Dimethylarsinic acid effects on DNA damage and oxidative stress related biochemical parameters in B6C3F1 mice

Cancer Letters

Volumn 139, Issue 2, 1999, Pages 129-135

  Ahmad, S ^a   Anderson, W L ^a   Kitchin, K T ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

B6C3F1 mice; Dimethylarsinic acid; DNA damage; Oxidative stress

Indexed keywords

CACODYLIC ACID; CYTOCHROME P450; GLUTATHIONE; GLUTATHIONE DISULFIDE; ORNITHINE DECARBOXYLASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; CACODYLIC ACID; CARCINOGENS; CROSSES, GENETIC; CYTOCHROME P-450 ENZYME SYSTEM; DNA DAMAGE; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HERBICIDES; LIVER; LUNG; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; ORNITHINE DECARBOXYLASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS;

EID: 0032939648     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00022-1     Document Type: Article

References (44)

1. Bates M.N., Smith A.H., Hopenhayn R.C. Arsenic ingestion and internal cancers a review. Am. J. Epidemiol. 135:1992;462-476.
2. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. 1992;Van Nostrand Reinhold, New York.
3. Murai T., Iwata H., Otoshi T., Endo G., Horiguchi S., Fukushima S. Renal lesions induced in F344/DuCrj rats by 4-weeks oral administration of dimethylarsinic acid. Toxicol. Lett. 66:1993;53-61.
4. US EPA, US EPA peer review document on DMA, US EPA Peer Rev. (1994) 1-20.
5. Yamanaka K., Ohtsubo K., Hasegawa A., Hayashi H., Ohji H., Kanisawa M., Okada S. Exposure to dimethylarsinic acid, a main metabolise of inorganic arsenics, strongly promotes tumorigenesis initiated by 4-nitroquinoline 1-oxide in the lungs of mice. Carcinogenesis. 17:1996;767-770.
6. Yamamoto S., Konishi Y., Matsuda T., Murai T., Shibata M.A., Matsui Y.I., Otani S., Kuroda K., Endo G., Fukushima S. Cancer induction by an organic arsenic compound, dimethylarsinic acid (cacodylic acid), in F344/DuCrj rats after pretreatment with five carcinogens. Cancer Res. 55:1995;1271-1276.
7. Vahter M., Marafante E., Dencker L. Tissue distribution and retention of 74As-dimethylarsinic acid in mice and rats. Arch. Environ. Contam. Toxicol. 13:1984;259-264.
8. Brown J.L., Kitchin K.T., George M. Dimethylarsinic acid treatment alters six different rat biochemical parameters: relevance to arsenic carcinogenesis. Teratog. Carcinog. Mutag. 17:1997;71-84.
9. Yamanaka K., Okada S. Induction of lung-specific DNA damage by metabolically methylated arsenics via the production of free radicals. Environ. Health Perspect. 10(Suppl. 3):1994;37-40.
10. Yamanaka K., Hasegawa A., Sawamura R., Okada S. Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolise of inorganic arsenic, in mice, Toxicol. Appl. Pharmacol. 108:1991;205-213.
11. Wanibuchi H., Hori T., Meenakshi V., Ichihara T., Yamamoto S., Yano Y., Otani S., Nakee D., Konishi Y., Fukushima S. Promotion of rat hepatocarcinogenesis by dimethylarsinic acid: association with elevated ornithine decarboxylase activity and formation of 8-hydroxydeoxyquanosine in the liver. Jpn. J. Cancer Res. 88:1997;1149-1154.
12. Hayashi H., Kanisawa M., Yamanaka K., Ito T., Udaka N., Ohji H., Okudela K., Okada S., Kitamura H. Dimethylarsinic acid, a main metabolite of inorganic arsenics, has tumorigenicity and progression effects in the pulmonary tumors of aj mice. Cancer Lett. 125:1998;83-88.
13. Dong J.T., Luo X.M. Arsenic-induced DNA-strand breaks associated with DNA protein crosslinks in human fetal lung fibroblasts. Mutat. Res. 302:1993;97-102.
14. Endo G., Kuroda K., Okamoto A., Horigachi S. Dimethylarsenic acid induces tetraploids in Chinese hamster cells. Bull. Environ. Contam. Toxicol. 43:1992;131-137.
15. Tezuka M., Hanioka K., Yamanaka K., Okada S. Gene damage induced in human alveolar type II (L-132) cells by exposure to dimethylarsinic acid. Biochem. Biophys. Res. Commun. 191:1993;1178-1183.
16. Yamanaka K., Tezuka M., Kato K., Hasegawa A., Okada S. Crosslink formation between DNA and nuclear proteins by in vivo and in vitro exposure of cells to dimethylarsinic acid. Biochem. Biophys. Res. Commun. 191:1993;1184-1191.
17. Kato K., Hayashi H., Hasegawa A., Yamanaka K., Okada S. Damage induced in cultured human alveolar (L132) cells by exposure to dimethylarsinic acid. Environ. Health Perspect. 102:(Suppl. 3):1994;285-288.
18. Yamanaka K., Hayashi H., Kato K., Hasegawa A., Okada S. Involvement of preferential formation of apurinic/apyrimidinic sites in dimethylarsenic-induced DNA strand breaks and DNA-protein crosslinks in cultured alveolar epithelial cells. Biochem. Biophys. Res. Commun. 207:1995;244-249.
19. Yamanaka K., Hayashi H., Kato K., Hasegawa A., Oku N., Okada S. single-strand breaks in I-132 cells resulting from inhibition of repair polymerization shortly after exposure to dimethylarsinic acid. Biol. Pharm. Bull. 20:1997;163-167.
20. Ochi T., Nakajima F., Sakurai T., Kaise T., Oya-Ohta Y. Dimethylarsinic acid causes apoptosis in HL60 cells via interaction with glutathione. Arch. Toxicol. 7:1996;815-821.
21. National Research Council, Report on the Medical and Biological Effects of Environmental Pollutants, Arsenic, National Academy of Sciences, Washington, DC, 1977.
22. Odanaka Y., Matano O. Biomethylation of inorganic arsenic by the rat and some laboratory animals. Bull. Environ. Contam. Toxicol. 24:1980;452-459.
23. Anderson M. Packer L., Cadenas E. Handbook of Antioxidants. 1997;321-328 Marcel Dekker, New York.
24. Russell D.H. Ornithine decarboxylase: a key regulatory enzyme in normal and neoplastic growth. Drug Metab. Rev. 16:1985;1-88.
25. O'Brien T.G. The induction of ornithine decarboxylase as an early, possible obligatory, event in mouse skin carcinogenesis, Cancer Res. 36:1976;2644-2653.
26. Schulte-Hermann R. Tumor promotion in the liver. Arch. Toxicol. 57:1985;147-158.
27. Kitchin K.T., Brown J.L., Kulkarni A.P. Predictive assay for rodent carcinogenicity using in vivo biochemical parameters: operational characteristics and complementarity. Mutat. Res. 266:1992;253-272.
28. Kitchin K.T., Brown J.L., Kulkarni A.P. Predicting rodent carcinogenicity by in vitro biochemical parameters. Environ. Carcinogenesis Ecotoxicol. Rev. Part C J. Environ. Sci. Health C. 12:1994;63-88.
29. Hissin P.J., Hilf R. fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74:1976;214-226.
30. Yamanaka K., Hasegawa A., Sawamura R., Okada S. strand breaks in mammalian tissues induced by methylarsenics. Biol. Trace Elem. Res. 21:1989;413-417.
31. Oya-Ohta Y., Kaise T., Ochi T. Induction of chromosomal aberrations in cultured human fibroblasts by inorganic and organic arsenic compounds and the different roles of glutathione in such induction. Mutat. Res. 357:1996;123-129.
32. Delnomdedieu M., Basti M.M., Otvos J.D., Thomas D.J. Reduction and binding of arsenate and dimethylarsinate by glutathione: a magnetic resonance study. Chem. Biol. Interact. 90:1994;139-155.
33. Sakurai T., Kaise T., Matsubara C. Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms. Chem. Res. Toxicol. 11:1998;273-283.
34. Delnomdedieu M., Styblo M., Thomas D.J. Time dependence of accumulation and binding of inorganic and organic arsenic species in rabbit erythrocytes. Chem. Biol. Interact. 98:1995;69-83.
35. Brown J.L., Kitchin K.T. Arsenite, but not cadmium, induces ornithine decarboxylase and heme oxygenase activity in rat liver - relevance to arsenic carcinogenesis, Cancer Lett. 98:1996;227-231.
36. Hughes M.F., Kenyon E.M. Dose-dependent effects on the disposition of monomethylarsonic acid and dimethylarsinic acid in the mouse after intravenous administration. J. Toxicol. Environ. Health Part A. 53:1998;95-112.
37. Nordenson I., Beckman L. Is the genotoxic effect of arsenic mediated by oxygen free radicals? Hum. Hered. 41:1991;71-73.
38. Wang T.S., Huang H. Active oxygen species are involved in the induction of micronuclei by arsenite in XRS5 cells. Mutegenesis. 9:1994;253-257.
39. Wang T.S., Kuo C.F., Jan K.Y., Huang H.M. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species. J. Cell. Physiol. 169:1996;256-268.
40. Lee T.C., Ho I.C. Modulation of cellular antioxidant defense activities by sodium arsenite in human fibroblasts. Arch. Toxicol. 69:1995;498-504.
41. Barchowsky A., Dudek E.J., Treadwell M.D., Wetterharn K.E. Arsenic induces oxidant stress and NF-kappa-B activation in cultured aortic endothelial cells. Free Radic. Biol. Med. 21:1996;783-790.
42. Lynn S., Shiung J.N., Gurr J.R., Jan K.Y. Arsenite stimulates poly(Adp-ribosvlation) by generation of nitric oxide. Free Radic. Biol. Med. 24:1998;442-449.
43. Eisenstein R.S., Garcia M.D., Pettingell W., Munro H.N. Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc. Natl. Acad. Sci. USA. 88:1991;688-692.
44. Guzzo A., Karatzios C., Diorio C., Dubow M.S. Metallothionein-II and ferritin H mRNA levels are increased in arsenite-exposed HeLa cells. Biochem. Biophys. Res. Commun. 205:1994;590-595.