Conformational difference between PDE4 apoenzyme and holoenzyme

Biochemistry

Volumn 39, Issue 21, 2000, Pages 6449-6458

  Laliberté, France ^a   Han, Yongxing ^a   Govindarajan, Arvind ^a   Giroux, André ^a   Liu, Susana ^a   Bobechko, Brian ^a   Lario, Paula ^a   Bartlett, Adrienne ^a   Gorseth, Elise ^a   Gresser, Michael ^a   Huang, Zheng ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOENZYME; CYCLIC AMP PHOSPHODIESTERASE; GENE PRODUCT; HOLOENZYME; MAGNESIUM ION; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; NONHUMAN; PRIORITY JOURNAL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; APOENZYMES; BINDING SITES; CELL LINE; CYCLIC AMP; ENERGY TRANSFER; HUMANS; KINETICS; MAGNESIUM; PHOSPHODIESTERASE INHIBITORS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

ANIMALIA;

EID: 0034733021     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992432w     Document Type: Article

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