Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5)

Genes Chromosomes and Cancer

Volumn 43, Issue 4, 2005, Pages 424-426

  Wilda, Monika ^b   Perez, Antje Vega ^b   Bruch, Jochen ^b   Woessmann, Wilhelm ^b   Metzler, Markus ^c   Fuchs, Uta ^a   Borkhardt, Arndt ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; CYTARABINE; ETOPOSIDE; IDARUBICIN; MITOXANTRONE; MIXED LINEAGE LEUKEMIA PROTEIN; TIOGUANINE;

ACUTE MONOCYTIC LEUKEMIA; ALLOGENEIC STEM CELL TRANSPLANTATION; CANCER CHEMOTHERAPY; CASE REPORT; CHROMOSOME 5Q; CHROMOSOME ANALYSIS; CLINICAL PROTOCOL; GAMMA IRRADIATION; GENE FUSION; GENE REARRANGEMENT; GRAF GENE; HUMAN; INFANT; LETTER; MALE; MINIMAL RESIDUAL DISEASE; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROGNOSIS; REMISSION; SKULL IRRADIATION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CYTARABINE; DNA-BINDING PROTEINS; ETOPOSIDE; GTPASE-ACTIVATING PROTEINS; HUMANS; IDARUBICIN; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; LEUKEMIA, MYELOCYTIC, ACUTE; MALE; MITOXANTRONE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASM, RESIDUAL; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENES; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 21744443965     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.20182     Document Type: Letter

References (5)

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2. Fuchs U, Rehkamp G, Haas OA, Slany R, Konig M, Bojesen S, Bohle RM, Damm-Welk C, Ludwig WD, Harboft J, Borkhardt A. 2001. The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. Proc Natl Acad Sci USA 98: 8756-8761.
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4. Panagopoulos I, Kitagawa A, Isaksson M, Morse H, Mitelman F, Johansson B. 2004. MLL/GRAF fusion in an infant acute monocytic leukemia (AML M5b) with a cytogenetically cryptic ins(5;11)(q31;q23q23). Genes Chromosomes Cancer 41: 400-404.
5. Taki T, Kano H, Taniwaki M, Sako M, Yanagisawa M, Hayashi Y. 1999. AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11) (q31;q13q23). Proc Natl Acad Sci USA 96:14535-14540.