Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position

Peptides

Volumn 27, Issue 2, 2006, Pages 472-481

  Grieco, Paolo ^b   Cai, Minying ^a   Mayorov, Alexander V ^a   Trivedi, Dev ^a   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cyclic peptide lactams; Melanotropin receptors; Melanotropins; N Terminal aromatic amino acid substitution; Receptor selectivity; Structure activity

Indexed keywords

AMINO ACID; MELANOCORTIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BIOLOGICAL ACTIVITY; HORMONE SYNTHESIS; HUMAN; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; CELLS, CULTURED; COMPUTER SIMULATION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MELANOCYTE-STIMULATING HORMONES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, MELANOCORTIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 31544439367     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2005.01.032     Document Type: Article

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