메뉴 건너뛰기




Volumn 94, Issue 2, 2006, Pages 323-332

Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome

Author keywords

AML; GRAF; MDS; Promoter methylation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; TRICHOSTATIN A;

EID: 31444455401     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602939     Document Type: Article
Times cited : (24)

References (44)
  • 1
    • 0032403946 scopus 로고    scopus 로고
    • Repression of the mouse M-lysozyme gene involves both hindrance of enhancer factor binding to the methylated enhancer and histone deacetylation
    • Ammerpohl O, Schmitz A, Steinmüller L, Renkawitz R (1998) Repression of the mouse M-lysozyme gene involves both hindrance of enhancer factor binding to the methylated enhancer and histone deacetylation. Nucleic Acids Res 26: 5256-5260
    • (1998) Nucleic Acids Res , vol.26 , pp. 5256-5260
    • Ammerpohl, O.1    Schmitz, A.2    Steinmüller, L.3    Renkawitz, R.4
  • 2
    • 0030728855 scopus 로고    scopus 로고
    • Complex protein binding to the mouse M-lysozyme gene downstream enhancer involves single-stranded DNA binding
    • Ammerpohl O, Short ML, Asbrand C, Schmitz A, Renkawitz R (1997) Complex protein binding to the mouse M-lysozyme gene downstream enhancer involves single-stranded DNA binding. Gene 200: 75-84
    • (1997) Gene , vol.200 , pp. 75-84
    • Ammerpohl, O.1    Short, M.L.2    Asbrand, C.3    Schmitz, A.4    Renkawitz, R.5
  • 3
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • Baylin SB, Herman JG (2000) DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 16: 168-174
    • (2000) Trends Genet , vol.16 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 4
    • 0025944899 scopus 로고
    • DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV- 1 long terminal repeat cognate DNA motifs
    • Bednarik DP, Duckett C, Kim SU, Perez VL, Griffis K, Guenthner PC, Folks TM (1991) DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV- 1 long terminal repeat cognate DNA motifs. New Biol 3: 969-976
    • (1991) New Biol , vol.3 , pp. 969-976
    • Bednarik, D.P.1    Duckett, C.2    Kim, S.U.3    Perez, V.L.4    Griffis, K.5    Guenthner, P.C.6    Folks, T.M.7
  • 5
    • 0024830846 scopus 로고
    • Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: Effects on transcription in vivo and on factor binding in vitro
    • Ben Hattar J, Beard P, Jiricny J (1989) Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: effects on transcription in vivo and on factor binding in vitro. Nucleic Acids Res 17: 10179-10190
    • (1989) Nucleic Acids Res , vol.17 , pp. 10179-10190
    • Ben Hattar, J.1    Beard, P.2    Jiricny, J.3
  • 8
    • 0025294471 scopus 로고
    • CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
    • Comb M, Goodman HM (1990) CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res 18: 3975-3982
    • (1990) Nucleic Acids Res , vol.18 , pp. 3975-3982
    • Comb, M.1    Goodman, H.M.2
  • 9
    • 0020032366 scopus 로고
    • Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2′- deoxycytidine
    • Creusot F, Acs G, Christman JK (1982) Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2′-deoxycytidine. J Biol Chem 257: 2041-2048
    • (1982) J Biol Chem , vol.257 , pp. 2041-2048
    • Creusot, F.1    Acs, G.2    Christman, J.K.3
  • 10
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 11
    • 0030843274 scopus 로고    scopus 로고
    • Methylation of the BRCA1 gene in sporadic breast cancer
    • Dobrovic A, Simpfendorfer D (1997) Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res 57: 3347-3350
    • (1997) Cancer Res , vol.57 , pp. 3347-3350
    • Dobrovic, A.1    Simpfendorfer, D.2
  • 12
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429: 457-463
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 14
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden M, Frommer M (1987) CpG islands in vertebrate genomes. J Mol Biol 196: 261-282
    • (1987) J Mol Biol , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 15
    • 0029033949 scopus 로고
    • CpG methylation and the binding of YY1 and ETS proteins to the Surf-1/Surf-2 bidirectional promoter
    • Gaston K, Fried M (1995) CpG methylation and the binding of YY1 and ETS proteins to the Surf-1/Surf-2 bidirectional promoter. Gene 157: 257-259
    • (1995) Gene , vol.157 , pp. 257-259
    • Gaston, K.1    Fried, M.2
  • 16
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, Nguyen T, Beart RW, Van Tornout JM, Jones PA (1995) Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res 55: 4531-4535
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornout, J.M.6    Jones, P.A.7
  • 17
    • 0030868694 scopus 로고    scopus 로고
    • Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation
    • Graff JR, Herman JG, Myohanen S, Baylin SB, Vertino PM (1997) Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J Biol Chem 272: 22322-22329
    • (1997) J Biol Chem , vol.272 , pp. 22322-22329
    • Graff, J.R.1    Herman, J.G.2    Myohanen, S.3    Baylin, S.B.4    Vertino, P.M.5
  • 18
    • 0032731581 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes in cancer
    • Herman JG (1999) Hypermethylation of tumor suppressor genes in cancer. Semin Cancer Biol 9: 359-367
    • (1999) Semin Cancer Biol , vol.9 , pp. 359-367
    • Herman, J.G.1
  • 19
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 23
    • 0029955660 scopus 로고    scopus 로고
    • An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
    • Hildebrand JD, Taylor JM, Parsons JT (1996) An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 16: 3169-3178
    • (1996) Mol Cell Biol , vol.16 , pp. 3169-3178
    • Hildebrand, J.D.1    Taylor, J.M.2    Parsons, J.T.3
  • 24
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga SM, Schaffner W (1989) CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev 3: 612-619
    • (1989) Genes Dev , vol.3 , pp. 612-619
    • Iguchi-Ariga, S.M.1    Schaffner, W.2
  • 26
    • 0028151343 scopus 로고
    • Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
    • Juttermann R, Li E, Jaenisch R (1994) Toxicity of 5-aza-2′- deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 91: 11797-11801
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11797-11801
    • Juttermann, R.1    Li, E.2    Jaenisch, R.3
  • 27
    • 13244269877 scopus 로고    scopus 로고
    • Radio- and chemo-sensitization of human erythroleukemic K562 cells by the histone deacetylase inhibitor trichostatin A
    • Karagiannis TC, Smith AJ, El OA (2004) Radio- and chemo-sensitization of human erythroleukemic K562 cells by the histone deacetylase inhibitor trichostatin A. Hell J Nucl Med 7: 184-191
    • (2004) Hell J Nucl Med , vol.7 , pp. 184-191
    • Karagiannis, T.C.1    Smith, A.J.2    El, O.A.3
  • 28
    • 0038544192 scopus 로고    scopus 로고
    • Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents
    • Kim DH, Kim M, Kwon HJ (2003) Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. J Biochem Mol Biol 36: 110-119
    • (2003) J Biochem Mol Biol , vol.36 , pp. 110-119
    • Kim, D.H.1    Kim, M.2    Kwon, H.J.3
  • 29
    • 0023191227 scopus 로고
    • Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control
    • Kovesdi I, Reichel R, Nevins JR (1987) Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control. Proc Natl Acad Sci USA 84: 2180-2184
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2180-2184
    • Kovesdi, I.1    Reichel, R.2    Nevins, J.R.3
  • 30
    • 2942566395 scopus 로고    scopus 로고
    • Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells
    • Liu ZJ, Zhang XB, Zhang Y, Yang X (2004) Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells. FEBS Lett 567: 327-332
    • (2004) FEBS Lett , vol.567 , pp. 327-332
    • Liu, Z.J.1    Zhang, X.B.2    Zhang, Y.3    Yang, X.4
  • 33
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
    • Marks PA, Richon VM, Rifkind RA (2000) Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 92: 1210-1216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 34
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki JR, Vincent PC, Clark SJ (1999) Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 59: 3730-3740
    • (1999) Cancer Res , vol.59 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 35
    • 0028874703 scopus 로고
    • Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding
    • Nickel J, Short ML, Schmitz A, Eggert M, Renkawitz R (1995) Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding. Nucleic Acids Res 23: 4785-4792
    • (1995) Nucleic Acids Res , vol.23 , pp. 4785-4792
    • Nickel, J.1    Short, M.L.2    Schmitz, A.3    Eggert, M.4    Renkawitz, R.5
  • 37
    • 8444251045 scopus 로고    scopus 로고
    • MLL/GRAF fusion in an infant acute monocytic leukemia (AML M5b) with a cytogenetically cryptic ins(5;11)(q31;q23q23)
    • Panagopoulos I, Kitagawa A, Isaksson M, Morse H, Mitelman F, Johansson B (2004) MLL/GRAF fusion in an infant acute monocytic leukemia (AML M5b) with a cytogenetically cryptic ins(5;11)(q31;q23q23). Genes Chromosomes Cancer 41: 400-404
    • (2004) Genes Chromosomes Cancer , vol.41 , pp. 400-404
    • Panagopoulos, I.1    Kitagawa, A.2    Isaksson, M.3    Morse, H.4    Mitelman, F.5    Johansson, B.6
  • 39
    • 0023835505 scopus 로고
    • A high-efficiency HeLa cell nuclear transcription extract
    • Shapiro DJ, Sharp PA, Wahli WW, Keller MJ (1988) A high-efficiency HeLa cell nuclear transcription extract. DNA 7: 47-55
    • (1988) DNA , vol.7 , pp. 47-55
    • Shapiro, D.J.1    Sharp, P.A.2    Wahli, W.W.3    Keller, M.J.4
  • 40
    • 0028566384 scopus 로고
    • Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction
    • Weiner MP, Costa GL, Schoettlin W, Cline J, Mathur E, Bauer JC (1994) Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction. Gene 151: 119-123
    • (1994) Gene , vol.151 , pp. 119-123
    • Weiner, M.P.1    Costa, G.L.2    Schoettlin, W.3    Cline, J.4    Mathur, E.5    Bauer, J.C.6
  • 41
    • 21744443965 scopus 로고    scopus 로고
    • Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5)
    • Wilda M, Perez AV, Bruch J, Woessmann W, Metzler M, Fuchs U, Borkhardt A (2005) Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5). Genes Chromosomes Cancer 43: 424-426
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 424-426
    • Wilda, M.1    Perez, A.V.2    Bruch, J.3    Woessmann, W.4    Metzler, M.5    Fuchs, U.6    Borkhardt, A.7
  • 42
    • 3142754272 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter
    • Yokota T, Matsuzaki Y, Miyazawa K, Zindy F, Roussel MF, Sakai T (2004) Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. Oncogene 23: 5340-5349
    • (2004) Oncogene , vol.23 , pp. 5340-5349
    • Yokota, T.1    Matsuzaki, Y.2    Miyazawa, K.3    Zindy, F.4    Roussel, M.F.5    Sakai, T.6
  • 44
    • 0037276902 scopus 로고    scopus 로고
    • The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells
    • Zhu WG, Otterson GA (2003) The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. Curr Med Chem Anti-Cancer Agents 3: 187-199
    • (2003) Curr Med Chem Anti-Cancer Agents , vol.3 , pp. 187-199
    • Zhu, W.G.1    Otterson, G.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.