Syntheses and radiofluorination of two derivatives of 5-cyano-indole as selective ligands for the dopamine subtype-4 receptor

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 1, 2006, Pages 55-70

  Tietze, Rainer ^a   Hocke, Carsten ^a   Löber, Stefan ^a   Hübner, Harald ^a   Kuwert, Torsten ^a   Gmeiner, Peter ^a   Prante, Olaf ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

18F fluoroethylation; D4 receptor; F 18; Indole; Pet; Positron emission tomography

Indexed keywords

AMINES; BINDING ENERGY; ELECTRONS; LIGANDS; NEUROPHYSIOLOGY; POLYCYCLIC AROMATIC HYDROCARBONS; POSITRONS; SULFUR COMPOUNDS;

18F-FLUOROETHYLATION; CARBONITRILES; D4 RECEPTOR; DOPAMINE; F-18; INDOLE; LABELINGS; PET; RADIOFLUORINATION; SELECTIVE LIGANDS;

POSITRON EMISSION TOMOGRAPHY;

2 [4 [2 (2 FLUOROETHOXY)PHENYL]PIPERAZIN 1 YLMETHYL]INDOLE 5 CARBONITRILE; 2 [4 [4 (2 FLUOROETHOXY)PHENYL]PIPERAZIN 1 YLMETHYL]INDOLE 5 CARBONITRILE; DOPAMINE 4 RECEPTOR; FLUORINE 18; INDOLE DERIVATIVE; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; DRUG RECEPTOR BINDING; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

ANIMALIA;

EID: 32644451471     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1026     Document Type: Article

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