Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: Evidence for genetic modifiers in the 5-HT-mediated regulation of GABAA receptors

Journal of Neuroscience

Volumn 24, Issue 28, 2004, Pages 6343-6351

  Bailey, Sarah J ^a,b   Toth, Miklos ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Anxiety; Benzodiazepine; GABA; Mouse; Neurotransmitter; Serotonin

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; BENZODIAZEPINE; DIAZEPAM; RECEPTOR SUBUNIT; SEROTONIN; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY DISORDER; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA MODIFICATION; DRUG RECEPTOR BINDING; DRUG SENSITIVITY; GENETIC TRANSCRIPTION; HYBRID; MOUSE; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSYCHOPHARMACOLOGY; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; SEROTONINERGIC TRANSMISSION;

AMYGDALA; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; CROSSES, GENETIC; DIAZEPAM; DRUG RESISTANCE; EPISTASIS, GENETIC; FRONTAL LOBE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAZE LEARNING; MICE; MICE, INBRED C57BL; PROTEIN INTERACTION MAPPING; PROTEIN SUBUNITS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, GABA-A; RNA, MESSENGER;

EID: 3242703144     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0563-04.2004     Document Type: Article

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