메뉴 건너뛰기




Volumn 12, Issue 8, 2004, Pages 394-398

The role of Paneth cells and their antimicrobial peptides in innate host defense

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; ANTIINFECTIVE AGENT; CRYPTDIN 1; CRYPTDIN 2; CRYPTDIN 3; CRYPTDIN 4; CRYPTDIN 5; CRYPTDIN 6; DEFENSIN; FAS ANTIGEN; MATRILYSIN; PEPTIDE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 3342908873     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2004.06.007     Document Type: Review
Times cited : (105)

References (54)
  • 1
    • 0019386682 scopus 로고
    • Sequence and specificity of two antibacterial proteins involved in insect immunity
    • Steiner H., et al. Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature. 292:1981;246-268
    • (1981) Nature , vol.292 , pp. 246-268
    • Steiner, H.1
  • 2
    • 0029347190 scopus 로고
    • Plant defensins: Novel antimicrobial peptides as components of the host defense system
    • Broekaert W.F., et al. Plant defensins: novel antimicrobial peptides as components of the host defense system. Plant Physiol. 108:1995;1353-1358
    • (1995) Plant Physiol. , vol.108 , pp. 1353-1358
    • Broekaert, W.F.1
  • 3
    • 0344196897 scopus 로고    scopus 로고
    • Innate immunity: Involvement of new neuropeptides
    • Metz-Boutigue M.H., et al. Innate immunity: involvement of new neuropeptides. Trends Microbiol. 11:2003;585-592
    • (2003) Trends Microbiol. , vol.11 , pp. 585-592
    • Metz-Boutigue, M.H.1
  • 4
    • 0030957967 scopus 로고    scopus 로고
    • Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder
    • Cole A.M., et al. Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder. J. Biol. Chem. 272:1997;12008-12013
    • (1997) J. Biol. Chem. , vol.272 , pp. 12008-12013
    • Cole, A.M.1
  • 5
    • 2042513493 scopus 로고
    • Magainins, a class of antimicrobial peptides from Xenopus skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor
    • Zasloff M. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc. Natl. Acad. Sci. U. S. A. 84:1987;5449-5453
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 5449-5453
    • Zasloff, M.1
  • 6
    • 0022395334 scopus 로고
    • Primary structure of three human neutrophil defensins
    • Selsted M.E., et al. Primary structure of three human neutrophil defensins. J. Clin. Invest. 76:1985;1436-1439
    • (1985) J. Clin. Invest. , vol.76 , pp. 1436-1439
    • Selsted, M.E.1
  • 7
    • 0032005344 scopus 로고    scopus 로고
    • Antimicrobial peptides of vertebrates
    • Ganz T., Lehrer R.I. Antimicrobial peptides of vertebrates. Curr. Opin. Immunol. 10:1998;41-44
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 41-44
    • Ganz, T.1    Lehrer, R.I.2
  • 8
    • 0028902757 scopus 로고
    • Epithelial antibiotics induced at sites of inflammation
    • Schonwetter B.S., et al. Epithelial antibiotics induced at sites of inflammation. Science. 267:1995;1645-1648
    • (1995) Science , vol.267 , pp. 1645-1648
    • Schonwetter, B.S.1
  • 9
    • 0028051542 scopus 로고
    • Mouse Paneth cell defensins: Primary structures and antibacterial activities of numerous cryptdin isoforms
    • Ouellette A.J., et al. Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms. Infect. Immun. 62:1994;5040-5047
    • (1994) Infect. Immun. , vol.62 , pp. 5040-5047
    • Ouellette, A.J.1
  • 10
    • 0026457997 scopus 로고
    • Paneth cells of the human small intestine express an antimicrobial peptide gene
    • Jones D.E., Bevins C.L. Paneth cells of the human small intestine express an antimicrobial peptide gene. J. Biol. Chem. 267:1992;23216-23225
    • (1992) J. Biol. Chem. , vol.267 , pp. 23216-23225
    • Jones, D.E.1    Bevins, C.L.2
  • 11
    • 0037340434 scopus 로고    scopus 로고
    • Angiogenins: A new class of microbicidal proteins involved in innate immunity
    • Hooper L.V., et al. Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat. Immunol. 4:2003;269-273
    • (2003) Nat. Immunol. , vol.4 , pp. 269-273
    • Hooper, L.V.1
  • 12
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., et al. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1
  • 13
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S., et al. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:2001;675-680
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1
  • 14
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • Takeda K., et al. Toll-like receptors. Annu. Rev. Immunol. 21:2003;335-376
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 335-376
    • Takeda, K.1
  • 15
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B., et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell. 75:1993;253-261
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1
  • 16
    • 0029074399 scopus 로고
    • Interleukin-7 is produced by human intestinal cells and regulates the proliferation of intestinal mucosal lymphocytes
    • Watanabe M., et al. Interleukin-7 is produced by human intestinal cells and regulates the proliferation of intestinal mucosal lymphocytes. J. Clin. Invest. 95:1995;2945-2953
    • (1995) J. Clin. Invest. , vol.95 , pp. 2945-2953
    • Watanabe, M.1
  • 17
    • 0034800289 scopus 로고    scopus 로고
    • Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease
    • Kanai T., et al. Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease. Gastroenterology. 121:2001;875-888
    • (2001) Gastroenterology , vol.121 , pp. 875-888
    • Kanai, T.1
  • 18
    • 2042495252 scopus 로고
    • Ueber die secernierenden Zellen des Duenndarmepithels
    • Paneth J. Ueber die secernierenden Zellen des Duenndarmepithels. Archiv. Mikr. Anat. 31:1888;113-191
    • (1888) Archiv. Mikr. Anat. , vol.31 , pp. 113-191
    • Paneth, J.1
  • 19
    • 0030731743 scopus 로고    scopus 로고
    • Paneth cells and innate immunity in the crypt microenvironment
    • Ouellette A.J. Paneth cells and innate immunity in the crypt microenvironment. Gastroenterology. 113:1997;1779-1784
    • (1997) Gastroenterology , vol.113 , pp. 1779-1784
    • Ouellette, A.J.1
  • 20
    • 0030913746 scopus 로고    scopus 로고
    • Broad-spectrum antimicrobial activity of human intestinal defensin 5
    • Porter E.M., et al. Broad-spectrum antimicrobial activity of human intestinal defensin 5. Infect. Immun. 65:1997;2396-2401
    • (1997) Infect. Immun. , vol.65 , pp. 2396-2401
    • Porter, E.M.1
  • 21
    • 0026663420 scopus 로고
    • Lysozyme gene expression in inflammatory bowel disease
    • Stamp G.W., et al. Lysozyme gene expression in inflammatory bowel disease. Gastroenterology. 103:1992;532-538
    • (1992) Gastroenterology , vol.103 , pp. 532-538
    • Stamp, G.W.1
  • 22
    • 0025133975 scopus 로고
    • Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization
    • Keshav S., et al. Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization. J. Exp. Med. 171:1990;327-332
    • (1990) J. Exp. Med. , vol.171 , pp. 327-332
    • Keshav, S.1
  • 23
    • 0035948617 scopus 로고    scopus 로고
    • Identification of xanthine dehydrogenase/xanthine oxidase as a rat Paneth cell zinc-binding protein
    • Morita Y., et al. Identification of xanthine dehydrogenase/xanthine oxidase as a rat Paneth cell zinc-binding protein. Biochim. Biophys. Acta. 1540:2001;43-49
    • (2001) Biochim. Biophys. Acta , vol.1540 , pp. 43-49
    • Morita, Y.1
  • 24
    • 0036161792 scopus 로고    scopus 로고
    • The multifaceted Paneth cell
    • Porter E.M., et al. The multifaceted Paneth cell. Cell. Mol. Life Sci. 59:2002;156-170
    • (2002) Cell. Mol. Life Sci. , vol.59 , pp. 156-170
    • Porter, E.M.1
  • 25
    • 0038109983 scopus 로고    scopus 로고
    • Crohn's disease and the NOD2 gene: A role for paneth cells
    • Lala S., et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology. 125:2003;47-57
    • (2003) Gastroenterology , vol.125 , pp. 47-57
    • Lala, S.1
  • 26
    • 0035024206 scopus 로고    scopus 로고
    • Paneth cell defensins and innate immunity of the small bowel
    • Ouellette A.J., Bevins C.L. Paneth cell defensins and innate immunity of the small bowel. Inflamm. Bowel Dis. 7:2001;43-50
    • (2001) Inflamm. Bowel Dis. , vol.7 , pp. 43-50
    • Ouellette, A.J.1    Bevins, C.L.2
  • 27
    • 0022457211 scopus 로고
    • Quantitative light microscopic observations on Paneth cells of germ-free and ex-germ-free Wistar rats
    • Satoh Y., et al. Quantitative light microscopic observations on Paneth cells of germ-free and ex-germ-free Wistar rats. Digestion. 34:1986;115-121
    • (1986) Digestion , vol.34 , pp. 115-121
    • Satoh, Y.1
  • 28
    • 0022638082 scopus 로고
    • Quantitative electron microscopic observations on Paneth cells of germfree and ex-germfree Wistar rats
    • Satoh Y., Vollrath L. Quantitative electron microscopic observations on Paneth cells of germfree and ex-germfree Wistar rats. Anat. Embryol. 173:1986;317-322
    • (1986) Anat. Embryol. , vol.173 , pp. 317-322
    • Satoh, Y.1    Vollrath, L.2
  • 29
    • 0028907433 scopus 로고
    • Carbamylcholine- and catecholamine-induced intracellular calcium dynamics of epithelial cells in mouse ileal crypts
    • Satoh Y., et al. Carbamylcholine- and catecholamine-induced intracellular calcium dynamics of epithelial cells in mouse ileal crypts. Gastroenterology. 108:1995;1345-1356
    • (1995) Gastroenterology , vol.108 , pp. 1345-1356
    • Satoh, Y.1
  • 30
    • 0030863618 scopus 로고    scopus 로고
    • Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice
    • Garabedian E.M., et al. Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice. J. Biol. Chem. 272:1997;23729-23740
    • (1997) J. Biol. Chem. , vol.272 , pp. 23729-23740
    • Garabedian, E.M.1
  • 31
    • 0033214433 scopus 로고    scopus 로고
    • Regulation of intestinal α-defensin activation by the metalloproteinase matrilysin in innate host defense
    • Wilson C.L., et al. Regulation of intestinal α-defensin activation by the metalloproteinase matrilysin in innate host defense. Science. 286:1999;113-117
    • (1999) Science , vol.286 , pp. 113-117
    • Wilson, C.L.1
  • 32
    • 0037085279 scopus 로고    scopus 로고
    • Activation of Paneth cell α-defensins in mouse small intestine
    • Ayabe T., et al. Activation of Paneth cell α-defensins in mouse small intestine. J. Biol. Chem. 277:2002;5219-5228
    • (2002) J. Biol. Chem. , vol.277 , pp. 5219-5228
    • Ayabe, T.1
  • 33
    • 0036079594 scopus 로고    scopus 로고
    • Paneth cell trypsin is the processing enzyme for human defensin-5
    • Ghosh D., et al. Paneth cell trypsin is the processing enzyme for human defensin-5. Nat. Immunol. 3:2002;583-590
    • (2002) Nat. Immunol. , vol.3 , pp. 583-590
    • Ghosh, D.1
  • 34
    • 0035128862 scopus 로고    scopus 로고
    • Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disese
    • Cunliffe R.N., et al. Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disese. Gut. 48:2001;176-185
    • (2001) Gut , vol.48 , pp. 176-185
    • Cunliffe, R.N.1
  • 35
    • 0034252293 scopus 로고    scopus 로고
    • Secretion of microbicidal -defensins by intestinal Paneth cells in response to bacteria
    • Ayabe T., et al. Secretion of microbicidal -defensins by intestinal Paneth cells in response to bacteria. Nat. Immunol. 1:2000;113-118
    • (2000) Nat. Immunol. , vol.1 , pp. 113-118
    • Ayabe, T.1
  • 36
    • 0036479232 scopus 로고    scopus 로고
    • 2+-activated, intermediate conductance Potassium channel
    • 2+-activated, intermediate conductance Potassium channel. J. Biol. Chem. 277:2002;3793-3800
    • (2002) J. Biol. Chem. , vol.277 , pp. 3793-3800
    • Ayabe, T.1
  • 37
    • 0037417311 scopus 로고    scopus 로고
    • Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
    • Salzman N.H., et al. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature. 422:2003;522-526
    • (2003) Nature , vol.422 , pp. 522-526
    • Salzman, N.H.1
  • 38
    • 0037372643 scopus 로고    scopus 로고
    • Enteric Salmonella infection inhibits Paneth cell antimicrobial peptide expression
    • Salzman N.H., et al. Enteric Salmonella infection inhibits Paneth cell antimicrobial peptide expression. Infect. Immun. 71:2003;1109-1115
    • (2003) Infect. Immun. , vol.71 , pp. 1109-1115
    • Salzman, N.H.1
  • 39
    • 0029870085 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
    • Smith J.J., et al. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell. 85:1996;229-236
    • (1996) Cell , vol.85 , pp. 229-236
    • Smith, J.J.1
  • 40
    • 0030949875 scopus 로고    scopus 로고
    • Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman M.J., et al. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell. 88:1997;553-560
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.J.1
  • 41
    • 0035936156 scopus 로고    scopus 로고
    • Innate antimicrobial peptide protects the skin from invasive bacterial infection
    • Nizet V., et al. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 414:2001;454-457
    • (2001) Nature , vol.414 , pp. 454-457
    • Nizet, V.1
  • 42
    • 0037057645 scopus 로고    scopus 로고
    • Endogenous antimicrobial peptides and skin infections in atopic dermatitis
    • Ong P.Y., et al. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N. Engl. J. Med. 347:2002;1151-1160
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1151-1160
    • Ong, P.Y.1
  • 43
    • 0031844367 scopus 로고    scopus 로고
    • Enteric defensin expression in necrotizing enterocolitis
    • Salzman N.H., et al. Enteric defensin expression in necrotizing enterocolitis. Pediatr. Res. 44:1998;20-26
    • (1998) Pediatr. Res. , vol.44 , pp. 20-26
    • Salzman, N.H.1
  • 44
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot J.P., et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 31:2001;599-603
    • (2001) Nature , vol.31 , pp. 599-603
    • Hugot, J.P.1
  • 45
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y., et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 31:2001;603-606
    • (2001) Nature , vol.31 , pp. 603-606
    • Ogura, Y.1
  • 46
    • 0035078647 scopus 로고    scopus 로고
    • Antimycobacterial agent based on mRNA encoding human β-Defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis
    • Kisich K.O. Antimycobacterial agent based on mRNA encoding human β-Defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis. Infect. Immun. 69:2001;2692-2699
    • (2001) Infect. Immun. , vol.69 , pp. 2692-2699
    • Kisich, K.O.1
  • 47
    • 0032708355 scopus 로고    scopus 로고
    • Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide
    • Bals R. Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide. Infect. Immun. 67:1999;6084-6089
    • (1999) Infect. Immun. , vol.67 , pp. 6084-6089
    • Bals, R.1
  • 48
    • 0027488740 scopus 로고
    • Structure and orientation of the antibiotic peptide magainin in membranes by solid-state nuclear magnetic resonance spectroscopy
    • Bechinger B., et al. Structure and orientation of the antibiotic peptide magainin in membranes by solid-state nuclear magnetic resonance spectroscopy. Protein Sci. 2:1993;2077-2084
    • (1993) Protein Sci. , vol.2 , pp. 2077-2084
    • Bechinger, B.1
  • 49
    • 0028920870 scopus 로고
    • Structure-activity studies on magainins and other host defense peptides
    • Maloy W.L., Kari U.P. Structure-activity studies on magainins and other host defense peptides. Biopolymers. 37:1995;105-122
    • (1995) Biopolymers , vol.37 , pp. 105-122
    • Maloy, W.L.1    Kari, U.P.2
  • 50
    • 0032693639 scopus 로고    scopus 로고
    • Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes
    • Matsuzaki K. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim. Biophys. Acta. 1462:1999;1-10
    • (1999) Biochim. Biophys. Acta , vol.1462 , pp. 1-10
    • Matsuzaki, K.1
  • 51
    • 0029819784 scopus 로고    scopus 로고
    • Paneth cell defensins: Endogenous peptide components of intestinal host defense
    • Ouellette A.J., Selsted M.E. Paneth cell defensins: endogenous peptide components of intestinal host defense. FASEB J. 10:1996;1280-1289
    • (1996) FASEB J. , vol.10 , pp. 1280-1289
    • Ouellette, A.J.1    Selsted, M.E.2
  • 52
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M. Antimicrobial peptides of multicellular organisms. Nature. 415:2002;389-395
    • (2002) Nature , vol.415 , pp. 389-395
    • Zasloff, M.1
  • 53
    • 0026722445 scopus 로고
    • Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils
    • Selsted M.E., et al. Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils. J. Biol. Chem. 267:1992;4292-4295
    • (1992) J. Biol. Chem. , vol.267 , pp. 4292-4295
    • Selsted, M.E.1
  • 54
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins
    • Tang Y.Q., et al. A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science. 286:1999;498-502
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.