-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery M K, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391 (6669): 806-811
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
2
-
-
0036532120
-
RNAi; nature abhors a double-strand
-
Hutvagner G, Zamore P D. RNAi; nature abhors a double-strand. Curr Opin Gene Devel, 2002, 12 (2): 225-232
-
(2002)
Curr Opin Gene Devel
, vol.12
, Issue.2
, pp. 225-232
-
-
Hutvagner, G.1
Zamore, P.D.2
-
3
-
-
0036773703
-
SiRNA: A guide for RNA silencing
-
Ramaswamy G, Slack F J. SiRNA: A guide for RNA silencing. Chem Biol, 2002, 9 (10): 1053-1055
-
(2002)
Chem Biol
, vol.9
, Issue.10
, pp. 1053-1055
-
-
Ramaswamy, G.1
Slack, F.J.2
-
4
-
-
0037062951
-
RNA interference
-
Hannon G J. RNA interference. Nature, 2002, 418 (6894): 244 -251
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 244-251
-
-
Hannon, G.J.1
-
5
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S M, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 2001, 411 (6836): 494-498
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
6
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
MucManus M T, Sharp P A. Gene silencing in mammals by small interfering RNAs. Nature Reviews Genetics, 2002, 3 (10): 737-746
-
(2002)
Nature Reviews Genetics
, vol.3
, Issue.10
, pp. 737-746
-
-
MucManus, M.T.1
Sharp, P.A.2
-
7
-
-
0036742715
-
Applications of antisense and siRNAs during preclinical drug development
-
Thompson J D. Applications of antisense and siRNAs during preclinical drug development. Drugdiscovery Today, 2002, 7 (17): 912-917
-
(2002)
Drugdiscovery Today
, vol.7
, Issue.17
, pp. 912-917
-
-
Thompson, J.D.1
-
8
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents
-
Vickers T A, Koo S, Frank Bennett C, et al. Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. J Biol Chem, 2003, 278 (9): 7108-7118
-
(2003)
J Biol Chem
, vol.278
, Issue.9
, pp. 7108-7118
-
-
Vickers, T.A.1
Koo, S.2
Frank Bennett, C.3
-
9
-
-
0037107886
-
RNAi: Gene-silencng in therapeutic intervention
-
Shuey D J, McCallus D E, Giordano T. RNAi: gene-silencng in therapeutic intervention. Drugdiscovery Today, 2002 , 7 (20): 1040-1046
-
(2002)
Drugdiscovery Today
, vol.7
, Issue.20
, pp. 1040-1046
-
-
Shuey, D.J.1
McCallus, D.E.2
Giordano, T.3
-
10
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge A J, PebernaRd S, Ducraux A, et al. Induction of an interferon response by RNAi vectors in mammalian cells. Nature Genetics, 2003, 34 (7): 263-264
-
(2003)
Nature Genetics
, vol.34
, Issue.7
, pp. 263-264
-
-
Bridge, A.J.1
PebernaRd, S.2
Ducraux, A.3
-
11
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
Yu J Y, DeRuiter S L, Turner D L. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA, 2002, 99 (9): 6047-6052
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.9
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
12
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
Yang D, Buchholz F, Huang Z, et al. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci USA, 2002, 99 (15): 9942-99477
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.15
, pp. 9942-99477
-
-
Yang, D.1
Buchholz, F.2
Huang, Z.3
-
13
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G, Soohoo C, Affar E B, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA, 2002, 99 (8): 5515-5520
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.8
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affar, E.B.3
-
14
-
-
0036847965
-
Functional siRNA expression from transfected PCR products
-
Castanotto D, Li H, Rossi J J. Functional siRNA expression from transfected PCR products. RNA, 2002, 8 (11): 1454-1460
-
(2002)
RNA
, vol.8
, Issue.11
, pp. 1454-1460
-
-
Castanotto, D.1
Li, H.2
Rossi, J.J.3
-
15
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda M, Fuchs U, Wossmann W, et al. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene, 2002, 21 (37): 5716-5724
-
(2002)
Oncogene
, vol.21
, Issue.37
, pp. 5716-5724
-
-
Wilda, M.1
Fuchs, U.2
Wossmann, W.3
-
16
-
-
0037441756
-
Specific inhibition of bcr-abl gene expression by small interfering RNA
-
Scherr M, Battmer K, Winkler T, et al. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood, 2003, 101 (4): 1566-1569
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1566-1569
-
-
Scherr, M.1
Battmer, K.2
Winkler, T.3
-
17
-
-
0141790842
-
Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571)
-
Wohlbold L, Kuip H, Miething C, et al. Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571). Blood, 2003, 102 (6): 2236-2239
-
(2003)
Blood
, vol.102
, Issue.6
, pp. 2236-2239
-
-
Wohlbold, L.1
Kuip, H.2
Miething, C.3
-
18
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann M T, Fridman J S, Zilfou J T, et al. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat Genetics, 2003, 33 (3): 396-400
-
(2003)
Nat Genetics
, vol.33
, Issue.3
, pp. 396-400
-
-
Hemann, M.T.1
Fridman, J.S.2
Zilfou, J.T.3
-
19
-
-
0038756470
-
Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma1
-
Ramos-Nino M E, Scapoli L, Martinelli M, et al. Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma1. Cancer Res, 2003, 63 (13): 3539-3545
-
(2003)
Cancer Res
, vol.63
, Issue.13
, pp. 3539-3545
-
-
Ramos-Nino, M.E.1
Scapoli, L.2
Martinelli, M.3
-
20
-
-
0037026601
-
Selective silencing of viral gene expression in HPV-positive humane cervical carcinoma cells trested with siRNA, a primer of RNA interference
-
Jiang M, Milner J. Selective silencing of viral gene expression in HPV-positive humane cervical carcinoma cells trested with siRNA, a primer of RNA interference. Oncogene, 2002, 21 (39): 6041-6048
-
(2002)
Oncogene
, vol.21
, Issue.39
, pp. 6041-6048
-
-
Jiang, M.1
Milner, J.2
-
21
-
-
0142061975
-
Use of RNA interference to inhibit integrin (α6β4)-mediated invasion and migration of breast carcinoma cells
-
Lipscomb E A, Dugan A S, Rabinovitz I, et al. Use of RNA interference to inhibit integrin (α6β4)-mediated invasion and migration of breast carcinoma cells. Clinical Experimental Metastasis, 2003, 20 (3): 569-576
-
(2003)
Clinical Experimental Metastasis
, vol.20
, Issue.3
, pp. 569-576
-
-
Lipscomb, E.A.1
Dugan, A.S.2
Rabinovitz, I.3
-
22
-
-
0042941765
-
Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
-
Chen Y C, Stamatoyannopoulos G, Song C Z. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res, 2003, 63 (7): 4801-4804
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 4801-4804
-
-
Chen, Y.C.1
Stamatoyannopoulos, G.2
Song, C.Z.3
-
23
-
-
0038408486
-
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion
-
Li T L, Hui C C, Lien C C, et al. Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Cancer Res, 2003, 63 (6): 3069-3072
-
(2003)
Cancer Res
, vol.63
, Issue.6
, pp. 3069-3072
-
-
Li, T.L.1
Hui, C.C.2
Lien, C.C.3
-
24
-
-
0038392762
-
Questioning the role of checkpoint kinase 2 in the p53 DNA damage response
-
Ahn J, Urist M, Prives C. Questioning the role of checkpoint kinase 2 in the p53 DNA damage response. J Biol Chem, 2003, 278 (23): 20480-20489
-
(2003)
J Biol Chem
, vol.278
, Issue.23
, pp. 20480-20489
-
-
Ahn, J.1
Urist, M.2
Prives, C.3
-
25
-
-
0037456995
-
Modulation of p53 and p73 levels by cyclin G: Implication of a negative feedback regulation
-
Ohtsuka T, Ryu H, Minamishima Y A, et al. Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation. Oncogene, 2003, 22 (11): 1678-1687
-
(2003)
Oncogene
, vol.22
, Issue.11
, pp. 1678-1687
-
-
Ohtsuka, T.1
Ryu, H.2
Minamishima, Y.A.3
-
26
-
-
0037462796
-
Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
-
Yoon H S, Chen X M, Yang V W. Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J Biol Chem, 2003, 278 (4): 2101-2105
-
(2003)
J Biol Chem
, vol.278
, Issue.4
, pp. 2101-2105
-
-
Yoon, H.S.1
Chen, X.M.2
Yang, V.W.3
-
27
-
-
0037112212
-
53BP1, a mediator of the DNA damage checkpoint
-
Wang B, Matsuoka S, Carpenter P B, et al. 53BP1, a mediator of the DNA damage checkpoint. Science, 2002, 298 (5597): 1435 -1438
-
(2002)
Science
, vol.298
, Issue.5597
, pp. 1435-1438
-
-
Wang, B.1
Matsuoka, S.2
Carpenter, P.B.3
-
28
-
-
0036645678
-
Kip1 and regulates cell cycle progression
-
Kip1 and regulates cell cycle progression. EMBO J, 2002, 21 (13): 3390-3401
-
(2002)
EMBO J
, vol.21
, Issue.13
, pp. 3390-3401
-
-
Boehm, M.1
Yoshimoto, T.2
Crook, M.F.3
-
29
-
-
0037193461
-
Human Speedy: A novel cell cycle regulator that enhances proliferation through activation of Cdk2
-
Porter L A, Dellinger R W, Tynan J A, et al. Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. J Cell Biol, 2002, 157 (3): 357-366
-
(2002)
J Cell Biol
, vol.157
, Issue.3
, pp. 357-366
-
-
Porter, L.A.1
Dellinger, R.W.2
Tynan, J.A.3
-
30
-
-
0036841720
-
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases
-
Shu X, Wu W, Mosteller R D, et al. Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol Cell Biol, 2002, 22 (22): 7758-7768
-
(2002)
Mol Cell Biol
, vol.22
, Issue.22
, pp. 7758-7768
-
-
Shu, X.1
Wu, W.2
Mosteller, R.D.3
-
31
-
-
0141613693
-
SiRNA-mediated antitumorigenesis for drug target validation and therapeutics
-
Lu P Y, Xie F Y, Woodle M C, et al. siRNA-mediated antitumorigenesis for drug target validation and therapeutics. Curr Opin Mol Ther, 2003, 5 (3): 225-234
-
(2003)
Curr Opin Mol Ther
, vol.5
, Issue.3
, pp. 225-234
-
-
Lu, P.Y.1
Xie, F.Y.2
Woodle, M.C.3
-
32
-
-
0242551656
-
Activation of the Wnt pathway in non-small cell lung cancer: Evidence of dishevelled overexpression
-
Uematsu K, He B, You L, et al. Activation of the Wnt pathway in non-small cell lung cancer: evidence of dishevelled overexpression. Oncogene, 2003, 22 (46): 7218-7221
-
(2003)
Oncogene
, vol.22
, Issue.46
, pp. 7218-7221
-
-
Uematsu, K.1
He, B.2
You, L.3
-
33
-
-
0036432860
-
Subtype- and species-specie knockdown of PKC using short interfering RNA
-
Irie N, Sakai N, Ueyama T, et al. Subtype- and species-specie knockdown of PKC using short interfering RNA. Biochem Biophys Res Commun, 2002, 298 (5): 738-743
-
(2002)
Biochem Biophys Res Commun
, vol.298
, Issue.5
, pp. 738-743
-
-
Irie, N.1
Sakai, N.2
Ueyama, T.3
-
34
-
-
0037132736
-
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
-
Spankuch-Schmitt B, Bereniter-Hahn J, Kaufmann M, et al. Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells. J Nati Cancer Inst, 2002, 94 (24): 1863-1877
-
(2002)
J Nati Cancer Inst
, vol.94
, Issue.24
, pp. 1863-1877
-
-
Spankuch-Schmitt, B.1
Bereniter-Hahn, J.2
Kaufmann, M.3
-
35
-
-
0037440004
-
Functional studies of the PI (3) -kinase signaling pathway employing synthetic and expressed siRNA
-
Czauderna F, Fechtner M, Aygun H, et al. Functional studies of the PI (3) -kinase signaling pathway employing synthetic and expressed siRNA. Nucleic Acids Res, 2003, 31 (2): 670-682
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.2
, pp. 670-682
-
-
Czauderna, F.1
Fechtner, M.2
Aygun, H.3
-
36
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P, Opitz-Araya X, Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science, 2002, 279 (5585): 1352-1354
-
(2002)
Science
, vol.279
, Issue.5585
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
37
-
-
0037020234
-
Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and fortilin, the potential role of MCL as a fortilin chaperone
-
Zhang D, Li F, Weidner D, et al. Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and fortilin, the potential role of MCL as a fortilin chaperone. J Biol Chem, 2002, 277 (40): 37430-37438
-
(2002)
J Biol Chem
, vol.277
, Issue.40
, pp. 37430-37438
-
-
Zhang, D.1
Li, F.2
Weidner, D.3
-
38
-
-
0037380598
-
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
-
Jiang M, Milner J. Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells. Genes Dev, 2003, 17 (7): 832-837
-
(2003)
Genes Dev
, vol.17
, Issue.7
, pp. 832-837
-
-
Jiang, M.1
Milner, J.2
-
39
-
-
0037329372
-
RNA interfering is a functionl pathway with therapeutic potential in human myeloid leukemia cell lines
-
Cioca D P, Aoki Y, Kiyosawa K. RNA interfering is a functionl pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer Gene Therapy, 2003, 10 (3): 125-133
-
(2003)
Cancer Gene Therapy
, vol.10
, Issue.3
, pp. 125-133
-
-
Cioca, D.P.1
Aoki, Y.2
Kiyosawa, K.3
-
40
-
-
0037380839
-
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein ) restores sensitivity to multidrug-resistant cancer cells
-
Wu H, Hait W N, Yang J M. Small interfering RNA-induced suppression of MDR1 (P-glycoprotein ) restores sensitivity to multidrug-resistant cancer cells. Cancer Res, 2003, 63 (7): 1515 -1519
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1515-1519
-
-
Wu, H.1
Hait, W.N.2
Yang, J.M.3
-
41
-
-
0037382008
-
Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors
-
Collis S J, Swartz M J, Nelson W J, et al. Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. Cancer Res, 2003, 63 (7): 1550-1554
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1550-1554
-
-
Collis, S.J.1
Swartz, M.J.2
Nelson, W.J.3
-
42
-
-
0035542769
-
RNAi is antagonized by A→1 hyper-editing
-
Scadden A D, Smith C W. RNAi is antagonized by A→1 hyper-editing. EMBO Rep, 2001, 2 (12): 1107-1111
-
(2001)
EMBO Rep
, vol.2
, Issue.12
, pp. 1107-1111
-
-
Scadden, A.D.1
Smith, C.W.2
|