Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1

Journal of Cell Biology

Volumn 160, Issue 1, 2003, Pages 17-23

  Innocenti, Metello ^a   Frittoli, Emanuela ^a   Ponzanelli, Isabella ^a   Falck, John R ^e   Brachmann, Saskia M ^b   Di Fiore, Pier Paolo ^a,c,d   Scita, Giorgio ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e NONE

Author keywords

Actin remodeling; GEF; PI3K; RTK; Signaling

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN ABI1; PROTEIN EPS8; PROTEIN P85; PROTEIN TYROSINE KINASE; RAC PROTEIN; SOS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ARABIDOPSIS PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COS CELLS; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; FIBROBLASTS; GENETIC VECTORS; GLUTATHIONE TRANSFERASE; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEIN PHOSPHATASE; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SOS1 PROTEIN; TRANSFECTION;

ANIMALIA;

EID: 0037421209     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200206079     Document Type: Article

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