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Volumn 29, Issue 2, 2002, Pages 233-241

Syntheses and pharmacological evaluation of two potent antagonists for dopamine D4 receptors: [11C]YM-50001 and N-[2-[4-(4-Chlorophenyl)-piperizin-1-yl]ethyl]-3-[11C] methoxybenzamide

(9) Zhang, Ming Rong a,b,c Haradahira, Terushi b Maeda, Jun a,c Okauchi, Takashi a,c Kawabe, Kouichi a Noguchi, Junko c Kida, Takayo a,c Suzuki, Kazutoshi b Suhara, Tetsuya a,b

a JAPAN SCIENCE AND TECHNOLOGY AGENCY (Japan)

b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (Japan)

c 141 0032 (Japan)

Author keywords

Autoradiography; Carbon 11; Dopamine D4 receptors; PET; Schizophrenia

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; 5 CHLORO 4 CYCLOPROPYLCARBONYLAMINO 2 METHOXY N [1 (3 METHOXYBENZYL) 3 PYRROLINDINYL]BENZAMIDE C 11; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE 5 RECEPTOR; KETANSERIN; LIGAND; N [2 [4 (4 CHLOROPHENYL)PIPERIZIN 1 YL]ETHYL] 3 METHOXYBENZAMIDE C 11; PHENOL DERIVATIVE; PRAZOSIN; RACLOPRIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG; YM 50001;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN CORTEX; BRAIN SLICE; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DISTRIBUTION; DRUG PURIFICATION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MALE; METHYLATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RAT; RECEPTOR AFFINITY; RECEPTOR DENSITY; RHESUS MONKEY; TISSUE DISTRIBUTION;

ANIMALS; BENZAMIDES; BRAIN; DOPAMINE ANTAGONISTS; INJECTIONS, INTRAVENOUS; LIGANDS; MACACA MULATTA; MALE; PIPERAZINES; RADIOISOTOPES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036164437 PISSN: 09698051 EISSN: None Source Type: Journal
DOI: 10.1016/S0969-8051(01)00301-8 Document Type: Article

Times cited : (28)

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