The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis

Toxicology and Applied Pharmacology

Volumn 198, Issue 3, 2004, Pages 385-393

  Yamanaka, Kenzo ^a   Kato, Koichi ^a   Mizoi, Mutsumi ^a   An, Yan ^a   Takabayashi, Fumiyo ^b   Nakano, Masayuki ^c   Hoshino, Mikio ^d,e   Okada, Shoji ^b  

^a NIHON UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION CHIBA MEDICAL CENTER   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

8 Oxo 2 deoxyguanosine; Dimethylarsenic peroxy radical; Dimethylarsenic radical; Dimethylarsine; Dimethylarsinic acid; Dimethylated arsenic peroxide; Micronucleus; Thymine glycol; Trivalent dimethylated arsenic; Tumor promotion

Indexed keywords

ARSENIC; CACODYLIC ACID; DNA; HYDROGEN PEROXIDE; HYDROXYL GROUP; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHEMICAL REACTION; CONTROLLED STUDY; FEMALE; GENOTOXICITY; LUNG CARCINOGENESIS; MALE; METHYLATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN;

ANIMALS; CACODYLIC ACID; CARCINOGENS; HERBICIDES; MICE; MICE, INBRED ICR; MUTAGENS; OXIDATIVE STRESS; THYMINE;

FRAXINUS;

EID: 3242760758     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2003.10.025     Document Type: Article

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