메뉴 건너뛰기




Volumn 3, Issue 6, 2005, Pages 325-334

Methylation silencing of the Apaf-1 gene in acute leukemia

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; DNA METHYLTRANSFERASE 1; MESSENGER RNA; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR SP1;

EID: 21344462364     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-04-0105     Document Type: Article
Times cited : (72)

References (36)
  • 1
    • 2342459790 scopus 로고    scopus 로고
    • DNA damage-induced apoptosis
    • Norbury CJ, Zhivotovsky B. DNA damage-induced apoptosis. Oncogene 2004;23:2797-808.
    • (2004) Oncogene , vol.23 , pp. 2797-2808
    • Norbury, C.J.1    Zhivotovsky, B.2
  • 2
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997;90:405-13.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 3
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 4
    • 0032493870 scopus 로고    scopus 로고
    • Differential requirement for caspase 9 in apoptotic pathways in vivo
    • Hakem R, Hakem A, Duncan GS, et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 1998;94:339-52.
    • (1998) Cell , vol.94 , pp. 339-352
    • Hakem, R.1    Hakem, A.2    Duncan, G.S.3
  • 5
    • 0033515883 scopus 로고    scopus 로고
    • Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
    • Soengas MS, Alarcon RM, Yoshida H, et al. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 1999;284:156-9.
    • (1999) Science , vol.284 , pp. 156-159
    • Soengas, M.S.1    Alarcon, R.M.2    Yoshida, H.3
  • 6
    • 0035843169 scopus 로고    scopus 로고
    • Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
    • Soengas MS, Capodieci P, Polsky D, et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001;409:207-11.
    • (2001) Nature , vol.409 , pp. 207-211
    • Soengas, M.S.1    Capodieci, P.2    Polsky, D.3
  • 7
    • 0033623874 scopus 로고    scopus 로고
    • Genetic analysis of the APAF1 gene in male germ cell tumors
    • Bala S, Oliver H, Renault B, et al. Genetic analysis of the APAF1 gene in male germ cell tumors. Genes Chromosomes Cancer 2000;28:258-68.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 258-268
    • Bala, S.1    Oliver, H.2    Renault, B.3
  • 8
    • 0242667892 scopus 로고    scopus 로고
    • Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma
    • Watanabe T, Hirota Y, Arakawa Y, et al. Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma. Brain Pathol 2003;13: 431-9.
    • (2003) Brain Pathol , vol.13 , pp. 431-439
    • Watanabe, T.1    Hirota, Y.2    Arakawa, Y.3
  • 9
    • 0034055156 scopus 로고    scopus 로고
    • Frameshift mutations in Fas, Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype
    • Yamamoto H, Gil J, Schwartz SJ, Perucho M. Frameshift mutations in Fas, Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype. Cell Death Differ 2000;7:238-9.
    • (2000) Cell Death Differ , vol.7 , pp. 238-239
    • Yamamoto, H.1    Gil, J.2    Schwartz, S.J.3    Perucho, M.4
  • 10
    • 18644381327 scopus 로고    scopus 로고
    • Apaf-1 is a mediator of E2F-1-induced apoptosis
    • Furukawa Y, Nishimura N, Furukawa Y, et al. Apaf-1 is a mediator of E2F-1-induced apoptosis. J Biol Chem 2002;277:39760-8.
    • (2002) J Biol Chem , vol.277 , pp. 39760-39768
    • Furukawa, Y.1    Nishimura, N.2    Furukawa, Y.3
  • 11
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002;99:3740-5.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 12
    • 1642434054 scopus 로고    scopus 로고
    • Decitabine: Development of a DNA methyltransferase inhibitor for hematological malignancies
    • Lyons J, Bayar E, Fine G, et al. Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies. Curr Opin Investig Drugs 2003;4:1442-50.
    • (2003) Curr Opin Investig Drugs , vol.4 , pp. 1442-1450
    • Lyons, J.1    Bayar, E.2    Fine, G.3
  • 13
    • 0037461895 scopus 로고    scopus 로고
    • Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia
    • Fu W-N, Bert oni F, Kelsey SM, et al. Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia. Oncogene 2003;22:451-5.
    • (2003) Oncogene , vol.22 , pp. 451-455
    • Fu, W.-N.1    Bert Oni, F.2    Kelsey, S.M.3
  • 14
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T. The DNA methyltransferases of mammals. Hum Mol Genet 2000; 9:2395-402.
    • (2000) Hum Mol Genet , vol.9 , pp. 2395-2402
    • Bestor, T.1
  • 15
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992;69:915-26.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 16
  • 17
    • 4544223707 scopus 로고    scopus 로고
    • Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
    • Bourc'his D, Bestor TH. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 2004;431:96-9.
    • (2004) Nature , vol.431 , pp. 96-99
    • Bourc'His, D.1    Bestor, T.H.2
  • 18
    • 1542510618 scopus 로고    scopus 로고
    • Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma
    • Fujimoto A, Takeuchi H, Taback B, et al. Allelic imbalance of 12q22-23 associated with APAF-1 locus correlates with poor disease outcome in cutaneous melanoma. Cancer Res 2004;64:2245-50.
    • (2004) Cancer Res , vol.64 , pp. 2245-2250
    • Fujimoto, A.1    Takeuchi, H.2    Taback, B.3
  • 19
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor T, Laudano A, Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 1988;203:971-83.
    • (1988) J Mol Biol , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 20
    • 0036561649 scopus 로고    scopus 로고
    • Altered methylation patterns in cancer cell genomes: Cause or consequence?
    • Baylin S, Bestor TH. Altered methylation patterns in cancer cell genomes: cause or consequence? Cancer Cell 2002;1:299-305.
    • (2002) Cancer Cell , vol.1 , pp. 299-305
    • Baylin, S.1    Bestor, T.H.2
  • 21
    • 0242539836 scopus 로고    scopus 로고
    • Cancer epigenetics
    • Momparler RL. Cancer epigenetics. Oncogene 2003;22:6479-83.
    • (2003) Oncogene , vol.22 , pp. 6479-6483
    • Momparler, R.L.1
  • 22
    • 0344393732 scopus 로고    scopus 로고
    • Strategies for reversing drug resistance
    • Fojo T, Bates S. Strategies for reversing drug resistance. Oncogene 2003;22: 7512-23.
    • (2003) Oncogene , vol.22 , pp. 7512-7523
    • Fojo, T.1    Bates, S.2
  • 23
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki JR, Vincent PC, Clark SJ. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 1999;59:3730-40.
    • (1999) Cancer Res , vol.59 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 24
    • 0043163772 scopus 로고    scopus 로고
    • Aberrant gene promoter methylation in acute promyelocytic leukaemia: Profile and prognostic significance
    • Chim CS, Wong SY, Kwong YL. Aberrant gene promoter methylation in acute promyelocytic leukaemia: profile and prognostic significance. Br J Haematol 2003;122:571-8.
    • (2003) Br J Haematol , vol.122 , pp. 571-578
    • Chim, C.S.1    Wong, S.Y.2    Kwong, Y.L.3
  • 25
    • 0037625237 scopus 로고    scopus 로고
    • KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia
    • KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood 2003;101:4131-6.
    • (2003) Blood , vol.101 , pp. 4131-4136
    • Shen, L.1    Toyota, M.2    Kondo, Y.3
  • 26
    • 0036525616 scopus 로고    scopus 로고
    • 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21 (CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia
    • Roman-Gomez J, Castillejo JA, Jimenez A, et al. 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21 (CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia. Blood 2002;99:2291-6.
    • (2002) Blood , vol.99 , pp. 2291-2296
    • Roman-Gomez, J.1    Castillejo, J.A.2    Jimenez, A.3
  • 27
    • 0034554781 scopus 로고    scopus 로고
    • Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia
    • Svingen PA, Karp JE, Krajewski S, et al. Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood 2000;96:3922-31.
    • (2000) Blood , vol.96 , pp. 3922-3931
    • Svingen, P.A.1    Karp, J.E.2    Krajewski, S.3
  • 28
    • 0037224722 scopus 로고    scopus 로고
    • DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
    • Robert MF, Morin S, Beaulieu N, et al. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat Genet 2003; 33:61-5.
    • (2003) Nat Genet , vol.33 , pp. 61-65
    • Robert, M.F.1    Morin, S.2    Beaulieu, N.3
  • 29
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases, and cancer
    • Robertson KD. DNA methylation, methyltransferases, and cancer. Oncogene 2001;20:3139-55.
    • (2001) Oncogene , vol.20 , pp. 3139-3155
    • Robertson, K.D.1
  • 30
    • 0037598752 scopus 로고    scopus 로고
    • Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas
    • Saito Y, Kanai Y, Nakagawa T, et al. Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. Int J Cancer 2003;105:527-32.
    • (2003) Int J Cancer , vol.105 , pp. 527-532
    • Saito, Y.1    Kanai, Y.2    Nakagawa, T.3
  • 31
    • 0038527642 scopus 로고    scopus 로고
    • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
    • Di Croce L, Raker VA, Corsaro M, et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002;295:1079-82.
    • (2002) Science , vol.295 , pp. 1079-1082
    • Di Croce, L.1    Raker, V.A.2    Corsaro, M.3
  • 32
    • 0033781238 scopus 로고    scopus 로고
    • Lineage-specific regulation of cell cycle control gene expression during hematopoietic cell differentiation
    • Furukawa Y, Kikuchi J, Nakamura M, Iwase S, Yamada H, Matsuda M. Lineage-specific regulation of cell cycle control gene expression during hematopoietic cell differentiation. Br J Haematol 2000;110:663-73.
    • (2000) Br J Haematol , vol.110 , pp. 663-673
    • Furukawa, Y.1    Kikuchi, J.2    Nakamura, M.3    Iwase, S.4    Yamada, H.5    Matsuda, M.6
  • 33
    • 0027988521 scopus 로고
    • The role of cellular transcription factor E2F in the regulation of cdc2 mRNA expression and cell cycle control of human hematopoietic cells
    • Furukawa Y, Terui Y, Sakoe K, Ohta M, Saito M. The role of cellular transcription factor E2F in the regulation of cdc2 mRNA expression and cell cycle control of human hematopoietic cells. J Biol Chem 1994;269:26249-58.
    • (1994) J Biol Chem , vol.269 , pp. 26249-26258
    • Furukawa, Y.1    Terui, Y.2    Sakoe, K.3    Ohta, M.4    Saito, M.5
  • 34
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
    • Frommer M, McDonald LE, Millar DS, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A 1992;89:1827-31.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 1827-1831
    • Frommer, M.1    McDonald, L.E.2    Millar, D.S.3
  • 35
    • 0033580436 scopus 로고    scopus 로고
    • Transcriptional repression of the E2F-1 gene by interferon-α is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes
    • Furukawa Y, Iwase S, Kikuchi J, Nakamura M, Yamada H, Matsuda M. Transcriptional repression of the E2F-1 gene by interferon-α is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes. Oncogene 1999; 18:2003-14.
    • (1999) Oncogene , vol.18 , pp. 2003-2014
    • Furukawa, Y.1    Iwase, S.2    Kikuchi, J.3    Nakamura, M.4    Yamada, H.5    Matsuda, M.6
  • 36
    • 16344380408 scopus 로고    scopus 로고
    • Involvement of the tumor necrosis factor (TNF)/TNF receptor system in leukemic cell apoptosis induced by histone deacetylase inhibitor depsipeptide (FK228)
    • Sutheesophon K, Nishimura N, Kobayashi Y, et al. Involvement of the tumor necrosis factor (TNF)/TNF receptor system in leukemic cell apoptosis induced by histone deacetylase inhibitor depsipeptide (FK228). J Cell Physiol 2005;203: 387-97.
    • (2005) J Cell Physiol , vol.203 , pp. 387-397
    • Sutheesophon, K.1    Nishimura, N.2    Kobayashi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.