Design and synthesis of 2-naphthoate esters as selective dopamine D4 antagonists

Journal of Medicinal Chemistry

Volumn 39, Issue 10, 1996, Pages 1946-1948

  Boyfield, Izzy ^a   Brown, Thomas H ^a   Coldwell, Martyn C ^a   Cooper, David G ^a   Hadley, Michael S ^a   Hagan, Jim J ^a   Healy, Maureen A ^a   Johns, Amanda ^a   King, Ron J ^a   Middlemiss, Derek N ^a   Nash, David J ^a   Riley, Graham J ^a   Scott, Emma E ^a   Smith, Stephen A ^a   Stemp, Geoffrey ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 NAPHTHOIC ACID DERIVATIVE; 2 PHENYL 4 [4 (2 PYRIMIDINYL) 1 PIPERAZINYLMETHYL]IMIDAZOLE; CLOZAPINE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; EMONAPRIDE; HALOPERIDOL; SULPIRIDE;

ARTICLE; DRUG DESIGN; DRUG EFFICACY; DRUG SELECTIVITY; DRUG SYNTHESIS; EXTRAPYRAMIDAL SYMPTOM; HUMAN; RECEPTOR DENSITY; SCHIZOPHRENIA;

DOPAMINE ANTAGONISTS; DRUG DESIGN; ESTERS; HUMANS; NAPHTHALENES; RADIOLIGAND ASSAY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4;

EID: 15844382453     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960017l     Document Type: Article

References (15)

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