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Volumn 22, Issue 2, 2004, Pages 79-88

Role of hepatocyte nuclear factors in growth hormone-regulated, sexually dimorphic expression of liver cytochromes P450

Author keywords

Cytochrome P450; GH receptor; Growth hormone; Hepatocyte nuclear factors; Sex dependent liver gene expression

Indexed keywords

CELL NUCLEUS RECEPTOR; CYTOCHROME P450; GROWTH HORMONE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LIVER ENZYME; NUCLEAR FACTOR; PLASMA PROTEIN; RECEPTOR; STAT5B PROTEIN; TRANSCRIPTION FACTOR;

EID: 3142757508     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190410001715172     Document Type: Short Survey
Times cited : (64)

References (91)
  • 1
    • 0033971004 scopus 로고    scopus 로고
    • "Differential expression of gender-dependent hepatic isoforms of cytochrome P-450 by pulse signals in the circulating masculine episodic growth hormone profile of the rat"
    • Agrawal, A.K. and Shapiro, B.H. (2000) "Differential expression of gender-dependent hepatic isoforms of cytochrome P-450 by pulse signals in the circulating masculine episodic growth hormone profile of the rat", J. Pharmacol. Esp. Ther 292, 228-237.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 228-237
    • Agrawal, A.K.1    Shapiro, B.H.2
  • 2
    • 0035931992 scopus 로고    scopus 로고
    • "Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat"
    • Agrawal, A.K. and Shapiro, B.H. (2001) "Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat", Mol. Cell Endocrinol. 173, 167-181.
    • (2001) Mol. Cell Endocrinol. , vol.173 , pp. 167-181
    • Agrawal, A.K.1    Shapiro, B.H.2
  • 3
    • 1542357569 scopus 로고    scopus 로고
    • "Sexual dimorphism of rat liver gene expression: Regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis"
    • Ahluwalia, A., Clodfelter, K.H. and Waxman, D.J. (2004) "Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis", Mol. Endocrinol. 18, 747-760.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 747-760
    • Ahluwalia, A.1    Clodfelter, K.H.2    Waxman, D.J.3
  • 4
    • 0037450505 scopus 로고    scopus 로고
    • "Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors"
    • Akiyama, T.E. and Gonzalez, F.J. (2003) "Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors" , Biochim. Biophys. Acta 1619, 223-234.
    • (2003) Biochim. Biophys. Acta , vol.1619 , pp. 223-234
    • Akiyama, T.E.1    Gonzalez, F.J.2
  • 5
    • 0034671546 scopus 로고    scopus 로고
    • "A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b"
    • Aoki, N. and Matsuda, T. (2000) "A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b", J. Biol. Chem. 275, 39718-39726.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39718-39726
    • Aoki, N.1    Matsuda, T.2
  • 6
    • 0036138705 scopus 로고    scopus 로고
    • "A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: Dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus"
    • Aoki, N. and Matsuda, T. (2002) "A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus", Mol. Endocrinol. 16, 58-69.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 58-69
    • Aoki, N.1    Matsuda, T.2
  • 7
    • 0035445820 scopus 로고    scopus 로고
    • "An enhancer element 6kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors"
    • Bailly, A., Torres-Padilla, M.E., Tinel, A.P. and Weiss, M.C. (2001) "An enhancer element 6kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors", Nucleic Acids Res. 29, 3495-3505.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 3495-3505
    • Bailly, A.1    Torres-Padilla, M.E.2    Tinel, A.P.3    Weiss, M.C.4
  • 8
    • 0032160175 scopus 로고    scopus 로고
    • "IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBP-alpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene"
    • Buggs, C., Nasrin, N., Mode, A., Tollet, P., Zhao, H.F., Gustafsson, J.A. and Alexander-Bridges, M. (1998) "IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBP-alpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene", Mol. Endocrinol. 12, 1294-1309.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1294-1309
    • Buggs, C.1    Nasrin, N.2    Mode, A.3    Tollet, P.4    Zhao, H.F.5    Gustafsson, J.A.6    Alexander-Bridges, M.7
  • 9
    • 0022403303 scopus 로고
    • "Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation"
    • Burkhart, B.A., Harada, N. and Negishi, M. (1985) "Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation", J. Biol. Chem. 260, 15357-15361.
    • (1985) J. Biol. Chem. , vol.260 , pp. 15357-15361
    • Burkhart, B.A.1    Harada, N.2    Negishi, M.3
  • 10
    • 0029962261 scopus 로고    scopus 로고
    • "Liver-enriched transcription factors and hepatocyte differentiation"
    • Cereghini, S. (1996) "Liver-enriched transcription factors and hepatocyte differentiation", FASEB J. 10, 267-282.
    • (1996) FASEB J. , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 11
    • 0028029165 scopus 로고
    • "A transcriptional regulatory element common to a large family of hepatic cytochrome P450 genes is a functional binding site of the orphan receptor HNF-4"
    • Chen, D., Lepar, G. and Kemper, B. (1994a) "A transcriptional regulatory element common to a large family of hepatic cytochrome P450 genes is a functional binding site of the orphan receptor HNF-4", J. Biol. Chem. 269, 5420-5427.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5420-5427
    • Chen, D.1    Lepar, G.2    Kemper, B.3
  • 12
    • 0028148776 scopus 로고
    • "Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos"
    • Chen, W.S., Manova, K., Weinstein, D.C., Duncan, S.A., Plump, A.S., Prezioso, V.R., Bachvarova, R.F. and Darnell, J.E., Jr. (1994b) "Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos", Genes Dev. 8, 2466-2477.
    • (1994) Genes Dev. , vol.8 , pp. 2466-2477
    • Chen, W.S.1    Manova, K.2    Weinstein, D.C.3    Duncan, S.A.4    Plump, A.S.5    Prezioso, V.R.6    Bachvarova, R.F.7    Darnell Jr., J.E.8
  • 13
    • 0242298290 scopus 로고    scopus 로고
    • "Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice"
    • Cheung, C., Akiyama, T.E., Kudo, G. and Gonzalez, F.J. (2003) "Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice", Biochem. Pharmacol. 66, 2011-2020.
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 2011-2020
    • Cheung, C.1    Akiyama, T.E.2    Kudo, G.3    Gonzalez, F.J.4
  • 14
    • 0033303552 scopus 로고    scopus 로고
    • "Growth hormone, but not prolactin, maintains, low-level activation of STAT5a and STAT5b in female rat liver"
    • Choi, H.K. and Waxman, D.J. (1999) "Growth hormone, but not prolactin, maintains, low-level activation of STAT5a and STAT5b in female rat liver", Endocrinology 140, 5126-5135.
    • (1999) Endocrinology , vol.140 , pp. 5126-5135
    • Choi, H.K.1    Waxman, D.J.2
  • 15
    • 0034457934 scopus 로고    scopus 로고
    • "Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: Developmental regulation and role in male-specific liver gene expression"
    • Choi, H.K. and Waxman, D.J. (2000) "Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression", Endocrinology 141, 3245-3255.
    • (2000) Endocrinology , vol.141 , pp. 3245-3255
    • Choi, H.K.1    Waxman, D.J.2
  • 17
    • 0345017786 scopus 로고    scopus 로고
    • "Transcription factors in liver development, differentiation, and regeneration"
    • Costa, R.H., Kalinichenko, V.V., Holterman, A.X. and Wang, X. (2003) "Transcription factors in liver development, differentiation, and regeneration", Hepatology 38, 1331-1347.
    • (2003) Hepatology , vol.38 , pp. 1331-1347
    • Costa, R.H.1    Kalinichenko, V.V.2    Holterman, A.X.3    Wang, X.4
  • 18
    • 0026332810 scopus 로고
    • "Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule"
    • Cunningham, B.C., Ultsch, M., De Vos, A.M., Mulkerrin, M.G., Clauser, K.R. and Wells, J.A. (1991) "Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule", Science 254, 821-825.
    • (1991) Science , vol.254 , pp. 821-825
    • Cunningham, B.C.1    Ultsch, M.2    De Vos, A.M.3    Mulkerrin, M.G.4    Clauser, K.R.5    Wells, J.A.6
  • 19
    • 0030840464 scopus 로고    scopus 로고
    • "STATs and gene regulation"
    • Darnell, J.E.J. (1997) "STATs and gene regulation", Science 277, 1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell, J.E.J.1
  • 20
    • 0033544884 scopus 로고    scopus 로고
    • "STAT5bdeficient mice are growth hormone pulse-resistant. Role of STAT5b in sexspecific liver p450 expression"
    • Davey, H.W., Park, S.H., Grattan, D.R., McLachlan, M.J. and Waxman, D.J. (1999) "STAT5bdeficient mice are growth hormone pulse-resistant. Role of STAT5b in sexspecific liver p450 expression", J. Biol. Chem. 274, 35331-35336.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35331-35336
    • Davey, H.W.1    Park, S.H.2    Grattan, D.R.3    McLachlan, M.J.4    Waxman, D.J.5
  • 21
    • 0034602408 scopus 로고    scopus 로고
    • "Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver"
    • Delesque-Touchard, N., Park, S.H. and Waxman, D.J. (2000) "Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver", J. Biol. Chem. 275, 34173-34182.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34173-34182
    • Delesque-Touchard, N.1    Park, S.H.2    Waxman, D.J.3
  • 22
  • 23
    • 0029820670 scopus 로고    scopus 로고
    • "Constitutive expression of hepatic cytochrome P450 genes"
    • Gonzalez, F.J. and Lee, Y.H. (1996) "Constitutive expression of hepatic cytochrome P450 genes", FASEB J. 10, 1112-1117.
    • (1996) FASEB J. , vol.10 , pp. 1112-1117
    • Gonzalez, F.J.1    Lee, Y.H.2
  • 24
    • 0033305402 scopus 로고    scopus 로고
    • "Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins"
    • Hansen, J.A., Lindberg, K., Hilton, D.J., Nielsen, J.H. and Billestrup, N. (1999) "Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins", Mol. Endocrinol. 13, 1832-1843.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 1832-1843
    • Hansen, J.A.1    Lindberg, K.2    Hilton, D.J.3    Nielsen, J.H.4    Billestrup, N.5
  • 25
    • 0032949466 scopus 로고    scopus 로고
    • "Liver enriched transcription factors and differentiation of hepatocellular carcinoma"
    • Hayashi, Y., Wang, W., Ninomiya, T., Nagano, H., Ohta, K. and Itoh, H. (1999) "Liver enriched transcription factors and differentiation of hepatocellular carcinoma", Mol. Pathol. 52, 19-24.
    • (1999) Mol. Pathol. , vol.52 , pp. 19-24
    • Hayashi, Y.1    Wang, W.2    Ninomiya, T.3    Nagano, H.4    Ohta, K.5    Itoh, H.6
  • 26
    • 0035141324 scopus 로고    scopus 로고
    • "Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis"
    • Hayhurst, G.P., Lee, Y.H., Lambert, G., Ward, J.M. and Gonzalez, F.J. (2001) "Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis", Mol. Cell Biol. 21, 1393-1403.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 27
    • 0035434522 scopus 로고    scopus 로고
    • "Signaling pathways activated by the growth hormone receptor"
    • Herrington, J. and Carter-Su, C. (2001) "Signaling pathways activated by the growth hormone receptor", Trends Endocrinol. Metab. 12, 252-257.
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 252-257
    • Herrington, J.1    Carter-Su, C.2
  • 29
    • 0023135242 scopus 로고
    • "Differential effects of neonatal and adult androgen exposure on the growth hormone secretory pattern in male rats"
    • Jansson, J.O. and Frohman, L.A. (1987) "Differential effects of neonatal and adult androgen exposure on the growth hormone secretory pattern in male rats", Endocrinology 120, 1551-1557.
    • (1987) Endocrinology , vol.120 , pp. 1551-1557
    • Jansson, J.O.1    Frohman, L.A.2
  • 30
    • 0021961002 scopus 로고
    • "Growth hormone (GH)-releasing factor (GRF) pretreatment enhances the GRF-induced GH secretion in rats with the pituitary autotransplanted to the kidney capsule"
    • Jansson, J.O., Carlsson, L. and Isaksson, O.G. (1985) "Growth hormone (GH)-releasing factor (GRF) pretreatment enhances the GRF-induced GH secretion in rats with the pituitary autotransplanted to the kidney capsule", Endocrinology 116, 95-98.
    • (1985) Endocrinology , vol.116 , pp. 95-98
    • Jansson, J.O.1    Carlsson, L.2    Isaksson, O.G.3
  • 31
    • 0034982151 scopus 로고    scopus 로고
    • "Involvement of hepatocyte nuclear factor-4 in the expression of the growth hormone receptor 1A messenger ribonucleic acid in bovine liver"
    • Jiang, H. and Lucy, M.C. (2001) "Involvement of hepatocyte nuclear factor-4 in the expression of the growth hormone receptor 1A messenger ribonucleic acid in bovine liver", Mol. Endocrinol. 15, 1023-1034.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1023-1034
    • Jiang, H.1    Lucy, M.C.2
  • 32
    • 0031127252 scopus 로고    scopus 로고
    • "Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4"
    • Jiang, G., Nepomuceno, L., Yang, Q. and Sladek, F.M. (1997) "Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4", Arch. Biochem. Biophys. 340, 1-9.
    • (1997) Arch. Biochem. Biophys. , vol.340 , pp. 1-9
    • Jiang, G.1    Nepomuceno, L.2    Yang, Q.3    Sladek, F.M.4
  • 33
    • 0035124052 scopus 로고    scopus 로고
    • "Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirusmediated antisense targeting"
    • Jover, R., Bort, R., Gomez-Lechon, M.J. and Castell, J.V. (2001) "Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirusmediated antisense targeting", Hepatology 33, 668-675.
    • (2001) Hepatology , vol.33 , pp. 668-675
    • Jover, R.1    Bort, R.2    Gomez-Lechon, M.J.3    Castell, J.V.4
  • 34
    • 0038482452 scopus 로고    scopus 로고
    • "Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development"
    • Kamiya, A., Inoue, Y. and Gonzalez, F.J. (2003) "Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development", Hepatology 37, 1375-1384.
    • (2003) Hepatology , vol.37 , pp. 1375-1384
    • Kamiya, A.1    Inoue, Y.2    Gonzalez, F.J.3
  • 35
    • 0034801684 scopus 로고    scopus 로고
    • "SOCS proteins: Negative regulators of cytokine signaling"
    • Krebs, D.L. and Hilton, D.J. (2001) "SOCS proteins: negative regulators of cytokine signaling", Stem Cells 19, 378-387.
    • (2001) Stem Cells , vol.19 , pp. 378-387
    • Krebs, D.L.1    Hilton, D.J.2
  • 36
    • 0028820158 scopus 로고
    • "Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential"
    • Ktistaki, E., Ktistakis, N.T., Papadogeorgaki, E. and Talianidis, I. (1995) "Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential", Proc. Natl Acad. Sci. USA 92, 9876-9880.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9876-9880
    • Ktistaki, E.1    Ktistakis, N.T.2    Papadogeorgaki, E.3    Talianidis, I.4
  • 38
    • 0034456218 scopus 로고    scopus 로고
    • "Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the hnf6 gene by growth hormone"
    • Lahuna, O., Rastegar, M., Maiter, D., Thissen, J.P., Lemaigre, F.P. and Rousseau, G.G. (2000) "Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the hnf6 gene by growth hormone", Mol. Endocrinol. 14, 285-294.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 285-294
    • Lahuna, O.1    Rastegar, M.2    Maiter, D.3    Thissen, J.P.4    Lemaigre, F.P.5    Rousseau, G.G.6
  • 39
    • 0028140275 scopus 로고
    • "A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor"
    • Lee, Y.H., Yano, M., Liu, S.Y., Matsunaga, E., Johnson, P.F. and Gonzalez, F.J. (1994) "A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor", Mol. Cell Biol. 14, 1383-1394.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1383-1394
    • Lee, Y.H.1    Yano, M.2    Liu, S.Y.3    Matsunaga, E.4    Johnson, P.F.5    Gonzalez, F.J.6
  • 40
    • 0026535916 scopus 로고
    • "Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion"
    • Legraverend, C., Mode, A., Westin, S., Strom, A., Eguchi, H., Zaphiropoulos, P.G. and Gustafsson, J.A. (1992) "Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion", Mol. Endocrinol. 6, 259-266.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 259-266
    • Legraverend, C.1    Mode, A.2    Westin, S.3    Strom, A.4    Eguchi, H.5    Zaphiropoulos, P.G.6    Gustafsson, J.A.7
  • 42
    • 0034090310 scopus 로고    scopus 로고
    • "Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha"
    • Li, J., Ning, G. and Duncan, S.A. (2000) "Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha", Genes Dev. 14, 464-474.
    • (2000) Genes Dev. , vol.14 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 43
    • 0037113238 scopus 로고    scopus 로고
    • "Hepatocyte nuclear factor 4 response to injury involves a rapid decrease in DNA binding and transactivation via a JAK2 signal transduction pathway"
    • Li, X., Salisbury-Rowswell, J., Murdock, A.D., Forse, R.A. and Burke, P.A. (2002) "Hepatocyte nuclear factor 4 response to injury involves a rapid decrease in DNA binding and transactivation via a JAK2 signal transduction pathway", Biochem. J. 368, 203-211.
    • (2002) Biochem. J. , vol.368 , pp. 203-211
    • Li, X.1    Salisbury-Rowswell, J.2    Murdock, A.D.3    Forse, R.A.4    Burke, P.A.5
  • 45
    • 0022411319 scopus 로고
    • "Hypothalamopituitary regulation of cytochrome P-450(15) beta apoprotein levels in rat liver"
    • MacGeoch, C., Morgan, E.T. and Gustafsson, J.A. (1985) "Hypothalamopituitary regulation of cytochrome P-450(15) beta apoprotein levels in rat liver", Endocrinology 117, 2085-2092.
    • (1985) Endocrinology , vol.117 , pp. 2085-2092
    • MacGeoch, C.1    Morgan, E.T.2    Gustafsson, J.A.3
  • 46
    • 0036290013 scopus 로고    scopus 로고
    • "How important are gender differences in pharmacokinetics?"
    • Meibohm, B., Beierle, I. and Derendorf, H. (2002) "How important are gender differences in pharmacokinetics?", Clin. Pharmacokinet. 41, 329-342.
    • (2002) Clin. Pharmacokinet. , vol.41 , pp. 329-342
    • Meibohm, B.1    Beierle, I.2    Derendorf, H.3
  • 47
    • 0032997468 scopus 로고    scopus 로고
    • "Growth hormone induces insulin-like growth factor-I gene transcription by a synergistic action of STAT5 and HNF-1alpha"
    • Meton, I., Boot, E.P., Sussenbach, J.S. and Steenbergh, P.H. (1999) "Growth hormone induces insulin-like growth factor-I gene transcription by a synergistic action of STAT5 and HNF-1alpha", FEBS Lett. 444, 155-159.
    • (1999) FEBS Lett. , vol.444 , pp. 155-159
    • Meton, I.1    Boot, E.P.2    Sussenbach, J.S.3    Steenbergh, P.H.4
  • 48
    • 0026589377 scopus 로고
    • "Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells"
    • Mietus-Snyder, M., Sladek, F.M., Ginsburg, G.S., Kuo, C.F., Ladias, J.A., Darnell, J.E., Jr. and Karathanasis, S.K. (1992) "Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells", Mol. Cell Biol. 12, 1708-1718.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 1708-1718
    • Mietus-Snyder, M.1    Sladek, F.M.2    Ginsburg, G.S.3    Kuo, C.F.4    Ladias, J.A.5    Darnell Jr., J.E.6    Karathanasis, S.K.7
  • 49
    • 0022974364 scopus 로고
    • "Pretranslational regulation of sexdependent testosterone hydroxylases by growth hormone in mouse liver"
    • Noshiro, M. and Negishi, M. (1986) "Pretranslational regulation of sexdependent testosterone hydroxylases by growth hormone in mouse liver", J. Biol. Chem. 261, 15923-15927.
    • (1986) J. Biol. Chem. , vol.261 , pp. 15923-15927
    • Noshiro, M.1    Negishi, M.2
  • 51
    • 0032964430 scopus 로고    scopus 로고
    • "Gender differences in the responsiveness of the sexdependent isoforms of hepatic P450 to the feminine plasma growth hormone profile"
    • Pampori, N.A. and Shapiro, B.H. (1999) "Gender differences in the responsiveness of the sexdependent isoforms of hepatic P450 to the feminine plasma growth hormone profile", Endocrinology 140, 1245-1254.
    • (1999) Endocrinology , vol.140 , pp. 1245-1254
    • Pampori, N.A.1    Shapiro, B.H.2
  • 52
    • 0035900726 scopus 로고    scopus 로고
    • "Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: Impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression"
    • Park, S.H. and Waxman, D.J. (2001) "Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression", J. Biol. Chem. 276, 43031-43039.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43031-43039
    • Park, S.H.1    Waxman, D.J.2
  • 53
    • 0033548431 scopus 로고    scopus 로고
    • "Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption"
    • Park, S.H., Liu, X., Hennighausen, L., Davey, H.W. and Waxman, D.J. (1999) "Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption", J. Biol. Chem. 274, 7421-7430.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7421-7430
    • Park, S.H.1    Liu, X.2    Hennighausen, L.3    Davey, H.W.4    Waxman, D.J.5
  • 55
    • 0042316837 scopus 로고    scopus 로고
    • "Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK"
    • Piwien Pilipuk, G., Galigniana, M.D. and Schwartz, J. (2003) "Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK", J. Biol. Chem. 278, 35668-35677.
    • (2003) J. Biol. Chem. , vol.278 , pp. 35668-35677
    • Piwien Pilipuk, G.1    Galigniana, M.D.2    Schwartz, J.3
  • 56
    • 0033544899 scopus 로고    scopus 로고
    • "SOCS/CIS protein inhibition of growth hormonestimulated STAT5 signaling by multiple mechanisms"
    • Ram, P.A. and Waxman, D.J. (1999) "SOCS/CIS protein inhibition of growth hormonestimulated STAT5 signaling by multiple mechanisms", J. Biol. Chem. 274, 35553-35561.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35553-35561
    • Ram, P.A.1    Waxman, D.J.2
  • 57
    • 0034456232 scopus 로고    scopus 로고
    • "CCAAT/enhancer-binding proteinalpha is a component of the growth hormone-regulated network of liver transcription factors"
    • Rastegar, M., Rousseau, G.G. and Lemaigre, F.P. (2000) "CCAAT/enhancer-binding proteinalpha is a component of the growth hormone-regulated network of liver transcription factors", Endocrinology 141, 1686-1692.
    • (2000) Endocrinology , vol.141 , pp. 1686-1692
    • Rastegar, M.1    Rousseau, G.G.2    Lemaigre, F.P.3
  • 58
    • 0242349197 scopus 로고    scopus 로고
    • "Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): Requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis"
    • Rhee, J., Inoue, Y., Yoon, J.C., Puigserver, P., Fan, M., Gonzalez, F.J. and Spiegelman, B.M. (2003) "Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis", Proc. Natl Acad. Sci. USA 100, 4012-4017.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4012-4017
    • Rhee, J.1    Inoue, Y.2    Yoon, J.C.3    Puigserver, P.4    Fan, M.5    Gonzalez, F.J.6    Spiegelman, B.M.7
  • 59
    • 0033601376 scopus 로고    scopus 로고
    • "Cooperative regulation of CYP2C12 gene expression by STAT5 and liver-specific factors in female rats"
    • Sasaki, Y., Takahashi, Y., Nakayama, K. and Kamataki, T. (1999) "Cooperative regulation of CYP2C12 gene expression by STAT5 and liver-specific factors in female rats", J. Biol. Chem. 274, 37117-37124.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37117-37124
    • Sasaki, Y.1    Takahashi, Y.2    Nakayama, K.3    Kamataki, T.4
  • 60
    • 0028968479 scopus 로고
    • "Gender differences in drug metabolism regulated by growth hormone"
    • Shapiro, B.H., Agrawal, A.K. and Pampori, N.A. (1995) "Gender differences in drug metabolism regulated by growth hormone", Int. J. Biochem. Cell Biol. 27, 9-20.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 9-20
    • Shapiro, B.H.1    Agrawal, A.K.2    Pampori, N.A.3
  • 61
    • 0033621155 scopus 로고    scopus 로고
    • "Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice"
    • Shih, D.Q., Navas, M.A., Kuwajima, S., Duncan, S.A. and Stoffel, M. (1999) "Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice", Proc. Natl Acad. Sci. USA 96, 10152-10157.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10152-10157
    • Shih, D.Q.1    Navas, M.A.2    Kuwajima, S.3    Duncan, S.A.4    Stoffel, M.5
  • 62
    • 0037040550 scopus 로고    scopus 로고
    • "Coordination of PIC assembly and chromatin remodeling during differentiation-induced gene activation"
    • Soutoglou, E. and Talianidis, I. (2002) "Coordination of PIC assembly and chromatin remodeling during differentiation-induced gene activation", Science 295, 1901-1904.
    • (2002) Science , vol.295 , pp. 1901-1904
    • Soutoglou, E.1    Talianidis, I.2
  • 63
    • 0345245156 scopus 로고    scopus 로고
    • "Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells"
    • Spath, G.F. and Weiss, M.C. (1997) "Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells", Mol. Cell Biol. 17, 1913-1922.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1913-1922
    • Spath, G.F.1    Weiss, M.C.2
  • 64
    • 0030695445 scopus 로고    scopus 로고
    • "The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism"
    • Stoffel, M. and Duncan, S.A. (1997) "The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism", Proc. Natl Acad. Sci. USA 94, 13209-13214.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13209-13214
    • Stoffel, M.1    Duncan, S.A.2
  • 65
    • 0033954261 scopus 로고    scopus 로고
    • "HNF4 and OUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1)"
    • Stroup, D. and Chiang, J.Y. (2000) "HNF4 and OUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1)", J. Lipid Res. 41, 1-11.
    • (2000) J. Lipid Res. , vol.41 , pp. 1-11
    • Stroup, D.1    Chiang, J.Y.2
  • 66
    • 0029094462 scopus 로고
    • "A STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6 beta-hydroxylase gene expression by growth hormone"
    • Subramanian, A., Teixeira, J., Wang, J. and Gil, G. (1995) "A STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6 beta-hydroxylase gene expression by growth hormone", Mol. Cell Biol. 15, 4672-4682.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 4672-4682
    • Subramanian, A.1    Teixeira, J.2    Wang, J.3    Gil, G.4
  • 67
    • 0032077464 scopus 로고    scopus 로고
    • "STAT 5 and NF-Y are involved in expression and growth hormone-mediated sexually dimorphic regulation of cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase"
    • Subramanian, A., Wang, J. and Gil, G. (1998) "STAT 5 and NF-Y are involved in expression and growth hormone-mediated sexually dimorphic regulation of cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase", Nucleic Acids Res. 26, 2173-2178.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2173-2178
    • Subramanian, A.1    Wang, J.2    Gil, G.3
  • 68
    • 0032817449 scopus 로고    scopus 로고
    • "Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver"
    • Sueyoshi, T., Yokomori, N., Korach, K.S. and Negishi, M. (1999) "Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver", Mol. Pharmacol. 56, 473-477.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 473-477
    • Sueyoshi, T.1    Yokomori, N.2    Korach, K.S.3    Negishi, M.4
  • 69
    • 0026707675 scopus 로고
    • "Sex-specific, growth hormoneregulated transcription of the cytochrome P450 2C11 and 2C12 genes"
    • Sundseth, S.S., Alberta, J.A. and Waxman, D.J. (1992) "Sex-specific, growth hormoneregulated transcription of the cytochrome P450 2C11 and 2C12 genes", J. Biol. Chem. 267, 3907-3914.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3907-3914
    • Sundseth, S.S.1    Alberta, J.A.2    Waxman, D.J.3
  • 70
    • 0034750031 scopus 로고    scopus 로고
    • "Temporal relationship between the sexually dimorphic spontaneous GH secretory profiles and hepatic STAT5 activity"
    • Tannenbaum, G.S., Choi, H.K., Gurd, W. and Waxman, D.J. (2001) "Temporal relationship between the sexually dimorphic spontaneous GH secretory profiles and hepatic STAT5 activity", Endocrinology 142, 4599-4606.
    • (2001) Endocrinology , vol.142 , pp. 4599-4606
    • Tannenbaum, G.S.1    Choi, H.K.2    Gurd, W.3    Waxman, D.J.4
  • 76
    • 0030877342 scopus 로고    scopus 로고
    • "Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4"
    • Viollet, B., Kahn, A. and Raymondjean, M. (1997) "Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4", Mol. Cell Biol. 17, 4208-4219.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 4208-4219
    • Viollet, B.1    Kahn, A.2    Raymondjean, M.3
  • 78
    • 0032553439 scopus 로고    scopus 로고
    • "SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4"
    • Wang, J.C., Stafford, J.M. and Granner, D.K. (1998) "SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4" , J. Biol. Chem. 273, 30847-30850.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30847-30850
    • Wang, J.C.1    Stafford, J.M.2    Granner, D.K.3
  • 79
    • 0038241793 scopus 로고    scopus 로고
    • "HNF4: A central regulator of hepatocyte differentiation and function"
    • Watt, A.J., Garrison, W.D. and Duncan, S.A. (2003) "HNF4: a central regulator of hepatocyte differentiation and function", Hepatology 37, 1249-1253.
    • (2003) Hepatology , vol.37 , pp. 1249-1253
    • Watt, A.J.1    Garrison, W.D.2    Duncan, S.A.3
  • 80
    • 0033655613 scopus 로고    scopus 로고
    • "Growth hormone pulse-activated STAT5 signalling: A unique regulatory mechanism governing sexual dimorphism of liver gene expression"
    • discussion 75-81
    • Waxman, D.J. (2000) "Growth hormone pulse-activated STAT5 signalling: a unique regulatory mechanism governing sexual dimorphism of liver gene expression", Novartis Found Symp. 227, 61-74, discussion 75-81.
    • (2000) Novartis Found Symp. , vol.227 , pp. 61-74
    • Waxman, D.J.1
  • 81
    • 0002440739 scopus 로고    scopus 로고
    • "Growth hormone action: Signaling via a JAK/STATcoupled receptor"
    • Conn, P.M. and Means, A., eds. (Humana Press, Totowa, NJ)
    • Waxman, D.J. and Frank, S.J. (2000) "Growth hormone action: signaling via a JAK/STATcoupled receptor", In: Conn, P.M. and Means, A., eds, Principles of Molecular Regulation (Humana Press, Totowa, NJ), pp 55-83.
    • (2000) Principles of Molecular Regulation , pp. 55-83
    • Waxman, D.J.1    Frank, S.J.2
  • 82
    • 0023792635 scopus 로고
    • "Adult male-specific and neonatally programmed rat hepatic-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression"
    • Waxman, D.J., LeBlanc, G.A., Morrissey, J.J., Staunton, J. and Lapenson, D.P. (1988) "Adult male-specific and neonatally programmed rat hepatic-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression", J. Biol. Chem. 263, 11396-11406.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11396-11406
    • Waxman, D.J.1    LeBlanc, G.A.2    Morrissey, J.J.3    Staunton, J.4    Lapenson, D.P.5
  • 83
    • 0025945671 scopus 로고
    • "Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450"
    • Waxman, D.J., Pampori, N.A., Ram, P.A., Agrawal, A.K. and Shapiro, B.H. (1991) "Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450", Proc. Natl Acad. Sci. USA 88, 6868-6872.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6868-6872
    • Waxman, D.J.1    Pampori, N.A.2    Ram, P.A.3    Agrawal, A.K.4    Shapiro, B.H.5
  • 84
    • 0028820894 scopus 로고
    • "Growth hormone regulation of male-specific rat liver P450s 2A2 and 3A2: Induction by intermittent growth hormone pulses in male but not female rats rendered growth hormone deficient by neonatal monosodium glutamate"
    • Waxman, D.J., Ram, P.A., Pampori, N.A. and Shapiro, B.H. (1995a) "Growth hormone regulation of male-specific rat liver P450s 2A2 and 3A2: induction by intermittent growth hormone pulses in male but not female rats rendered growth hormone deficient by neonatal monosodium glutamate", Mol. Pharmacol. 48, 790-797.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 790-797
    • Waxman, D.J.1    Ram, P.A.2    Pampori, N.A.3    Shapiro, B.H.4
  • 85
    • 0029032210 scopus 로고
    • "Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liverexpressed. Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription"
    • Waxman, D.J., Ram, P.A., Park, S.H. and Choi, H.K. (1995b) "Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liverexpressed. Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription", J. Biol. Chem. 270, 13262-13270.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13262-13270
    • Waxman, D.J.1    Ram, P.A.2    Park, S.H.3    Choi, H.K.4
  • 86
    • 3142765079 scopus 로고    scopus 로고
    • "Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4∝-deficient mice"
    • (in press)
    • Wiwi, C.A., Gupte, M. and Waxman, D.J. (2004) "Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4∝-deficient mice", Mol. Endocritiol. (in press).
    • (2004) Mol. Endocrinol.
    • Wiwi, C.A.1    Gupte, M.2    Waxman, D.J.3
  • 88
    • 0030735948 scopus 로고    scopus 로고
    • "Transcriptional regulation by HNF-4 of the steroid 15alphahydroxylase P450 (Cyp2a-4) gene in mouse liver"
    • Yokomori, N., Nishio, K., Aida, K. and Negishi, M. (1997) "Transcriptional regulation by HNF-4 of the steroid 15alphahydroxylase P450 (Cyp2a-4) gene in mouse liver", J. Steroid Biochem. Mol. Biol. 62, 307-314.
    • (1997) J. Steroid Biochem. Mol. Biol. , vol.62 , pp. 307-314
    • Yokomori, N.1    Nishio, K.2    Aida, K.3    Negishi, M.4
  • 89
    • 0024996092 scopus 로고
    • "A specific cis-acting element regulates in vitro transcription of sex-dependent mouse steroid 16 alphahydroxylase (C-P450(16 alpha)) gene"
    • Yoshioka, H., Lang, M., Wong, G. and Negishi, M. (1990) "A specific cis-acting element regulates in vitro transcription of sex-dependent mouse steroid 16 alphahydroxylase (C-P450(16 alpha)) gene", J. Biol. Chem. 265, 14612-14617.
    • (1990) J. Biol. Chem. , vol.265 , pp. 14612-14617
    • Yoshioka, H.1    Lang, M.2    Wong, G.3    Negishi, M.4
  • 90
    • 0034695690 scopus 로고    scopus 로고
    • "Janus kinase 2-dependent activation of p38 mitogenactivated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal re-organization and mitogenesis"
    • Zhu, T. and Lobie, P.E. (2000) "Janus kinase 2-dependent activation of p38 mitogenactivated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal re-organization and mitogenesis", J. Biol. Chem. 275, 2103-2114.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2103-2114
    • Zhu, T.1    Lobie, P.E.2
  • 91
    • 0034907888 scopus 로고    scopus 로고
    • "Signal transduction via the growth hormone receptor"
    • Zhu, T., Goh, E.L., Graichen, R., Ling, L. and Lobie, P.E. (2001) "Signal transduction via the growth hormone receptor", Cell Signal 13, 599-616.
    • (2001) Cell Signal , vol.13 , pp. 599-616
    • Zhu, T.1    Goh, E.L.2    Graichen, R.3    Ling, L.4    Lobie, P.E.5


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