. A. Armstrong, R. T. Abraham, and L. M. Karnitz. 1999. A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf. J. Biol. Chem. 274:7002-7010.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7002-7010
-
-
Sutor, S.L.1
Vroman, B.T.2
Armstrong, E.A.3
Abraham, R.T.4
Karnitz, L.M.5
-
50
-
-
0030715570
-
An activated mutant of R-Ras inhibits cell death caused by cytokine deprivation in BaF3 cells in the presence of IGF-I
-
Suzuki, J., Y. Kaziro, and H. Koide. 1997. An activated mutant of R-Ras inhibits cell death caused by cytokine deprivation in BaF3 cells in the presence of IGF-I. Oncogene 15:1689-1697.
-
(1997)
Oncogene
, vol.15
, pp. 1689-1697
-
-
Suzuki, J.1
Kaziro, Y.2
Koide, H.3
-
51
-
-
0029029743
-
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism
-
Wang, H. G., J. A. Millan, A. D. Cox, C. J. Der, U. R. Rapp, T. Beck, H. Zha, and J. C. Reed. 1995. R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. J. Cell Biol. 129:1103-1114.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1103-1114
-
-
Wang, H.G.1
Millan, J.A.2
Cox, A.D.3
Der, C.J.4
Rapp, U.R.5
Beck, T.6
Zha, H.7
Reed, J.C.8
-
52
-
-
0031026132
-
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
-
Westwick, J. K., Q. T. Lambert, G. J. Clark, M. Symons, L. Van Aelst, R. G. Pestell, and C. J. Der. 1997. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol. Cell. Biol. 17:1324-1335.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1324-1335
-
-
Westwick, J.K.1
Lambert, Q.T.2
Clark, G.J.3
Symons, M.4
Van Aelst, L.5
Pestell, R.G.6
Der, C.J.7
-
53
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White, M. A., C. Nicolette, A. Minden, A. Polverino, L. Van Aelst, M. Karin, and M. H. Wigler. 1995. Multiple Ras functions can contribute to mammalian cell transformation. Cell 80:533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicolette, C.2
Minden, A.3
Polverino, A.4
Van Aelst, L.5
Karin, M.6
Wigler, M.H.7
-
54
-
-
0029950722
-
A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
-
White, M. A., T. Vale, J. H. Camonis, E. Schaefer, and M. H. Wigler. 1996. A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J. Biol. Chem. 271:16439-16442.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16439-16442
-
-
White, M.A.1
Vale, T.2
Camonis, J.H.3
Schaefer, E.4
Wigler, M.H.5
-
55
-
-
0017647917
-
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells
-
Wigler, M., S. Silverstein, L. S. Lee, A. Pellicer, Y. C. Cheng, and R. Axel. 1977. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell 11:223-232.
-
(1977)
Cell
, vol.11
, pp. 223-232
-
-
Wigler, M.1
Silverstein, S.2
Lee, L.S.3
Pellicer, A.4
Cheng, Y.C.5
Axel, R.6
-
56
-
-
0031944085
-
Activation of the small GTPase Ral in platelets
-
Wolthuis, R. M., B. Franke, M. van Triest, B. Bauer, R. H. Cool, J. H. Camonis, J. W. Akkerman, and J. L. Bos. 1998. Activation of the small GTPase Ral in platelets. Mol. Cell. Biol. 18:2486-2491.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2486-2491
-
-
Wolthuis, R.M.1
Franke, B.2
Van Triest, M.3
Bauer, B.4
Cool, R.H.5
Camonis, J.H.6
Akkerman, J.W.7
Bos, J.L.8
-
57
-
-
0031943640
-
Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth
-
Yang, J. J., J. S. Kang, and R. S. Krauss. 1998. Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth. Mol. Cell. Biol. 18:2586-2595.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2586-2595
-
-
Yang, J.J.1
Kang, J.S.2
Krauss, R.S.3
-
58
-
-
0029870339
-
Integrin activation by R-ras
-
Zhang, Z., K. Vuori, H. G. Wang, J. C. Reed, and E. Ruoslahti. 1996. Integrin activation by R-ras. Cell 85:61-69.
-
(1996)
Cell
, vol.85
, pp. 61-69
-
-
Zhang, Z.1
Vuori, K.2
Wang, H.G.3
Reed, J.C.4
Ruoslahti, E.5
|